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Journal Articles

The Impact of PIK3R1 Mutations and Insulin–PI3K–Glycolytic Pathway Regulation in Prostate Cancer

Clin Cancer Res (2022) 28 (16): 3603–3617.

https://doi.org/10.1158/1078-0432.CCR-21-4272

Published: 15 August 2022

View article titled, The Impact of PIK3R1 Mutations and Insulin–PI3K–Glycolytic Pathway Regulation in Prostate Cancer

Includes: Supplementary data

Journal Articles

Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors

Clin Cancer Res (2022) 28 (2): 318–326.

https://doi.org/10.1158/1078-0432.CCR-21-2577

Published: 15 January 2022

View article titled, Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors

Includes: Supplementary data

Journal Articles

Abiraterone Acetate Induces CREB1 Phosphorylation and Enhances the Function of the CBP-p300 Complex, Leading to Resistance in Prostate Cancer Cells

Wenting Pan, Zhouwei Zhang, Hannah Kimball, Fangfang Qu, Kyler Berlind, Konrad H. Stopsack, Gwo-Shu Mary Lee, Toni K. Choueiri, Philip W. Kantoff

Clin Cancer Res (2021) 27 (7): 2087–2099.

https://doi.org/10.1158/1078-0432.CCR-20-4391

Published: 01 April 2021

View article titled, Abiraterone Acetate Induces CREB1 Phosphorylation and Enhances the Function of the CBP-p300 Complex, Leading to Resistance in Prostate Cancer Cells

Includes: Supplementary data

Journal Articles

Attenuation of SRC Kinase Activity Augments PARP Inhibitor–mediated Synthetic Lethality in BRCA2-altered Prostate Tumors

Goutam Chakraborty, Nabeela Khan Patail, Rahim Hirani, Subhiksha Nandakumar, Ying Z. Mazzu, Yuki Yoshikawa, Mohammad Atiq, Lina E. Jehane, Konrad H. Stopsack, Gwo-Shu Mary Lee, Wassim Abida, Michael J. Morris, Lorelei A. Mucci, Daniel Danila, Philip W. Kantoff

Clin Cancer Res (2021) 27 (6): 1792–1806.

https://doi.org/10.1158/1078-0432.CCR-20-2483

Published: 15 March 2021

View article titled, Attenuation of SRC Kinase Activity Augments PARP Inhibitor–mediated Synthetic Lethality in BRCA2-altered Prostate Tumors

Includes: Supplementary data

Journal Articles

Dual Blockade of c-MET and the Androgen Receptor in Metastatic Castration-resistant Prostate Cancer: A Phase I Study of Concurrent Enzalutamide and Crizotinib

Abhishek Tripathi, Jeffrey G. Supko, Kathryn P. Gray, Zachary J. Melnick, Meredith M. Regan, Mary-Ellen Taplin, Atish D. Choudhury, Mark M. Pomerantz, Joaquim Bellmunt, Channing Yu, Zijie Sun, Sandy Srinivas, Philip W. Kantoff, Christopher J. Sweeney, Lauren C. Harshman

Clin Cancer Res (2020) 26 (23): 6122–6131.

https://doi.org/10.1158/1078-0432.CCR-20-2306

Published: 01 December 2020

View article titled, Dual Blockade of c-MET and the Androgen Receptor in Metastatic Castration-resistant Prostate Cancer: A Phase I Study of Concurrent Enzalutamide and Crizotinib

Includes: Supplementary data

Journal Articles

Multiplex Immunofluorescence in Formalin-Fixed Paraffin-Embedded Tumor Tissue to Identify Single-Cell–Level PI3K Pathway Activation

Konrad H. Stopsack, Ying Huang, Svitlana Tyekucheva, Travis A. Gerke, Clyde Bango, Habiba Elfandy, Michaela Bowden, Kathryn L. Penney, Thomas M. Roberts, Giovanni Parmigiani, Philip W. Kantoff, Lorelei A. Mucci, Massimo Loda

Clin Cancer Res (2020) 26 (22): 5903–5913.

https://doi.org/10.1158/1078-0432.CCR-20-2000

Published: 13 November 2020

View article titled, Multiplex Immunofluorescence in Formalin-Fixed Paraffin-Embedded Tumor Tissue to Identify Single-Cell–Level PI3K Pathway Activation

Includes: Supplementary data

Journal Articles

Oncogenic Genomic Alterations, Clinical Phenotypes, and Outcomes in Metastatic Castration-Sensitive Prostate Cancer

Konrad H. Stopsack, Subhiksha Nandakumar, Andreas G. Wibmer, Samuel Haywood, Emily S. Weg, Ethan S. Barnett, Chloe J. Kim, Emily A. Carbone, Samantha E. Vasselman, Bastien Nguyen, Melanie A. Hullings, Howard I. Scher, Michael J. Morris, David B. Solit, Nikolaus Schultz, Philip W. Kantoff, Wassim Abida

Clin Cancer Res (2020) 26 (13): 3230–3238.

https://doi.org/10.1158/1078-0432.CCR-20-0168

Published: 01 July 2020

View article titled, Oncogenic Genomic Alterations, Clinical Phenotypes, and Outcomes in Metastatic Castration-Sensitive Prostate Cancer

Includes: Supplementary data

Journal Articles

Significance of BRCA2 and RB1 Co-loss in Aggressive Prostate Cancer Progression

Goutam Chakraborty, Joshua Armenia, Ying Z. Mazzu, Subhiksha Nandakumar, Konrad H. Stopsack, Mohammad O. Atiq, Kazumasa Komura, Lina Jehane, Rahim Hirani, Kalyani Chadalavada, Yuki Yoshikawa, Nabeela A. Khan, Yu Chen, Wassim Abida, Lorelei A. Mucci, Gwo-Shu Mary Lee, Gouri J. Nanjangud, Philip W. Kantoff

Clin Cancer Res (2020) 26 (8): 2047–2064.

https://doi.org/10.1158/1078-0432.CCR-19-1570

Published: 15 April 2020

View article titled, Significance of BRCA2 and RB1 Co-loss in Aggressive Prostate Cancer Progression

Includes: Supplementary data

Journal Articles

Statin Use Is Associated with Lower Risk of PTEN-Null and Lethal Prostate Cancer

Clin Cancer Res (2020) 26 (5): 1086–1093.

https://doi.org/10.1158/1078-0432.CCR-19-2853

Published: 02 March 2020

View article titled, Statin Use Is Associated with Lower Risk of PTEN-Null and Lethal Prostate Cancer

Includes: Supplementary data

Journal Articles

Novel RB1-Loss Transcriptomic Signature Is Associated with Poor Clinical Outcomes across Cancer Types

William S. Chen, Mohammed Alshalalfa, Shuang G. Zhao, Yang Liu, Brandon A. Mahal, David A. Quigley, Ting Wei, Elai Davicioni, Timothy R. Rebbeck, Philip W. Kantoff, Christopher A. Maher, Karen E. Knudsen, Eric J. Small, Paul L. Nguyen, Felix Y. Feng

Clin Cancer Res (2019) 25 (14): 4290–4299.

https://doi.org/10.1158/1078-0432.CCR-19-0404

Published: 15 July 2019

View article titled, Novel RB1-Loss Transcriptomic Signature Is Associated with Poor Clinical Outcomes across Cancer Types

Includes: Supplementary data

Journal Articles

A Novel Mechanism Driving Poor-Prognosis Prostate Cancer: Overexpression of the DNA Repair Gene, Ribonucleotide Reductase Small Subunit M2 (RRM2)

Clin Cancer Res (2019) 25 (14): 4480–4492.

https://doi.org/10.1158/1078-0432.CCR-18-4046

Published: 15 July 2019

View article titled, A Novel Mechanism Driving Poor-Prognosis Prostate Cancer: Overexpression of the DNA Repair Gene, Ribonucleotide Reductase Small Subunit M2 (RRM2)

Includes: Supplementary data

Journal Articles

Neoadjuvant Enzalutamide Prior to Prostatectomy

Clin Cancer Res (2017) 23 (9): 2169–2176.

https://doi.org/10.1158/1078-0432.CCR-16-1357

Published: 30 April 2017

View article titled, Neoadjuvant Enzalutamide Prior to Prostatectomy

Includes: Supplementary data

Journal Articles

A Phase II Trial of Abiraterone Combined with Dutasteride for Men with Metastatic Castration-Resistant Prostate Cancer

Rana R. McKay, Lillian Werner, Elahe A. Mostaghel, Rosina Lis, Olga Voznesensky, Zhenwei Zhang, Brett T. Marck, Alvin M. Matsumoto, Liran Domachevsky, Katherine A. Zukotynski, Manoj Bhasin, Glenn J. Bubley, Bruce Montgomery, Philip W. Kantoff, Steven P. Balk, Mary-Ellen Taplin

Clin Cancer Res (2017) 23 (4): 935–945.

https://doi.org/10.1158/1078-0432.CCR-16-0987

Published: 14 February 2017

View article titled, A Phase II Trial of Abiraterone Combined with Dutasteride for Men with Metastatic Castration-Resistant Prostate Cancer

Includes: Supplementary data

Journal Articles

Association of AR-V7 and Prostate-Specific Antigen RNA Levels in Blood with Efficacy of Abiraterone Acetate and Enzalutamide Treatment in Men with Prostate Cancer

Fangfang Qu, Wanling Xie, Mari Nakabayashi, Haitao Zhang, Seong Ho Jeong, Xiaodong Wang, Kazumasa Komura, Christopher J. Sweeney, Oliver Sartor, Gwo-Shu Mary Lee, Philip W. Kantoff

Clin Cancer Res (2017) 23 (3): 726–734.

https://doi.org/10.1158/1078-0432.CCR-16-1070

Published: 31 January 2017

View article titled, Association of AR-V7 and Prostate-Specific Antigen RNA Levels in Blood with Efficacy of Abiraterone Acetate and Enzalutamide Treatment in Men with Prostate Cancer

Includes: Supplementary data

Journal Articles

Cabozantinib Inhibits Abiraterone's Upregulation of IGFIR Phosphorylation and Enhances Its Anti–Prostate Cancer Activity

Xiaodong Wang, Ying Huang, Amanda Christie, Michaela Bowden, Gwo-Shu Mary Lee, Philip W. Kantoff, Christopher J. Sweeney

Clin Cancer Res (2015) 21 (24): 5578–5587.

https://doi.org/10.1158/1078-0432.CCR-15-0824

Published: 14 December 2015

View article titled, Cabozantinib Inhibits Abiraterone's Upregulation of IGFIR Phosphorylation and Enhances Its Anti–Prostate Cancer Activity

Includes: Supplementary data

Journal Articles

Humoral Immune Response against Nontargeted Tumor Antigens after Treatment with Sipuleucel-T and Its Association with Improved Clinical Outcome

Debraj GuhaThakurta, Nadeem A. Sheikh, Li-Qun Fan, Harini Kandadi, T. Craig Meagher, Simon J. Hall, Philip W. Kantoff, Celestia S. Higano, Eric J. Small, Thomas A. Gardner, Kate Bailey, Tuyen Vu, Todd DeVries, James B. Whitmore, Mark W. Frohlich, James B. Trager, Charles G. Drake

Clin Cancer Res (2015) 21 (16): 3619–3630.

https://doi.org/10.1158/1078-0432.CCR-14-2334

Published: 13 August 2015

View article titled, Humoral Immune Response against Nontargeted Tumor Antigens after Treatment with Sipuleucel-T and Its Association with Improved Clinical Outcome

Includes: Supplementary data

Journal Articles

Abiraterone Treatment in Castration-Resistant Prostate Cancer Selects for Progesterone Responsive Mutant Androgen Receptors

Eddy J. Chen, Adam G. Sowalsky, Shuai Gao, Changmeng Cai, Olga Voznesensky, Rachel Schaefer, Massimo Loda, Lawrence D. True, Huihui Ye, Patricia Troncoso, Rosina L. Lis, Philip W. Kantoff, Robert B. Montgomery, Peter S. Nelson, Glenn J. Bubley, Steven P. Balk, Mary-Ellen Taplin

Clin Cancer Res (2015) 21 (6): 1273–1280.

https://doi.org/10.1158/1078-0432.CCR-14-1220

Published: 12 March 2015

View article titled, Abiraterone Treatment in Castration-Resistant Prostate Cancer Selects for Progesterone Responsive Mutant Androgen Receptors

Includes: Supplementary data

Journal Articles

Integrative Analysis of 1q23.3 Copy-Number Gain in Metastatic Urothelial Carcinoma

Clin Cancer Res (2014) 20 (7): 1873–1883.

https://doi.org/10.1158/1078-0432.CCR-13-0759

Published: 31 March 2014

View article titled, Integrative Analysis of 1q23.3 Copy-Number Gain in Metastatic Urothelial Carcinoma

Includes: Supplementary data

Journal Articles

A Single Nucleotide Polymorphism in Inflammatory Gene RNASEL Predicts Outcome after Radiation Therapy for Localized Prostate Cancer

Jonathan D. Schoenfeld, Danielle N. Margalit, Julie L. Kasperzyk, Irene M. Shui, Jennifer R. Rider, Mara M. Epstein, Allison Meisner, Stacey A. Kenfield, Neil E. Martin, Paul L. Nguyen, Philip W. Kantoff, Edward L. Giovannucci, Meir J. Stampfer, Lorelei A. Mucci

Clin Cancer Res (2013) 19 (6): 1612–1619.

https://doi.org/10.1158/1078-0432.CCR-12-2718

Published: 14 March 2013

View article titled, A Single Nucleotide Polymorphism in Inflammatory Gene RNASEL Predicts Outcome after Radiation Therapy for Localized Prostate Cancer

Includes: Supplementary data

Journal Articles

Prostate Cancer Immunotherapy

Kenneth F. May, Jr., James L. Gulley, Charles G. Drake, Glenn Dranoff, Philip W. Kantoff

Clin Cancer Res (2011) 17 (16): 5233–5238.

https://doi.org/10.1158/1078-0432.CCR-10-3402

Published: 14 August 2011

View article titled, Prostate Cancer Immunotherapy

NARROW

The Impact of PIK3R1 Mutations and Insulin–PI3K–Glycolytic Pathway Regulation in Prostate Cancer

Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors

Abiraterone Acetate Induces CREB1 Phosphorylation and Enhances the Function of the CBP-p300 Complex, Leading to Resistance in Prostate Cancer Cells

Attenuation of SRC Kinase Activity Augments PARP Inhibitor–mediated Synthetic Lethality in BRCA2-altered Prostate Tumors

Dual Blockade of c-MET and the Androgen Receptor in Metastatic Castration-resistant Prostate Cancer: A Phase I Study of Concurrent Enzalutamide and Crizotinib

Multiplex Immunofluorescence in Formalin-Fixed Paraffin-Embedded Tumor Tissue to Identify Single-Cell–Level PI3K Pathway Activation

Oncogenic Genomic Alterations, Clinical Phenotypes, and Outcomes in Metastatic Castration-Sensitive Prostate Cancer

Significance of BRCA2 and RB1 Co-loss in Aggressive Prostate Cancer Progression

Statin Use Is Associated with Lower Risk of PTEN-Null and Lethal Prostate Cancer

Novel RB1-Loss Transcriptomic Signature Is Associated with Poor Clinical Outcomes across Cancer Types

A Novel Mechanism Driving Poor-Prognosis Prostate Cancer: Overexpression of the DNA Repair Gene, Ribonucleotide Reductase Small Subunit M2 (RRM2)

Neoadjuvant Enzalutamide Prior to Prostatectomy

A Phase II Trial of Abiraterone Combined with Dutasteride for Men with Metastatic Castration-Resistant Prostate Cancer

Association of AR-V7 and Prostate-Specific Antigen RNA Levels in Blood with Efficacy of Abiraterone Acetate and Enzalutamide Treatment in Men with Prostate Cancer

Cabozantinib Inhibits Abiraterone's Upregulation of IGFIR Phosphorylation and Enhances Its Anti–Prostate Cancer Activity

Humoral Immune Response against Nontargeted Tumor Antigens after Treatment with Sipuleucel-T and Its Association with Improved Clinical Outcome

Abiraterone Treatment in Castration-Resistant Prostate Cancer Selects for Progesterone Responsive Mutant Androgen Receptors

Integrative Analysis of 1q23.3 Copy-Number Gain in Metastatic Urothelial Carcinoma

A Single Nucleotide Polymorphism in Inflammatory Gene RNASEL Predicts Outcome after Radiation Therapy for Localized Prostate Cancer

Prostate Cancer Immunotherapy

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