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Priscilla K. Brastianos
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Journal Articles

CDK4/6 Inhibition Sensitizes Intracranial Tumors to PD-1 Blockade in Preclinical Models of Brain Metastasis

Naema Nayyar, Magali A. de Sauvage, Jane Chuprin, Emily M. Sullivan, Mohini Singh, Consuelo Torrini, Britney S. Zhang, Sushobhana Bandyopadhyay, Keith A. Daniels, Christopher Alvarez-Breckenridge, Ashish Dahal, Michael A. Brehm, Priscilla K. Brastianos
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (2): 420–435.
https://doi.org/10.1158/1078-0432.CCR-23-0433
Published: 17 January 2024
View article titled, CDK4/6 Inhibition Sensitizes Intracranial Tumors to PD-1 Blockade in Preclinical Models of Brain Metastasis
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Includes: Supplementary data
Journal Articles

Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non–Small Cell Lung Cancer

Joshua K. Sabari, Vamsidhar Velcheti, Kazuhide Shimizu, Matthew R. Strickland, Rebecca S. Heist, Mohini Singh, Naema Nayyar, Anita Giobbie-Hurder, Subba R. Digumarthy, Justin F. Gainor, Anant P. Rajan, Edwin Nieblas-Bedolla, Aaron C. Burns, Jill Hallin, Peter Olson, James G. Christensen, Sylvia C. Kurz, Priscilla K. Brastianos, Hiroaki Wakimoto
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (15): 3318–3328.
https://doi.org/10.1158/1078-0432.CCR-22-0383
Published: 02 August 2022
View article titled, Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRAS<sup>G12C</sup>-Mutant Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in PIK3CA-Mutant Breast Cancer Brain Metastases

Franziska M. Ippen, Christopher A. Alvarez-Breckenridge, Benjamin M. Kuter, Alexandria L. Fink, Ivanna V. Bihun, Matthew Lastrapes, Tristan Penson, Stephen P. Schmidt, Gregory R. Wojtkiewicz, Jianfang Ning, Megha Subramanian, Anita Giobbie-Hurder, Maria Martinez-Lage, Scott L. Carter, Daniel P. Cahill, Hiroaki Wakimoto, Priscilla K. Brastianos
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (11): 3374–3383.
https://doi.org/10.1158/1078-0432.CCR-18-3049
Published: 03 June 2019
View article titled, The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in <em>PIK3CA</em>-Mutant Breast Cancer Brain Metastases
Open the PDF for The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in <em>PIK3CA</em>-Mutant Breast Cancer Brain Metastases in another window
Includes: Supplementary data
Journal Articles

Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival

Lijie Zhai, Erik Ladomersky, Kristen L. Lauing, Meijing Wu, Matthew Genet, Galina Gritsina, Balázs Győrffy, Priscilla K. Brastianos, David C. Binder, Jeffrey A. Sosman, Francis J. Giles, Charles D. James, Craig Horbinski, Roger Stupp, Derek A. Wainwright
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (21): 6650–6660.
https://doi.org/10.1158/1078-0432.CCR-17-0120
Published: 31 October 2017
View article titled, Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival
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Includes: Supplementary data
Journal Articles

Landscape of Genomic Alterations in Pituitary Adenomas

Wenya Linda Bi, Peleg Horowitz, Noah F. Greenwald, Malak Abedalthagafi, Pankaj K. Agarwalla, Wiliam J. Gibson, Yu Mei, Steven E. Schumacher, Uri Ben-David, Aaron Chevalier, Scott Carter, Grace Tiao, Priscilla K. Brastianos, Azra H. Ligon, Matthew Ducar, Laura MacConaill, Edward R. Laws, Jr, Sandro Santagata, Rameen Beroukhim, Ian F. Dunn
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (7): 1841–1851.
https://doi.org/10.1158/1078-0432.CCR-16-0790
Published: 02 April 2017
View article titled, Landscape of Genomic Alterations in Pituitary Adenomas
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Includes: Supplementary data
Journal Articles

Alterations in Pericyte Subpopulations Are Associated with Elevated Blood–Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer

L. Tiffany Lyle, Paul R. Lockman, Chris E. Adkins, Afroz Shareef Mohammad, Emily Sechrest, Emily Hua, Diane Palmieri, David J. Liewehr, Seth M. Steinberg, Wojciech Kloc, Ewa Izycka-Swieszewska, Renata Duchnowska, Naema Nayyar, Priscilla K. Brastianos, Patricia S. Steeg, Brunilde Gril
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (21): 5287–5299.
https://doi.org/10.1158/1078-0432.CCR-15-1836
Published: 31 October 2016
View article titled, Alterations in Pericyte Subpopulations Are Associated with Elevated Blood–Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer
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Includes: Supplementary data
Journal Articles

PLEKHA5: A Key to Unlock the Blood–Brain Barrier?

Sylvia C. Eisele, Corey M. Gill, Ganesh M. Shankar, Priscilla K. Brastianos
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (9): 1978–1980.
https://doi.org/10.1158/1078-0432.CCR-14-2604
Published: 30 April 2015
View article titled, PLEKHA5: A Key to Unlock the Blood–Brain Barrier?
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