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Philip Quirke
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Journal Articles

Associations between AI-Assisted Tumor Amphiregulin and Epiregulin IHC and Outcomes from Anti-EGFR Therapy in the Routine Management of Metastatic Colorectal Cancer

Christopher J.M. Williams, Faye Elliott, Nancy Sapanara, Faranak Aghaei, Liping Zhang, Andrea Muranyi, Dongyao Yan, Isaac Bai, Zuo Zhao, Michael Shires, Henry M. Wood, Susan D. Richman, Gemma Hemmings, Michael Hale, Daniel Bottomley, Leanne Galvin, Caroline Cartlidge, Sarah Dance, Chris M. Bacon, Laura Mansfield, Kathe Young-Zvandasara, Ajay Sudan, Katy Lambert, Irena Bibby, Sarah E. Coupland, Amir Montazeri, Natalie Kipling, Kathryn Hughes, Simon S. Cross, Alice Dewdney, Leanne Pheasey, Cathryn Leng, Tatenda Gochera, D. Chas Mangham, Mark Saunders, Martin Pritchard, Helen Stott, Abhik Mukherjee, Mohammad Ilyas, Rafael Silverman, Georgina Hyland, Declan Sculthorpe, Kirsty Thornton, Imogen Gould, Ann O'Callaghan, Nicholas Brown, Samantha Turnbull, Lisa Shaw, Matthew T. Seymour, Nicholas P. West, Jenny F. Seligmann, Shalini Singh, Kandavel Shanmugam, Philip Quirke
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (20): 4153–4165.
https://doi.org/10.1158/1078-0432.CCR-23-0859
Published: 13 October 2023
View article titled, Associations between AI-Assisted Tumor Amphiregulin and Epiregulin IHC and Outcomes from Anti-EGFR Therapy in the Routine Management of Metastatic Colorectal Cancer
Open the PDF for Associations between AI-Assisted Tumor Amphiregulin and Epiregulin IHC and Outcomes from Anti-EGFR Therapy in the Routine Management of Metastatic Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Artificial Intelligence–Assisted Amphiregulin and Epiregulin IHC Predicts Panitumumab Benefit in RAS Wild-Type Metastatic Colorectal Cancer

Christopher J.M. Williams, Jenny F. Seligmann, Faye Elliott, Michael Shires, Susan D. Richman, Sarah Brown, Liping Zhang, Shalini Singh, Judith Pugh, Xiao-Meng Xu, Andrea Muranyi, Christoph Guetter, Auranuch Lorsakul, Uday Kurkure, Zuo Zhao, Jim Martin, Xingwei Wang, Kien Nguyen, Wen-Wei Liu, Dongyao Yan, Nicholas P. West, Jennifer H. Barrett, Michael Barnes, Isaac Bai, Matthew T. Seymour, Philip Quirke, Kandavel Shanmugam
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (12): 3422–3431.
https://doi.org/10.1158/1078-0432.CCR-21-0120
Published: 15 June 2021
View article titled, Artificial Intelligence–Assisted Amphiregulin and Epiregulin IHC Predicts Panitumumab Benefit in <em>RAS</em> Wild-Type Metastatic Colorectal Cancer
Open the PDF for Artificial Intelligence–Assisted Amphiregulin and Epiregulin IHC Predicts Panitumumab Benefit in <em>RAS</em> Wild-Type Metastatic Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Microbiome Analysis of More Than 2,000 NHS Bowel Cancer Screening Programme Samples Shows the Potential to Improve Screening Accuracy

Caroline Young, Henry M. Wood, Alba Fuentes Balaguer, Daniel Bottomley, Niall Gallop, Lyndsay Wilkinson, Sally C. Benton, Martin Brealey, Cerin John, Carole Burtonwood, Kelsey N. Thompson, Yan Yan, Jennifer H. Barrett, Eva J.A. Morris, Curtis Huttenhower, Philip Quirke
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8): 2246–2254.
https://doi.org/10.1158/1078-0432.CCR-20-3807
Published: 15 April 2021
View article titled, Microbiome Analysis of More Than 2,000 NHS Bowel Cancer Screening Programme Samples Shows the Potential to Improve Screening Accuracy
Open the PDF for Microbiome Analysis of More Than 2,000 NHS Bowel Cancer Screening Programme Samples Shows the Potential to Improve Screening Accuracy in another window
Includes: Supplementary data
Journal Articles

In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer

Sudhir B. Malla, David J. Fisher, Enric Domingo, Andrew Blake, Sylvana Hassanieh, Keara L. Redmond, Susan D. Richman, Michael Youdell, Steven M. Walker, Gemma E. Logan, Aikaterina Chatzipli, Raheleh Amirkhah, Matthew P. Humphries, Stephanie G. Craig, Ultan McDermott, Matthew T. Seymour, Dion G. Morton, Philip Quirke, Nicholas P. West, Manuel Salto-Tellez, Richard D. Kennedy, Patrick G. Johnston, Ian Tomlinson, Viktor H. Koelzer, Letitia Campo, Richard S. Kaplan, Daniel B. Longley, Mark Lawler, Timothy S. Maughan, Louise C. Brown, Philip D. Dunne
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (1): 288–300.
https://doi.org/10.1158/1078-0432.CCR-20-3237
Published: 04 January 2021
View article titled, In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies

Sabine Venderbosch, Iris D. Nagtegaal, Tim S. Maughan, Christopher G. Smith, Jeremy P. Cheadle, David Fisher, Richard Kaplan, Philip Quirke, Matthew T. Seymour, Susan D. Richman, Gerrit A. Meijer, Bauke Ylstra, Danielle A.M. Heideman, Anton F.J. de Haan, Cornelis J.A. Punt, Miriam Koopman
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (20): 5322–5330.
https://doi.org/10.1158/1078-0432.CCR-14-0332
Published: 14 October 2014
View article titled, Mismatch Repair Status and <em>BRAF</em> Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies
Open the PDF for Mismatch Repair Status and <em>BRAF</em> Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies in another window
Includes: Supplementary data
Journal Articles

Chromosome 5q Loss in Colorectal Flat Adenomas

Quirinus J.M. Voorham, Beatriz Carvalho, Angela J. Spiertz, Nicole C.T. van Grieken, Sandra Mongera, Eveline J.A. Rondagh, Mark A. van de Wiel, Ekaterina S. Jordanova, Bauke Ylstra, Martin Kliment, Heike Grabsch, Bjorn J. Rembacken, Tomio Arai, Adriaan P. de Bruïne, Silvia Sanduleanu, Philip Quirke, Chris J.J. Mulder, Manon van Engeland, Gerrit A. Meijer
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (17): 4560–4569.
https://doi.org/10.1158/1078-0432.CCR-11-2385
Published: 30 August 2012
View article titled, Chromosome 5q Loss in Colorectal Flat Adenomas
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Includes: Supplementary data