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Journal Articles

Phase II Clinical Trial of Pembrolizumab and Chemotherapy Reveals Distinct Transcriptomic Profiles by Radiologic Response in Metastatic Triple-Negative Breast Cancer

Avia D. Wilkerson, Prerana Bangalore Parthasarathy, Nickolas Stabellini, Carley Mitchell, Paul G. Pavicic, Jr, Pingfu Fu, Amit Rupani, Hana Husic, Patricia A. Rayman, Shadi Swaidani, Jame Abraham, G. Thomas Budd, Halle Moore, Zahraa Al-Hilli, Jennifer S. Ko, Joseph Baar, Timothy A. Chan, Tyler Alban, C. Marcela Diaz-Montero, Alberto J. Montero
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (1): 82–93.
https://doi.org/10.1158/1078-0432.CCR-23-1349
Published: 05 January 2024
View articletitled, Phase II Clinical Trial of Pembrolizumab and Chemotherapy Reveals Distinct Transcriptomic Profiles by Radiologic Response in Metastatic Triple-Negative Breast Cancer
Open the PDF for Phase II Clinical Trial of Pembrolizumab and Chemotherapy Reveals Distinct Transcriptomic Profiles by Radiologic Response in Metastatic Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Novel Radiomic Measurements of Tumor-Associated Vasculature Morphology on Clinical Imaging as a Biomarker of Treatment Response in Multiple Cancers

Nathaniel Braman, Prateek Prasanna, Kaustav Bera, Mehdi Alilou, Mohammadhadi Khorrami, Patrick Leo, Maryam Etesami, Manasa Vulchi, Paulette Turk, Amit Gupta, Prantesh Jain, Pingfu Fu, Nathan Pennell, Vamsidhar Velcheti, Jame Abraham, Donna Plecha, Anant Madabhushi
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (20): 4410–4424.
https://doi.org/10.1158/1078-0432.CCR-21-4148
Published: 14 October 2022
View articletitled, Novel Radiomic Measurements of Tumor-Associated Vasculature Morphology on Clinical Imaging as a Biomarker of Treatment Response in Multiple Cancers
Open the PDF for Novel Radiomic Measurements of Tumor-Associated Vasculature Morphology on Clinical Imaging as a Biomarker of Treatment Response in Multiple Cancers in another window
Includes: Supplementary data
Journal Articles

Adding Base-Excision Repair Inhibitor TRC102 to Standard Pemetrexed–Platinum–Radiation in Patients with Advanced Nonsquamous Non–Small Cell Lung Cancer: Results of a Phase I Trial

Tithi Biswas, Afshin Dowlati, Charles A. Kunos, John J. Pink, Nancy L. Oleinick, Shakun Malik, Pingfu Fu, Shufen Cao, Debora S. Bruno, David L. Bajor, Monaliben Patel, Stanton L. Gerson, Mitchell Machtay
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (4): 646–652.
https://doi.org/10.1158/1078-0432.CCR-21-2025
Published: 15 February 2022
View articletitled, Adding Base-Excision Repair Inhibitor TRC102 to Standard Pemetrexed–Platinum–Radiation in Patients with Advanced Nonsquamous Non–Small Cell Lung Cancer: Results of a Phase I Trial
Open the PDF for Adding Base-Excision Repair Inhibitor TRC102 to Standard Pemetrexed–Platinum–Radiation in Patients with Advanced Nonsquamous Non–Small Cell Lung Cancer: Results of a Phase I Trial in another window
Includes: Supplementary data
Journal Articles

Computationally Derived Image Signature of Stromal Morphology Is Prognostic of Prostate Cancer Recurrence Following Prostatectomy in African American Patients

Hersh K. Bhargava, Patrick Leo, Robin Elliott, Andrew Janowczyk, Jon Whitney, Sanjay Gupta, Pingfu Fu, Kosj Yamoah, Francesca Khani, Brian D. Robinson, Timothy R. Rebbeck, Michael Feldman, Priti Lal, Anant Madabhushi
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (8): 1915–1923.
https://doi.org/10.1158/1078-0432.CCR-19-2659
Published: 15 April 2020
View articletitled, Computationally Derived Image Signature of Stromal Morphology Is Prognostic of Prostate Cancer Recurrence Following Prostatectomy in African American Patients
Open the PDF for Computationally Derived Image Signature of Stromal Morphology Is Prognostic of Prostate Cancer Recurrence Following Prostatectomy in African American Patients in another window
Includes: Supplementary data
Journal Articles

Spatial Architecture and Arrangement of Tumor-Infiltrating Lymphocytes for Predicting Likelihood of Recurrence in Early-Stage Non–Small Cell Lung Cancer

Germán Corredor, Xiangxue Wang, Yu Zhou, Cheng Lu, Pingfu Fu, Konstantinos Syrigos, David L. Rimm, Michael Yang, Eduardo Romero, Kurt A. Schalper, Vamsidhar Velcheti, Anant Madabhushi
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (5): 1526–1534.
https://doi.org/10.1158/1078-0432.CCR-18-2013
Published: 01 March 2019
View articletitled, Spatial Architecture and Arrangement of Tumor-Infiltrating Lymphocytes for Predicting Likelihood of Recurrence in Early-Stage Non–Small Cell Lung Cancer
Open the PDF for Spatial Architecture and Arrangement of Tumor-Infiltrating Lymphocytes for Predicting Likelihood of Recurrence in Early-Stage Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Low PIAS3 Expression in Malignant Mesothelioma Is Associated with Increased STAT3 Activation and Poor Patient Survival

Snehal Dabir, Amy Kluge, Adam Kresak, Michael Yang, Pingfu Fu, Bernd Groner, Gary Wildey, Afshin Dowlati
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (19): 5124–5132.
https://doi.org/10.1158/1078-0432.CCR-14-1233
Published: 30 September 2014
View articletitled, Low PIAS3 Expression in Malignant Mesothelioma Is Associated with Increased STAT3 Activation and Poor Patient Survival
Open the PDF for Low PIAS3 Expression in Malignant Mesothelioma Is Associated with Increased STAT3 Activation and Poor Patient Survival in another window
Journal Articles

A Vasculature-Targeting Regimen of Preoperative Docetaxel with or without Bevacizumab for Locally Advanced Breast Cancer: Impact on Angiogenic Biomarkers

Joseph Baar, Paula Silverman, Janice Lyons, Pingfu Fu, Fadi Abdul-Karim, Nicholas Ziats, Jay Wasman, Paul Hartman, John Jesberger, Leda Dumadag, Erin Hohler, Rosemary Leeming, Robert Shenk, Helen Chen, Keith McCrae, Afshin Dowlati, Scot C. Remick, Beth Overmoyer
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (10): 3583–3590.
https://doi.org/10.1158/1078-0432.CCR-08-2917
Published: 18 May 2009
View articletitled, A Vasculature-Targeting Regimen of Preoperative Docetaxel with or without Bevacizumab for Locally Advanced Breast Cancer: Impact on Angiogenic Biomarkers
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Journal Articles

Inflammatory Breast Cancer as a Model Disease to Study Tumor Angiogenesis: Results of a Phase IB Trial of Combination SU5416 and Doxorubicin

Beth Overmoyer, Pingfu Fu, Charles Hoppel, Tomas Radivoyevitch, Robert Shenk, Marjie Persons, Paula Silverman, Kelly Robertson, Nicholas P. Ziats, Jay K. Wasman, Fadi W. Abdul-Karim, John A. Jesberger, Jeffrey Duerk, Paul Hartman, Shelli Hanks, Jonathan Lewin, Afshin Dowlati, Keith McCrae, Percy Ivy, Scot C. Remick
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19): 5862–5868.
https://doi.org/10.1158/1078-0432.CCR-07-0688
Published: 01 October 2007
View articletitled, Inflammatory Breast Cancer as a Model Disease to Study Tumor Angiogenesis: Results of a Phase IB Trial of Combination SU5416 and Doxorubicin
Open the PDF for Inflammatory Breast Cancer as a Model Disease to Study Tumor Angiogenesis: Results of a Phase IB Trial of Combination SU5416 and Doxorubicin in another window