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Journal Articles

Clinicopathologic Features, Molecular Landscape, and Prognostic Implications of Ovarian Low-Grade Serous Tumors with Histologic Transformation

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M. Herman Chui, Eun-Young Kang, Ryan M. Kahn, Sarah Chiang, Qin Zhou, Alexia Iasonos, Beryl Manning-Geist, Pier Selenica, Arnaud Da Cruz Paula, Kara Long Roche, Britta Weigelt, Rachel N. Grisham
Journal: Clinical Cancer Research
Clin Cancer Res (2025)
https://doi.org/10.1158/1078-0432.CCR-24-3168
Published: 06 May 2025
View articletitled, Clinicopathologic Features, Molecular Landscape, and Prognostic Implications of Ovarian Low-Grade Serous Tumors with Histologic Transformation
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Includes: Supplementary data
Journal Articles

A Phase II Study of Fulvestrant plus Abemaciclib in Hormone Receptor–Positive Advanced or Recurrent Endometrial Cancer

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Angela K. Green, Qin Zhou, Alexia Iasonos, William A. Zammarrelli, III, Britta Weigelt, Lora H. Ellenson, Rashmi Chhetri-Long, Pooja Shah, Jade Loh, Vania Hom, Pier Selenica, Joseph Erinjeri, Iva Petkovska, Sarat Chandarlapaty, Seth Cohen, Rachel Grisham, Jason Konner, Maria M. Rubinstein, William Tew, Tiffany Troso-Sandoval, Carol Aghajanian, Vicky Makker
Journal: Clinical Cancer Research
Clin Cancer Res OF1–OF9.
https://doi.org/10.1158/1078-0432.CCR-24-1999
Published: 10 December 2024
View articletitled, A Phase II Study of Fulvestrant plus Abemaciclib in Hormone Receptor–Positive Advanced or Recurrent Endometrial Cancer
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Includes: Supplementary data
Journal Articles

A Multiparameter Molecular Classifier to Predict Response to Neoadjuvant Lapatinib plus Trastuzumab without Chemotherapy in HER2+ Breast Cancer

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Jamunarani Veeraraghavan, Carolina Gutierrez, Carmine De Angelis, Robert Davis, Tao Wang, Tomas Pascual, Pier Selenica, Katherine Sanchez, Hiroaki Nitta, Monesh Kapadia, Anne C. Pavlick, Patricia Galvan, Brent Rexer, Andres Forero-Torres, Rita Nanda, Anna M. Storniolo, Ian E. Krop, Matthew P. Goetz, Julie R. Nangia, Antonio C. Wolff, Britta Weigelt, Jorge S. Reis-Filho, Susan G. Hilsenbeck, Aleix Prat, C. Kent Osborne, Rachel Schiff, Mothaffar F. Rimawi
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (16): 3101–3109.
https://doi.org/10.1158/1078-0432.CCR-22-3753
Published: 15 August 2023
View articletitled, A Multiparameter Molecular Classifier to Predict Response to Neoadjuvant Lapatinib plus Trastuzumab without Chemotherapy in HER2+ Breast Cancer
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Includes: Supplementary data
Journal Articles

High-Sensitivity Mutation Analysis of Cell-Free DNA for Disease Monitoring in Endometrial Cancer

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Charles W. Ashley, Pier Selenica, Juber Patel, Michelle Wu, Josip Nincevic, Yulia Lakhman, Qin Zhou, Ronak H. Shah, Michael F. Berger, Arnaud Da Cruz Paula, David N. Brown, Antonio Marra, Alexia Iasonos, Amir Momeni-Boroujeni, Kaled M. Alektiar, Kara Long Roche, Oliver Zivanovic, Jennifer J. Mueller, Dmitriy Zamarin, Vance A. Broach, Yukio Sonoda, Mario M. Leitao, Jr, Claire F. Friedman, Elizabeth Jewell, Jorge S. Reis-Filho, Lora H. Ellenson, Carol Aghajanian, Nadeem R. Abu-Rustum, Karen Cadoo, Britta Weigelt
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (2): 410–421.
https://doi.org/10.1158/1078-0432.CCR-22-1134
Published: 17 January 2023
View articletitled, High-Sensitivity Mutation Analysis of Cell-Free DNA for Disease Monitoring in Endometrial Cancer
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Includes: Supplementary data
Journal Articles

Microsatellite Instability–High Endometrial Cancers with MLH1 Promoter Hypermethylation Have Distinct Molecular and Clinical Profiles

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Beryl L. Manning-Geist, Ying L. Liu, Kelly A. Devereaux, Arnaud Da Cruz Paula, Qin C. Zhou, Weining Ma, Pier Selenica, Ozge Ceyhan-Birsoy, Lea A. Moukarzel, Timothy Hoang, Sushmita Gordhandas, Maria M. Rubinstein, Claire F. Friedman, Carol Aghajanian, Nadeem R. Abu-Rustum, Zsofia K. Stadler, Jorge S. Reis-Filho, Alexia Iasonos, Dmitriy Zamarin, Lora H. Ellenson, Yulia Lakhman, Diana L. Mandelker, Britta Weigelt
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (19): 4302–4311.
https://doi.org/10.1158/1078-0432.CCR-22-0713
Published: 03 October 2022
View articletitled, Microsatellite Instability–High Endometrial Cancers with MLH1 Promoter Hypermethylation Have Distinct Molecular and Clinical Profiles
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Includes: Supplementary data
Journal Articles

Morphologic and Genomic Characteristics of Breast Cancers Occurring in Individuals with Lynch Syndrome

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Christopher J. Schwartz, Edaise M. da Silva, Antonio Marra, Andrea M. Gazzo, Pier Selenica, Vikas K. Rai, Diana Mandelker, Fresia Pareja, Maksym Misyura, Timothy M. D'Alfonso, Edi Brogi, Pamela Drullinsky, Pedram Razavi, Mark E. Robson, Joshua Z. Drago, Hannah Y. Wen, Liying Zhang, Britta Weigelt, Jinru Shia, Jorge S. Reis-Filho, Hong Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (2): 404–413.
https://doi.org/10.1158/1078-0432.CCR-21-2027
Published: 19 January 2022
View articletitled, Morphologic and Genomic Characteristics of Breast Cancers Occurring in Individuals with Lynch Syndrome
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Includes: Supplementary data
Journal Articles

Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer

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Carmine De Angelis, Xiaoyong Fu, Maria Letizia Cataldo, Agostina Nardone, Resel Pereira, Jamunarani Veeraraghavan, Sarmistha Nanda, Lanfang Qin, Vidyalakshmi Sethunath, Tao Wang, Susan G. Hilsenbeck, Matteo Benelli, Ilenia Migliaccio, Cristina Guarducci, Luca Malorni, Lacey M. Litchfield, Jiangang Liu, Joshua Donaldson, Pier Selenica, David N. Brown, Britta Weigelt, Jorge S. Reis-Filho, Ben H. Park, Sara A. Hurvitz, Dennis J. Slamon, Mothaffar F. Rimawi, Valerie M. Jansen, Rinath Jeselsohn, C. Kent Osborne, Rachel Schiff
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (17): 4870–4882.
https://doi.org/10.1158/1078-0432.CCR-19-4191
Published: 01 September 2021
View articletitled, Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer
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Includes: Supplementary data
Journal Articles

Correction: Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer

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Carmine De Angelis, Xiaoyong Fu, Maria Letizia Cataldo, Agostina Nardone, Resel Pereira, Jamunarani Veeraraghavan, Sarmistha Nanda, Lanfang Qin, Vidyalakshmi Sethunath, Tao Wang, Susan G. Hilsenbeck, Matteo Benelli, Ilenia Migliaccio, Cristina Guarducci, Luca Malorni, Lacey M. Litchfield, Jiangang Liu, Joshua Donaldson, Pier Selenica, David N. Brown, Britta Weigelt, Jorge S. Reis-Filho, Ben H. Park, Sara A. Hurvitz, Dennis J. Slamon, Mothaffar F. Rimawi, Valerie M. Jansen, Rinath Jeselsohn, C. Kent Osborne, Rachel Schiff
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (17): 4939.
https://doi.org/10.1158/1078-0432.CCR-21-2431
Published: 01 September 2021
View articletitled, Correction: Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer
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Journal Articles

Whole-Exome Sequencing Analysis of the Progression from Non–Low-Grade Ductal Carcinoma In Situ to Invasive Ductal Carcinoma

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Fresia Pareja, David N. Brown, Ju Youn Lee, Arnaud Da Cruz Paula, Pier Selenica, Rui Bi, Felipe C. Geyer, Andrea Gazzo, Edaise M. da Silva, Mahsa Vahdatinia, Anthe A. Stylianou, Lorenzo Ferrando, Hannah Y. Wen, James B. Hicks, Britta Weigelt, Jorge S. Reis-Filho
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (14): 3682–3693.
https://doi.org/10.1158/1078-0432.CCR-19-2563
Published: 15 July 2020
View articletitled, Whole-Exome Sequencing Analysis of the Progression from Non–Low-Grade Ductal Carcinoma In Situ to Invasive Ductal Carcinoma
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Includes: Supplementary data
Journal Articles

Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection

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Wungki Park, Jiapeng Chen, Joanne F. Chou, Anna M. Varghese, Kenneth H. Yu, Winston Wong, Marinela Capanu, Vinod Balachandran, Caitlin A. McIntyre, Imane El Dika, Danny N. Khalil, James J. Harding, Nima Ghalehsari, Zoe McKinnell, Sree B. Chalasani, Vladimir Makarov, Pier Selenica, Xin Pei, Nicolas Lecomte, David P. Kelsen, Ghassan K. Abou-Alfa, Mark E. Robson, Liying Zhang, Michael F. Berger, Nikolaus Schultz, Timothy A. Chan, Simon N. Powell, Jorge S. Reis-Filho, Christine A. Iacobuzio-Donahue, Nadeem Riaz, Eileen M. O'Reilly
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (13): 3239–3247.
https://doi.org/10.1158/1078-0432.CCR-20-0418
Published: 01 July 2020
View articletitled, Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection
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Includes: Supplementary data
Journal Articles

Lobular Carcinomas In Situ Display Intralesion Genetic Heterogeneity and Clonal Evolution in the Progression to Invasive Lobular Carcinoma

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Ju Youn Lee, Michail Schizas, Felipe C. Geyer, Pier Selenica, Salvatore Piscuoglio, Rita A. Sakr, Charlotte K.Y. Ng, Jose V. Scarpa Carniello, Russell Towers, Dilip D. Giri, Victor P. de Andrade, Anastasios D. Papanastasiou, Agnes Viale, Reuben S. Harris, David B. Solit, Britta Weigelt, Jorge S. Reis-Filho, Tari A. King
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (2): 674–686.
https://doi.org/10.1158/1078-0432.CCR-18-1103
Published: 15 January 2019
View articletitled, Lobular Carcinomas In Situ Display Intralesion Genetic Heterogeneity and Clonal Evolution in the Progression to Invasive Lobular Carcinoma
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Includes: Supplementary data
Journal Articles

Diverse BRCA1 and BRCA2 Reversion Mutations in Circulating Cell-Free DNA of Therapy-Resistant Breast or Ovarian Cancer

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Britta Weigelt, Iñaki Comino-Méndez, Ino de Bruijn, Lei Tian, Jane L. Meisel, Isaac García-Murillas, Charlotte Fribbens, Ros Cutts, Luciano G. Martelotto, Charlotte K.Y. Ng, Raymond S. Lim, Pier Selenica, Salvatore Piscuoglio, Carol Aghajanian, Larry Norton, Rajmohan Murali, David M. Hyman, Laetitia Borsu, Maria E. Arcila, Jason Konner, Jorge S. Reis-Filho, Roger A. Greenberg, Mark E. Robson, Nicholas C. Turner
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (21): 6708–6720.
https://doi.org/10.1158/1078-0432.CCR-17-0544
Published: 31 October 2017
View articletitled, Diverse BRCA1 and BRCA2 Reversion Mutations in Circulating Cell-Free DNA of Therapy-Resistant Breast or Ovarian Cancer
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Includes: Supplementary data