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Moshe Talpaz
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Journal Articles

Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations

Malathi Kandarpa, Dan Robinson, Yi-Mi Wu, Tingting Qin, Kristen Pettit, Qing Li, Gary Luker, Maureen Sartor, Arul Chinnaiyan, Moshe Talpaz
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (9): 1972–1983.
https://doi.org/10.1158/1078-0432.CCR-23-0372
Published: 01 May 2024
View article titled, Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations
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Includes: Supplementary data
Journal Articles

A Phase Ib Trial of AVID200, a TGFβ 1/3 Trap, in Patients with Myelofibrosis

John Mascarenhas, Anna Rita Migliaccio, Heidi Kosiorek, Rupali Bhave, Jeanne Palmer, Andrew Kuykendall, Ruben Mesa, Raajit K. Rampal, Aaron T. Gerds, Abdulraheem Yacoub, Kristen Pettit, Moshe Talpaz, Rami Komrokji, Marina Kremyanskaya, Agapito Gonzalez, Frank Fabris, Kathryn Johnson, Mikaela Dougherty, Erin McGovern, Juan Arango Ossa, Dylan Domenico, Noushin Farnoud, Rona Singer Weinberg, Amy Kong, Vesna Najfeld, Alessandro Maria Vannucchi, Francesca Arciprete, Maria Zingariello, Mario Falchi, Mohamed E. Salama, Carolyn Mead-Harvey, Amylou Dueck, Lilian Varricchio, Ronald Hoffman
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (18): 3622–3632.
https://doi.org/10.1158/1078-0432.CCR-23-0276
Published: 15 September 2023
View article titled, A Phase Ib Trial of AVID200, a TGFβ 1/3 Trap, in Patients with Myelofibrosis
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Includes: Supplementary data
Journal Articles

Abstract 10: Precision medicine strategy to elucidate and target Bcl-2 prosurvival proteins in a wide spectrum of cancers

Karson J. Kump, Matthew Lieberman, Rita A. Avelar, Charles Foucar, Malathi Kandarpa, Antonio Di Cristofano, Russell J. Ryan, Sami N. Malek, Ryan A. Wilcox, Dale L. Bixby, Tycel J. Phillips, Moshe Talpaz, Analisa DiFeo, Zaneta Nikolovska-Coleska
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (12_Supplement_1): 10.
https://doi.org/10.1158/1557-3265.ADVPRECMED20-10
Published: 15 June 2020
View article titled, Abstract 10: Precision medicine strategy to elucidate and target Bcl-2 prosurvival proteins in a wide spectrum of cancers
Journal Articles

Development of 2 Bromodomain and Extraterminal Inhibitors With Distinct Pharmacokinetic and Pharmacodynamic Profiles for the Treatment of Advanced Malignancies

Gerald Falchook, Seth Rosen, Patricia LoRusso, Justin Watts, Shilpa Gupta, Catherine C. Coombs, Moshe Talpaz, Razelle Kurzrock, Monica Mita, Ryan Cassaday, Wael Harb, Julio Peguero, David C. Smith, Sarina A. Piha-Paul, Russ Szmulewitz, Marcus S. Noel, Swamy Yeleswaram, Phillip Liu, Julie Switzky, Gongfu Zhou, Fred Zheng, Amitkumar Mehta
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (6): 1247–1257.
https://doi.org/10.1158/1078-0432.CCR-18-4071
Published: 13 March 2020
View article titled, Development of 2 Bromodomain and Extraterminal Inhibitors With Distinct Pharmacokinetic and Pharmacodynamic Profiles for the Treatment of Advanced Malignancies
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Includes: Supplementary data
Journal Articles

NF1 Inactivation in Adult Acute Myelogenous Leukemia

Brian Parkin, Peter Ouillette, Yin Wang, Yan Liu, Whitney Wright, Diane Roulston, Anjali Purkayastha, Amanda Dressel, Judith Karp, Paula Bockenstedt, Ammar Al-Zoubi, Moshe Talpaz, Lisa Kujawski, Yang Liu, Kerby Shedden, Sajid Shakhan, Cheng Li, Harry Erba, Sami N. Malek
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (16): 4135–4147.
https://doi.org/10.1158/1078-0432.CCR-09-2639
Published: 11 August 2010
View article titled, NF1 Inactivation in Adult Acute Myelogenous Leukemia
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Includes: Supplementary data
Journal Articles

Quality of Reporting of Serious Adverse Drug Events to an Institutional Review Board: A Case Study with the Novel Cancer Agent, Imatinib Mesylate

David A. Dorr, Rachel Burdon, Dennis P. West, Jennifer Lagman, Christina Georgopoulos, Steven M. Belknap, June M. McKoy, Benjamin Djulbegovic, Beatrice J. Edwards, Sigmund A. Weitzman, Simone Boyle, Martin S. Tallman, Moshe Talpaz, Oliver Sartor, Charles L. Bennett
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (11): 3850–3855.
https://doi.org/10.1158/1078-0432.CCR-08-1811
Published: 01 June 2009
View article titled, Quality of Reporting of Serious Adverse Drug Events to an Institutional Review Board: A Case Study with the Novel Cancer Agent, Imatinib Mesylate
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Includes: Supplementary data
Journal Articles

Dasatinib (BMS-354825) Tyrosine Kinase Inhibitor Suppresses Invasion and Induces Cell Cycle Arrest and Apoptosis of Head and Neck Squamous Cell Carcinoma and Non–Small Cell Lung Cancer Cells

Faye M. Johnson, Babita Saigal, Moshe Talpaz, Nicholas J. Donato
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (19): 6924–6932.
https://doi.org/10.1158/1078-0432.CCR-05-0757
Published: 03 October 2005
View article titled, Dasatinib (BMS-354825) Tyrosine Kinase Inhibitor Suppresses Invasion and Induces Cell Cycle Arrest and Apoptosis of Head and Neck Squamous Cell Carcinoma and Non–Small Cell Lung Cancer Cells
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Journal Articles

Phase I Evaluation of a 40-kDa Branched-Chain Long-Acting Pegylated IFN-α-2a With and Without Cytarabine in Patients with Chronic Myelogenous Leukemia

Moshe Talpaz, Ashok Rakhit, Karen Rittweger, Susan O'Brien, Jorge Cortes, Scott Fettner, Leon Hooftman, Hagop Kantarjian
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (17): 6247–6255.
https://doi.org/10.1158/1078-0432.CCR-05-0882
Published: 06 September 2005
View article titled, Phase I Evaluation of a 40-kDa Branched-Chain Long-Acting Pegylated IFN-α-2a With and Without Cytarabine in Patients with Chronic Myelogenous Leukemia
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Journal Articles

Molecular Responses in Patients with Chronic Myelogenous Leukemia in Chronic Phase Treated with Imatinib Mesylate

Jorge Cortes, Moshe Talpaz, Susan O'Brien, Dan Jones, Rajyalakshmi Luthra, Jenny Shan, Francis Giles, Stefan Faderl, Srdan Verstovsek, Guillermo Garcia-Manero, Mary B. Rios, Hagop Kantarjian
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (9): 3425–3432.
https://doi.org/10.1158/1078-0432.CCR-04-2139
Published: 02 May 2005
View article titled, Molecular Responses in Patients with Chronic Myelogenous Leukemia in Chronic Phase Treated with Imatinib Mesylate
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Journal Articles

Survival Advantage with Imatinib Mesylate Therapy in Chronic-Phase Chronic Myelogenous Leukemia (CML-CP) after IFN-α Failure and in Late CML-CP, Comparison with Historical Controls

Hagop Kantarjian, Susan O’Brien, Jorge Cortes, Francis Giles, Jianqin Shan, Mary Beth Rios, Stefan Faderl, Srdan Verstovsek, Guillermo Garcia-Manero, William Wierda, Steven Kornblau, Alessandra Ferrajoli, Michael Keating, Moshe Talpaz
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (1): 68–75.
https://doi.org/10.1158/1078-0432.CCR-1035-3
Published: 20 January 2004
View article titled, Survival Advantage with Imatinib Mesylate Therapy in Chronic-Phase Chronic Myelogenous Leukemia (CML-CP) after IFN-α Failure and in Late CML-CP, Comparison with Historical Controls
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Journal Articles

Impact of p210Bcr-Abl on Ultraviolet C Wavelength-induced DNA Damage and Repair

Eunice Laurent, David L. Mitchell, Zeev Estrov, Megan Lowery, Susan L. Tucker, Moshe Talpaz, Razelle Kurzrock
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (10): 3722–3730.
Published: 23 September 2003
View article titled, Impact of p210<sup>Bcr-Abl</sup> on Ultraviolet C Wavelength-induced DNA Damage and Repair
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Journal Articles

Development of Varicella-Zoster Virus Infection in Patients with Chronic Myelogenous Leukemia Treated with Imatinib Mesylate

Gloria N. Mattiuzzi, Jorge E. Cortes, Moshe Talpaz, James Reuben, Mary Beth Rios, Jianjin Shan, Dimitrios Kontoyiannis, Francis J. Giles, Issam Raad, Srdan Verstovsek, Alessandra Ferrajoli, Hagop M. Kantarjian
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (3): 976–980.
Published: 01 March 2003
View article titled, Development of Varicella-Zoster Virus Infection in Patients with Chronic Myelogenous Leukemia Treated with Imatinib Mesylate
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Journal Articles

Modulation of Cellular Signaling Pathways: Prospects for Targeted Therapy in Hematological Malignancies

Farhad Ravandi, Moshe Talpaz, Zeev Estrov
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (2): 535–550.
Published: 01 February 2003
View article titled, Modulation of Cellular Signaling Pathways: <subtitle>Prospects for Targeted Therapy in Hematological Malignancies</subtitle>
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Journal Articles

Quantitative Polymerase Chain Reaction Monitoring of BCR-ABL during Therapy with Imatinib Mesylate (STI571; Gleevec) in Chronic-Phase Chronic Myelogenous Leukemia

Hagop M. Kantarjian, Moshe Talpaz, Jorge Cortes, Susan O’Brien, Stefan Faderl, Deborah Thomas, Francis Giles, Mary Beth Rios, Jianqin Shan, Ralph Arlinghaus
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (1): 160–166.
Published: 01 January 2003
View article titled, Quantitative Polymerase Chain Reaction Monitoring of <em>BCR-ABL</em> during Therapy with Imatinib Mesylate (STI571; Gleevec) in Chronic-Phase Chronic Myelogenous Leukemia
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Journal Articles

Imatinib Mesylate for Philadelphia Chromosome-positive, Chronic-Phase Myeloid Leukemia after Failure of Interferon-α: Follow-Up Results

Hagop M. Kantarjian, Moshe Talpaz, Susan O’Brien, Terry L. Smith, Francis J. Giles, Stefan Faderl, Deborah A. Thomas, Guillermo Garcia-Manero, Jean-Pierre J. Issa, Michael Andreeff, Steven M. Kornblau, Charles Koller, Milosav Beran, Michael Keating, Mary Beth Rios, Jenny Shan, Debra Resta, Renaud Capdeville, Kimberly Hayes, Maher Albitar, Emil J. Freireich, Jorge E. Cortes
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (7): 2177–2187.
Published: 01 July 2002
View article titled, Imatinib Mesylate for Philadelphia Chromosome-positive, Chronic-Phase Myeloid Leukemia after Failure of Interferon-α: <subtitle>Follow-Up Results</subtitle>
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Journal Articles

Treatment of Philadelphia Chromosome-positive, Accelerated-phase Chronic Myelogenous Leukemia with Imatinib Mesylate

Hagop M. Kantarjian, Susan O’Brien, Jorge E. Cortes, Terry L. Smith, Mary Beth Rios, Jianqin Shan, Ying Yang, Francis J. Giles, Deborah A. Thomas, Stefan Faderl, Guillermo Garcia-Manero, Sima Jeha, William Wierda, Jean-Pierre J. Issa, Steven M. Kornblau, Michael Keating, Debra Resta, Renaud Capdeville, Moshe Talpaz
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (7): 2167–2176.
Published: 01 July 2002
View article titled, Treatment of Philadelphia Chromosome-positive, Accelerated-phase Chronic Myelogenous Leukemia with Imatinib Mesylate
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Journal Articles

Clinical Use of Tyrosine Kinase Inhibitors: Therapy for Chronic Myelogenous Leukemia and Other Cancers

Nicholas J. Donato, Moshe Talpaz
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (8): 2965–2966.
Published: 01 August 2000
View article titled, Clinical Use of Tyrosine Kinase Inhibitors: Therapy for Chronic Myelogenous Leukemia and Other Cancers
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Journal Articles

Restoration of Th1 Cytokine Synthesis by T Cells of Patients with Chronic Myelogenous Leukemia in Cytogenetic and Hematologic Remission with Interferon-α

James M. Reuben, Bang-Ning Lee, Hannah Johnson, Herbert Fritsche, Hagop M. Kantarjian, Moshe Talpaz
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (5): 1671–1677.
Published: 01 May 2000
View article titled, Restoration of Th1 Cytokine Synthesis by T Cells of Patients with Chronic Myelogenous Leukemia in Cytogenetic and Hematologic Remission with Interferon-α
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Journal Articles

Serum β-2 Microglobulin Levels Are a Significant Prognostic Factor in Philadelphia Chromosome-positive Chronic Myelogenous Leukemia

Jose Rodriguez, Jorge Cortes, Moshe Talpaz, Susan O’Brien, Terry L. Smith, Mary Beth Rios, Hagop Kantarjian
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (1): 147–152.
Published: 01 January 2000
View article titled, Serum β-2 Microglobulin Levels Are a Significant Prognostic Factor in Philadelphia Chromosome-positive Chronic Myelogenous Leukemia
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Journal Articles

Significance of FHIT Expression in Chronic Myelogenous Leukemia

Hagop M. Kantarjian, Moshe Talpaz, Susan O’Brien, Taghi Manshouri, Jorge Cortes, Francis Giles, Mary Beth Rios, Carlo M. Croce, Maher Albitar
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (12): 4059–4064.
Published: 01 December 1999
View article titled, Significance of FHIT Expression in Chronic Myelogenous Leukemia
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