1-20 of 35
Nikolaus Schultz
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

A Phase II Study Assessing Long-term Response to Ibrutinib Monotherapy in Recurrent or Refractory CNS Lymphoma

Christian Grommes, Subhiksha Nandakumar, Lauren R. Schaff, Igor Gavrilovic, Thomas J. Kaley, Craig P. Nolan, Jacqueline Stone, Alissa A. Thomas, Sarah S. Tang, Julia Wolfe, Alexis Bozza, Venissala Wongchai, Alisson Hyde, Emma Barrett, Elizabeth A. Lynch, Juli T. Madzsar, Andrew Lin, Anna F. Piotrowski, Elena Pentsova, Jasmine H. Francis, Vaios Hatzoglou, Nikolaus Schultz, Anne S. Reiner, Katherine S. Panageas, Lisa M. DeAngelis, Ingo K. Mellinghoff
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (18): 4005–4015.
https://doi.org/10.1158/1078-0432.CCR-24-0605
Published: 13 September 2024
View article titled, A Phase II Study Assessing Long-term Response to Ibrutinib Monotherapy in Recurrent or Refractory CNS Lymphoma
Open the PDF for A Phase II Study Assessing Long-term Response to Ibrutinib Monotherapy in Recurrent or Refractory CNS Lymphoma in another window
Includes: Supplementary data
Journal Articles

Multiplexed Spatial Profiling of Hodgkin Reed–Sternberg Cell Neighborhoods in Classic Hodgkin Lymphoma

Maryam Pourmaleki, Caitlin J. Jones, Sabrina D. Mellinghoff, Brian D. Greenstein, Priyadarshini Kumar, Miguel Foronda, Daniel A. Navarrete, Carl Campos, Mikhail Roshal, Nikolaus Schultz, Sohrab P. Shah, Andrea Schietinger, Nicholas D. Socci, Travis J. Hollmann, Ahmet Dogan, Ingo K. Mellinghoff
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (17): 3881–3893.
https://doi.org/10.1158/1078-0432.CCR-24-0942
Published: 03 September 2024
View article titled, Multiplexed Spatial Profiling of Hodgkin Reed–Sternberg Cell Neighborhoods in Classic Hodgkin Lymphoma
Open the PDF for Multiplexed Spatial Profiling of Hodgkin Reed–Sternberg Cell Neighborhoods in Classic Hodgkin Lymphoma in another window
Includes: Supplementary data
Journal Articles

Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer

Andrew T. Lenis, Vignesh Ravichandran, Samantha Brown, Syed M. Alam, Andrew Katims, Hong Truong, Peter A. Reisz, Samantha Vasselman, Barbara Nweji, Karen A. Autio, Michael J. Morris, Susan F. Slovin, Dana Rathkopf, Daniel Danila, Sungmin Woo, Hebert A. Vargas, Vincent P. Laudone, Behfar Ehdaie, Victor Reuter, Maria Arcila, Michael F. Berger, Agnes Viale, Howard I. Scher, Nikolaus Schultz, Anuradha Gopalan, Mark T.A. Donoghue, Irina Ostrovnaya, Konrad H. Stopsack, David B. Solit, Wassim Abida
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (17): 3894–3903.
https://doi.org/10.1158/1078-0432.CCR-23-3403
Published: 03 September 2024
View article titled, Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer
Open the PDF for Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

A Novel Approach to Quantify Heterogeneity of Intrahepatic Cholangiocarcinoma: The Hidden-Genome Classifier

Yi Song, Thomas Boerner, Esther Drill, Paul Shin, Sandeep Kumar, Carlie Sigel, Andrea Cercek, Nancy Kemeny, Ghassan Abou-Alfa, Christine Iacobuzio-Donahue, Darren Cowzer, Nikolaus Schultz, Henry Walch, Vinod Balachandran, Bas Groot Koerkamp, Peter Kingham, Kevin Soares, Alice Wei, Michael D’Angelica, Jeffrey Drebin, Rohit Chandwani, James J. Harding, William Jarnagin
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (16): 3499–3511.
https://doi.org/10.1158/1078-0432.CCR-24-0657
Published: 15 August 2024
View article titled, A Novel Approach to Quantify Heterogeneity of Intrahepatic Cholangiocarcinoma: The Hidden-Genome Classifier
Open the PDF for A Novel Approach to Quantify Heterogeneity of Intrahepatic Cholangiocarcinoma: The Hidden-Genome Classifier in another window
Includes: Supplementary data
Journal Articles

Molecular and Clinical Determinants of Acquired Resistance and Treatment Duration for Targeted Therapies in Colorectal Cancer

Emily Harrold, Fergus Keane, Henry Walch, Joanne F. Chou, Jenna Sinopoli, Silvia Palladino, Duaa H. Al-Rawi, Kalyani Chadalavada, Paolo Manca, Sree Chalasani, Jessica Yang, Andrea Cercek, Jinru Shia, Marinela Capanu, Samuel F. Bakhoum, Nikolaus Schultz, Walid K. Chatila, Rona Yaeger
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (12): 2672–2683.
https://doi.org/10.1158/1078-0432.CCR-23-4005
Published: 14 June 2024
View article titled, Molecular and Clinical Determinants of Acquired Resistance and Treatment Duration for Targeted Therapies in Colorectal Cancer
Open the PDF for Molecular and Clinical Determinants of Acquired Resistance and Treatment Duration for Targeted Therapies in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Integrative Molecular Analyses of the MD Anderson Prostate Cancer Patient-derived Xenograft (MDA PCa PDX) Series

Nicolas Anselmino, Estefania Labanca, Peter D.A. Shepherd, Jiabin Dong, Jun Yang, Xiaofei Song, Subhiksha Nandakumar, Ritika Kundra, Cindy Lee, Nikolaus Schultz, Jianhua Zhang, John C. Araujo, Ana M. Aparicio, Sumit K. Subudhi, Paul G. Corn, Louis L. Pisters, John F. Ward, John W. Davis, Elba S. Vazquez, Geraldine Gueron, Christopher J. Logothetis, Andrew Futreal, Patricia Troncoso, Yu Chen, Nora M. Navone
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (10): 2272–2285.
https://doi.org/10.1158/1078-0432.CCR-23-2438
Published: 15 May 2024
View article titled, Integrative Molecular Analyses of the MD Anderson Prostate Cancer Patient-derived Xenograft (MDA PCa PDX) Series
Open the PDF for Integrative Molecular Analyses of the MD Anderson Prostate Cancer Patient-derived Xenograft (MDA PCa PDX) Series in another window
Includes: Supplementary data
Journal Articles

Determinants of Survival with Combined HER2 and PD-1 Blockade in Metastatic Esophagogastric Cancer

Steven B. Maron, Walid Chatila, Henry Walch, Joanne F. Chou, Nicholas Ceglia, Ryan Ptashkin, Richard Kinh Gian Do, Viktoriya Paroder, Neeta Pandit-Taskar, Jason S. Lewis, Tiago Biachi De Castria, Shalom Sabwa, Fiona Socolow, Lara Feder, Jasmine Thomas, Isabell Schulze, Kwanghee Kim, Arijh Elzein, Viktoria Bojilova, Matthew Zatzman, Umesh Bhanot, Rebecca J. Nagy, Jeeyun Lee, Marc Simmons, Michal Segal, Geoffrey Yuyat Ku, David H. Ilson, Marinela Capanu, Jaclyn F. Hechtman, Taha Merghoub, Sohrab Shah, Nikolaus Schultz, David B. Solit, Yelena Y. Janjigian
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (18): 3633–3640.
https://doi.org/10.1158/1078-0432.CCR-22-3769
Published: 15 September 2023
View article titled, Determinants of Survival with Combined HER2 and PD-1 Blockade in Metastatic Esophagogastric Cancer
Open the PDF for Determinants of Survival with Combined HER2 and PD-1 Blockade in Metastatic Esophagogastric Cancer in another window
Includes: Supplementary data
Journal Articles

The GENIE BPC NSCLC Cohort: A Real-World Repository Integrating Standardized Clinical and Genomic Data for 1,846 Patients with Non–Small Cell Lung Cancer

Noura J. Choudhury, Jessica A. Lavery, Samantha Brown, Ino de Bruijn, Justin Jee, Thinh Ngoc Tran, Hira Rizvi, Kathryn C. Arbour, Karissa Whiting, Ronglai Shen, Matthew Hellmann, Philippe L. Bedard, Celeste Yu, Natasha Leighl, Michele LeNoue-Newton, Christine Micheel, Jeremy L. Warner, Michelle S. Ginsberg, Andrew Plodkowski, Jeffrey Girshman, Peter Sawan, Shirin Pillai, Shawn M. Sweeney, Kenneth L. Kehl, Katherine S. Panageas, Nikolaus Schultz, Deborah Schrag, Gregory J. Riely, on behalf of the AACR GENIE BPC Core Team
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (17): 3418–3428.
https://doi.org/10.1158/1078-0432.CCR-23-0580
Published: 01 September 2023
View article titled, The GENIE BPC NSCLC Cohort: A Real-World Repository Integrating Standardized Clinical and Genomic Data for 1,846 Patients with Non–Small Cell Lung Cancer
Open the PDF for The GENIE BPC NSCLC Cohort: A Real-World Repository Integrating Standardized Clinical and Genomic Data for 1,846 Patients with Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

The Impact of Germline Alterations in Appendiceal Adenocarcinoma

Michael B. Foote, Henry Walch, Yelena Kemel, Efsevia Vakiani, Paul Johannet, Margaret Sheehan, Walid Chatila, Sebastian Chung, Garrett M. Nash, Anna Maio, Jinru Shia, Diana Mandelker, Michael Berger, Nikolaus Schultz, Luis A. Diaz, Andrea Cercek, Zsofia K. Stadler
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (14): 2631–2637.
https://doi.org/10.1158/1078-0432.CCR-22-3956
Published: 14 July 2023
View article titled, The Impact of Germline Alterations in Appendiceal Adenocarcinoma
Open the PDF for The Impact of Germline Alterations in Appendiceal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention

Nicolas A. Giraldo, Esther Drill, Baby A. Satravada, Imane El Dika, A. Rose Brannon, Josephine Dermawan, Abhinita Mohanty, Kerem Ozcan, Debyani Chakravarty, Ryma Benayed, Efsevia Vakiani, Ghassan K. Abou-Alfa, Ritika Kundra, Nikolaus Schultz, Bob T. Li, Michael F. Berger, James J. Harding, Marc Ladanyi, Eileen M. O'Reilly, William Jarnagin, Chad Vanderbilt, Olca Basturk, Maria E. Arcila
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (24): 5359–5367.
https://doi.org/10.1158/1078-0432.CCR-22-1954
Published: 15 December 2022
View article titled, Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention
Open the PDF for Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention in another window
Includes: Supplementary data
Journal Articles

Abstract PR012: Targeted sequencing of 2,138 bone and soft tissue sarcomas reveals commonly altered pathways, subtype-independent genetic clusters, and potential therapeutic targets

Benjamin A. Nacev, Francisco Sanchez-Vega, Shaleigh Smith, Cristina Antonescu, Evan Rosenbaum, Hongyu Shi, Cerise Tang, Nicholas Socci, Satshil Rana, Rodrigo Gularte-Merida, Ahmet Zehir, Mrinal Gounder, Timothy Bowler, Anisha Luthra, Bhumika Jadeja, Azusa Okada, Jonathan Strong, Jake Stoller, Jason Chan, Ping Chi, Sandra D'Angelo, Mark Dickson, Ciara Kelly, Mary Louise Keohan, Sujana Movva, Katherine Thornton, Paul Meyers, Leonard Wexler, Emily Slotkin, Julia Glade Bender, Neerav Shukla, Martee Hensley, John Healey, Michael La Quaglia, Kaled Alektiar, Aimee Crago, Sam Yoon, Brian Untch, Sarah Chiang, Narasimhan Agaram, Meera Hameed, Michael Berger, David Solit, Nikolaus Schultz, Marc Ladanyi, Samuel Singer, William Tap
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18_Supplement): PR012.
https://doi.org/10.1158/1557-3265.SARCOMAS22-PR012
Published: 15 September 2022
View article titled, Abstract PR012: Targeted sequencing of 2,138 bone and soft tissue sarcomas reveals commonly altered pathways, subtype-independent genetic clusters, and potential therapeutic targets
Journal Articles

The Impact of PIK3R1 Mutations and Insulin–PI3K–Glycolytic Pathway Regulation in Prostate Cancer

Goutam Chakraborty, Subhiksha Nandakumar, Rahim Hirani, Bastien Nguyen, Konrad H. Stopsack, Christoph Kreitzer, Sai Harisha Rajanala, Romina Ghale, Ying Z. Mazzu, Naga Vara Kishore Pillarsetty, Gwo-Shu Mary Lee, Howard I. Scher, Michael J. Morris, Tiffany Traina, Pedram Razavi, Wassim Abida, Jeremy C. Durack, Stephen B. Solomon, Matthew G. Vander Heiden, Lorelei A. Mucci, Andreas G. Wibmer, Nikolaus Schultz, Philip W. Kantoff
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (16): 3603–3617.
https://doi.org/10.1158/1078-0432.CCR-21-4272
Published: 15 August 2022
View article titled, The Impact of PIK3R1 Mutations and Insulin–PI3K–Glycolytic Pathway Regulation in Prostate Cancer
Open the PDF for The Impact of PIK3R1 Mutations and Insulin–PI3K–Glycolytic Pathway Regulation in Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

The Role of the TP53 Pathway in Predicting Response to Neoadjuvant Therapy in Esophageal Adenocarcinoma

Smita Sihag, Samuel C. Nussenzweig, Henry S. Walch, Meier Hsu, Kay See Tan, Sergio De La Torre, Yelena Y. Janjigian, Steven B. Maron, Geoffrey Y. Ku, Laura H. Tang, Pari M. Shah, Abraham Wu, David R. Jones, David B. Solit, Nikolaus Schultz, Karuna Ganesh, Michael F. Berger, Daniela Molena
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (12): 2669–2678.
https://doi.org/10.1158/1078-0432.CCR-21-4016
Published: 13 June 2022
View article titled, The Role of the TP53 Pathway in Predicting Response to Neoadjuvant Therapy in Esophageal Adenocarcinoma
Open the PDF for The Role of the TP53 Pathway in Predicting Response to Neoadjuvant Therapy in Esophageal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors

Konrad H. Stopsack, Subhiksha Nandakumar, Kanika Arora, Bastien Nguyen, Samantha E. Vasselman, Barbara Nweji, Sean M. McBride, Michael J. Morris, Dana E. Rathkopf, Susan F. Slovin, Daniel C. Danila, Karen A. Autio, Howard I. Scher, Lorelei A. Mucci, David B. Solit, Mithat Gönen, Yu Chen, Michael F. Berger, Nikolaus Schultz, Wassim Abida, Philip W. Kantoff
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (2): 318–326.
https://doi.org/10.1158/1078-0432.CCR-21-2577
Published: 15 January 2022
View article titled, Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors
Open the PDF for Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors in another window
Includes: Supplementary data
Journal Articles

Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways

Smita Sihag, Samuel C. Nussenzweig, Henry S. Walch, Meier Hsu, Kay See Tan, Francisco Sanchez-Vega, Walid K. Chatila, Sergio A. De La Torre, Assem Patel, Yelena Y. Janjigian, Steven Maron, Geoffrey Y. Ku, Laura H. Tang, Jaclyn Hechtman, Pari M. Shah, Abraham J. Wu, David R. Jones, Daniela Molena, David B. Solit, Nikolaus Schultz, Michael F. Berger
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (12): 3491–3498.
https://doi.org/10.1158/1078-0432.CCR-20-4707
Published: 15 June 2021
View article titled, Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways
Open the PDF for Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways in another window
Includes: Supplementary data
Journal Articles

Therapeutic Implications of Detecting MAPK-Activating Alterations in Cutaneous and Unknown Primary Melanomas

Alexander N. Shoushtari, Walid K. Chatila, Arshi Arora, Francisco Sanchez-Vega, Havish S. Kantheti, Jorge A. Rojas Zamalloa, Penina Krieger, Margaret K. Callahan, Allison Betof Warner, Michael A. Postow, Parisa Momtaz, Suresh Nair, Charlotte E. Ariyan, Christopher A. Barker, Mary Susan Brady, Daniel G. Coit, Neal Rosen, Paul B. Chapman, Klaus J. Busam, David B. Solit, Katherine S. Panageas, Jedd D. Wolchok, Nikolaus Schultz
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8): 2226–2235.
https://doi.org/10.1158/1078-0432.CCR-20-4189
Published: 15 April 2021
View article titled, Therapeutic Implications of Detecting MAPK-Activating Alterations in Cutaneous and Unknown Primary Melanomas
Open the PDF for Therapeutic Implications of Detecting MAPK-Activating Alterations in Cutaneous and Unknown Primary Melanomas in another window
Includes: Supplementary data
Journal Articles

Abstract A14: Next-generation sequencing of Bacille Calmette-Guerin (BCG)-unresponsive tumors identifies actionable alterations for potential targeted therapy in non-muscle invasive bladder cancer

Aleksandra Walasek, Nima Almassi, Victor McPherson, Shawn Dason, Nicole Benfante, Tanya Klein, Michael F. Berger, Nikolaus Schultz, Guido Dalbagni, Dean F. Bajorin, Jonathan E. Rosenberg, Hikmat Al-Ahmadie, Bernard H. Bochner, David B. Solit, Gopakumar Iyer, Eugene J. Pietzak
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (15_Supplement): A14.
https://doi.org/10.1158/1557-3265.BLADDER19-A14
Published: 03 August 2020
View article titled, Abstract A14: Next-generation sequencing of Bacille Calmette-Guerin (BCG)-unresponsive tumors identifies actionable alterations for potential targeted therapy in non-muscle invasive bladder cancer
Journal Articles

Abstract B20: Characterization of tumor mutational landscape in smokers and nonsmokers with urothelial carcinoma

Aleksandra Walasek, Nima Almassi, Min Yuen Teo, Samuel Funt, Nikolaus Schultz, Guido Dalbagni, Wenhu Hu, Hikmat Al-Ahmadie, Dean F Bajorin, Jonathan E Rosenberg, Gopakumar Iyer, Bernard H. Bochner, David B. Solit, Eugene J. Pietzak
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (15_Supplement): B20.
https://doi.org/10.1158/1557-3265.BLADDER19-B20
Published: 03 August 2020
View article titled, Abstract B20: Characterization of tumor mutational landscape in smokers and nonsmokers with urothelial carcinoma
Journal Articles

Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection

Wungki Park, Jiapeng Chen, Joanne F. Chou, Anna M. Varghese, Kenneth H. Yu, Winston Wong, Marinela Capanu, Vinod Balachandran, Caitlin A. McIntyre, Imane El Dika, Danny N. Khalil, James J. Harding, Nima Ghalehsari, Zoe McKinnell, Sree B. Chalasani, Vladimir Makarov, Pier Selenica, Xin Pei, Nicolas Lecomte, David P. Kelsen, Ghassan K. Abou-Alfa, Mark E. Robson, Liying Zhang, Michael F. Berger, Nikolaus Schultz, Timothy A. Chan, Simon N. Powell, Jorge S. Reis-Filho, Christine A. Iacobuzio-Donahue, Nadeem Riaz, Eileen M. O'Reilly
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (13): 3239–3247.
https://doi.org/10.1158/1078-0432.CCR-20-0418
Published: 01 July 2020
View article titled, Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection
Open the PDF for Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection in another window
Includes: Supplementary data
Journal Articles

Mismatch Repair–Deficient Rectal Cancer and Resistance to Neoadjuvant Chemotherapy

Andrea Cercek, Gustavo Dos Santos Fernandes, Campbell S. Roxburgh, Karuna Ganesh, Shu Ng, Francisco Sanchez-Vega, Rona Yaeger, Neil H. Segal, Diane L. Reidy-Lagunes, Anna M. Varghese, Arnold Markowitz, Chao Wu, Bryan Szeglin, Charles-Etienne Gabriel Sauvé, Erin Salo-Mullen, Christina Tran, Zalak Patel, Asha Krishnan, Kaitlyn Tkachuk, Garrett M. Nash, Jose Guillem, Philip B. Paty, Jinru Shia, Nikolaus Schultz, Julio Garcia-Aguilar, Luis A. Diaz, Karyn Goodman, Leonard B. Saltz, Martin R. Weiser, J. Joshua Smith, Zsofia K. Stadler
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (13): 3271–3279.
https://doi.org/10.1158/1078-0432.CCR-19-3728
Published: 01 July 2020
View article titled, Mismatch Repair–Deficient Rectal Cancer and Resistance to Neoadjuvant Chemotherapy
Open the PDF for Mismatch Repair–Deficient Rectal Cancer and Resistance to Neoadjuvant Chemotherapy in another window
Includes: Supplementary data