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Ola Landgren
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Journal Articles

Genomic Profiling to Contextualize the Results of Intervention for Smoldering Multiple Myeloma

Dickran Kazandjian, Benjamin Diamond, Marios Papadimitriou, Elizabeth Hill, Romanos Sklavenitis-Pistofidis, Bachisio Ziccheddu, Patrick Blaney, Monika Chojnacka, Michael Durante, Kylee Maclachlan, Ryan Young, Saad Usmani, Faith Davies, Gad Getz, Irene Ghobrial, Neha Korde, Gareth Morgan, Francesco Maura, Ola Landgren
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (19): 4482–4490.
https://doi.org/10.1158/1078-0432.CCR-24-0210
Published: 01 October 2024
View article titled, Genomic Profiling to Contextualize the Results of Intervention for Smoldering Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Impact of Rare Structural Variant Events in Newly Diagnosed Multiple Myeloma

Monika Chojnacka, Benjamin Diamond, Bachisio Ziccheddu, Even Rustad, Kylee Maclachlan, Marios Papadimitriou, Eileen M. Boyle, Patrick Blaney, Saad Usmani, Gareth Morgan, Ola Landgren, Francesco Maura
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (3): 575–585.
https://doi.org/10.1158/1078-0432.CCR-23-1045
Published: 01 February 2024
View article titled, Impact of Rare Structural Variant Events in Newly Diagnosed Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Multiomic Mapping of Acquired Chromosome 1 Copy-Number and Structural Variants to Identify Therapeutic Vulnerabilities in Multiple Myeloma

Eileen M. Boyle, Patrick Blaney, James H. Stoeckle, Yubao Wang, Hussein Ghamlouch, Dylan Gagler, Marc Braunstein, Louis Williams, Avital Tenenbaum, Ariel Siegel, Xiaoyi Chen, Gaurav Varma, Jason Avigan, Alexander Li, Monica Jinsi, David Kaminetzsky, Arnaldo Arbini, Lydia Montes, Jill Corre, Even H. Rustad, Ola Landgren, Francesco Maura, Brian A. Walker, Michael Bauer, Benedetto Bruno, Aristotelis Tsirigos, Faith E. Davies, Gareth J. Morgan
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (19): 3901–3913.
https://doi.org/10.1158/1078-0432.CCR-22-3209
Published: 02 October 2023
View article titled, Multiomic Mapping of Acquired Chromosome 1 Copy-Number and Structural Variants to Identify Therapeutic Vulnerabilities in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Sustained Minimal Residual Disease Negativity in Multiple Myeloma is Associated with Stool Butyrate and Healthier Plant-Based Diets

Urvi A. Shah, Kylee H. Maclachlan, Andriy Derkach, Meghan Salcedo, Kelly Barnett, Julia Caple, Jenna Blaslov, Linh Tran, Amanda Ciardiello, Miranda Burge, Tala Shekarkhand, Peter Adintori, Justin Cross, Matthew J. Pianko, Kinga Hosszu, Devin McAvoy, Sham Mailankody, Neha Korde, Malin Hultcrantz, Hani Hassoun, Carlyn R. Tan, Sydney X. Lu, Dhwani Patel, Benjamin Diamond, Gunjan Shah, Michael Scordo, Oscar Lahoud, David J. Chung, Heather Landau, Saad Z. Usmani, Sergio Giralt, Ying Taur, C. Ola Landgren, Gladys Block, Torin Block, Jonathan U. Peled, Marcel R.M. van den Brink, Alexander M. Lesokhin
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (23): 5149–5155.
https://doi.org/10.1158/1078-0432.CCR-22-0723
Published: 01 December 2022
View article titled, Sustained Minimal Residual Disease Negativity in Multiple Myeloma is Associated with Stool Butyrate and Healthier Plant-Based Diets
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Includes: Supplementary data
Journal Articles

Capture Rate of V(D)J Sequencing for Minimal Residual Disease Detection in Multiple Myeloma

Malin Hultcrantz, Even H. Rustad, Venkata Yellapantula, Allison Jacob, Theresia Akhlaghi, Neha Korde, Sham Mailankody, Alexander M. Lesokhin, Hani Hassoun, Eric L. Smith, Oscar B. Lahoud, Heather J. Landau, Gunjan L. Shah, Michael Scordo, David J. Chung, Sergio Giralt, Elli Papaemmanuil, Ola Landgren
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (10): 2160–2166.
https://doi.org/10.1158/1078-0432.CCR-20-2995
Published: 13 May 2022
View article titled, Capture Rate of V(D)J Sequencing for Minimal Residual Disease Detection in Multiple Myeloma
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Journal Articles

Functional Impact of Genomic Complexity on the Transcriptome of Multiple Myeloma

Bachisio Ziccheddu, Matteo C. Da Vià, Marta Lionetti, Akihiro Maeda, Silvia Morlupi, Matteo Dugo, Katia Todoerti, Stefania Oliva, Mattia D'Agostino, Paolo Corradini, Ola Landgren, Francesco Iorio, Loredana Pettine, Alessandra Pompa, Martina Manzoni, Luca Baldini, Antonino Neri, Francesco Maura, Niccolò Bolli
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (23): 6479–6490.
https://doi.org/10.1158/1078-0432.CCR-20-4366
Published: 01 December 2021
View article titled, Functional Impact of Genomic Complexity on the Transcriptome of Multiple Myeloma
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Journal Articles

Minimal Residual Disease in Myeloma: Application for Clinical Care and New Drug Registration

Kenneth C. Anderson, Daniel Auclair, Stacey J. Adam, Amit Agarwal, Melissa Anderson, Hervé Avet-Loiseau, Mark Bustoros, Jessica Chapman, Dana E. Connors, Ajeeta Dash, Alessandra Di Bacco, Ling Du, Thierry Facon, Juan Flores-Montero, Francesca Gay, Irene M. Ghobrial, Nicole J. Gormley, Ira Gupta, Howard Higley, Jens Hillengass, Bindu Kanapuru, Dickran Kazandjian, Gary J. Kelloff, Ilan R. Kirsch, Brandon Kremer, Ola Landgren, Elizabeth Lightbody, Oliver C. Lomas, Sagar Lonial, María-Victoria Mateos, Rocio Montes de Oca, Lata Mukundan, Nikhil C. Munshi, Elizabeth K. O'Donnell, Alberto Orfao, Bruno Paiva, Reshma Patel, Trevor J. Pugh, Karthik Ramasamy, Jill Ray, Mikhail Roshal, Jeremy A. Ross, Caroline C. Sigman, Katie L. Thoren, Suzanne Trudel, Gary Ulaner, Nancy Valente, Brendan M. Weiss, Elena Zamagni, Shaji K. Kumar
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (19): 5195–5212.
https://doi.org/10.1158/1078-0432.CCR-21-1059
Published: 01 October 2021
View article titled, Minimal Residual Disease in Myeloma: Application for Clinical Care and New Drug Registration
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Journal Articles

Initial Whole-Genome Sequencing of Plasma Cell Neoplasms in First Responders and Recovery Workers Exposed to the World Trade Center Attack of September 11, 2001

Francesco Maura, Benjamin Diamond, Kylee H. Maclachlan, Andriy Derkach, Venkata D. Yellapantula, Even H. Rustad, Malin Hultcrantz, Urvi A. Shah, Jessica Hong, Heather J. Landau, Christine A. Iacobuzio-Donahue, Elli Papaemmanuil, Shani Irby, Laura Crowley, Michael Crane, Mayris P. Webber, David G. Goldfarb, Rachel Zeig-Owens, Orsi Giricz, Amit Verma, David J. Prezant, Ahmet Dogan, Sohrab P. Shah, Yanming Zhang, Ola Landgren
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (7): 2111–2118.
https://doi.org/10.1158/1078-0432.CCR-20-2245
Published: 01 April 2021
View article titled, Initial Whole-Genome Sequencing of Plasma Cell Neoplasms in First Responders and Recovery Workers Exposed to the World Trade Center Attack of September 11, 2001
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Includes: Supplementary data
Journal Articles

Designing Evolutionary-based Interception Strategies to Block the Transition from Precursor Phases to Multiple Myeloma

Francesco Maura, Ola Landgren, Gareth J. Morgan
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (1): 15–23.
https://doi.org/10.1158/1078-0432.CCR-20-1395
Published: 04 January 2021
View article titled, Designing Evolutionary-based Interception Strategies to Block the Transition from Precursor Phases to Multiple Myeloma
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Includes: Supplementary data
Journal Articles

The Role of Minimal Residual Disease Testing in Myeloma Treatment Selection and Drug Development: Current Value and Future Applications

Kenneth C. Anderson, Daniel Auclair, Gary J. Kelloff, Caroline C. Sigman, Hervé Avet-Loiseau, Ann T. Farrell, Nicole J. Gormley, Shaji K. Kumar, Ola Landgren, Nikhil C. Munshi, Michele Cavo, Faith E. Davies, Alessandra Di Bacco, Jennifer S. Dickey, Steven I. Gutman, Howard R. Higley, Mohamad A. Hussein, J. Milburn Jessup, Ilan R. Kirsch, Richard F. Little, Robert D. Loberg, Jens G. Lohr, Lata Mukundan, James L. Omel, Trevor J. Pugh, Gregory H. Reaman, Michael D. Robbins, A. Kate Sasser, Nancy Valente, Elena Zamagni
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (15): 3980–3993.
https://doi.org/10.1158/1078-0432.CCR-16-2895
Published: 01 August 2017
View article titled, The Role of Minimal Residual Disease Testing in Myeloma Treatment Selection and Drug Development: Current Value and Future Applications
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Includes: Supplementary data
Journal Articles

New Developments in Diagnosis, Prognosis, and Assessment of Response in Multiple Myeloma

Ola Landgren, S. Vincent Rajkumar
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (22): 5428–5433.
https://doi.org/10.1158/1078-0432.CCR-16-0866
Published: 14 November 2016
View article titled, New Developments in Diagnosis, Prognosis, and Assessment of Response in Multiple Myeloma
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Journal Articles

Checkpoint Inhibition of KIR2D with the Monoclonal Antibody IPH2101 Induces Contraction and Hyporesponsiveness of NK Cells in Patients with Myeloma

Mattias Carlsten, Neha Korde, Ritesh Kotecha, Robert Reger, Simona Bor, Dickran Kazandjian, Ola Landgren, Richard W. Childs
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (21): 5211–5222.
https://doi.org/10.1158/1078-0432.CCR-16-1108
Published: 31 October 2016
View article titled, Checkpoint Inhibition of KIR2D with the Monoclonal Antibody IPH2101 Induces Contraction and Hyporesponsiveness of NK Cells in Patients with Myeloma
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Includes: Supplementary data
Journal Articles

Impact of Genes Highly Correlated with MMSET Myeloma on the Survival of Non-MMSET Myeloma Patients

S. Peter Wu, Ruth M. Pfeiffer, Inhye E. Ahn, Sham Mailankody, Pieter Sonneveld, Mark van Duin, Nikhil C. Munshi, Brian A. Walker, Gareth Morgan, Ola Landgren
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16): 4039–4044.
https://doi.org/10.1158/1078-0432.CCR-15-2366
Published: 14 August 2016
View article titled, Impact of Genes Highly Correlated with <em>MMSET</em> Myeloma on the Survival of Non-<em>MMSET</em> Myeloma Patients
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Includes: Supplementary data
Journal Articles

A Phase II Trial of AZD6244 (Selumetinib, ARRY-142886), an Oral MEK1/2 Inhibitor, in Relapsed/Refractory Multiple Myeloma

Beata Holkova, Adriana Zingone, Maciej Kmieciak, Prithviraj Bose, Ashraf Z. Badros, Peter M. Voorhees, Rachid Baz, Neha Korde, Hui-Yi Lin, Jin-Qiu Chen, Michelle Herrmann, Liqiang Xi, Mark Raffeld, Xiuhua Zhao, Wen Wan, Mary Beth Tombes, Ellen Shrader, Caryn Weir-Wiggins, Heidi Sankala, Kevin T. Hogan, Austin Doyle, Christina M. Annunziata, Martha Wellons, John D. Roberts, Daniel Sullivan, Ola Landgren, Steven Grant
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (5): 1067–1075.
https://doi.org/10.1158/1078-0432.CCR-15-1076
Published: 29 February 2016
View article titled, A Phase II Trial of AZD6244 (Selumetinib, ARRY-142886), an Oral MEK1/2 Inhibitor, in Relapsed/Refractory Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Biologic Frontiers in Multiple Myeloma: From Biomarker Identification to Clinical Practice

Ola Landgren, Gareth J. Morgan
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (4): 804–813.
https://doi.org/10.1158/1078-0432.CCR-13-2159
Published: 16 February 2014
View article titled, Biologic Frontiers in Multiple Myeloma: From Biomarker Identification to Clinical Practice
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Journal Articles

From Myeloma Precursor Disease to Multiple Myeloma: New Diagnostic Concepts and Opportunities for Early Intervention

Ola Landgren, Robert A. Kyle, S. Vincent Rajkumar
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (6): 1243–1252.
https://doi.org/10.1158/1078-0432.CCR-10-1822
Published: 15 March 2011
View article titled, From Myeloma Precursor Disease to Multiple Myeloma: New Diagnostic Concepts and Opportunities for Early Intervention
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