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Natalia Issaeva
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Journal Articles

Abstract PO-018: Pathological analysis of newly established immunocompetent mice with full HPV16 genome integration

Xue Li, Aditi Kothari, Hina Rehmani, Wendell G. Yarbrough, Natalia Issaeva
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (18_Supplement): PO-018.
https://doi.org/10.1158/1557-3265.AACRAHNS23-PO-018
Published: 15 September 2023
View article titled, Abstract PO-018: Pathological analysis of newly established immunocompetent mice with full HPV16 genome integration
Journal Articles

Abstract PO-092: Molecular characterization of the salivary adenoid cystic carcinoma tumor immune landscape by anatomic subsite

Jason Tasoulas, Travis Schrank, Steven Johnson, Kimon Divaris, Stamatios Theocharis, Trevor Hackman, Siddharth Sheth, Kedar Kirtane, Juan Hernandez-Prera, Christine Chung, Wendell Gray Yarbrough, Natalia Issaeva, Antonio Amelio
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (18_Supplement): PO-092.
https://doi.org/10.1158/1557-3265.AACRAHNS23-PO-092
Published: 15 September 2023
View article titled, Abstract PO-092: Molecular characterization of the salivary adenoid cystic carcinoma tumor immune landscape by anatomic subsite
Journal Articles

Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma

Lin Xiao, Klaartje Somers, Jayne Murray, Ruby Pandher, Mawar Karsa, Emma Ronca, Angelika Bongers, Rachael Terry, Anahid Ehteda, Laura D. Gamble, Natalia Issaeva, Katerina I. Leonova, Aisling O'Connor, Chelsea Mayoh, Pooja Venkat, Hazel Quek, Jennifer Brand, Frances K. Kusuma, Jessica A. Pettitt, Erin Mosmann, Adam Kearns, Georgina Eden, Stephanie Alfred, Sophie Allan, Lei Zhai, Alvin Kamili, Andrew J. Gifford, Daniel R. Carter, Michelle J. Henderson, Jamie I. Fletcher, Glenn Marshall, Ricky W. Johnstone, Anthony J. Cesare, David S. Ziegler, Andrei V. Gudkov, Katerina V. Gurova, Murray D. Norris, Michelle Haber
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (15): 4338–4352.
https://doi.org/10.1158/1078-0432.CCR-20-2357
Published: 01 August 2021
View article titled, Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma
Open the PDF for Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma in another window
Includes: Multimedia, Supplementary data
Journal Articles

Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck

Jong Woo Lee, Janaki Parameswaran, Teresa Sandoval-Schaefer, Kyung Jin Eoh, Dong-hua Yang, Fang Zhu, Ranee Mehra, Roshan Sharma, Stephen G. Gaffney, Elizabeth B. Perry, Jeffrey P. Townsend, Ilya G. Serebriiskii, Erica A. Golemis, Natalia Issaeva, Wendell G. Yarbrough, Ja Seok Koo, Barbara Burtness
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (11): 3430–3442.
https://doi.org/10.1158/1078-0432.CCR-18-0440
Published: 03 June 2019
View article titled, Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck
Open the PDF for Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck in another window
Includes: Supplementary data
Journal Articles

Abstract 68: Functional interactions of HPV and PARP-1 in head and neck cancer

Cyril S. Gary, Michael Hajek, Asel Biktasova, Andrew Sewell, Yarbrough G. Wendell, Natalia Issaeva
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (23_Supplement): 68.
https://doi.org/10.1158/1557-3265.AACRAHNS17-68
Published: 30 November 2017
View article titled, Abstract 68: Functional interactions of HPV and PARP-1 in head and neck cancer
Journal Articles

Demethylation Therapy as a Targeted Treatment for Human Papillomavirus–Associated Head and Neck Cancer

Asel Biktasova, Michael Hajek, Andrew Sewell, Cyril Gary, Gary Bellinger, Hari A. Deshpande, Aarti Bhatia, Barbara Burtness, Benjamin Judson, Saral Mehra, Wendell G. Yarbrough, Natalia Issaeva
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (23): 7276–7287.
https://doi.org/10.1158/1078-0432.CCR-17-1438
Published: 30 November 2017
View article titled, Demethylation Therapy as a Targeted Treatment for Human Papillomavirus–Associated Head and Neck Cancer
Open the PDF for Demethylation Therapy as a Targeted Treatment for Human Papillomavirus–Associated Head and Neck Cancer in another window
Includes: Supplementary data
Journal Articles

Reverse-Phase Protein Array Profiling of Oropharyngeal Cancer and Significance of PIK3CA Mutations in HPV-Associated Head and Neck Cancer

Andrew Sewell, Brandee Brown, Asel Biktasova, Gordon B. Mills, Yiling Lu, Darren R. Tyson, Natalia Issaeva, Wendell G. Yarbrough
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2014) 20 (9): 2300–2311.
https://doi.org/10.1158/1078-0432.CCR-13-2585
Published: 30 April 2014
View article titled, Reverse-Phase Protein Array Profiling of Oropharyngeal Cancer and Significance of PIK3CA Mutations in HPV-Associated Head and Neck Cancer
Open the PDF for Reverse-Phase Protein Array Profiling of Oropharyngeal Cancer and Significance of PIK3CA Mutations in HPV-Associated Head and Neck Cancer in another window
Includes: Supplementary data
Journal Articles

Downregulation of SMG-1 in HPV-Positive Head and Neck Squamous Cell Carcinoma Due to Promoter Hypermethylation Correlates with Improved Survival

Evgenia Gubanova, Brandee Brown, Sergei V. Ivanov, Thomas Helleday, Gordon B. Mills, Wendell G. Yarbrough, Natalia Issaeva
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (5): 1257–1267.
https://doi.org/10.1158/1078-0432.CCR-11-2058
Published: 01 March 2012
View article titled, Downregulation of SMG-1 in HPV-Positive Head and Neck Squamous Cell Carcinoma Due to Promoter Hypermethylation Correlates with Improved Survival
Open the PDF for Downregulation of SMG-1 in HPV-Positive Head and Neck Squamous Cell Carcinoma Due to Promoter Hypermethylation Correlates with Improved Survival in another window
Includes: Supplementary data