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Philip J. Tofilon
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Journal Articles

The ATP-Competitive mTOR Inhibitor INK128 Enhances In Vitro and In Vivo Radiosensitivity of Pancreatic Carcinoma Cells

Thomas J. Hayman, Amy Wahba, Barbara H. Rath, Heekyong Bae, Tamalee Kramp, Uma T. Shankavaram, Kevin Camphausen, Philip J. Tofilon
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (1): 110–119.
https://doi.org/10.1158/1078-0432.CCR-13-2136
Published: 05 January 2014
View article titled, The ATP-Competitive mTOR Inhibitor INK128 Enhances <em>In Vitro</em> and <em>In Vivo</em> Radiosensitivity of Pancreatic Carcinoma Cells
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Includes: Supplementary data
Journal Articles

Microenvironmental Regulation of Glioblastoma Radioresponse

Muhammad Jamal, Barbara H. Rath, Eli S. Williams, Kevin Camphausen, Philip J. Tofilon
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (24): 6049–6059.
https://doi.org/10.1158/1078-0432.CCR-10-2435
Published: 16 December 2010
View article titled, Microenvironmental Regulation of Glioblastoma Radioresponse
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Includes: Supplementary data
Journal Articles

CD133+ Glioblastoma Stem-like Cells are Radiosensitive with a Defective DNA Damage Response Compared with Established Cell Lines

Amy M. McCord, Muhammad Jamal, Eli S. Williams, Kevin Camphausen, Philip J. Tofilon
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (16): 5145–5153.
https://doi.org/10.1158/1078-0432.CCR-09-0263
Published: 12 August 2009
View article titled, CD133<sup>+</sup> Glioblastoma Stem-like Cells are Radiosensitive with a Defective DNA Damage Response Compared with Established Cell Lines
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Journal Articles

Urine Analysis and Protein Networking Identify Met as a Marker of Metastatic Prostate Cancer

Andrea L. Russo, Kimberly Jedlicka, Meredith Wernick, Debbie McNally, Melissa Kirk, Mary Sproull, Sharon Smith, Uma Shankavaram, Aradhana Kaushal, William D. Figg, William Dahut, Deborah Citrin, Donald P. Bottaro, Paul S. Albert, Philip J. Tofilon, Kevin Camphausen
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (13): 4292–4298.
https://doi.org/10.1158/1078-0432.CCR-09-0599
Published: 01 July 2009
View article titled, Urine Analysis and Protein Networking Identify Met as a Marker of Metastatic Prostate Cancer
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Journal Articles

In vitro and In vivo Radiosensitization of Glioblastoma Cells by the Poly (ADP-Ribose) Polymerase Inhibitor E7016

Andrea L. Russo, Hyuk-Chan Kwon, William E. Burgan, Donna Carter, Katie Beam, Xu Weizheng, Jie Zhang, Barbara S. Slusher, Arnab Chakravarti, Philip J. Tofilon, Kevin Camphausen
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (2): 607–612.
https://doi.org/10.1158/1078-0432.CCR-08-2079
Published: 15 January 2009
View article titled, <em>In vitro</em> and <em>In vivo</em> Radiosensitization of Glioblastoma Cells by the Poly (ADP-Ribose) Polymerase Inhibitor E7016
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Journal Articles

Postradiation Sensitization of the Histone Deacetylase Inhibitor Valproic Acid

Prakash Chinnaiyan, David Cerna, William E. Burgan, Katie Beam, Eli S. Williams, Kevin Camphausen, Philip J. Tofilon
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (17): 5410–5415.
https://doi.org/10.1158/1078-0432.CCR-08-0643
Published: 02 September 2008
View article titled, Postradiation Sensitization of the Histone Deacetylase Inhibitor Valproic Acid
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Journal Articles

In vitro and In vivo Radiosensitization Induced by the DNA Methylating Agent Temozolomide

Whoon Jong Kil, David Cerna, William E. Burgan, Katie Beam, Donna Carter, Patricia S. Steeg, Philip J. Tofilon, Kevin Camphausen
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (3): 931–938.
https://doi.org/10.1158/1078-0432.CCR-07-1856
Published: 01 February 2008
View article titled, <em>In vitro</em> and <em>In vivo</em> Radiosensitization Induced by the DNA Methylating Agent Temozolomide
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Journal Articles

Inhibition of Hsp90: A Multitarget Approach to Radiosensitization

Kevin Camphausen, Philip J. Tofilon
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (15): 4326–4330.
https://doi.org/10.1158/1078-0432.CCR-07-0632
Published: 01 August 2007
View article titled, Inhibition of Hsp90: A Multitarget Approach to Radiosensitization
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Journal Articles

In vitro and In vivo Radiosensitization Induced by the Ribonucleotide Reductase Inhibitor Triapine (3-Aminopyridine-2-Carboxaldehyde-Thiosemicarbazone)

Christopher A. Barker, William E. Burgan, Donna J. Carter, David Cerna, David Gius, Melinda G. Hollingshead, Kevin Camphausen, Philip J. Tofilon
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (9): 2912–2918.
https://doi.org/10.1158/1078-0432.CCR-05-2860
Published: 04 May 2006
View article titled, <em>In vitro</em> and <em>In vivo</em> Radiosensitization Induced by the Ribonucleotide Reductase Inhibitor Triapine (3-Aminopyridine-2-Carboxaldehyde-Thiosemicarbazone)
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Journal Articles

Enhancement of In vitro and In vivo Tumor Cell Radiosensitivity by the DNA Methylation Inhibitor Zebularine

Hideaki Dote, David Cerna, William E. Burgan, Donna J. Carter, Michael A. Cerra, Melinda G. Hollingshead, Kevin Camphausen, Philip J. Tofilon
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (12): 4571–4579.
https://doi.org/10.1158/1078-0432.CCR-05-0050
Published: 15 June 2005
View article titled, Enhancement of <em>In vitro</em> and <em>In vivo</em> Tumor Cell Radiosensitivity by the DNA Methylation Inhibitor Zebularine
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Journal Articles

Enhanced Tumor Cell Radiosensitivity and Abrogation of G2 and S Phase Arrest by the Hsp90 Inhibitor 17-(Dimethylaminoethylamino)-17-demethoxygeldanamycin

Elizabeth E. A. Bull, Hideaki Dote, Kristin J. Brady, William E. Burgan, Donna J. Carter, Michael A. Cerra, Kelli A. Oswald, Melinda G. Hollingshead, Kevin Camphausen, Philip J. Tofilon
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (23): 8077–8084.
https://doi.org/10.1158/1078-0432.CCR-04-1212
Published: 07 December 2004
View article titled, Enhanced Tumor Cell Radiosensitivity and Abrogation of G<sub>2</sub> and S Phase Arrest by the Hsp90 Inhibitor 17-(Dimethylaminoethylamino)-17-demethoxygeldanamycin
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Journal Articles

Enhancement of Xenograft Tumor Radiosensitivity by the Histone Deacetylase Inhibitor MS-275 and Correlation with Histone Hyperacetylation

Kevin Camphausen, Tamalee Scott, Mary Sproull, Philip J. Tofilon
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (18): 6066–6071.
https://doi.org/10.1158/1078-0432.CCR-04-0537
Published: 24 September 2004
View article titled, Enhancement of Xenograft Tumor Radiosensitivity by the Histone Deacetylase Inhibitor MS-275 and Correlation with Histone Hyperacetylation
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Journal Articles

Effect of Radiation and Ibuprofen on Normoxic Renal Carcinoma Cells Overexpressing Hypoxia-Inducible Factors by Loss of von Hippel–Lindau Tumor Suppressor Gene Function

Sanjeewani T. Palayoor, Melissa A. Burgos, Azadeh Shoaibi, Philip J. Tofilon, C. Norman Coleman
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (12): 4158–4164.
https://doi.org/10.1158/1078-0432.CCR-04-0005
Published: 24 June 2004
View article titled, Effect of Radiation and Ibuprofen on Normoxic Renal Carcinoma Cells Overexpressing Hypoxia-Inducible Factors by Loss of von Hippel–Lindau Tumor Suppressor Gene Function
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Journal Articles

Molecular Targets for Radiation Therapy: Bringing Preclinical Data into Clinical Trials

Philip J. Tofilon, Scott Saxman, C. Norman Coleman
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (10): 3518–3520.
Published: 23 September 2003
View article titled, Molecular Targets for Radiation Therapy: <subtitle>Bringing Preclinical Data into Clinical Trials</subtitle>
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Journal Articles

Enhanced Cell Killing Induced by the Combination of Radiation and the Heat Shock Protein 90 Inhibitor 17-Allylamino-17- Demethoxygeldanamycin: A Multitarget Approach to Radiosensitization

Jeffery S. Russell, William Burgan, Kelli A. Oswald, Kevin Camphausen, Philip J. Tofilon
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (10): 3749–3755.
Published: 23 September 2003
View article titled, Enhanced Cell Killing Induced by the Combination of Radiation and the Heat Shock Protein 90 Inhibitor 17-Allylamino-17- Demethoxygeldanamycin: <subtitle>A Multitarget Approach to Radiosensitization</subtitle>
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Journal Articles

Ibuprofen-mediated Reduction of Hypoxia-inducible Factors HIF-1α and HIF-2α in Prostate Cancer Cells

Sanjeewani T. Palayoor, Philip J. Tofilon, C. Norman Coleman
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (8): 3150–3157.
Published: 11 August 2003
View article titled, Ibuprofen-mediated Reduction of Hypoxia-inducible Factors HIF-1α and HIF-2α in Prostate Cancer Cells
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Journal Articles

Enhancement of Intrinsic Tumor Cell Radiosensitivity Induced by a Selective Cyclooxygenase-2 Inhibitor

Cordula Petersen, Sven Petersen, Luka Milas, Frederick F. Lang, Philip J. Tofilon
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (6): 2513–2520.
Published: 01 June 2000
View article titled, Enhancement of Intrinsic Tumor Cell Radiosensitivity Induced by a Selective Cyclooxygenase-2 Inhibitor
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