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Journal Articles

Plasma Metabolic Profiles-Based Prediction of Induction Chemotherapy Efficacy in Nasopharyngeal Carcinoma: Results of a Bidirectional Clinical Trial

Tingxi Tang, Zhenhua Zhou, Min Chen, Nan Li, Jianda Sun, Zekai Chen, Ting Xiao, Xiaoqing Wang, Longshan Zhang, Yingqiao Wang, Hanbin Zhang, Xiuting Zheng, Bei Chen, Feng Ye, Jian Guan
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (14): 2925–2936.
https://doi.org/10.1158/1078-0432.CCR-23-3608
Published: 15 July 2024
View article titled, Plasma Metabolic Profiles-Based Prediction of Induction Chemotherapy Efficacy in Nasopharyngeal Carcinoma: Results of a Bidirectional Clinical Trial
Open the PDF for Plasma Metabolic Profiles-Based Prediction of Induction Chemotherapy Efficacy in Nasopharyngeal Carcinoma: Results of a Bidirectional Clinical Trial in another window
Includes: Supplementary data
Journal Articles

First-in-Human Study of the Radioligand 68Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma

Xiaojiang Duan, Lei Xia, Zhuochen Zhang, Yanan Ren, Martin G. Pomper, Steven P. Rowe, Xuesong Li, Nan Li, Ning Zhang, Hua Zhu, Zhi Yang, Xinan Sheng, Xing Yang
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (17): 3395–3407.
https://doi.org/10.1158/1078-0432.CCR-23-0609
Published: 01 September 2023
View article titled, First-in-Human Study of the Radioligand <sup>68</sup>Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma
Open the PDF for First-in-Human Study of the Radioligand <sup>68</sup>Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma in another window
Includes: Multimedia, Supplementary data
Journal Articles

Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric BRAFV600E Brain Tumor Models

Fuyang Li, Kathryn M. Bondra, Samson Ghilu, Adam Studebaker, Qianqian Liu, Joel E. Michalek, Mari Kogiso, Xiao-Nan Li, John A. Kalapurakal, C. David James, Sandeep Burma, Raushan T. Kurmasheva, Peter J. Houghton
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (17): 3836–3849.
https://doi.org/10.1158/1078-0432.CCR-22-1052
Published: 01 September 2022
View article titled, Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric <em>BRAF<sup>V600E</sup></em> Brain Tumor Models
Open the PDF for Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric <em>BRAF<sup>V600E</sup></em> Brain Tumor Models in another window
Includes: Supplementary data
Journal Articles

lncRNA THAP9-AS1 Promotes Pancreatic Ductal Adenocarcinoma Growth and Leads to a Poor Clinical Outcome via Sponging miR-484 and Interacting with YAP

Nan Li, Guohua Yang, Liyun Luo, Li Ling, Xiaorong Wang, Lejuan Shi, Junsong Lan, Xiaoting Jia, Qiong Zhang, Ze Long, Jinbao Liu, Weimin Hu, Zhimin He, Haiying Liu, Wanqing Liu, Guopei Zheng
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (7): 1736–1748.
https://doi.org/10.1158/1078-0432.CCR-19-0674
Published: 01 April 2020
View article titled, lncRNA <em>THAP9-AS1</em> Promotes Pancreatic Ductal Adenocarcinoma Growth and Leads to a Poor Clinical Outcome via Sponging miR-484 and Interacting with YAP
Open the PDF for lncRNA <em>THAP9-AS1</em> Promotes Pancreatic Ductal Adenocarcinoma Growth and Leads to a Poor Clinical Outcome via Sponging miR-484 and Interacting with YAP in another window
Includes: Supplementary data
Journal Articles

Mutant LKB1 Confers Enhanced Radiosensitization in Combination with Trametinib in KRAS-Mutant Non–Small Cell Lung Cancer

Yifan Wang, Nan Li, Wen Jiang, Weiye Deng, Rui Ye, Cai Xu, Yawei Qiao, Amrish Sharma, Ming Zhang, Mien-Chie Hung, Steven H. Lin
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (22): 5744–5756.
https://doi.org/10.1158/1078-0432.CCR-18-1489
Published: 15 November 2018
View article titled, Mutant LKB1 Confers Enhanced Radiosensitization in Combination with Trametinib in KRAS-Mutant Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models

Mari Kogiso, Lin Qi, Frank K. Braun, Sarah G. Injac, Linna Zhang, Yuchen Du, Huiyuan Zhang, Frank Y. Lin, Sibo Zhao, Holly Lindsay, Jack M. Su, Patricia A. Baxter, Adekunle M. Adesina, Debra Liao, Mark G. Qian, Stacey Berg, Jodi A. Muscal, Xiao-Nan Li
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (9): 2159–2170.
https://doi.org/10.1158/1078-0432.CCR-17-2256
Published: 30 April 2018
View article titled, Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models
Open the PDF for Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models in another window
Includes: Supplementary data
Journal Articles

HSP27-Mediated Extracellular and Intracellular Signaling Pathways Synergistically Confer Chemoresistance in Squamous Cell Carcinoma of Tongue

Guopei Zheng, Zhijie Zhang, Hao Liu, Yan Xiong, Liyun Luo, Xiaoting Jia, Cong Peng, Qiong Zhang, Nan Li, Yixue Gu, Minying Lu, Ying Song, Hao Pan, Jinbao Liu, Wanqing Liu, Zhimin He
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (5): 1163–1175.
https://doi.org/10.1158/1078-0432.CCR-17-2619
Published: 28 February 2018
View article titled, HSP27-Mediated Extracellular and Intracellular Signaling Pathways Synergistically Confer Chemoresistance in Squamous Cell Carcinoma of Tongue
Open the PDF for HSP27-Mediated Extracellular and Intracellular Signaling Pathways Synergistically Confer Chemoresistance in Squamous Cell Carcinoma of Tongue in another window
Includes: Supplementary data
Journal Articles

RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non–small Cell Lung Cancer

Yifan Wang, Jayanthi Gudikote, Uma Giri, Jun Yan, Weiye Deng, Rui Ye, Wen Jiang, Nan Li, Brian P. Hobbs, Jing Wang, Stephen G. Swisher, Junya Fujimoto, Ignacio I. Wistuba, Ritsuko Komaki, John V. Heymach, Steven H. Lin
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (2): 341–350.
https://doi.org/10.1158/1078-0432.CCR-17-1455
Published: 15 January 2018
View article titled, RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non–small Cell Lung Cancer
Open the PDF for RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non–small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract A07: Molecular characterization of patient-derived xenograft models of pediatric brain tumors

Sebastian Brabetz, Huriye Seker-Cin, Susanne N. Gröbner, Norman L. Mack, Volker Hovestadt, David T. W. Jones, Till Milde, Madison T. Wise, Jessica M. Rusert, Kyle Pedro, Karina Bloom, Xiao-Nan Li, Robert J. Wechsler-Reya, James M. Olson, Stefan M. Pfister, Marcel Kool
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): A07.
https://doi.org/10.1158/1557-3265.PDX16-A07
Published: 15 August 2016
View article titled, Abstract A07: Molecular characterization of patient-derived xenograft models of pediatric brain tumors
Journal Articles

Abstract B37: Chemi-genomic analysis of patient-derived xenografts to identify personalized therapies for medulloblastoma

Jessica M. Rusert, Alexandra Garancher, Yoko T. Udaka, Sebastian Brabetz, Lourdes A. Esparza, Huriye Seker-Cin, Lin Qi, Mari Kogiso, Simone Schubert, Till Milde, Yoon-Jae Cho, Xiao-Nan Li, James M. Olson, John R. Crawford, Michael L. Levy, Marcel Kool, Stefan M. Pfister, Robert J. Wechsler-Reya
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): B37.
https://doi.org/10.1158/1557-3265.PDX16-B37
Published: 15 August 2016
View article titled, Abstract B37: Chemi-genomic analysis of patient-derived xenografts to identify personalized therapies for medulloblastoma
Journal Articles

ICAM-1–Related Noncoding RNA in Cancer Stem Cells Maintains ICAM-1 Expression in Hepatocellular Carcinoma

Weixing Guo, Shupeng Liu, Yuqiang Cheng, Lei Lu, Jie Shi, Guixia Xu, Nan Li, Kai Cheng, Mengchao Wu, Shuqun Cheng, Shanrong Liu
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (8): 2041–2050.
https://doi.org/10.1158/1078-0432.CCR-14-3106
Published: 14 April 2016
View article titled, ICAM-1–Related Noncoding RNA in Cancer Stem Cells Maintains ICAM-1 Expression in Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Phase 1 Study of Valproic Acid in Pediatric Patients with Refractory Solid or CNS Tumors: A Children's Oncology Group Report

Jack M. Su, Xiao-Nan Li, Patrick Thompson, Ching-Nan Ou, Ashish M. Ingle, Heidi Russell, Ching C. Lau, Peter C. Adamson, Susan M. Blaney
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (3): 589–597.
https://doi.org/10.1158/1078-0432.CCR-10-0738
Published: 01 February 2011
View article titled, Phase 1 Study of Valproic Acid in Pediatric Patients with Refractory Solid or CNS Tumors: A Children's Oncology Group Report
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Journal Articles

Up-regulation of Tumor Susceptibility Gene 101 Conveys Poor Prognosis through Suppression of p21 Expression in Ovarian Cancer

Travis W. Young, Daniel G. Rosen, Fang C. Mei, Nan Li, Jinsong Liu, Xiao-Fan Wang, Xiaodong Cheng
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (13): 3848–3854.
https://doi.org/10.1158/1078-0432.CCR-07-0337
Published: 02 July 2007
View article titled, Up-regulation of Tumor Susceptibility Gene 101 Conveys Poor Prognosis through Suppression of p21 Expression in Ovarian Cancer
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Journal Articles

Valproic Acid Prolongs Survival Time of Severe Combined Immunodeficient Mice Bearing Intracerebellar Orthotopic Medulloblastoma Xenografts

Qin Shu, Barbara Antalffy, Jack Meng Feng Su, Adekunle Adesina, Ching-Nan Ou, Torsten Pietsch, Susan M. Blaney, Ching C. Lau, Xiao-Nan Li
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (15): 4687–4694.
https://doi.org/10.1158/1078-0432.CCR-05-2849
Published: 09 August 2006
View article titled, Valproic Acid Prolongs Survival Time of Severe Combined Immunodeficient Mice Bearing Intracerebellar Orthotopic Medulloblastoma Xenografts
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Journal Articles

Silencing of Human Phosphatidylethanolamine-Binding Protein 4 Sensitizes Breast Cancer Cells to Tumor Necrosis Factor-α–Induced Apoptosis and Cell Growth Arrest

Xiaojian Wang, Nan Li, Hongzhe Li, Bin Liu, Jianming Qiu, Taoyong Chen, Xuetao Cao
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (20): 7545–7553.
https://doi.org/10.1158/1078-0432.CCR-05-0879
Published: 20 October 2005
View article titled, Silencing of Human Phosphatidylethanolamine-Binding Protein 4 Sensitizes Breast Cancer Cells to Tumor Necrosis Factor-α–Induced Apoptosis and Cell Growth Arrest
Open the PDF for Silencing of Human Phosphatidylethanolamine-Binding Protein 4 Sensitizes Breast Cancer Cells to Tumor Necrosis Factor-α–Induced Apoptosis and Cell Growth Arrest in another window
Includes: Supplementary data
Journal Articles

Phenylbutyrate and Phenylacetate Induce Differentiation and Inhibit Proliferation of Human Medulloblastoma Cells

Xiao-Nan Li, Suhag Parikh, Qin Shu, Hye-Lim Jung, Chi-Wan Chow, Laszlo Perlaky, Hon-Chiu Eastwood Leung, Jack Su, Susan Blaney, Ching C. Lau
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (3): 1150–1159.
https://doi.org/10.1158/1078-0432.CCR-0747-3
Published: 10 February 2004
View article titled, Phenylbutyrate and Phenylacetate Induce Differentiation and Inhibit Proliferation of Human Medulloblastoma Cells
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Journal Articles

Augmentation of Sodium Butyrate-induced Apoptosis by Phosphatidylinositol 3′-Kinase Inhibition in the KM20 Human Colon Cancer Cell Line

Qingding Wang, Nan Li, Xiaofu Wang, Myung M. Kim, B. Mark Evers
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (6): 1940–1947.
Published: 01 June 2002
View article titled, Augmentation of Sodium Butyrate-induced Apoptosis by Phosphatidylinositol 3′-Kinase Inhibition in the KM20 Human Colon Cancer Cell Line
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Journal Articles

Genetic Approach to Insight into the Immunobiology of Human Dendritic Cells and Identification of CD84-H1, a Novel CD84 Homologue

Weiping Zhang, Tao Wan, Nan Li, Zhenglong Yuan, Long He, Xuejun Zhu, Min Yu, Xuetao Cao
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (3): 822s–829s.
Published: 01 March 2001
View article titled, Genetic Approach to Insight into the Immunobiology of Human Dendritic Cells and Identification of CD84-H1, a Novel CD84 Homologue
Open the PDF for Genetic Approach to Insight into the Immunobiology of Human Dendritic Cells and Identification of CD84-H1, a Novel CD84 Homologue in another window