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Nikhil Wagle
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Journal Articles

Research Silos in Cancer Disparities: Obstacles to Improving Clinical Outcomes for Underserved Patient Populations

Available to Purchase
Angelique Richardson, Burcu Darst, Genevieve Wojcik, Nikhil Wagle, Svasti Haricharan
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (7): 1194–1199.
https://doi.org/10.1158/1078-0432.CCR-22-3182
Published: 03 April 2023
View article titled, Research Silos in Cancer Disparities: Obstacles to Improving Clinical Outcomes for Underserved Patient Populations
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Journal Articles

Somatic and Germline Genomic Alterations in Very Young Women with Breast Cancer

Open Access
Adrienne G. Waks, Dewey Kim, Esha Jain, Craig Snow, Gregory J. Kirkner, Shoshana M. Rosenberg, Coyin Oh, Philip D. Poorvu, Kathryn J. Ruddy, Rulla M. Tamimi, Jeffrey Peppercorn, Lidia Schapira, Virginia F. Borges, Steven E. Come, Elena F. Brachtel, Ellen Warner, Laura C. Collins, Ann H. Partridge, Nikhil Wagle
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (11): 2339–2348.
https://doi.org/10.1158/1078-0432.CCR-21-2572
Published: 01 June 2022
View article titled, Somatic and Germline Genomic Alterations in Very Young Women with Breast Cancer
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Includes: Supplementary data
Journal Articles

Genomic Characterization of de novo Metastatic Breast Cancer

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Ana C. Garrido-Castro, Liam F. Spurr, Melissa E. Hughes, Yvonne Y. Li, Andrew D. Cherniack, Priti Kumari, Maxwell R. Lloyd, Brittany Bychkovsky, Romualdo Barroso-Sousa, Simona Di Lascio, Esha Jain, Janet Files, Ayesha Mohammed-Abreu, Max Krevalin, Colin MacKichan, William T. Barry, Hao Guo, Daniel Xia, Ethan Cerami, Barrett J. Rollins, Laura E. MacConaill, Neal I. Lindeman, Ian E. Krop, Bruce E. Johnson, Nikhil Wagle, Eric P. Winer, Deborah A. Dillon, Nancy U. Lin
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (4): 1105–1118.
https://doi.org/10.1158/1078-0432.CCR-20-1720
Published: 15 February 2021
View article titled, Genomic Characterization of de novo Metastatic Breast Cancer
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Includes: Supplementary data
Journal Articles

Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer

Free
Pingping Mao, Ofir Cohen, Kailey J. Kowalski, Justin G. Kusiel, Jorge E. Buendia-Buendia, Michael S. Cuoco, Pedro Exman, Seth A. Wander, Adrienne G. Waks, Utthara Nayar, Jon Chung, Samuel Freeman, Orit Rozenblatt-Rosen, Vincent A. Miller, Federica Piccioni, David E. Root, Aviv Regev, Eric P. Winer, Nancy U. Lin, Nikhil Wagle
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (22): 5974–5989.
https://doi.org/10.1158/1078-0432.CCR-19-3958
Published: 13 November 2020
View article titled, Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer
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Includes: Supplementary data
Journal Articles

Identification of a RAS-activating TMEM87A–RASGRF1 Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer

Available to Purchase
Alissa J. Cooper, Yoshihisa Kobayashi, Dewey Kim, Sarah E. Clifford, Sasha Kravets, Suzanne E. Dahlberg, Emily S. Chambers, Jiaqi Li, Deepa Rangachari, Tom Nguyen, Daniel B. Costa, Michael S. Rabin, Nikhil Wagle, Lynette M. Sholl, Pasi A Jänne, Geoffrey R. Oxnard
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (15): 4072–4079.
https://doi.org/10.1158/1078-0432.CCR-20-0397
Published: 03 August 2020
View article titled, Identification of a RAS-activating TMEM87A–RASGRF1 Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer

Free
Heather A. Parsons, Justin Rhoades, Sarah C. Reed, Gregory Gydush, Priyanka Ram, Pedro Exman, Kan Xiong, Christopher C. Lo, Tianyu Li, Mark Fleharty, Gregory J. Kirkner, Denisse Rotem, Ofir Cohen, Fangyan Yu, Mariana Fitarelli-Kiehl, Ka Wai Leong, Melissa E. Hughes, Shoshana M. Rosenberg, Laura C. Collins, Kathy D. Miller, Brendan Blumenstiel, Lorenzo Trippa, Carrie Cibulskis, Donna S. Neuberg, Matthew DeFelice, Samuel S. Freeman, Niall J. Lennon, Nikhil Wagle, Gavin Ha, Daniel G. Stover, Atish D. Choudhury, Gad Getz, Eric P. Winer, Matthew Meyerson, Nancy U. Lin, Ian Krop, J. Christopher Love, G. Mike Makrigiorgos, Ann H. Partridge, Erica L. Mayer, Todd R. Golub, Viktor A. Adalsteinsson
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (11): 2556–2564.
https://doi.org/10.1158/1078-0432.CCR-19-3005
Published: 01 June 2020
View article titled, Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
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Includes: Supplementary data
Journal Articles

Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer

Available to Purchase
Romualdo Barroso-Sousa, Tanya E. Keenan, Sonia Pernas, Pedro Exman, Esha Jain, Ana C. Garrido-Castro, Melissa Hughes, Brittany Bychkovsky, Renato Umeton, Janet L. Files, Neal I. Lindeman, Laura E. MacConaill, F. Stephen Hodi, Ian E. Krop, Deborah Dillon, Eric P. Winer, Nikhil Wagle, Nancy U. Lin, Elizabeth A. Mittendorf, Eliezer M. Van Allen, Sara M. Tolaney
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11): 2565–2572.
https://doi.org/10.1158/1078-0432.CCR-19-3507
Published: 01 June 2020
View article titled, Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

Abstract B26: Accelerating prediction of tumor vulnerabilities using next-generation cancer models

Free
Yuen-Yi Tseng, Paula Keskula, Andrew L. Hong, Shubhroz Gill, Jaime H. Cheah, Gregory V. Kryukov, Aviad Tsherniak, Francisca Vazquez, Glenn Cowley, Coyin Oh, Anson Peng, Abeer Sayeed, Rebecca Deasy, Peter Ronning, Philip Kantoff, Levi Garraway, Mark A. Rubin, Calvin Kuo, Sidharth Puram, Adi Gazdar, Filemon S. Dela Cruz, Jr., Adam Bass, Jr., Nikhil Wagle, Keith L. Ligon, Katherine Janeway, David Root, Stuart L. Schreiber, Paul A. Clemons, Aly Shamji, William C. Hahn, Todd R. Golub, Jesse S. Boehm
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): B26.
https://doi.org/10.1158/1557-3265.PDX16-B26
Published: 15 August 2016
View article titled, Abstract B26: Accelerating prediction of tumor vulnerabilities using next-generation cancer models
Journal Articles

Abstract PR02: Identification of ERK1/2 mutations that confer resistance to MAPK pathway inhibitors

Free
Eva M. Goetz, Mahmoud Ghandi, Daniel Treacy, Nikhil Wagle, Levi A. Garraway
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (4_Supplement): PR02.
https://doi.org/10.1158/1557-3265.PMS14-PR02
Published: 13 February 2015
View article titled, Abstract PR02: Identification of ERK1/2 mutations that confer resistance to MAPK pathway inhibitors
Journal Articles

Abstract B20: A genome-scale RNA interference screen for resistance mechanisms to BRAF inhibition in melanoma

Free
Steven Whittaker, Eran Hodis, Nikhil Wagle, Jessica Hsiao, Glenn Cowley, David Root, Levi Garraway
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (10_Supplement): B20.
https://doi.org/10.1158/1078-0432.MECHRES-B20
Published: 04 March 2013
View article titled, Abstract B20: A genome-scale RNA interference screen for resistance mechanisms to BRAF inhibition in melanoma
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