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Journal Articles

Dose Escalation Data from the Phase 1 Study of the Liposomal Formulation of Eribulin (E7389-LF) in Japanese Patients with Advanced Solid Tumors

Jun Sato, Toshio Shimizu, Takafumi Koyama, Satoru Iwasa, Akihiko Shimomura, Shunsuke Kondo, Shigehisa Kitano, Kan Yonemori, Yutaka Fujiwara, Kenji Tamura, Takuya Suzuki, Takao Takase, Reiko Nagai, Kohei Yamaguchi, Taro Semba, Zi-Ming Zhao, Min Ren, Noboru Yamamoto

Clin Cancer Res (2022) 28 (9): 1783–1791.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-3518

Published: 02 May 2022

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Includes: Supplementary data

Journal Articles

Results from a First-in-Human Phase I Study of Siremadlin (HDM201) in Patients with Advanced Wild-Type TP53 Solid Tumors and Acute Leukemia

Clin Cancer Res (2022) 28 (5): 870–881.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-1295

Published: 03 March 2022

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Includes: Supplementary data

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TAS-116 (Pimitespib), an Oral HSP90 Inhibitor, in Combination with Nivolumab in Patients with Colorectal Cancer and Other Solid Tumors: An Open-Label, Dose-Finding, and Expansion Phase Ib Trial (EPOC1704)

Akihito Kawazoe, Kota Itahashi, Noboru Yamamoto, Daisuke Kotani, Yasutoshi Kuboki, Hiroya Taniguchi, Kenichi Harano, Yoichi Naito, Mitsuko Suzuki, Miki Fukutani, Tsukiko Higuchi, Takashi Ikeno, Masashi Wakabayashi, Akihiro Sato, Shohei Koyama, Hiroyoshi Nishikawa, Kohei Shitara

Clin Cancer Res (2021) 27 (24): 6709–6715.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-1929

Published: 15 December 2021

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Includes: Supplementary data

Journal Articles

Pharmacokinetics, Safety, and Efficacy of Trastuzumab Deruxtecan with Concomitant Ritonavir or Itraconazole in Patients with HER2-Expressing Advanced Solid Tumors

Shunji Takahashi, Masato Karayama, Masato Takahashi, Junichiro Watanabe, Hironobu Minami, Noboru Yamamoto, Ichiro Kinoshita, Chia-Chi Lin, Young-Hyuck Im, Issei Achiwa, Emi Kamiyama, Yasuyuki Okuda, Caleb Lee, Yung-Jue Bang

Clin Cancer Res (2021) 27 (21): 5771–5780.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-1560

Published: 01 November 2021

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Includes: Supplementary data

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First-in-Human Phase 1 Study of MORAb-202, an Antibody–Drug Conjugate Comprising Farletuzumab Linked to Eribulin Mesylate, in Patients with Folate Receptor-α–Positive Advanced Solid Tumors

Toshio Shimizu, Yutaka Fujiwara, Kan Yonemori, Takafumi Koyama, Jun Sato, Kenji Tamura, Akihiko Shimomura, Hiroki Ikezawa, Maiko Nomoto, Keiji Furuuchi, Ryo Nakajima, Takuma Miura, Noboru Yamamoto

Clin Cancer Res (2021) 27 (14): 3905–3915.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-4740

Published: 15 July 2021

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Includes: Supplementary data

Journal Articles

Blocking TIM-3 in Treatment-refractory Advanced Solid Tumors: A Phase Ia/b Study of LY3321367 with or without an Anti-PD-L1 Antibody

James J. Harding, Victor Moreno, Yung-Jue Bang, Min Hee Hong, Amita Patnaik, José Trigo, Anna M. Szpurka, Noboru Yamamoto, Toshihiko Doi, Siqing Fu, Boris Calderon, Nieves Velez de Mendizabal, Emiliano Calvo, Danni Yu, Leena Gandhi, Zhuqing Tina Liu, Violeta Regnier Galvao, Ching Ching Leow, Maria J. de Miguel

Clin Cancer Res (2021) 27 (8): 2168–2178.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-4405

Published: 15 April 2021

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Includes: Supplementary data

Journal Articles

A Phase I Study of the Anti-CC Chemokine Receptor 4 Antibody, Mogamulizumab, in Combination with Nivolumab in Patients with Advanced or Metastatic Solid Tumors

Toshihiko Doi, Kei Muro, Hiroshi Ishii, Terufumi Kato, Takahiro Tsushima, Mitsuhiro Takenoyama, Satoshi Oizumi, Kazuto Gemmoto, Hideaki Suna, Kouki Enokitani, Tetsuyoshi Kawakami, Hiroyoshi Nishikawa, Noboru Yamamoto

Clin Cancer Res (2019) 25 (22): 6614–6622.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-1090

Published: 15 November 2019

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Includes: Supplementary data

Journal Articles

Phase I Dose-Escalation Study and Biomarker Analysis of E7080 in Patients with Advanced Solid Tumors

Kazuhiko Yamada, Noboru Yamamoto, Yasuhide Yamada, Hiroshi Nokihara, Yutaka Fujiwara, Taizo Hirata, Fumiaki Koizumi, Kazuto Nishio, Noriyuki Koyama, Tomohide Tamura

Clin Cancer Res (2011) 17 (8): 2528–2537.

DOI: https://doi.org/10.1158/1078-0432.CCR-10-2638

Published: 14 April 2011

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Includes: Supplementary data

Journal Articles

Prospective Study of the Accuracy of EGFR Mutational Analysis by High-Resolution Melting Analysis in Small Samples Obtained from Patients with Non–Small Cell Lung Cancer

Tomoya Fukui, Yuichiro Ohe, Koji Tsuta, Koh Furuta, Hiromi Sakamoto, Toshimi Takano, Hiroshi Nokihara, Noboru Yamamoto, Ikuo Sekine, Hideo Kunitoh, Hisao Asamura, Takaaki Tsuchida, Masahiro Kaneko, Masahiko Kusumoto, Seiichiro Yamamoto, Teruhiko Yoshida, Tomohide Tamura

Clin Cancer Res (2008) 14 (15): 4751–4757.

DOI: https://doi.org/10.1158/1078-0432.CCR-07-5207

Published: 01 August 2008

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Journal Articles

Epidermal Growth Factor Receptor Mutation Detection Using High-Resolution Melting Analysis Predicts Outcomes in Patients with Advanced Non–Small Cell Lung Cancer Treated with Gefitinib

Toshimi Takano, Yuichiro Ohe, Koji Tsuta, Tomoya Fukui, Hiromi Sakamoto, Teruhiko Yoshida, Ukihide Tateishi, Hiroshi Nokihara, Noboru Yamamoto, Ikuo Sekine, Hideo Kunitoh, Yoshihiro Matsuno, Koh Furuta, Tomohide Tamura

Clin Cancer Res (2007) 13 (18): 5385–5390.

DOI: https://doi.org/10.1158/1078-0432.CCR-07-0627

Published: 17 September 2007

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Journal Articles

Severe Drug Toxicity Associated with a Single-Nucleotide Polymorphism of the Cytidine Deaminase Gene in a Japanese Cancer Patient Treated with Gemcitabine plus Cisplatin

Kan Yonemori, Hideki Ueno, Takuji Okusaka, Noboru Yamamoto, Masafumi Ikeda, Nagahiro Saijo, Teruhiko Yoshida, Hiroshi Ishii, Junji Furuse, Emiko Sugiyama, Su-Ryang Kim, Ruri Kikura-Hanajiri, Ryuichi Hasegawa, Yoshiro Saito, Shogo Ozawa, Nahoko Kaniwa, Jun-ichi Sawada

Clin Cancer Res (2005) 11 (7): 2620–2624.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-1497

Published: 06 April 2005

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NARROW

Dose Escalation Data from the Phase 1 Study of the Liposomal Formulation of Eribulin (E7389-LF) in Japanese Patients with Advanced Solid Tumors

Results from a First-in-Human Phase I Study of Siremadlin (HDM201) in Patients with Advanced Wild-Type TP53 Solid Tumors and Acute Leukemia

TAS-116 (Pimitespib), an Oral HSP90 Inhibitor, in Combination with Nivolumab in Patients with Colorectal Cancer and Other Solid Tumors: An Open-Label, Dose-Finding, and Expansion Phase Ib Trial (EPOC1704)

Pharmacokinetics, Safety, and Efficacy of Trastuzumab Deruxtecan with Concomitant Ritonavir or Itraconazole in Patients with HER2-Expressing Advanced Solid Tumors

First-in-Human Phase 1 Study of MORAb-202, an Antibody–Drug Conjugate Comprising Farletuzumab Linked to Eribulin Mesylate, in Patients with Folate Receptor-α–Positive Advanced Solid Tumors

Blocking TIM-3 in Treatment-refractory Advanced Solid Tumors: A Phase Ia/b Study of LY3321367 with or without an Anti-PD-L1 Antibody

A Phase I Study of the Anti-CC Chemokine Receptor 4 Antibody, Mogamulizumab, in Combination with Nivolumab in Patients with Advanced or Metastatic Solid Tumors

Phase I Dose-Escalation Study and Biomarker Analysis of E7080 in Patients with Advanced Solid Tumors

Prospective Study of the Accuracy of EGFR Mutational Analysis by High-Resolution Melting Analysis in Small Samples Obtained from Patients with Non–Small Cell Lung Cancer

Epidermal Growth Factor Receptor Mutation Detection Using High-Resolution Melting Analysis Predicts Outcomes in Patients with Advanced Non–Small Cell Lung Cancer Treated with Gefitinib

Severe Drug Toxicity Associated with a Single-Nucleotide Polymorphism of the Cytidine Deaminase Gene in a Japanese Cancer Patient Treated with Gemcitabine plus Cisplatin

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