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Peter Olson
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Journal Articles

Impact of co-mutations and transcriptional signatures in non-small cell lung cancer patients treated with adagrasib in the KRYSTAL-1 trial

Marcelo V. Negrao, Alvaro G. Paula, David Molkentine, Laura Hover, Monique Nilsson, Natalie Vokes, Lars Engstrom, Andrew Calinisan, David M. Briere, Laura Waters, Jill Hallin, Lixia Diao, Mehmet Altan, George R. Blumenschein, Ferdinandos Skoulidis, Jing Wang, Scott E. Kopetz, David S. Hong, Don L. Gibbons, Peter Olson, James G. Christensen, John V. Heymach
Journal: Clinical Cancer Research
Clin Cancer Res (2025)
https://doi.org/10.1158/1078-0432.CCR-24-2310
Published: 13 January 2025
View article titled, Impact of co-mutations and transcriptional signatures in non-small cell lung cancer patients treated with adagrasib in the KRYSTAL-1 trial
Open the PDF for Impact of co-mutations and transcriptional signatures in non-small cell lung cancer patients treated with adagrasib in the KRYSTAL-1 trial in another window
Includes: Supplementary data
Journal Articles

Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non–Small Cell Lung Cancer

Joshua K. Sabari, Vamsidhar Velcheti, Kazuhide Shimizu, Matthew R. Strickland, Rebecca S. Heist, Mohini Singh, Naema Nayyar, Anita Giobbie-Hurder, Subba R. Digumarthy, Justin F. Gainor, Anant P. Rajan, Edwin Nieblas-Bedolla, Aaron C. Burns, Jill Hallin, Peter Olson, James G. Christensen, Sylvia C. Kurz, Priscilla K. Brastianos, Hiroaki Wakimoto
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (15): 3318–3328.
https://doi.org/10.1158/1078-0432.CCR-22-0383
Published: 02 August 2022
View article titled, Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRAS<sup>G12C</sup>-Mutant Non–Small Cell Lung Cancer
Open the PDF for Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRAS<sup>G12C</sup>-Mutant Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring MET Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors in Nonclinical Models

Lars D. Engstrom, Ruth Aranda, Matthew Lee, Elizabeth A. Tovar, Curt J. Essenburg, Zachary Madaj, Harrah Chiang, David Briere, Jill Hallin, Pedro P. Lopez-Casas, Natalia Baños, Camino Menendez, Manuel Hidalgo, Vanessa Tassell, Richard Chao, Darya I. Chudova, Richard B. Lanman, Peter Olson, Lyudmilla Bazhenova, Sandip Pravin Patel, Carrie Graveel, Mizuki Nishino, Geoffrey I. Shapiro, Nir Peled, Mark M. Awad, Pasi A. Jänne, James G. Christensen
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (21): 6661–6672.
https://doi.org/10.1158/1078-0432.CCR-17-1192
Published: 31 October 2017
View article titled, Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring <em>MET</em> Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors in Nonclinical Models
Open the PDF for Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring <em>MET</em> Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors in Nonclinical Models in another window
Includes: Supplementary data
Journal Articles

Abstract A36: Assessment of effectiveness and molecular markers of CDK4/6 inhibitor Palbociclib in Pancreatic Ductal Adenocarcinomas

Beatriz Salvador, Pedro P. López-Casas, Camino Menéndez, Natalia Baños, Francesca Sarno, Yin Min-Jean, Peter Olson, Todd VanArsdale, David J. Shields, Manuel Hidalgo
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): A36.
https://doi.org/10.1158/1557-3265.PDX16-A36
Published: 15 August 2016
View article titled, Abstract A36: Assessment of effectiveness and molecular markers of CDK4/6 inhibitor Palbociclib in Pancreatic Ductal Adenocarcinomas
Journal Articles

PEST Domain Mutations in Notch Receptors Comprise an Oncogenic Driver Segment in Triple-Negative Breast Cancer Sensitive to a γ-Secretase Inhibitor

Kai Wang, Qin Zhang, Danan Li, Keith Ching, Cathy Zhang, Xianxian Zheng, Mark Ozeck, Stephanie Shi, Xiaorong Li, Hui Wang, Paul Rejto, James Christensen, Peter Olson
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (6): 1487–1496.
https://doi.org/10.1158/1078-0432.CCR-14-1348
Published: 12 March 2015
View article titled, PEST Domain Mutations in Notch Receptors Comprise an Oncogenic Driver Segment in Triple-Negative Breast Cancer Sensitive to a γ-Secretase Inhibitor
Open the PDF for PEST Domain Mutations in Notch Receptors Comprise an Oncogenic Driver Segment in Triple-Negative Breast Cancer Sensitive to a γ-Secretase Inhibitor in another window
Includes: Supplementary data