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Journal Articles

Abstract 44: Monitoring of ctDNA burden from noncoding DNA

Guo Yu, Zhong Wee Poh, Guanhua Zhu, Iain Tan, Sarah Ng, Patrick Tan, Anders Skanderup
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (12_Supplement_1): 44.
https://doi.org/10.1158/1557-3265.ADVPRECMED20-44
Published: 15 June 2020
View article titled, Abstract 44: Monitoring of ctDNA burden from noncoding DNA
Journal Articles

Real-Time Tumor Gene Expression Profiling to Direct Gastric Cancer Chemotherapy: Proof-of-Concept “3G” Trial

Wei Peng Yong, Sun Young Rha, Iain Bee-Huat Tan, Su-Pin Choo, Nicholas L. Syn, Vivien Koh, Shi-Hui Tan, Bernadette Reyna Asuncion, Raghav Sundar, Jimmy Bok-Yan So, Asim Shabbir, Chee-Seng Tan, Hyo-Song Kim, Minkyu Jung, Hyun Cheol Chung, Matthew C.H. Ng, David Wai-Meng Tai, Ming-Hui Lee, Jeanie Wu, Khay Guan Yeoh, Patrick Tan
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (21): 5272–5281.
https://doi.org/10.1158/1078-0432.CCR-18-0193
Published: 01 November 2018
View article titled, Real-Time Tumor Gene Expression Profiling to Direct Gastric Cancer Chemotherapy: Proof-of-Concept “3G” Trial
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Includes: Supplementary data
Journal Articles

Clinical Utility of a STAT3-Regulated miRNA-200 Family Signature with Prognostic Potential in Early Gastric Cancer

Liang Yu, Di Wu, Hugh Gao, Jesse J. Balic, Anna Tsykin, Tae-Su Han, You Dong Liu, Catherine L. Kennedy, Ji Kun Li, Jie Qi Mao, Patrick Tan, Masanobu Oshima, Gregory J. Goodall, Brendan J. Jenkins
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (6): 1459–1472.
https://doi.org/10.1158/1078-0432.CCR-17-2485
Published: 14 March 2018
View article titled, Clinical Utility of a STAT3-Regulated miRNA-200 Family Signature with Prognostic Potential in Early Gastric Cancer
Open the PDF for Clinical Utility of a STAT3-Regulated miRNA-200 Family Signature with Prognostic Potential in Early Gastric Cancer in another window
Includes: Supplementary data
Journal Articles

Pharmacogenetic Analysis of the UK MRC (Medical Research Council) MAGIC Trial: Association of Polymorphisms with Toxicity and Survival in Patients Treated with Perioperative Epirubicin, Cisplatin, and 5-fluorouracil (ECF) Chemotherapy

Elizabeth Smyth, Shenli Zhang, David Cunningham, Andrew Wotherspoon, Richie Soong, Clare Peckitt, Nicola Valeri, Matteo Fassan, Massimo Rugge, Alicia Okines, William Allum, Sally Stenning, Matthew Nankivell, Ruth Langley, Patrick Tan
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (24): 7543–7549.
https://doi.org/10.1158/1078-0432.CCR-16-3142
Published: 14 December 2017
View article titled, Pharmacogenetic Analysis of the UK MRC (Medical Research Council) MAGIC Trial: Association of Polymorphisms with Toxicity and Survival in Patients Treated with Perioperative Epirubicin, Cisplatin, and 5-fluorouracil (ECF) Chemotherapy
Open the PDF for Pharmacogenetic Analysis of the UK MRC (Medical Research Council) MAGIC Trial: Association of Polymorphisms with Toxicity and Survival in Patients Treated with Perioperative Epirubicin, Cisplatin, and 5-fluorouracil (ECF) Chemotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract PR1: Genomic discovery of CD44-SLC1A2 gene fusions in gastric cancer

Jiong Tao, Kalpana Ramnarayanan, Baohua Huang, Iain Beehuat Tan, Chia Huey Ooi, Minghui Lee, Shenli Zhang, Siew Hong Leong, Tatiana Ivanova, Kumaresan Ganesan, Veena Gopalakrishnan, Sun Young Rha, Hyun Cheol Chung, Celestial Yap, Nallasivam Palanisamy, Patrick Tan
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (14_Supplement): PR1.
https://doi.org/10.1158/1078-0432.TCMUSA10-PR1
Published: 02 February 2016
View article titled, Abstract PR1: Genomic discovery of <em>CD44-SLC1A2</em> gene fusions in gastric cancer
Journal Articles

Integrative Analysis of Head and Neck Cancer Identifies Two Biologically Distinct HPV and Three Non-HPV Subtypes

Michaela K. Keck, Zhixiang Zuo, Arun Khattri, Thomas P. Stricker, Christopher D. Brown, Matin Imanguli, Damian Rieke, Katharina Endhardt, Petra Fang, Johannes Brägelmann, Rebecca DeBoer, Mohamed El-Dinali, Serdal Aktolga, Zhengdeng Lei, Patrick Tan, Steve G. Rozen, Ravi Salgia, Ralph R. Weichselbaum, Mark W. Lingen, Michael D. Story, K. Kian Ang, Ezra E.W. Cohen, Kevin P. White, Everett E. Vokes, Tanguy Y. Seiwert
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (4): 870–881.
https://doi.org/10.1158/1078-0432.CCR-14-2481
Published: 16 February 2015
View article titled, Integrative Analysis of Head and Neck Cancer Identifies Two Biologically Distinct HPV and Three Non-HPV Subtypes
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Includes: Supplementary data
Journal Articles

Functional and Prognostic Insights into the Altered Cancer Genome

Jinqiu Zhang, Xuejing Liu, Arpita Datta, Bing Lim, Krishna Karuturi, Patrick Tan, Philippe Broet, Sophie Broet, Lance Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (22_Supplement): PL07-04.
Published: 15 August 2014
View article titled, Functional and Prognostic Insights into the Altered Cancer Genome
Journal Articles

The role of BLIMP1 in lymphomagenesis

Junli Yan, Jianming Jiang, Cheng Aeng Lim, Qiang Wu, Patrick Tan, Keh Chuang Chin, Huck Hui Ng
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (22_Supplement): C75.
Published: 15 August 2014
View article titled, The role of BLIMP1 in lymphomagenesis
Journal Articles

PLA2G2A, a novel β-catenin/TCF target gene, inhibits gastric cancer invasion and metastasis

Kumaresan Ganesan, Tatiana Ivanova, Yongui Wu, Jeanie Wu, Yu Kun, Ming Hui, Vikneswari Rajasegaran, Heike Grabsch, Gerrit Meijer, Suet Leung, Oi Kon, Patrick Tan
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (22_Supplement): B62.
Published: 15 August 2014
View article titled, <em>PLA2G2A</em>, a novel β-catenin/TCF target gene, inhibits gastric cancer invasion and metastasis
Journal Articles

Fine-scale variation in a cancer-specific signature of stably-expressed genes correlates with metastatic capacity and clinical outcome

Kun Yu, Jeanie Wu, Patrick Tan
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (22_Supplement): B53.
Published: 15 August 2014
View article titled, Fine-scale variation in a cancer-specific signature of stably-expressed genes correlates with metastatic capacity and clinical outcome
Journal Articles

A Signature Predicting Poor Prognosis in Gastric and Ovarian Cancer Represents a Coordinated Macrophage and Stromal Response

Rita A. Busuttil, Joshy George, Richard W. Tothill, Kylie Ioculano, Adam Kowalczyk, Catherine Mitchell, Stephen Lade, Patrick Tan, Izhak Haviv, Alex Boussioutas
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (10): 2761–2772.
https://doi.org/10.1158/1078-0432.CCR-13-3049
Published: 14 May 2014
View article titled, A Signature Predicting Poor Prognosis in Gastric and Ovarian Cancer Represents a Coordinated Macrophage and Stromal Response
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Includes: Supplementary data
Journal Articles

TP53 Genomic Status Regulates Sensitivity of Gastric Cancer Cells to the Histone Methylation Inhibitor 3-Deazaneplanocin A (DZNep)

Lai Ling Cheng, Yoko Itahana, Zheng Deng Lei, Na-Yu Chia, Yonghui Wu, Yingnan Yu, Shen Li Zhang, Aye Aye Thike, Anuradha Pandey, Steve Rozen, Pieter Mathijs Voorhoeve, Qiang Yu, Puay Hoon Tan, Boon Huat Bay, Koji Itahana, Patrick Tan
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (15): 4201–4212.
https://doi.org/10.1158/1078-0432.CCR-12-0036
Published: 30 July 2012
View article titled, <em>TP53</em> Genomic Status Regulates Sensitivity of Gastric Cancer Cells to the Histone Methylation Inhibitor 3-Deazaneplanocin A (DZNep)
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Includes: Supplementary data
Journal Articles

First Evidence That γ-Tocotrienol Inhibits the Growth of Human Gastric Cancer and Chemosensitizes It to Capecitabine in a Xenograft Mouse Model through the Modulation of NF-κB Pathway

Kanjoormana A. Manu, Muthu K. Shanmugam, Lalitha Ramachandran, Feng Li, Chee Wai Fong, Alan Prem Kumar, Patrick Tan, Gautam Sethi
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (8): 2220–2229.
https://doi.org/10.1158/1078-0432.CCR-11-2470
Published: 16 April 2012
View article titled, First Evidence That γ-Tocotrienol Inhibits the Growth of Human Gastric Cancer and Chemosensitizes It to Capecitabine in a Xenograft Mouse Model through the Modulation of NF-κB Pathway
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Journal Articles

Genomic Profiles Specific to Patient Ethnicity in Lung Adenocarcinoma

Philippe Broët, Cyril Dalmasso, Eng Huat Tan, Marco Alifano, Shenli Zhang, Jeanie Wu, Ming Hui Lee, Jean-François Régnard, Darren Lim, Heng Nung Koong, Thirugnanam Agasthian, Lance D. Miller, Elaine Lim, Sophie Camilleri-Broët, Patrick Tan
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (11): 3542–3550.
https://doi.org/10.1158/1078-0432.CCR-10-2185
Published: 01 June 2011
View article titled, Genomic Profiles Specific to Patient Ethnicity in Lung Adenocarcinoma
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Journal Articles

Genomic Loss of miR-486 Regulates Tumor Progression and the OLFM4 Antiapoptotic Factor in Gastric Cancer

Hue-Kian Oh, Angie Lay-Keng Tan, Kakoli Das, Chia-Huey Ooi, Nian-Tao Deng, Iain BeeHuat Tan, Emmanuel Beillard, Julian Lee, Kalpana Ramnarayanan, Sun-Young Rha, Nallasivam Palanisamy, P. Mathijs Voorhoeve, Patrick Tan
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (9): 2657–2667.
https://doi.org/10.1158/1078-0432.CCR-10-3152
Published: 01 May 2011
View article titled, Genomic Loss of <em>miR-486</em> Regulates Tumor Progression and the <em>OLFM4</em> Antiapoptotic Factor in Gastric Cancer
Open the PDF for Genomic Loss of <em>miR-486</em> Regulates Tumor Progression and the <em>OLFM4</em> Antiapoptotic Factor in Gastric Cancer in another window
Includes: Supplementary data
Journal Articles

Clinical Validation of a Customized Multiple Signature Microarray for Breast Cancer

Benita K.T. Tan, Lay Keng Tan, Kun Yu, Puay Hoon Tan, Ming Lee, Lang Hiong Sii, Chow Yin Wong, Gay Hui Ho, Allen W.Y. Yeo, Pierce K.H. Chow, Heng Nung Koong, Wei Sean Yong, Dennis T.H. Lim, London L.P.J. Ooi, Khee Chee Soo, Patrick Tan
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (2): 461–469.
https://doi.org/10.1158/1078-0432.CCR-07-0999
Published: 25 January 2008
View article titled, Clinical Validation of a Customized Multiple Signature Microarray for Breast Cancer
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Includes: Supplementary data
Journal Articles

A Modular Analysis of Breast Cancer Reveals a Novel Low-Grade Molecular Signature in Estrogen Receptor–Positive Tumors

Kun Yu, Kumaresan Ganesan, Lance D. Miller, Patrick Tan
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (11): 3288–3296.
https://doi.org/10.1158/1078-0432.CCR-05-1530
Published: 01 June 2006
View article titled, A Modular Analysis of Breast Cancer Reveals a Novel Low-Grade Molecular Signature in Estrogen Receptor–Positive Tumors
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Includes: Supplementary data
Journal Articles

Conservation of Breast Cancer Molecular Subtypes and Transcriptional Patterns of Tumor Progression Across Distinct Ethnic Populations

Kun Yu, Chee How Lee, Puay Hoon Tan, Patrick Tan
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (16): 5508–5517.
https://doi.org/10.1158/1078-0432.CCR-04-0085
Published: 24 August 2004
View article titled, Conservation of Breast Cancer Molecular Subtypes and Transcriptional Patterns of Tumor Progression Across Distinct Ethnic Populations
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Includes: Supplementary data
Journal Articles

Feasibility of Using Low-Volume Tissue Samples for Gene Expression Profiling of Advanced Non-Small Cell Lung Cancers

Elaine H. Lim, Amit Aggarwal, Thirugananam Agasthian, Poo-Sing Wong, Christie Tan, Eugene Sim, Lenny Tan, Poh-Sun Goh, Shih-Chang Wang, Kay-Leong Khoo, Amartya Mukherjee, See-Meng Khoo, Gerald Chua, Barbro Nilsson, Kang-Hoe Lee, Patrick Tan
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (16): 5980–5987.
Published: 15 December 2003
View article titled, Feasibility of Using Low-Volume Tissue Samples for Gene Expression Profiling of Advanced Non-Small Cell Lung Cancers
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