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Journal Articles

Structural Variants at the BRCA1/2 Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma

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Ailith Ewing, Alison Meynert, Michael Churchman, Graeme R. Grimes, Robert L. Hollis, C. Simon Herrington, Tzyvia Rye, Clare Bartos, Ian Croy, Michelle Ferguson, Mairi Lennie, Trevor McGoldrick, Neil McPhail, Nadeem Siddiqui, Suzanne Dowson, Rosalind Glasspool, Melanie Mackean, Fiona Nussey, Brian McDade, Darren Ennis, Lynn McMahon, Athena Matakidou, Brian Dougherty, Ruth March, J. Carl Barrett, Iain A. McNeish, for the Scottish Genomes Partnership, Andrew V. Biankin, Patricia Roxburgh, Charlie Gourley, Colin A. Semple
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (11): 3201–3214.
https://doi.org/10.1158/1078-0432.CCR-20-4068
Published: 01 June 2021
View articletitled, Structural Variants at the BRCA1/2 Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma
Open the PDF for Structural Variants at the BRCA1/2 Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma in another window
Includes: Supplementary data
Journal Articles

Platinum-Based Chemotherapy Induces Methylation Changes in Blood DNA Associated with Overall Survival in Patients with Ovarian Cancer

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James M. Flanagan, Angela Wilson, Chail Koo, Nahal Masrour, John Gallon, Erick Loomis, Kirsty Flower, Charlotte Wilhelm-Benartzi, Alexander Hergovich, Paula Cunnea, Hani Gabra, Elena Ioana Braicu, Jalid Sehouli, Silvia Darb-Esfahani, Adriaan Vanderstichele, Ignace Vergote, Caroline Kreuzinger, Dan Cacsire Castillo-Tong, G. Bea A. Wisman, Els MJJ Berns, Nadeem Siddiqui, James Paul, Robert Brown
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (9): 2213–2222.
https://doi.org/10.1158/1078-0432.CCR-16-1754
Published: 30 April 2017
View articletitled, Platinum-Based Chemotherapy Induces Methylation Changes in Blood DNA Associated with Overall Survival in Patients with Ovarian Cancer
Open the PDF for Platinum-Based Chemotherapy Induces Methylation Changes in Blood DNA Associated with Overall Survival in Patients with Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium

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Sharon E. Johnatty, Jonathan P. Tyrer, Siddhartha Kar, Jonathan Beesley, Yi Lu, Bo Gao, Peter A. Fasching, Alexander Hein, Arif B. Ekici, Matthias W. Beckmann, Diether Lambrechts, Els Van Nieuwenhuysen, Ignace Vergote, Sandrina Lambrechts, Mary Anne Rossing, Jennifer A. Doherty, Jenny Chang-Claude, Francesmary Modugno, Roberta B. Ness, Kirsten B. Moysich, Douglas A. Levine, Lambertus A. Kiemeney, Leon F.A.G. Massuger, Jacek Gronwald, Jan Lubiński, Anna Jakubowska, Cezary Cybulski, Louise Brinton, Jolanta Lissowska, Nicolas Wentzensen, Honglin Song, Valerie Rhenius, Ian Campbell, Diana Eccles, Weiva Sieh, Alice S. Whittemore, Valerie McGuire, Joseph H. Rothstein, Rebecca Sutphen, Hoda Anton-Culver, Argyrios Ziogas, Simon A. Gayther, Aleksandra Gentry-Maharaj, Usha Menon, Susan J. Ramus, Celeste L. Pearce, Malcolm C. Pike, Daniel O. Stram, Anna H. Wu, Jolanta Kupryjanczyk, Agnieszka Dansonka-Mieszkowska, Iwona K. Rzepecka, Beata Spiewankiewicz, Marc T. Goodman, Lynne R. Wilkens, Michael E. Carney, Pamela J. Thompson, Florian Heitz, Andreas du Bois, Ira Schwaab, Philipp Harter, Jacobus Pisterer, Peter Hillemanns, on behalf of the AGO Study Group, Beth Y. Karlan, Christine Walsh, Jenny Lester, Sandra Orsulic, Stacey J. Winham, Madalene Earp, Melissa C. Larson, Zachary C. Fogarty, Estrid Høgdall, Allan Jensen, Susanne Kruger Kjaer, Brooke L. Fridley, Julie M. Cunningham, Robert A. Vierkant, Joellen M. Schildkraut, Edwin S. Iversen, Kathryn L. Terry, Daniel W. Cramer, Elisa V. Bandera, Irene Orlow, Tanja Pejovic, Yukie Bean, Claus Høgdall, Lene Lundvall, Ian McNeish, James Paul, Karen Carty, Nadeem Siddiqui, Rosalind Glasspool, Thomas Sellers, Catherine Kennedy, Yoke-Eng Chiew, Andrew Berchuck, Stuart MacGregor, Paul D.P. Pharoah, Ellen L. Goode, Anna deFazio, Penelope M. Webb, Georgia Chenevix-Trench
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (23): 5264–5276.
https://doi.org/10.1158/1078-0432.CCR-15-0632
Published: 30 November 2015
View articletitled, Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium
Open the PDF for Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium in another window
Includes: Supplementary data
Journal Articles

Promoter CpG Island Methylation of Genes in Key Cancer Pathways Associates with Clinical Outcome in High-Grade Serous Ovarian Cancer

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Wei Dai, Constanze Zeller, Nahal Masrour, Nadeem Siddiqui, James Paul, Robert Brown
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (20): 5788–5797.
https://doi.org/10.1158/1078-0432.CCR-13-1217
Published: 14 October 2013
View articletitled, Promoter CpG Island Methylation of Genes in Key Cancer Pathways Associates with Clinical Outcome in High-Grade Serous Ovarian Cancer
Open the PDF for Promoter CpG Island Methylation of Genes in Key Cancer Pathways Associates with Clinical Outcome in High-Grade Serous Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Systematic CpG Islands Methylation Profiling of Genes in the Wnt Pathway in Epithelial Ovarian Cancer Identifies Biomarkers of Progression-Free Survival

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Wei Dai, Jens M. Teodoridis, Constanze Zeller, Janet Graham, Jenny Hersey, James M. Flanagan, Euan Stronach, David W. Millan, Nadeem Siddiqui, Jim Paul, Robert Brown
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (12): 4052–4062.
https://doi.org/10.1158/1078-0432.CCR-10-3021
Published: 15 June 2011
View articletitled, Systematic CpG Islands Methylation Profiling of Genes in the Wnt Pathway in Epithelial Ovarian Cancer Identifies Biomarkers of Progression-Free Survival
Open the PDF for Systematic CpG Islands Methylation Profiling of Genes in the Wnt Pathway in Epithelial Ovarian Cancer Identifies Biomarkers of Progression-Free Survival in another window
Includes: Supplementary data