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Nadia Luheshi
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Journal Articles

Design and Preclinical Evaluation of a Novel B7-H4–Directed Antibody–Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305

Krista Kinneer, Philipp Wortmann, Zachary A. Cooper, Niall J. Dickinson, Luke Masterson, Thais Cailleau, Ian Hutchinson, Balakumar Vijayakrishnan, Mary McFarlane, Kathryn Ball, Michael Davies, Arthur Lewis, Yue Huang, Anton I. Rosenbaum, Jiaqi Yuan, Jon Chesebrough, Judith Anderton, Noel Monks, Steven Novick, Jixin Wang, Nazzareno Dimasi, R. James Christie, Darrin Sabol, Frances Anne Tosto, Yann Wallez, Elisabetta Leo, Mark R. Albertella, Anna D. Staniszewska, David A. Tice, Philip W. Howard, Nadia Luheshi, Puja Sapra
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (6): 1086–1101.
https://doi.org/10.1158/1078-0432.CCR-22-2630
Published: 14 March 2023
View article titled, Design and Preclinical Evaluation of a Novel B7-H4–Directed Antibody–Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305
Open the PDF for Design and Preclinical Evaluation of a Novel B7-H4–Directed Antibody–Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305 in another window
Includes: Supplementary data
Journal Articles

Intratumoral IL12 mRNA Therapy Promotes TH1 Transformation of the Tumor Microenvironment

Susannah L. Hewitt, Dyane Bailey, John Zielinski, Ameya Apte, Faith Musenge, Russell Karp, Shannon Burke, Fabien Garcon, Ankita Mishra, Sushma Gurumurthy, Amanda Watkins, Kristen Arnold, James Moynihan, Eleanor Clancy-Thompson, Kathy Mulgrew, Grace Adjei, Katharina Deschler, Darren Potz, Gordon Moody, David A. Leinster, Steve Novick, Michal Sulikowski, Chris Bagnall, Philip Martin, Jean-Martin Lapointe, Han Si, Chris Morehouse, Maja Sedic, Robert W. Wilkinson, Ronald Herbst, Joshua P. Frederick, Nadia Luheshi
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (23): 6284–6298.
https://doi.org/10.1158/1078-0432.CCR-20-0472
Published: 01 December 2020
View article titled, Intratumoral IL12 mRNA Therapy Promotes TH1 Transformation of the Tumor Microenvironment
Open the PDF for Intratumoral IL12 mRNA Therapy Promotes TH1 Transformation of the Tumor Microenvironment in another window
Includes: Supplementary data