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Neeraj Agarwal
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Journal Articles

Targeting the FGFR Pathway in Patients with Advanced Solid Tumors

Chadi Hage Chehade, Zeynep Irem Ozay, Neeraj Agarwal
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (20): 4549–4551.
https://doi.org/10.1158/1078-0432.CCR-24-1711
Published: 15 October 2024
View article titled, Targeting the FGFR Pathway in Patients with Advanced Solid Tumors
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Journal Articles

Abiraterone, Olaparib, or Abiraterone + Olaparib in First-Line Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects (BRCAAway)

Maha Hussain, Masha Kocherginsky, Neeraj Agarwal, Nabil Adra, Jingsong Zhang, Channing J. Paller, Joel Picus, Zachery R. Reichert, Russell Z. Szmulewitz, Scott T. Tagawa, Timothy M. Kuzel, Latifa A. Bazzi, Stephanie Daignault-Newton, Young E. Whang, Robert Dreicer, Ryan D. Stephenson, Matthew B. Rettig, Daniel Shevrin, Travis Gerke, Arul M. Chinnaiyan, Emmanuel S. Antonarakis
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (19): 4318–4328.
https://doi.org/10.1158/1078-0432.CCR-24-1402
Published: 01 October 2024
View article titled, Abiraterone, Olaparib, or Abiraterone + Olaparib in First-Line Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects (BRCAAway)
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Includes: Supplementary data
Journal Articles

A Signal-Finding Study of Abemaciclib in Heavily Pretreated Patients with Metastatic Castration–Resistant Prostate Cancer: Results from CYCLONE 1

Neeraj Agarwal, Daniel Castellano, Teresa Alonso-Gordoa, Jose Angel Arranz Arija, Emeline Colomba, Gwenaelle Gravis, Loic Mourey, Stephane Oudard, Aude Fléchon, Macarena González, Pablo M. Rey, Michael T. Schweizer, Enrique Gallardo, Erica Johnston, Arjun Balar, Nadine Haddad, Adams K. Appiah, Karim Nacerddine, José M. Piulats
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (11): 2377–2383.
https://doi.org/10.1158/1078-0432.CCR-23-3436
Published: 03 June 2024
View article titled, A Signal-Finding Study of Abemaciclib in Heavily Pretreated Patients with Metastatic Castration–Resistant Prostate Cancer: Results from CYCLONE 1
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Includes: Supplementary data
Journal Articles

Phase I Study of ORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer Progressing on Enzalutamide

Wassim Abida, Andrew W. Hahn, Neal Shore, Neeraj Agarwal, Paul Sieber, Matthew R. Smith, Tanya Dorff, Paul Monk, Matthew Rettig, Rupal Patel, Anne Page, Maureen Duff, Rongda Xu, Jian Wang, Shravani Barkund, Aleksandr Pankov, Amber Wang, Melissa R. Junttila, Pratik S. Multani, Anneleen Daemen, Edna Chow Maneval, Christopher J. Logothetis, Michael J. Morris
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (6): 1111–1120.
https://doi.org/10.1158/1078-0432.CCR-23-3508
Published: 15 March 2024
View article titled, Phase I Study of ORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer Progressing on Enzalutamide
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Includes: Supplementary data
Journal Articles

Unique Spectrum of Activating BRAF Alterations in Prostate Cancer

Alex Chehrazi-Raffle, Hanna Tukachinsky, Eamon Toye, Smruthy Sivakumar, Alexa B. Schrock, Hannah E. Bergom, Hedyeh Ebrahimi, Sumanta Pal, Tanya Dorff, Neeraj Agarwal, Brandon A. Mahal, Geoffrey R. Oxnard, Justin Hwang, Emmanuel S. Antonarakis
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (19): 3948–3957.
https://doi.org/10.1158/1078-0432.CCR-23-1393
Published: 02 October 2023
View article titled, Unique Spectrum of Activating <em>BRAF</em> Alterations in Prostate Cancer
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Includes: Supplementary data
Journal Articles

Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2, or ATM Alterations Identified by Testing Circulating Tumor DNA

Nobuaki Matsubara, Johann de Bono, David Olmos, Giuseppe Procopio, Satoru Kawakami, Yüksel Ürün, Robbert van Alphen, Aude Flechon, Michael A. Carducci, Young Deuk Choi, Sebastien J. Hotte, Ernesto Korbenfeld, Gero Kramer, Neeraj Agarwal, Kim N. Chi, Simon Dearden, Christopher Gresty, Jinyu Kang, Christian Poehlein, Elizabeth A. Harrington, Maha Hussain
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (1): 92–99.
https://doi.org/10.1158/1078-0432.CCR-21-3577
Published: 04 January 2023
View article titled, Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and <em>BRCA1, BRCA2</em>, or <em>ATM</em> Alterations Identified by Testing Circulating Tumor DNA
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Includes: Supplementary data
Journal Articles

Detection of BRCA1, BRCA2, and ATM Alterations in Matched Tumor Tissue and Circulating Tumor DNA in Patients with Prostate Cancer Screened in PROfound

Kim N. Chi, Alan Barnicle, Caroline Sibilla, Zhongwu Lai, Claire Corcoran, J. Carl Barrett, Carrie A. Adelman, Ping Qiu, Ashley Easter, Simon Dearden, Geoffrey R. Oxnard, Neeraj Agarwal, Arun Azad, Johann de Bono, Joaquin Mateo, David Olmos, Antoine Thiery-Vuillemin, Elizabeth A. Harrington
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (1): 81–91.
https://doi.org/10.1158/1078-0432.CCR-22-0931
Published: 04 January 2023
View article titled, Detection of <em>BRCA1</em>, <em>BRCA2</em>, and <em>ATM</em> Alterations in Matched Tumor Tissue and Circulating Tumor DNA in Patients with Prostate Cancer Screened in PROfound
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Includes: Supplementary data
Journal Articles

SPOP Mutations as a Predictive Biomarker for Androgen Receptor Axis–Targeted Therapy in De Novo Metastatic Castration-Sensitive Prostate Cancer

Umang Swami, Ryon P. Graf, Roberto H. Nussenzveig, Virginia Fisher, Hanna Tukachinsky, Alexa B. Schrock, Gerald Li, Jeffrey S. Ross, Nicolas Sayegh, Nishita Tripathi, Vinay Mathew Thomas, Geoffrey R. Oxnard, Emmanuel S. Antonarakis, Neeraj Agarwal
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (22): 4917–4925.
https://doi.org/10.1158/1078-0432.CCR-22-2228
Published: 14 November 2022
View article titled, SPOP Mutations as a Predictive Biomarker for Androgen Receptor Axis–Targeted Therapy in <em>De Novo</em> Metastatic Castration-Sensitive Prostate Cancer
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Includes: Supplementary data
Journal Articles

An Evolving Role for AXL in Metastatic Renal Cell Carcinoma

Andrew W. Hahn, Daniel J. George, Neeraj Agarwal
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (24): 6619–6621.
https://doi.org/10.1158/1078-0432.CCR-21-3029
Published: 15 December 2021
View article titled, An Evolving Role for AXL in Metastatic Renal Cell Carcinoma
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Journal Articles

Complementary Role of Circulating Tumor DNA Assessment and Tissue Genomic Profiling in Metastatic Renal Cell Carcinoma

Zeynep B. Zengin, Caroline Weipert, Nicholas J. Salgia, Nazli Dizman, Joann Hsu, Luis Meza, Alexander Chehrazi-Raffle, Ramya Muddasani, Sabrina Salgia, Jasnoor Malhotra, Neal Chawla, Errol J. Philip, Lesli Kiedrowski, Benjamin L. Maughan, Nityam Rathi, Divyam Goel, Toni K. Choueiri, Neeraj Agarwal, Sumanta K. Pal
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (17): 4807–4813.
https://doi.org/10.1158/1078-0432.CCR-21-0572
Published: 01 September 2021
View article titled, Complementary Role of Circulating Tumor DNA Assessment and Tissue Genomic Profiling in Metastatic Renal Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Correction: Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer

Sophie J. Cowman, Daniel G. Fuja, Xian-De Liu, Rebecca S. Slack Tidwell, Neelima Kandula, Deepika Sirohi, Archana M. Agarwal, Lyska L. Emerson, Sheryl R. Tripp, Jeffrey S. Mohlman, Miekan Stonhill, Guillermina Garcia, Christopher J. Conley, Adam A. Olalde, Timothy Sargis, Adela Ramirez-Torres, Jose A. Karam, Christopher G. Wood, Kanishka Sircar, Pheroze Tamboli, Kenneth Boucher, Benjamin Maughan, Benjamin T. Spike, Thai H. Ho, Neeraj Agarwal, Eric Jonasch, Mei Yee Koh
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (11): 3265.
https://doi.org/10.1158/1078-0432.CCR-21-1235
Published: 01 June 2021
View article titled, Correction: Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer
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Journal Articles

A Randomized Phase II Study of Androgen Deprivation Therapy with or without Palbociclib in RB-positive Metastatic Hormone-Sensitive Prostate Cancer

Phillip L. Palmbos, Stephanie Daignault-Newton, Scott A. Tomlins, Neeraj Agarwal, Przemyslaw Twardowski, Alicia K. Morgans, Wm. Kevin Kelly, Vivek K. Arora, Emmanuel S. Antonarakis, Javed Siddiqui, Jon A. Jacobson, Matthew S. Davenport, Dan R. Robinson, Arul M. Chinnaiyan, Karen E. Knudsen, Maha Hussain
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (11): 3017–3027.
https://doi.org/10.1158/1078-0432.CCR-21-0024
Published: 01 June 2021
View article titled, A Randomized Phase II Study of Androgen Deprivation Therapy with or without Palbociclib in RB-positive Metastatic Hormone-Sensitive Prostate Cancer
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Journal Articles

Baseline Circulating Tumor Cell Count as a Prognostic Marker of PSA Response and Disease Progression in Metastatic Castrate-Sensitive Prostate Cancer (SWOG S1216)

Amir Goldkorn, Catherine Tangen, Melissa Plets, Gareth J. Morrison, Alexander Cunha, Tong Xu, Jacek K. Pinski, Sue A. Ingles, Timothy Triche, Andrea L. Harzstark, Manish Kohli, Gary R. MacVicar, Daniel A. Vaena, Anthony W. Crispino, David J. McConkey, Primo N. Lara, Jr, Maha H.A. Hussain, David I. Quinn, Nicholas J. Vogelzang, Ian Murchie Thompson, Jr, Neeraj Agarwal
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (7): 1967–1973.
https://doi.org/10.1158/1078-0432.CCR-20-3587
Published: 01 April 2021
View article titled, Baseline Circulating Tumor Cell Count as a Prognostic Marker of PSA Response and Disease Progression in Metastatic Castrate-Sensitive Prostate Cancer (SWOG S1216)
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Journal Articles

Checking the Hippo in Sarcomatoid Renal Cell Carcinoma with Immunotherapy

Joyce K. Hwang, Neeraj Agarwal, James Brugarolas, Tian Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (1): 5–7.
https://doi.org/10.1158/1078-0432.CCR-20-3506
Published: 04 January 2021
View article titled, Checking the Hippo in Sarcomatoid Renal Cell Carcinoma with Immunotherapy
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Journal Articles

Quest for Ideal Composite Biomarkers for Response to Immunotherapies

Umang Swami, Roberto H. Nussenzveig, Neeraj Agarwal
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (19): 5059–5061.
https://doi.org/10.1158/1078-0432.CCR-20-2321
Published: 01 October 2020
View article titled, Quest for Ideal Composite Biomarkers for Response to Immunotherapies
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Journal Articles

Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer

Sophie J. Cowman, Daniel G. Fuja, Xian-De Liu, Rebecca S. Slack Tidwell, Neelima Kandula, Deepika Sirohi, Archana M. Agarwal, Lyska L. Emerson, Sheryl R. Tripp, Jeffrey S. Mohlman, Miekan Stonhill, Guillermina Garcia, Christopher J. Conley, Adam A. Olalde, Timothy Sargis, Adela Ramirez-Torres, Jose A. Karam, Christopher G. Wood, Kanishka Sircar, Pheroze Tamboli, Kenneth Boucher, Benjamin Maughan, Benjamin T. Spike, Thai H. Ho, Neeraj Agarwal, Eric Jonasch, Mei Yee Koh
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (18): 4970–4982.
https://doi.org/10.1158/1078-0432.CCR-19-3890
Published: 15 September 2020
View article titled, Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer
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Includes: Supplementary data
Journal Articles

Abstract IA10: Developing rational combination therapy with checkpoint inhibitors

Megan M. Tu, Francis Y. F. Lee, Robert T. Jones, Abigail K. Kimball, Elizabeth Saravia, Robert F. Graziano, Brianne Coleman, Krista Menard, Jun Yan, Erin Michaud, Han Chang, Hany A. Abdel-Hafiz, Andrii I. Rozhok, Jason E. Duex, Neeraj Agarwal, Ana Chauca-Diaz, Linda K. Johnson, Terry L. Ng, John C. Cambier, Eric T. Clambey, James C. Costello, Alan J. Korman, Dan Theodorescu
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (15_Supplement): IA10.
https://doi.org/10.1158/1557-3265.BLADDER19-IA10
Published: 03 August 2020
View article titled, Abstract IA10: Developing rational combination therapy with checkpoint inhibitors
Journal Articles

Routine Plasma-Based Genotyping to Comprehensively Detect Germline, Somatic, and Reversion BRCA Mutations among Patients with Advanced Solid Tumors

Neelima Vidula, Thereasa A. Rich, Oliver Sartor, Jennifer Yen, Aaron Hardin, Tracy Nance, Michael B. Lilly, Mohammad Amin Nezami, Sandip P. Patel, Benedito A. Carneiro, Alice C. Fan, Adam M. Brufsky, Barbara A. Parker, Benjamin B. Bridges, Neeraj Agarwal, Benjamin L. Maughan, Victoria M. Raymond, Stephen R. Fairclough, Richard B. Lanman, Aditya Bardia, Massimo Cristofanilli
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11): 2546–2555.
https://doi.org/10.1158/1078-0432.CCR-19-2933
Published: 01 June 2020
View article titled, Routine Plasma-Based Genotyping to Comprehensively Detect Germline, Somatic, and Reversion <em>BRCA</em> Mutations among Patients with Advanced Solid Tumors
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Includes: Supplementary data
Journal Articles

Prospective Evaluation of Bone Metabolic Markers as Surrogate Markers of Response to Radium-223 Therapy in Metastatic Castration-resistant Prostate Cancer

Neeraj Agarwal, Roberto Nussenzveig, Andrew W. Hahn, John M. Hoffman, Kathryn Morton, Sumati Gupta, Julia Batten, Jared Thorley, Josiah Hawks, Victor Sacristan Santos, Gayatri Nachaegari, Xuechen Wang, Kenneth Boucher, Benjamin Haaland, Benjamin L. Maughan
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (9): 2104–2110.
https://doi.org/10.1158/1078-0432.CCR-19-2591
Published: 01 May 2020
View article titled, Prospective Evaluation of Bone Metabolic Markers as Surrogate Markers of Response to Radium-223 Therapy in Metastatic Castration-resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Sarcomatoid Renal Cell Carcinoma: The Apple Doesn't Fall Far from the Tree

Paulo Bergerot, Neeraj Agarwal, Sumanta K. Pal, Jeremy Jones
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (21): 6381–6383.
https://doi.org/10.1158/1078-0432.CCR-17-2039
Published: 31 October 2017
View article titled, Sarcomatoid Renal Cell Carcinoma: The Apple Doesn't Fall Far from the Tree
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