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Nancy Ratner
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Journal Articles

Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis

Teresa González-Muñoz, Angela Di Giannatale, Susana García-Silva, Vanesa Santos, Sara Sánchez-Redondo, Claudia Savini, Osvaldo Graña-Castro, Carmen Blanco-Aparicio, Suzanne Fischer, Olivier De Wever, Edgar Creus-Bachiller, Sara Ortega-Bertran, David J. Pisapia, Jose L. Rodríguez-Peralto, Juana Fernández-Rodríguez, Cleofé Romagosa Pérez-Portabella, Rita Alaggio, Maria Serena Benassi, Laura Pazzaglia, Katia Scotlandi, Nancy Ratner, Kaleb Yohay, Charles P. Theuer, Héctor Peinado
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (18): 3744–3758.
https://doi.org/10.1158/1078-0432.CCR-22-2462
Published: 15 September 2023
View article titled, Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
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Includes: Supplementary data
Journal Articles

The Need for New Treatments Targeting MPNST: The Potential of Strategies Combining MEK Inhibitors with Antiangiogenic Agents

Teresa González-Muñoz, AeRang Kim, Nancy Ratner, Héctor Peinado
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (15): 3185–3195.
https://doi.org/10.1158/1078-0432.CCR-21-3760
Published: 02 August 2022
View article titled, The Need for New Treatments Targeting MPNST: The Potential of Strategies Combining MEK Inhibitors with Antiangiogenic Agents
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Journal Articles

Targeted Inhibition of the Dual Specificity Phosphatases DUSP1 and DUSP6 Suppress MPNST Growth via JNK

Annmarie Ramkissoon, Katherine E. Chaney, David Milewski, Kyle B. Williams, Rory L. Williams, Kwangmin Choi, Adam Miller, Tanya V. Kalin, Joseph G. Pressey, Sara Szabo, Mohammad Azam, David A. Largaespada, Nancy Ratner
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (13): 4117–4127.
https://doi.org/10.1158/1078-0432.CCR-18-3224
Published: 01 July 2019
View article titled, Targeted Inhibition of the Dual Specificity Phosphatases DUSP1 and DUSP6 Suppress MPNST Growth via JNK
Open the PDF for Targeted Inhibition of the Dual Specificity Phosphatases DUSP1 and DUSP6 Suppress MPNST Growth via JNK in another window
Includes: Supplementary data
Journal Articles

Editor's Note: Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment

Jilong Yang, Antti Ylipää, Yan Sun, Hong Zheng, Kexin Chen, Matti Nykter, Jonathan Trent, Nancy Ratner, Dina C. Lev, Wei Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (10): 3195.
https://doi.org/10.1158/1078-0432.CCR-19-1144
Published: 15 May 2019
View article titled, Editor's Note: Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment
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Journal Articles

Abstract IA15: Using gene expression analyses to identify MPNST therapeutics

Nancy Ratner
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (2_Supplement): IA15.
https://doi.org/10.1158/1557-3265.SARCOMAS17-IA15
Published: 15 January 2018
View article titled, Abstract IA15: Using gene expression analyses to identify MPNST therapeutics
Journal Articles

Ras-Driven Transcriptome Analysis Identifies Aurora Kinase A as a Potential Malignant Peripheral Nerve Sheath Tumor Therapeutic Target

Ami V. Patel, David Eaves, Walter J. Jessen, Tilat A. Rizvi, Jeffrey A. Ecsedy, Mark G. Qian, Bruce J. Aronow, John P. Perentesis, Eduard Serra, Timothy P. Cripe, Shyra J. Miller, Nancy Ratner
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (18): 5020–5030.
https://doi.org/10.1158/1078-0432.CCR-12-1072
Published: 16 September 2012
View article titled, Ras-Driven Transcriptome Analysis Identifies Aurora Kinase A as a Potential Malignant Peripheral Nerve Sheath Tumor Therapeutic Target
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Includes: Supplementary data
Journal Articles

Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment

Jilong Yang, Antti Ylipää, Yan Sun, Hong Zheng, Kexin Chen, Matti Nykter, Jonathan Trent, Nancy Ratner, Dina C. Lev, Wei Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (24): 7563–7573.
https://doi.org/10.1158/1078-0432.CCR-11-1707
Published: 18 December 2011
View article titled, Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment
Open the PDF for Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment in another window
Includes: Supplementary data
Journal Articles

Gene Expression Analysis Identifies Potential Biomarkers of Neurofibromatosis Type 1 Including Adrenomedullin

Trent R. Hummel, Walter J. Jessen, Shyra J. Miller, Lan Kluwe, Victor F. Mautner, Margaret R. Wallace, Conxi Lázaro, Grier P. Page, Paul F. Worley, Bruce J. Aronow, Elizabeth K. Schorry, Nancy Ratner
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (20): 5048–5057.
https://doi.org/10.1158/1078-0432.CCR-10-0613
Published: 13 October 2010
View article titled, Gene Expression Analysis Identifies Potential Biomarkers of Neurofibromatosis Type 1 Including Adrenomedullin
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Includes: Supplementary data