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Journal Articles

How to Train Your T Cells: Overcoming Immune Dysfunction in Multiple Myeloma

Adam D. Cohen, Noopur Raje, Jessica A. Fowler, Khalid Mezzi, Emma C. Scott, Madhav V. Dhodapkar
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (7): 1541–1554.
https://doi.org/10.1158/1078-0432.CCR-19-2111
Published: 01 April 2020
View article titled, How to Train Your T Cells: Overcoming Immune Dysfunction in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

A Phase Ib/II Study of Oprozomib in Patients with Advanced Multiple Myeloma and Waldenström Macroglobulinemia

Irene M. Ghobrial, Ravi Vij, David Siegel, Ashraf Badros, Jonathan Kaufman, Noopur Raje, Andrzej Jakubowiak, Michael R. Savona, Mihaela Obreja, Jesus G. Berdeja
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (16): 4907–4916.
https://doi.org/10.1158/1078-0432.CCR-18-3728
Published: 15 August 2019
View article titled, A Phase Ib/II Study of Oprozomib in Patients with Advanced Multiple Myeloma and Waldenström Macroglobulinemia
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Includes: Supplementary data
Journal Articles

Ricolinostat, the First Selective Histone Deacetylase 6 Inhibitor, in Combination with Bortezomib and Dexamethasone for Relapsed or Refractory Multiple Myeloma

Dan T. Vogl, Noopur Raje, Sundar Jagannath, Paul Richardson, Parameswaran Hari, Robert Orlowski, Jeffrey G. Supko, David Tamang, Min Yang, Simon S. Jones, Catherine Wheeler, Robert J. Markelewicz, Sagar Lonial
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (13): 3307–3315.
https://doi.org/10.1158/1078-0432.CCR-16-2526
Published: 02 July 2017
View article titled, Ricolinostat, the First Selective Histone Deacetylase 6 Inhibitor, in Combination with Bortezomib and Dexamethasone for Relapsed or Refractory Multiple Myeloma
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Journal Articles

Bone Marker–Directed Dosing of Zoledronic Acid for the Prevention of Skeletal Complications in Patients with Multiple Myeloma: Results of the Z-MARK Study

Noopur Raje, Robert Vescio, Charles W. Montgomery, Ashraf Badros, Nikhil Munshi, Richard Orlowski, Joseph T. Hadala, Ghulam Warsi, Eliza Argonza-Aviles, Solveig G. Ericson, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (6): 1378–1384.
https://doi.org/10.1158/1078-0432.CCR-15-1864
Published: 14 March 2016
View article titled, Bone Marker–Directed Dosing of Zoledronic Acid for the Prevention of Skeletal Complications in Patients with Multiple Myeloma: Results of the Z-MARK Study
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Journal Articles

Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma

Güllü Görgün, Mehmet K. Samur, Kristen B. Cowens, Steven Paula, Giada Bianchi, Julie E. Anderson, Randie E. White, Ahaana Singh, Hiroto Ohguchi, Rikio Suzuki, Shohei Kikuchi, Takeshi Harada, Teru Hideshima, Yu-Tzu Tai, Jacob P. Laubach, Noopur Raje, Florence Magrangeas, Stephane Minvielle, Herve Avet-Loiseau, Nikhil C. Munshi, David M. Dorfman, Paul G. Richardson, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (20): 4607–4618.
https://doi.org/10.1158/1078-0432.CCR-15-0200
Published: 14 October 2015
View article titled, Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Preclinical Activity of the Oral Proteasome Inhibitor MLN9708 in Myeloma Bone Disease

Antonio Garcia-Gomez, Dalia Quwaider, Miriam Canavese, Enrique M. Ocio, Ze Tian, Juan F. Blanco, Allison J. Berger, Carlos Ortiz-de-Solorzano, Teresa Hernández-Iglesias, Anton C.M. Martens, Richard W.J. Groen, Joaquín Mateo-Urdiales, Susana Fraile, Miguel Galarraga, Dharminder Chauhan, Jesús F. San Miguel, Noopur Raje, Mercedes Garayoa
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (6): 1542–1554.
https://doi.org/10.1158/1078-0432.CCR-13-1657
Published: 13 March 2014
View article titled, Preclinical Activity of the Oral Proteasome Inhibitor MLN9708 in Myeloma Bone Disease
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Journal Articles

Vaccination with Dendritic Cell/Tumor Fusions following Autologous Stem Cell Transplant Induces Immunologic and Clinical Responses in Multiple Myeloma Patients

Jacalyn Rosenblatt, Irit Avivi, Baldev Vasir, Lynne Uhl, Nikhil C. Munshi, Tami Katz, Bimalangshu R. Dey, Poorvi Somaiya, Heidi Mills, Federico Campigotto, Edie Weller, Robin Joyce, James D. Levine, Dimitrios Tzachanis, Paul Richardson, Jacob Laubach, Noopur Raje, Vassiliki Boussiotis, Yan Emily Yuan, Lina Bisharat, Viki Held, Jacob Rowe, Kenneth Anderson, Donald Kufe, David Avigan
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (13): 3640–3648.
https://doi.org/10.1158/1078-0432.CCR-13-0282
Published: 30 June 2013
View article titled, Vaccination with Dendritic Cell/Tumor Fusions following Autologous Stem Cell Transplant Induces Immunologic and Clinical Responses in Multiple Myeloma Patients
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Includes: Supplementary data
Journal Articles

In Vitro and In Vivo Selective Antitumor Activity of a Novel Orally Bioavailable Proteasome Inhibitor MLN9708 against Multiple Myeloma Cells

Dharminder Chauhan, Ze Tian, Bin Zhou, Deborah Kuhn, Robert Orlowski, Noopur Raje, Paul Richardson, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (16): 5311–5321.
https://doi.org/10.1158/1078-0432.CCR-11-0476
Published: 14 August 2011
View article titled, <em>In Vitro</em> and <em>In Vivo</em> Selective Antitumor Activity of a Novel Orally Bioavailable Proteasome Inhibitor MLN9708 against Multiple Myeloma Cells
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Journal Articles

Antimyeloma Activity of a Multitargeted Kinase Inhibitor, AT9283, via Potent Aurora Kinase and STAT3 Inhibition Either Alone or in Combination with Lenalidomide

Loredana Santo, Teru Hideshima, Diana Cirstea, Madhavi Bandi, Erik A. Nelson, Gullu Gorgun, Scott Rodig, Sonia Vallet, Samantha Pozzi, Kishan Patel, Christine Unitt, Matt Squires, Yiguo Hu, Dharminder Chauhan, Anuj Mahindra, Nikhil C. Munshi, Kenneth C. Anderson, Noopur Raje
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (10): 3259–3271.
https://doi.org/10.1158/1078-0432.CCR-10-3012
Published: 15 May 2011
View article titled, Antimyeloma Activity of a Multitargeted Kinase Inhibitor, AT9283, via Potent Aurora Kinase and STAT3 Inhibition Either Alone or in Combination with Lenalidomide
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Journal Articles

Advances in the Biology and Treatment of Bone Disease in Multiple Myeloma

Noopur Raje, G. David Roodman
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (6): 1278–1286.
https://doi.org/10.1158/1078-0432.CCR-10-1804
Published: 15 March 2011
View article titled, Advances in the Biology and Treatment of Bone Disease in Multiple Myeloma
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Journal Articles

Novel Bone-Targeted Strategies in Oncology

Sonia Vallet, Matthew R. Smith, Noopur Raje
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (16): 4084–4093.
https://doi.org/10.1158/1078-0432.CCR-10-0600
Published: 11 August 2010
View article titled, Novel Bone-Targeted Strategies in Oncology
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Journal Articles

High-Dose Zoledronic Acid Impacts Bone Remodeling with Effects on Osteoblastic Lineage and Bone Mechanical Properties

Samantha Pozzi, Sonia Vallet, Siddhartha Mukherjee, Diana Cirstea, Nileshwari Vaghela, Loredana Santo, Eyal Rosen, Hiroshi Ikeda, Yutaka Okawa, Tanyel Kiziltepe, Jesse Schoonmaker, Wanling Xie, Teru Hideshima, Edie Weller, Mary L. Bouxsein, Nikhil C. Munshi, Kenneth C. Anderson, Noopur Raje
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (18): 5829–5839.
https://doi.org/10.1158/1078-0432.CCR-09-0426
Published: 14 September 2009
View article titled, High-Dose Zoledronic Acid Impacts Bone Remodeling with Effects on Osteoblastic Lineage and Bone Mechanical Properties
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Journal Articles

Reply to the Letter to the Editor from Noopur Raje and Kenneth C. Anderson

Noopur Raje, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (24): 8321.
https://doi.org/10.1158/1078-0432.CCR-08-2278
Published: 15 December 2008
View article titled, Reply to the Letter to the Editor from Noopur Raje and Kenneth C. Anderson
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Journal Articles

Clinical, Radiographic, and Biochemical Characterization of Multiple Myeloma Patients with Osteonecrosis of the Jaw

Noopur Raje, Sook-Bin Woo, Karen Hande, Jeffrey T. Yap, Paul G. Richardson, Sonia Vallet, Nathaniel Treister, Teru Hideshima, Niall Sheehy, Shweta Chhetri, Brendan Connell, Wanling Xie, Yu-Tzu Tai, Agnieszka Szot-Barnes, Mei Tian, Robert L. Schlossman, Edie Weller, Nikhil C. Munshi, Annick D. Van Den Abbeele, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (8): 2387–2395.
https://doi.org/10.1158/1078-0432.CCR-07-1430
Published: 15 April 2008
View article titled, Clinical, Radiographic, and Biochemical Characterization of Multiple Myeloma Patients with Osteonecrosis of the Jaw
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Journal Articles

Neutralizing B-Cell–Activating Factor Antibody Improves Survival and Inhibits Osteoclastogenesis in a Severe Combined Immunodeficient Human Multiple Myeloma Model

Paola Neri, Shaji Kumar, Maria Teresa Fulciniti, Sonia Vallet, Shweta Chhetri, Sidhartha Mukherjee, YuTzu Tai, Dharminder Chauhan, Pierfrancesco Tassone, Salvatore Venuta, Nikhil C. Munshi, Teru Hideshima, Kenneth C. Anderson, Noopur Raje
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19): 5903–5909.
https://doi.org/10.1158/1078-0432.CCR-07-0753
Published: 01 October 2007
View article titled, Neutralizing B-Cell–Activating Factor Antibody Improves Survival and Inhibits Osteoclastogenesis in a Severe Combined Immunodeficient Human Multiple Myeloma Model
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Journal Articles

MLN120B, a Novel IκB Kinase β Inhibitor, Blocks Multiple Myeloma Cell Growth In vitro and In vivo

Teru Hideshima, Paola Neri, Pierfranchesco Tassone, Hiroshi Yasui, Kenji Ishitsuka, Noopur Raje, Dharminder Chauhan, Klaus Podar, Constantine Mitsiades, Lenny Dang, Nikhil Munshi, Paul Richardson, David Schenkein, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (19): 5887–5894.
https://doi.org/10.1158/1078-0432.CCR-05-2501
Published: 04 October 2006
View article titled, MLN120B, a Novel IκB Kinase β Inhibitor, Blocks Multiple Myeloma Cell Growth <em>In vitro</em> and <em>In vivo</em>
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Journal Articles

Characterization of Signaling Cascades Triggered by Human Interleukin-6 versus Kaposi’s Sarcoma-associated Herpes Virus-encoded Viral Interleukin 6

Teru Hideshima, Dharminder Chauhan, Gerrard Teoh, Noopur Raje, Steven P. Treon, Yu-Tzu Tai, Yoshihito Shima, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (3): 1180–1189.
Published: 01 March 2000
View article titled, Characterization of Signaling Cascades Triggered by Human Interleukin-6 <em>versus</em> Kaposi’s Sarcoma-associated Herpes Virus-encoded Viral Interleukin 6
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