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Peter de Bruijn
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Journal Articles

Intratumoral Comparison of Nanoparticle Entrapped Docetaxel (CPC634) with Conventional Docetaxel in Patients with Solid Tumors

Florence Atrafi, Ruben A.G. van Eerden, Marte A.M van Hylckama Vlieg, Esther Oomen-de Hoop, Peter de Bruijn, Martijn P. Lolkema, Adriaan Moelker, Cristianne J. Rijcken, Rob Hanssen, Alex Sparreboom, Ferry A.L.M. Eskens, Ron H.J. Mathijssen, Stijn L.W. Koolen
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (14): 3537–3545.
https://doi.org/10.1158/1078-0432.CCR-20-0008
Published: 15 July 2020
View article titled, Intratumoral Comparison of Nanoparticle Entrapped Docetaxel (CPC634) with Conventional Docetaxel in Patients with Solid Tumors
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Includes: Supplementary data
Journal Articles

Influence of Enzalutamide on Cabazitaxel Pharmacokinetics: a Drug–Drug Interaction Study in Metastatic Castration-resistant Prostate Cancer (mCRPC) Patients

Bodine P.S. Belderbos, Sander Bins, Roelof W.F. van Leeuwen, Esther Oomen-de Hoop, Nelly van der Meer, Peter de Bruijn, Paul Hamberg, Esther N.M. Overkleeft, Wendy M. van der Deure, Martijn P. Lolkema, Ronald de Wit, Ron H.J. Mathijssen
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (3): 541–546.
https://doi.org/10.1158/1078-0432.CCR-17-2336
Published: 31 January 2018
View article titled, Influence of Enzalutamide on Cabazitaxel Pharmacokinetics: a Drug–Drug Interaction Study in Metastatic Castration-resistant Prostate Cancer (mCRPC) Patients
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Journal Articles

Phase I Study of RGB-286638, A Novel, Multitargeted Cyclin-Dependent Kinase Inhibitor in Patients with Solid Tumors

Diane A.J. van der Biessen, Herman Burger, Peter de Bruijn, Cor H.J. Lamers, Nicole Naus, Hannes Loferer, Erik A.C. Wiemer, Ron H.J. Mathijssen, Maja J.A. de Jonge
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (18): 4776–4783.
https://doi.org/10.1158/1078-0432.CCR-14-0325
Published: 14 September 2014
View article titled, Phase I Study of RGB-286638, A Novel, Multitargeted Cyclin-Dependent Kinase Inhibitor in Patients with Solid Tumors
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Includes: Supplementary data
Journal Articles

Abstract A55: Influence of ABCB1 polymorphisms on paclitaxel pharmacokinetics in ovarian cancer patients

Bo Gao, Annemieke J.M. Nieuweboer, Hongmei Xu, Jonathan Beesley, Inge M. Ghobadi Moghaddam-Helmantel, Anne-Joy M. de Graan, Peter de Bruijn, Howard Gurney, Sharon E. Johnatty, Philip Beale, Georgia Chenevix-Trench, Rosemary L. Balleine, Ron H.J. Ron H.J. Mathijssen, Paul R. Harnett
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (19_Supplement): A55.
https://doi.org/10.1158/1078-0432.OVCA13-A55
Published: 13 May 2014
View article titled, Abstract A55: Influence of ABCB1 polymorphisms on paclitaxel pharmacokinetics in ovarian cancer patients
Journal Articles

CYP3A4*22 Genotype and Systemic Exposure Affect Paclitaxel-Induced Neurotoxicity

Anne-Joy M. de Graan, Laure Elens, Jason A. Sprowl, Alex Sparreboom, Lena E. Friberg, Bronno van der Holt, Pleun J. de Raaf, Peter de Bruijn, Frederike K. Engels, Ferry A.L.M. Eskens, Erik A.C. Wiemer, Jaap Verweij, Ron H.J. Mathijssen, Ron H.N. van Schaik
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (12): 3316–3324.
https://doi.org/10.1158/1078-0432.CCR-12-3786
Published: 13 June 2013
View article titled, <em>CYP3A4*22</em> Genotype and Systemic Exposure Affect Paclitaxel-Induced Neurotoxicity
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Includes: Supplementary data
Journal Articles

Long-term Prospective Population PK Study in GIST Patients—Response

Ron H.J. Mathijssen, Peter de Bruijn, Karel Eechoute, Alex Sparreboom
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (4): 950.
https://doi.org/10.1158/1078-0432.CCR-12-3807
Published: 14 February 2013
View article titled, Long-term Prospective Population PK Study in GIST Patients—Response
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Journal Articles

Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel

Anne-Joy M. de Graan, Cynthia S. Lancaster, Amanda Obaidat, Bruno Hagenbuch, Laure Elens, Lena E. Friberg, Peter de Bruijn, Shuiying Hu, Alice A. Gibson, Gitte H. Bruun, Thomas J. Corydon, Torben S. Mikkelsen, Aisha L. Walker, Guoqing Du, Walter J. Loos, Ron H. N. van Schaik, Sharyn D. Baker, Ron H. J. Mathijssen, Alex Sparreboom
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (16): 4433–4440.
https://doi.org/10.1158/1078-0432.CCR-12-0761
Published: 14 August 2012
View article titled, Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel
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Includes: Supplementary data
Journal Articles

Therapeutic Drug Monitoring for the Individualization of Docetaxel Dosing: A Randomized Pharmacokinetic Study

Frederike K. Engels, Walter J. Loos, Jessica M. van der Bol, Peter de Bruijn, Ron H.J. Mathijssen, Jaap Verweij, Ron A.A. Mathot
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (2): 353–362.
https://doi.org/10.1158/1078-0432.CCR-10-1636
Published: 16 January 2011
View article titled, Therapeutic Drug Monitoring for the Individualization of Docetaxel Dosing: A Randomized Pharmacokinetic Study
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Journal Articles

Phase I and Pharmacokinetic Study of the Polyamine Synthesis Inhibitor SAM486A in Combination with 5-Fluorouracil/ Leucovorin in Metastatic Colorectal Cancer

Lia van Zuylen, John Bridgewater, Alex Sparreboom, Ferry A. L. M. Eskens, Peter de Bruijn, Ivo Sklenar, Andre S. T. Planting, Les Choi, Douglas Bootle, Christian Mueller, Jonathan A. Ledermann, Jaap Verweij
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (6): 1949–1955.
https://doi.org/10.1158/1078-0432.CCR-02-0995
Published: 24 March 2004
View article titled, Phase I and Pharmacokinetic Study of the Polyamine Synthesis Inhibitor SAM486A in Combination with 5-Fluorouracil/ Leucovorin in Metastatic Colorectal Cancer
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Journal Articles

Structural Identification and Biological Activity of 7-Methyl-10,11-Ethylenedioxy-20( S )-Camptothecin, a Photodegradant of Lurtotecan

Walter J. Loos, Jaap Verweij, Diederik F. S. Kehrer, Peter de Bruijn, Franciscus M. H. de Groot, Marta Hamilton, Kees Nooter, Gerrit Stoter, Alex Sparreboom
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (3): 856–862.
Published: 01 March 2002
View article titled, Structural Identification and Biological Activity of 7-Methyl-10,11-Ethylenedioxy-20( <em>S</em> )-Camptothecin, a Photodegradant of Lurtotecan
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Journal Articles

Modulation of Irinotecan-induced Diarrhea by Cotreatment with Neomycin in Cancer Patients

Diederik F. S. Kehrer, Alex Sparreboom, Jaap Verweij, Peter de Bruijn, Corine A. Nierop, Jacqueline van de Schraaf, Elisabeth J. Ruijgrok, Maja J. A. de Jonge
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (5): 1136–1141.
Published: 01 May 2001
View article titled, Modulation of Irinotecan-induced Diarrhea by Cotreatment with Neomycin in Cancer Patients
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Journal Articles

Factors Involved in Prolongation of the Terminal Disposition Phase of SN-38: Clinical and Experimental Studies

Diederik F. S. Kehrer, Wataru Yamamoto, Jaap Verweij, Maja J. A. de Jonge, Peter de Bruijn, Alex Sparreboom
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (9): 3451–3458.
Published: 01 September 2000
View article titled, Factors Involved in Prolongation of the Terminal Disposition Phase of SN-38: Clinical and Experimental Studies
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Journal Articles

Drug-Administration Sequence Does Not Change Pharmacodynamics and Kinetics of Irinotecan and Cisplatin

Maja J. A. de Jonge, Jaap Verweij, André S. T. Planting, Maria E. L. van der Burg, Gerrit Stoter, Maureen M. de Boer-Dennert, Peter de Bruijn, Eric Brouwer, Laurent Vernillet, Alex Sparreboom
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (8): 2012–2017.
Published: 01 August 1999
View article titled, Drug-Administration Sequence Does Not Change Pharmacodynamics and Kinetics of Irinotecan and Cisplatin
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