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Pedro R. Lowenstein
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Journal Articles

Zinc Finger MYND-Type Containing 8 (ZMYND8) Is Epigenetically Regulated in Mutant Isocitrate Dehydrogenase 1 (IDH1) Glioma to Promote Radioresistance

Stephen V. Carney, Kaushik Banerjee, Anzar Mujeeb, Brandon Zhu, Santiago Haase, Maria L. Varela, Padma Kadiyala, Claire E. Tronrud, Ziwen Zhu, Devarshi Mukherji, Preethi Gorla, Yilun Sun, Rebecca Tagett, Felipe J. Núñez, Maowu Luo, Weibo Luo, Mats Ljungman, Yayuan Liu, Ziyun Xia, Anna Schwendeman, Tingting Qin, Maureen A. Sartor, Joseph F. Costello, Daniel P. Cahill, Pedro R. Lowenstein, Maria G. Castro
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (9): 1763–1782.
https://doi.org/10.1158/1078-0432.CCR-22-1896
Published: 01 May 2023
View article titled, Zinc Finger MYND-Type Containing 8 (ZMYND8) Is Epigenetically Regulated in Mutant Isocitrate Dehydrogenase 1 (IDH1) Glioma to Promote Radioresistance
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Includes: Supplementary data
Journal Articles

Synthetic High-density Lipoprotein Nanodiscs for Personalized Immunotherapy Against Gliomas

Lindsay Scheetz, Padma Kadiyala, Xiaoqi Sun, Sejin Son, Alireza Hassani Najafabadi, Marisa Aikins, Pedro R. Lowenstein, Anna Schwendeman, Maria G. Castro, James J. Moon
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (16): 4369–4380.
https://doi.org/10.1158/1078-0432.CCR-20-0341
Published: 14 August 2020
View article titled, Synthetic High-density Lipoprotein Nanodiscs for Personalized Immunotherapy Against Gliomas
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Includes: Supplementary data
Journal Articles

Therapeutic Efficacy of Immune Stimulatory Thymidine Kinase and fms-like Tyrosine Kinase 3 Ligand (TK/Flt3L) Gene Therapy in a Mouse Model of High-Grade Brainstem Glioma

Flor Mendez, Padma Kadiyala, Felipe J. Nunez, Stephen Carney, Fernando M. Nunez, Jessica C. Gauss, Ramya Ravindran, Sheeba Pawar, Marta Edwards, Maria Belen Garcia-Fabiani, Santiago Haase, Pedro R. Lowenstein, Maria G. Castro
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (15): 4080–4092.
https://doi.org/10.1158/1078-0432.CCR-19-3714
Published: 03 August 2020
View article titled, Therapeutic Efficacy of Immune Stimulatory Thymidine Kinase and fms-like Tyrosine Kinase 3 Ligand (TK/Flt3L) Gene Therapy in a Mouse Model of High-Grade Brainstem Glioma
Open the PDF for Therapeutic Efficacy of Immune Stimulatory Thymidine Kinase and fms-like Tyrosine Kinase 3 Ligand (TK/Flt3L) Gene Therapy in a Mouse Model of High-Grade Brainstem Glioma in another window
Includes: Supplementary data
Journal Articles

Multiple Expressed Endogenous Glioma Epitopes as Novel Vaccines for Gliomas

Pedro R. Lowenstein, Maria G. Castro
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (19): 4760–4762.
https://doi.org/10.1158/1078-0432.CCR-16-1477
Published: 02 October 2016
View article titled, Multiple Expressed Endogenous Glioma Epitopes as Novel Vaccines for Gliomas
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Journal Articles

Blocking Immunosuppressive Checkpoints for Glioma Therapy: The More the Merrier!

Maria G. Castro, Gregory J. Baker, Pedro R. Lowenstein
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (20): 5147–5149.
https://doi.org/10.1158/1078-0432.CCR-14-0820
Published: 14 October 2014
View article titled, Blocking Immunosuppressive Checkpoints for Glioma Therapy: The More the Merrier!
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Journal Articles

Temozolomide Does Not Impair Gene Therapy-Mediated Antitumor Immunity in Syngeneic Brain Tumor Models

Marianela Candolfi, Kader Yagiz, Mia Wibowo, Gabrielle E. Ahlzadeh, Mariana Puntel, Homayon Ghiasi, Neha Kamran, Christopher Paran, Pedro R. Lowenstein, Maria G. Castro
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (6): 1555–1565.
https://doi.org/10.1158/1078-0432.CCR-13-2140
Published: 13 March 2014
View article titled, Temozolomide Does Not Impair Gene Therapy-Mediated Antitumor Immunity in Syngeneic Brain Tumor Models
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Includes: Supplementary data
Journal Articles

Engineering the Brain Tumor Microenvironment Enhances the Efficacy of Dendritic Cell Vaccination: Implications for Clinical Trial Design

Yohei Mineharu, Gwendalyn D. King, AKM G. Muhammad, Serguei Bannykh, Kurt M. Kroeger, Chunyan Liu, Pedro R. Lowenstein, Maria G. Castro
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (14): 4705–4718.
https://doi.org/10.1158/1078-0432.CCR-11-0915
Published: 17 July 2011
View article titled, Engineering the Brain Tumor Microenvironment Enhances the Efficacy of Dendritic Cell Vaccination: Implications for Clinical Trial Design
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Includes: Supplementary data
Journal Articles

Antiglioma Immunological Memory in Response to Conditional Cytotoxic/Immune-Stimulatory Gene Therapy: Humoral and Cellular Immunity Lead to Tumor Regression

A.K.M. Ghulam Muhammad, Marianela Candolfi, Gwendalyn D. King, Kader Yagiz, David Foulad, Yohei Mineharu, Kurt M. Kroeger, Katherine A. Treuer, W. Stephen Nichols, Nicholas S. Sanderson, Jieping Yang, Maksim Khayznikov, Nico Van Rooijen, Pedro R. Lowenstein, Maria G. Castro
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (19): 6113–6127.
https://doi.org/10.1158/1078-0432.CCR-09-1087
Published: 30 September 2009
View article titled, Antiglioma Immunological Memory in Response to Conditional Cytotoxic/Immune-Stimulatory Gene Therapy: Humoral and Cellular Immunity Lead to Tumor Regression
Open the PDF for Antiglioma Immunological Memory in Response to Conditional Cytotoxic/Immune-Stimulatory Gene Therapy: Humoral and Cellular Immunity Lead to Tumor Regression in another window
Includes: Supplementary data
Journal Articles

Release of HMGB1 in Response to Proapoptotic Glioma Killing Strategies: Efficacy and Neurotoxicity

Marianela Candolfi, Kader Yagiz, David Foulad, Gabrielle E. Alzadeh, Matthew Tesarfreund, A.K.M. Ghulam Muhammad, Mariana Puntel, Kurt M. Kroeger, Chunyan Liu, Sharon Lee, James F. Curtin, Gwendalyn D. King, Jonathan Lerner, Katsuaki Sato, Yohei Mineharu, Weidong Xiong, Pedro R. Lowenstein, Maria G. Castro
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (13): 4401–4414.
https://doi.org/10.1158/1078-0432.CCR-09-0155
Published: 01 July 2009
View article titled, Release of HMGB1 in Response to Proapoptotic Glioma Killing Strategies: Efficacy and Neurotoxicity
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Includes: Supplementary data