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Journal Articles

Platinum-Based Chemotherapy Induces Opposing Effects on Immunotherapy Response-Related Spatial and Stromal Biomarkers in the Bladder Cancer Microenvironment

Maksim A. Chelushkin, Jeroen van Dorp, Sandra van Wilpe, Iris M. Seignette, Jan-Jaap J. Mellema, Maartje Alkemade, Alberto Gil-Jimenez, Dennis Peters, Wim Brugman, Chantal F. Stockem, Erik Hooijberg, Annegien Broeks, Bas W.G. van Rhijn, Laura S. Mertens, Antoine G. van der Heijden, Niven Mehra, Maurits L. van Montfoort, Lodewyk F.A. Wessels, Daniel J. Vis, Michiel S. van der Heijden
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (18): 4227–4239.
https://doi.org/10.1158/1078-0432.CCR-24-0724
Published: 13 September 2024
View article titled, Platinum-Based Chemotherapy Induces Opposing Effects on Immunotherapy Response-Related Spatial and Stromal Biomarkers in the Bladder Cancer Microenvironment
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Includes: Supplementary data
Journal Articles

Early On-treatment Changes in Circulating Tumor DNA Fraction and Response to Enzalutamide or Abiraterone in Metastatic Castration-Resistant Prostate Cancer

Sofie H. Tolmeijer, Emmy Boerrigter, Takayuki Sumiyoshi, Edmond M. Kwan, Sarah W.S. Ng, Matti Annala, Gráinne Donnellan, Cameron Herberts, Guillemette E. Benoist, Paul Hamberg, Diederik M. Somford, Inge M. van Oort, Jack A. Schalken, Niven Mehra, Nielka P. van Erp, Alexander W. Wyatt
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (15): 2835–2844.
https://doi.org/10.1158/1078-0432.CCR-22-2998
Published: 01 August 2023
View article titled, Early On-treatment Changes in Circulating Tumor DNA Fraction and Response to Enzalutamide or Abiraterone in Metastatic Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Tumor Genomic Testing for >4,000 Men with Metastatic Castration-resistant Prostate Cancer in the Phase III Trial PROfound (Olaparib)

Maha Hussain, Claire Corcoran, Caroline Sibilla, Karim Fizazi, Fred Saad, Neal Shore, Shahneen Sandhu, Joaquin Mateo, David Olmos, Niven Mehra, Michael P. Kolinsky, Guilhem Roubaud, Mustafa Özgüroǧlu, Nobuaki Matsubara, Craig Gedye, Young Deuk Choi, Charles Padua, Alexander Kohlmann, Robert Huisden, Julia A. Elvin, Jinyu Kang, Carrie A. Adelman, Allison Allen, Christian Poehlein, Johann de Bono
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (8): 1518–1530.
https://doi.org/10.1158/1078-0432.CCR-21-3940
Published: 14 April 2022
View article titled, Tumor Genomic Testing for >4,000 Men with Metastatic Castration-resistant Prostate Cancer in the Phase III Trial PROfound (Olaparib)
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Includes: Supplementary data
Journal Articles

Patients with Biallelic BRCA1/2 Inactivation Respond to Olaparib Treatment Across Histologic Tumor Types

Hanneke van der Wijngaart, Louisa R. Hoes, J. Maxime van Berge Henegouwen, Daphne L. van der Velden, Laurien J. Zeverijn, Paul Roepman, Erik van Werkhoven, Wendy W.J. de Leng, Anne M.L. Jansen, Niven Mehra, Debbie G.J. Robbrecht, Mariette Labots, Derk Jan A. de Groot, Ann Hoeben, Paul Hamberg, Hans Gelderblom, Emile E. Voest, Henk M.W. Verheul
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (22): 6106–6114.
https://doi.org/10.1158/1078-0432.CCR-21-1104
Published: 15 November 2021
View article titled, Patients with Biallelic BRCA1/2 Inactivation Respond to Olaparib Treatment Across Histologic Tumor Types
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Includes: Supplementary data
Journal Articles

Lutetium-177-PSMA-617 in Low-Volume Hormone-Sensitive Metastatic Prostate Cancer: A Prospective Pilot Study

Bastiaan M. Privé, Steffie M.B. Peters, Constantijn H.J. Muselaers, Inge M. van Oort, Marcel J.R. Janssen, J.P. Michiel Sedelaar, Mark W. Konijnenberg, Patrik Zámecnik, Maike J.M. Uijen, Melline G.M. Schilham, Annemarie Eek, Tom W.J. Scheenen, J. Fred Verzijlbergen, Winald R. Gerritsen, Niven Mehra, Linda G.W. Kerkmeijer, Robert J. Smeenk, Diederik M. Somford, Jean-Paul A. van Basten, Sandra Heskamp, Jelle O. Barentsz, Martin Gotthardt, J. Alfred Witjes, James Nagarajah
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (13): 3595–3601.
https://doi.org/10.1158/1078-0432.CCR-20-4298
Published: 01 July 2021
View article titled, Lutetium-177-PSMA-617 in Low-Volume Hormone-Sensitive Metastatic Prostate Cancer: A Prospective Pilot Study
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Includes: Supplementary data
Journal Articles

Single-Cell Analyses of Prostate Cancer Liquid Biopsies Acquired by Apheresis

Maryou B. Lambros, George Seed, Semini Sumanasuriya, Veronica Gil, Mateus Crespo, Mariane Fontes, Rob Chandler, Niven Mehra, Gemma Fowler, Berni Ebbs, Penny Flohr, Susana Miranda, Wei Yuan, Alan Mackay, Ana Ferreira, Rita Pereira, Claudia Bertan, Ines Figueiredo, Ruth Riisnaes, Daniel Nava Rodrigues, Adam Sharp, Jane Goodall, Gunther Boysen, Suzanne Carreira, Diletta Bianchini, Pasquale Rescigno, Zafeiris Zafeiriou, Joanne Hunt, Deirdre Moloney, Lucy Hamilton, Rui P. Neves, Joost Swennenhuis, Kiki Andree, Nikolas H. Stoecklein, Leon W.M.M. Terstappen, Johann S. de Bono
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (22): 5635–5644.
https://doi.org/10.1158/1078-0432.CCR-18-0862
Published: 15 November 2018
View article titled, Single-Cell Analyses of Prostate Cancer Liquid Biopsies Acquired by Apheresis
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Includes: Supplementary data
Journal Articles

CCR 20th Anniversary Commentary: Circulating Tumor Cells in Prostate Cancer

Niven Mehra, Zafeiris Zafeiriou, David Lorente, Leon W.M.M. Terstappen, Johann S. de Bono
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (22): 4992–4995.
https://doi.org/10.1158/1078-0432.CCR-14-3129
Published: 12 November 2015
View article titled, <em>CCR</em> 20<sup>th</sup> Anniversary Commentary: Circulating Tumor Cells in Prostate Cancer
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Journal Articles

Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C β-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer

Jeany M. Rademaker-Lakhai, Laurens V. Beerepoot, Niven Mehra, Sandra A. Radema, Rianne van Maanen, Joost S. Vermaat, Els O. Witteveen, Carla M. Visseren-Grul, Luna Musib, Nathan Enas, Gertjan van Hal, Jos H. Beijnen, Jan H.M. Schellens, Emile E. Voest
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (15): 4474–4481.
https://doi.org/10.1158/1078-0432.CCR-06-2912
Published: 01 August 2007
View article titled, Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C β-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer
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Journal Articles

Circulating Mitochondrial Nucleic Acids Have Prognostic Value for Survival in Patients with Advanced Prostate Cancer

Niven Mehra, Maarten Penning, Jolanda Maas, Nancy van Daal, Rachel H. Giles, Emile E. Voest
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (2): 421–426.
https://doi.org/10.1158/1078-0432.CCR-06-1087
Published: 25 January 2007
View article titled, Circulating Mitochondrial Nucleic Acids Have Prognostic Value for Survival in Patients with Advanced Prostate Cancer
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Journal Articles

Progenitor Marker CD133 mRNA Is Elevated in Peripheral Blood of Cancer Patients with Bone Metastases

Niven Mehra, Maarten Penning, Jolanda Maas, Laurens V. Beerepoot, Nancy van Daal, Carla H. van Gils, Rachel H. Giles, Emile E. Voest
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (16): 4859–4866.
https://doi.org/10.1158/1078-0432.CCR-06-0422
Published: 16 August 2006
View article titled, Progenitor Marker CD133 mRNA Is Elevated in Peripheral Blood of Cancer Patients with Bone Metastases
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