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Naema Nayyar
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Journal Articles

CDK4/6 Inhibition Sensitizes Intracranial Tumors to PD-1 Blockade in Preclinical Models of Brain Metastasis

Naema Nayyar, Magali A. de Sauvage, Jane Chuprin, Emily M. Sullivan, Mohini Singh, Consuelo Torrini, Britney S. Zhang, Sushobhana Bandyopadhyay, Keith A. Daniels, Christopher Alvarez-Breckenridge, Ashish Dahal, Michael A. Brehm, Priscilla K. Brastianos
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (2): 420–435.
https://doi.org/10.1158/1078-0432.CCR-23-0433
Published: 17 January 2024
View article titled, CDK4/6 Inhibition Sensitizes Intracranial Tumors to PD-1 Blockade in Preclinical Models of Brain Metastasis
Open the PDF for CDK4/6 Inhibition Sensitizes Intracranial Tumors to PD-1 Blockade in Preclinical Models of Brain Metastasis in another window
Includes: Supplementary data
Journal Articles

Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non–Small Cell Lung Cancer

Joshua K. Sabari, Vamsidhar Velcheti, Kazuhide Shimizu, Matthew R. Strickland, Rebecca S. Heist, Mohini Singh, Naema Nayyar, Anita Giobbie-Hurder, Subba R. Digumarthy, Justin F. Gainor, Anant P. Rajan, Edwin Nieblas-Bedolla, Aaron C. Burns, Jill Hallin, Peter Olson, James G. Christensen, Sylvia C. Kurz, Priscilla K. Brastianos, Hiroaki Wakimoto
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (15): 3318–3328.
https://doi.org/10.1158/1078-0432.CCR-22-0383
Published: 02 August 2022
View article titled, Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRAS<sup>G12C</sup>-Mutant Non–Small Cell Lung Cancer
Open the PDF for Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRAS<sup>G12C</sup>-Mutant Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Alterations in Pericyte Subpopulations Are Associated with Elevated Blood–Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer

L. Tiffany Lyle, Paul R. Lockman, Chris E. Adkins, Afroz Shareef Mohammad, Emily Sechrest, Emily Hua, Diane Palmieri, David J. Liewehr, Seth M. Steinberg, Wojciech Kloc, Ewa Izycka-Swieszewska, Renata Duchnowska, Naema Nayyar, Priscilla K. Brastianos, Patricia S. Steeg, Brunilde Gril
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (21): 5287–5299.
https://doi.org/10.1158/1078-0432.CCR-15-1836
Published: 31 October 2016
View article titled, Alterations in Pericyte Subpopulations Are Associated with Elevated Blood–Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer
Open the PDF for Alterations in Pericyte Subpopulations Are Associated with Elevated Blood–Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer in another window
Includes: Supplementary data