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Nian Wu
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Journal Articles

A Phase Ib/II Randomized Study of RO4929097, a Gamma-Secretase or Notch Inhibitor with or without Vismodegib, a Hedgehog Inhibitor, in Advanced Sarcoma

Mrinal M. Gounder, Evan Rosenbaum, Nian Wu, Mark A. Dickson, Tahir N. Sheikh, Sandra P. D'Angelo, Ping Chi, Mary Lou Keohan, Joseph P. Erinjeri, Cristina R. Antonescu, Narasimhan Agaram, Meera R. Hameed, Moriah Martindale, Robert A. Lefkowitz, Aimee M. Crago, Sam Singer, William D. Tap, Naoko Takebe, Li-Xuan Qin, Gary K. Schwartz
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (8): 1586–1594.
https://doi.org/10.1158/1078-0432.CCR-21-3874
Published: 14 April 2022
View article titled, A Phase Ib/II Randomized Study of RO4929097, a Gamma-Secretase or Notch Inhibitor with or without Vismodegib, a Hedgehog Inhibitor, in Advanced Sarcoma
Open the PDF for A Phase Ib/II Randomized Study of RO4929097, a Gamma-Secretase or Notch Inhibitor with or without Vismodegib, a Hedgehog Inhibitor, in Advanced Sarcoma in another window
Includes: Supplementary data
Journal Articles

Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial

Ran Xu, Fumiko Shimizu, Koos Hovinga, Kathryn Beal, Sasan Karimi, Leif Droms, Kyung K. Peck, Philip Gutin, J. Bryan Iorgulescu, Thomas Kaley, Lisa DeAngelis, Elena Pentsova, Craig Nolan, Christian Grommes, Timothy Chan, Dylan Bobrow, Adilia Hormigo, Justin R. Cross, Nian Wu, Naoko Takebe, Katherine Panageas, Percy Ivy, Jeffrey G. Supko, Viviane Tabar, Antonio Omuro
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (19): 4786–4796.
https://doi.org/10.1158/1078-0432.CCR-16-0048
Published: 02 October 2016
View article titled, Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial
Open the PDF for Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial in another window
Includes: Supplementary data
Journal Articles

Phase I Study of Flavopiridol with Oxaliplatin and Fluorouracil/Leucovorin in Advanced Solid Tumors

Dana Rathkopf, Mark A. Dickson, Darren R. Feldman, Richard D. Carvajal, Manish A. Shah, Nian Wu, Robert Lefkowitz, Mithat Gonen, Lauren M. Cane, Heather J. Dials, Jennifer L. Winkelmann, George J. Bosl, Gary K. Schwartz
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (23): 7405–7411.
https://doi.org/10.1158/1078-0432.CCR-09-1502
Published: 30 November 2009
View article titled, Phase I Study of Flavopiridol with Oxaliplatin and Fluorouracil/Leucovorin in Advanced Solid Tumors
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Journal Articles

A Phase 1 Dose-Escalation Study of Irinotecan in Combination with 17-Allylamino-17-Demethoxygeldanamycin in Patients with Solid Tumors

Archie N. Tse, David S. Klimstra, Mithat Gonen, Manish Shah, Tahir Sheikh, Rachel Sikorski, Richard Carvajal, Janet Mui, Caroll Tipian, Eileen O'Reilly, Ki Chung, Robert Maki, Robert Lefkowitz, Karen Brown, Katia Manova-Todorova, Nian Wu, Merrill J. Egorin, David Kelsen, Gary K. Schwartz
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (20): 6704–6711.
https://doi.org/10.1158/1078-0432.CCR-08-1006
Published: 16 October 2008
View article titled, A Phase 1 Dose-Escalation Study of Irinotecan in Combination with 17-Allylamino-17-Demethoxygeldanamycin in Patients with Solid Tumors
Open the PDF for A Phase 1 Dose-Escalation Study of Irinotecan in Combination with 17-Allylamino-17-Demethoxygeldanamycin in Patients with Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Tolerability, Pharmacodynamics, and Pharmacokinetics Studies of Depsipeptide (Romidepsin) in Patients with Acute Myelogenous Leukemia or Advanced Myelodysplastic Syndromes

Virginia M. Klimek, Sophia Fircanis, Peter Maslak, Ilhem Guernah, Michael Baum, Nian Wu, Katherine Panageas, John J. Wright, Pier Paolo Pandolfi, Stephen D. Nimer
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (3): 826–832.
https://doi.org/10.1158/1078-0432.CCR-07-0318
Published: 01 February 2008
View article titled, Tolerability, Pharmacodynamics, and Pharmacokinetics Studies of Depsipeptide (Romidepsin) in Patients with Acute Myelogenous Leukemia or Advanced Myelodysplastic Syndromes
Open the PDF for Tolerability, Pharmacodynamics, and Pharmacokinetics Studies of Depsipeptide (Romidepsin) in Patients with Acute Myelogenous Leukemia or Advanced Myelodysplastic Syndromes in another window