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Olaf Witt
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Journal Articles

The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

Juliane L. Buhl, Florian Selt, Thomas Hielscher, Romain Guiho, Jonas Ecker, Felix Sahm, Johannes Ridinger, Dennis Riehl, Diren Usta, Britta Ismer, Alexander C. Sommerkamp, J.P. Martinez-Barbera, Annika K. Wefers, Marc Remke, Daniel Picard, Stefan Pusch, Jan Gronych, Ina Oehme, Cornelis M. van Tilburg, Marcel Kool, Daniela Kuhn, David Capper, Andreas von Deimling, Martin U. Schuhmann, Christel Herold-Mende, Andrey Korshunov, Tilman Brummer, Stefan M. Pfister, David T.W. Jones, Olaf Witt, Till Milde
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1851–1866.
https://doi.org/10.1158/1078-0432.CCR-18-1965
Published: 15 March 2019
View article titled, The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma
Open the PDF for The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma in another window
Includes: Supplementary data
Journal Articles

Abstract A25: Establishment of orthotopic patient-derived xenograft models of pediatric brain tumors – the Heidelberg experience

Norman L. Mack, Sebastian Brabetz, Florian Selt, Xanthopolous Christina, David Sumerauer, Heidi Bächli, Arnulf Pekrun, Martin U. Schuhmann, Stefan M. Pfister, Olaf Witt, Till Milde, Marcel Kool
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): A25.
https://doi.org/10.1158/1557-3265.PDX16-A25
Published: 15 August 2016
View article titled, Abstract A25: Establishment of orthotopic patient-derived xenograft models of pediatric brain tumors – the Heidelberg experience
Journal Articles

Genetic Aberrations Leading to MAPK Pathway Activation Mediate Oncogene-Induced Senescence in Sporadic Pilocytic Astrocytomas

Karine Jacob, Dongh-Anh Quang-Khuong, David T.W. Jones, Hendrik Witt, Sally Lambert, Steffen Albrecht, Olaf Witt, Catherine Vezina, Margret Shirinian, Damien Faury, Miklos Garami, Peter Hauser, Almos Klekner, Laszlo Bognar, Jean-Pierre Farmer, Jose-Luis Montes, Jeffrey Atkinson, Cynthia Hawkins, Andrey Korshunov, V. Peter Collins, Stefan M. Pfister, Uri Tabori, Nada Jabado
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (14): 4650–4660.
https://doi.org/10.1158/1078-0432.CCR-11-0127
Published: 17 July 2011
View article titled, Genetic Aberrations Leading to MAPK Pathway Activation Mediate Oncogene-Induced Senescence in Sporadic Pilocytic Astrocytomas
Open the PDF for Genetic Aberrations Leading to MAPK Pathway Activation Mediate Oncogene-Induced Senescence in Sporadic Pilocytic Astrocytomas in another window
Includes: Supplementary data
Journal Articles

HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth

Till Milde, Ina Oehme, Andrey Korshunov, Annette Kopp-Schneider, Marc Remke, Paul Northcott, Hedwig E. Deubzer, Marco Lodrini, Michael D. Taylor, Andreas von Deimling, Stefan Pfister, Olaf Witt
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (12): 3240–3252.
https://doi.org/10.1158/1078-0432.CCR-10-0395
Published: 14 June 2010
View article titled, HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth
Open the PDF for HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth in another window
Includes: Supplementary data
Journal Articles

Histone Deacetylase 8 in Neuroblastoma Tumorigenesis

Ina Oehme, Hedwig E. Deubzer, Dennis Wegener, Diana Pickert, Jan-Peter Linke, Barbara Hero, Annette Kopp-Schneider, Frank Westermann, Scott M. Ulrich, Andreas von Deimling, Matthias Fischer, Olaf Witt
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (1): 91–99.
https://doi.org/10.1158/1078-0432.CCR-08-0684
Published: 31 December 2008
View article titled, Histone Deacetylase 8 in Neuroblastoma Tumorigenesis
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Includes: Supplementary data
Journal Articles

Cisplatin-Resistant Neuroblastoma Cells Express Enhanced Levels of Epidermal Growth Factor Receptor (EGFR) and Are Sensitive to Treatment with EGFR-Specific Toxins

Martin Michaelis, Jennifer Bliss, Sonja C. Arnold, Nora Hinsch, Florian Rothweiler, Hedwig E. Deubzer, Olaf Witt, Klaus Langer, Hans W. Doerr, Winfried S. Wels, Jindrich Cinatl, Jr.
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (20): 6531–6537.
https://doi.org/10.1158/1078-0432.CCR-08-0821
Published: 16 October 2008
View article titled, Cisplatin-Resistant Neuroblastoma Cells Express Enhanced Levels of Epidermal Growth Factor Receptor (EGFR) and Are Sensitive to Treatment with EGFR-Specific Toxins
Open the PDF for Cisplatin-Resistant Neuroblastoma Cells Express Enhanced Levels of Epidermal Growth Factor Receptor (EGFR) and Are Sensitive to Treatment with EGFR-Specific Toxins in another window