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Journal Articles

Rb Tumor Suppressor in Small Cell Lung Cancer: Combined Genomic and IHC Analysis with a Description of a Distinct Rb-Proficient Subset

Christopher A. Febres-Aldana, Jason C. Chang, Ryan Ptashkin, Yuhan Wang, Erika Gedvilaite, Marina K. Baine, William D. Travis, Katia Ventura, Francis Bodd, Helena A. Yu, Alvaro Quintanal-Villalonga, W. Victoria Lai, Jacklynn V. Egger, Michael Offin, Marc Ladanyi, Charles M. Rudin, Natasha Rekhtman

Clin Cancer Res OF1–OF12.

DOI: https://doi.org/10.1158/1078-0432.CCR-22-1115

Published: 19 July 2022

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Includes: Supplementary data

Journal Articles

Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

Clin Cancer Res (2021) 27 (14): 4066–4076.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-0423

Published: 15 July 2021

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Includes: Supplementary data

Journal Articles

A Performance Comparison of Commonly Used Assays to Detect RET Fusions

Soo-Ryum Yang, Umut Aypar, Ezra Y. Rosen, Douglas A. Mata, Ryma Benayed, Kerry Mullaney, Gowtham Jayakumaran, Yanming Zhang, Denise Frosina, Alexander Drilon, Marc Ladanyi, Achim A. Jungbluth, Natasha Rekhtman, Jaclyn F. Hechtman

Clin Cancer Res (2021) 27 (5): 1316–1328.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-3208

Published: 01 March 2021

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Journal Articles

MET Exon 14–altered Lung Cancers and MET Inhibitor Resistance

Clin Cancer Res (2021) 27 (3): 799–806.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-2861

Published: 01 February 2021

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Includes: Supplementary data

Journal Articles

The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer

Clin Cancer Res (2020) 26 (21): 5701–5708.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-1825

Published: 02 November 2020

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Journal Articles

Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in EGFR-Mutant Lung Cancer

Adam J. Schoenfeld, Joseph M. Chan, Daisuke Kubota, Hiroki Sato, Hira Rizvi, Yahya Daneshbod, Jason C. Chang, Paul K. Paik, Michael Offin, Maria E. Arcila, Monika A. Davare, Ujwal Shinde, Dana Pe'er, Natasha Rekhtman, Mark G. Kris, Romel Somwar, Gregory J. Riely, Marc Ladanyi, Helena A. Yu

Clin Cancer Res (2020) 26 (11): 2654–2663.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-3563

Published: 01 June 2020

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Includes: Supplementary data

Journal Articles

Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma

Clin Cancer Res (2019) 25 (24): 7475–7484.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-1651

Published: 13 December 2019

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Journal Articles

Comprehensive Next-Generation Sequencing Unambiguously Distinguishes Separate Primary Lung Carcinomas From Intrapulmonary Metastases: Comparison with Standard Histopathologic Approach

Jason C. Chang, Deepu Alex, Matthew Bott, Kay See Tan, Venkatraman Seshan, Andrew Golden, Jennifer L. Sauter, Darren J. Buonocore, Chad M. Vanderbilt, Sounak Gupta, Patrice Desmeules, Francis M. Bodd, Gregory J. Riely, Valerie W. Rusch, David R. Jones, Maria E. Arcila, William D. Travis, Marc Ladanyi, Natasha Rekhtman

Clin Cancer Res (2019) 25 (23): 7113–7125.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-1700

Published: 02 December 2019

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Includes: Supplementary data

Journal Articles

PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer

Benjamin H. Lok, Eric E. Gardner, Valentina E. Schneeberger, Andy Ni, Patrice Desmeules, Natasha Rekhtman, Elisa de Stanchina, Beverly A. Teicher, Nadeem Riaz, Simon N. Powell, John T. Poirier, Charles M. Rudin

Clin Cancer Res (2017) 23 (2): 523–535.

DOI: https://doi.org/10.1158/1078-0432.CCR-16-1040

Published: 15 January 2017

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Includes: Supplementary data

Journal Articles

An Expression Signature as an Aid to the Histologic Classification of Non–Small Cell Lung Cancer

Luc Girard, Jaime Rodriguez-Canales, Carmen Behrens, Debrah M. Thompson, Ihab W. Botros, Hao Tang, Yang Xie, Natasha Rekhtman, William D. Travis, Ignacio I. Wistuba, John D. Minna, Adi F. Gazdar

Clin Cancer Res (2016) 22 (19): 4880–4889.

DOI: https://doi.org/10.1158/1078-0432.CCR-15-2900

Published: 02 October 2016

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Journal Articles

Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma–like and Non–Small Cell Carcinoma–like Subsets

Clin Cancer Res (2016) 22 (14): 3618–3629.

DOI: https://doi.org/10.1158/1078-0432.CCR-15-2946

Published: 14 July 2016

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Includes: Supplementary data

Journal Articles

Analysis of Tumor Specimens at the Time of Acquired Resistance to EGFR-TKI Therapy in 155 Patients with EGFR-Mutant Lung Cancers

Helena A. Yu, Maria E. Arcila, Natasha Rekhtman, Camelia S. Sima, Maureen F. Zakowski, William Pao, Mark G. Kris, Vincent A. Miller, Marc Ladanyi, Gregory J. Riely

Clin Cancer Res (2013) 19 (8): 2240–2247.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-2246

Published: 15 April 2013

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Journal Articles

Clarifying the Spectrum of Driver Oncogene Mutations in Biomarker-Verified Squamous Carcinoma of Lung: Lack of EGFR/KRAS and Presence of PIK3CA/AKT1 Mutations

Natasha Rekhtman, Paul K. Paik, Maria E. Arcila, Laura J. Tafe, Geoffrey R. Oxnard, Andre L. Moreira, William D. Travis, Maureen F. Zakowski, Mark G. Kris, Marc Ladanyi

Clin Cancer Res (2012) 18 (4): 1167–1176.

DOI: https://doi.org/10.1158/1078-0432.CCR-11-2109

Published: 14 February 2012

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Includes: Supplementary data

NARROW

Rb Tumor Suppressor in Small Cell Lung Cancer: Combined Genomic and IHC Analysis with a Description of a Distinct Rb-Proficient Subset

Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

A Performance Comparison of Commonly Used Assays to Detect RET Fusions

MET Exon 14–altered Lung Cancers and MET Inhibitor Resistance

The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer

Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in EGFR-Mutant Lung Cancer

Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma

Comprehensive Next-Generation Sequencing Unambiguously Distinguishes Separate Primary Lung Carcinomas From Intrapulmonary Metastases: Comparison with Standard Histopathologic Approach

PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer

An Expression Signature as an Aid to the Histologic Classification of Non–Small Cell Lung Cancer

Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma–like and Non–Small Cell Carcinoma–like Subsets

Analysis of Tumor Specimens at the Time of Acquired Resistance to EGFR-TKI Therapy in 155 Patients with EGFR-Mutant Lung Cancers

Clarifying the Spectrum of Driver Oncogene Mutations in Biomarker-Verified Squamous Carcinoma of Lung: Lack of EGFR/KRAS and Presence of PIK3CA/AKT1 Mutations

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