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Journal Articles

Vorinostat and Sorafenib Synergistically Kill Tumor Cells via FLIP Suppression and CD95 Activation

Guo Zhang, Margaret A. Park, Clint Mitchell, Hossein Hamed, Mohamed Rahmani, Aditi Pandya Martin, David T. Curiel, Adly Yacoub, Martin Graf, Ray Lee, John D. Roberts, Paul B. Fisher, Steven Grant, Paul Dent
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (17): 5385–5399.
https://doi.org/10.1158/1078-0432.CCR-08-0469
Published: 02 September 2008
View articletitled, Vorinostat and Sorafenib Synergistically Kill Tumor Cells via FLIP Suppression and CD95 Activation
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Includes: Supplementary data
Journal Articles

A Fiber-Modified Mesothelin Promoter–Based Conditionally Replicating Adenovirus for Treatment of Ovarian Cancer

Yuko Tsuruta, Larisa Pereboeva, Martina Breidenbach, Daniel T. Rein, Minghui Wang, Ronald D. Alvarez, Gene P. Siegal, Paul Dent, Paul B. Fisher, David T. Curiel
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (11): 3582–3588.
https://doi.org/10.1158/1078-0432.CCR-07-5053
Published: 02 June 2008
View articletitled, A Fiber-Modified Mesothelin Promoter–Based Conditionally Replicating Adenovirus for Treatment of Ovarian Cancer
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Journal Articles

Interactions between Bortezomib and Romidepsin and Belinostat in Chronic Lymphocytic Leukemia Cells

Yun Dai, Shuang Chen, Lora B. Kramer, Vanessa L. Funk, Paul Dent, Steven Grant
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (2): 549–558.
https://doi.org/10.1158/1078-0432.CCR-07-1934
Published: 25 January 2008
View articletitled, Interactions between Bortezomib and Romidepsin and Belinostat in Chronic Lymphocytic Leukemia Cells
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Includes: Supplementary data
Journal Articles

Synergistic Interactions between Vorinostat and Sorafenib in Chronic Myelogenous Leukemia Cells Involve Mcl-1 and p21CIP1 Down-Regulation

Girija Dasmahapatra, Nitin Yerram, Yun Dai, Paul Dent, Steven Grant
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (14): 4280–4290.
https://doi.org/10.1158/1078-0432.CCR-07-0835
Published: 18 July 2007
View articletitled, Synergistic Interactions between Vorinostat and Sorafenib in Chronic Myelogenous Leukemia Cells Involve Mcl-1 and p21CIP1 Down-Regulation
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Journal Articles

A Mosaic Fiber Adenovirus Serotype 5 Vector Containing Reovirus σ1 and Adenovirus Serotype 3 Knob Fibers Increases Transduction in an Ovarian Cancer Ex vivo System via a Coxsackie and Adenovirus Receptor–Independent Pathway

Yuko Tsuruta, Larisa Pereboeva, Joel N. Glasgow, Daniel T. Rein, Yosuke Kawakami, Ronald D. Alvarez, Rodney P. Rocconi, Gene P. Siegal, Paul Dent, Paul B. Fisher, David T. Curiel
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (9): 2777–2783.
https://doi.org/10.1158/1078-0432.CCR-06-2706
Published: 01 May 2007
View articletitled, A Mosaic Fiber Adenovirus Serotype 5 Vector Containing Reovirus σ1 and Adenovirus Serotype 3 Knob Fibers Increases Transduction in an Ovarian Cancer Ex vivo System via a Coxsackie and Adenovirus Receptor–Independent Pathway
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Journal Articles

Synergistic Interactions between DMAG and Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitors in Bcr/abl+ Leukemia Cells Sensitive and Resistant to Imatinib Mesylate

Tri K. Nguyen, Mohamed Rahmani, Ning Gao, Lora Kramer, Amie S. Corbin, Brian J. Druker, Paul Dent, Steven Grant
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (7): 2239–2247.
https://doi.org/10.1158/1078-0432.CCR-05-2282
Published: 11 April 2006
View articletitled, Synergistic Interactions between DMAG and Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitors in Bcr/abl+ Leukemia Cells Sensitive and Resistant to Imatinib Mesylate
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Journal Articles

The Farnesyltransferase Inhibitor L744832 Potentiates UCN-01–Induced Apoptosis in Human Multiple Myeloma Cells

Xin-Yan Pei, Yun Dai, Mohamed Rahmani, Weiqun Li, Paul Dent, Steven Grant
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (12): 4589–4600.
https://doi.org/10.1158/1078-0432.CCR-04-2346
Published: 15 June 2005
View articletitled, The Farnesyltransferase Inhibitor L744832 Potentiates UCN-01–Induced Apoptosis in Human Multiple Myeloma Cells
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Journal Articles

Ionizing Radiation Causes a Dose-Dependent Release of Transforming Growth Factor α In vitro from Irradiated Xenografts and during Palliative Treatment of Hormone-Refractory Prostate Carcinoma

Michael Hagan, Adly Yacoub, Paul Dent
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (17): 5724–5731.
https://doi.org/10.1158/1078-0432.CCR-04-0420
Published: 08 September 2004
View articletitled, Ionizing Radiation Causes a Dose-Dependent Release of Transforming Growth Factor α In vitro from Irradiated Xenografts and during Palliative Treatment of Hormone-Refractory Prostate Carcinoma
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Journal Articles

Kinase Inhibitors and Cytotoxic Drug Resistance

Steven Grant, Paul Dent
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (7): 2205–2207.
https://doi.org/10.1158/1078-0432.CCR-0001-4
Published: 08 April 2004
View articletitled, Kinase Inhibitors and Cytotoxic Drug Resistance
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Journal Articles

Melanoma Differentiation-associated 7 (Interleukin 24) Inhibits Growth and Enhances Radiosensitivity of Glioma Cells in Vitro and in Vivo

Adly Yacoub, Clint Mitchell, Andrea Lister, Irina V. Lebedeva, Devanand Sarkar, Zao-Zhong Su, Carter Sigmon, Robert McKinstry, Viswanathan Ramakrishnan, Liang Qiao, William C. Broaddus, Rahul V. Gopalkrishnan, Steven Grant, Paul B. Fisher, Paul Dent
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (9): 3272–3281.
Published: 05 September 2003
View articletitled, Melanoma Differentiation-associated 7 (Interleukin 24) Inhibits Growth and Enhances Radiosensitivity of Glioma Cells in Vitro and in Vivo
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Journal Articles

Flavopiridol Potentiates STI571-induced Mitochondrial Damage and Apoptosis in BCR-ABL-positive Human Leukemia Cells

Chunrong Yu, Geoffrey Krystal, Paul Dent, Steven Grant
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (9): 2976–2984.
Published: 01 September 2002
View articletitled, Flavopiridol Potentiates STI571-induced Mitochondrial Damage and Apoptosis in BCR-ABL-positive Human Leukemia Cells
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Journal Articles

Pharmacologic Interruption of the Mitogen-activated Extracellular-regulated Kinase/Mitogen-activated Protein Kinase Signal Transduction Pathway: Potential Role in PromotingCytotoxic Drug Action

Paul Dent, Steven Grant
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (4): 775–783.
Published: 01 April 2001
View articletitled, Pharmacologic Interruption of the Mitogen-activated Extracellular-regulated Kinase/Mitogen-activated Protein Kinase Signal Transduction Pathway: Potential Role in PromotingCytotoxic Drug Action
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Journal Articles

Radiosensitization of Malignant Glioma Cells through Overexpression of Dominant-Negative Epidermal Growth Factor Receptor

Guido Lammering, Kristoffer Valerie, Peck-Sun Lin, Ross B. Mikkelsen, Joseph N. Contessa, Jeffrey P. Feden, Julie Farnsworth, Paul Dent, Rupert K. Schmidt-Ullrich
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (3): 682–690.
Published: 01 March 2001
View articletitled, Radiosensitization of Malignant Glioma Cells through Overexpression of Dominant-Negative Epidermal Growth Factor Receptor
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Journal Articles

Interactions between 2-Fluoroadenine 9-β-d-Arabinofuranoside and the Kinase Inhibitor UCN-01 in Human Leukemia and Lymphoma Cells1

Sarah Harvey, Roy Decker, Yun Dai, Gregory Schaefer, Lin Tang, Lora Kramer, Paul Dent, Steven Grant
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (2): 320–330.
Published: 01 February 2001
View articletitled, Interactions between 2-Fluoroadenine 9-β-d-Arabinofuranoside and the Kinase Inhibitor UCN-01 in Human Leukemia and Lymphoma Cells1
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Journal Articles

The Inducible Expression of Dominant-Negative Epidermal Growth Factor Receptor-CD533 Results in Radiosensitization of Human Mammary Carcinoma Cells

Joseph N. Contessa, Dean B. Reardon, Daniel Todd, Paul Dent, Ross B. Mikkelsen, Kristoffer Valerie, Geoffrey D. Bowers, Rupert K. Schmidt-Ullrich
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (2): 405–411.
Published: 01 February 1999
View articletitled, The Inducible Expression of Dominant-Negative Epidermal Growth Factor Receptor-CD533 Results in Radiosensitization of Human Mammary Carcinoma Cells
Open the PDF for The Inducible Expression of Dominant-Negative Epidermal Growth Factor Receptor-CD533 Results in Radiosensitization of Human Mammary Carcinoma Cells in another window