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Ming Huang
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Journal Articles

Impaired Chromatin Remodeling Predicts Better Survival to Modified Gemcitabine and S-1 plus Nivolumab in Advanced Biliary Tract Cancer: A Phase II T1219 Study

Nai-Jung Chiang, Kien Thiam Tan, Li-Yuan Bai, Chin-Fu Hsiao, Chung-Yu Huang, Yi-Ping Hung, Chien-Jui Huang, San-Chi Chen, Yan-Shen Shan, Yee Chao, Yi-Hsiang Huang, I-Cheng Lee, Pei-Chang Lee, Yung-Yeh Su, Shu-Jen Chen, Chun-Nan Yeh, Li-Tzong Chen, Ming-Huang Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (19): 4248–4257.
https://doi.org/10.1158/1078-0432.CCR-22-1152
Published: 03 October 2022
View article titled, Impaired Chromatin Remodeling Predicts Better Survival to Modified Gemcitabine and S-1 plus Nivolumab in Advanced Biliary Tract Cancer: A Phase II T1219 Study
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Includes: Supplementary data
Journal Articles

Long Noncoding RNA LBCS Inhibits Self-Renewal and Chemoresistance of Bladder Cancer Stem Cells through Epigenetic Silencing of SOX2

Xu Chen, Ruihui Xie, Peng Gu, Ming Huang, Jinli Han, Wen Dong, Weibin Xie, Bo Wang, Wang He, Guangzheng Zhong, Ziyue Chen, Jian Huang, Tianxin Lin
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (4): 1389–1403.
https://doi.org/10.1158/1078-0432.CCR-18-1656
Published: 15 February 2019
View article titled, Long Noncoding RNA <em>LBCS</em> Inhibits Self-Renewal and Chemoresistance of Bladder Cancer Stem Cells through Epigenetic Silencing of SOX2
Open the PDF for Long Noncoding RNA <em>LBCS</em> Inhibits Self-Renewal and Chemoresistance of Bladder Cancer Stem Cells through Epigenetic Silencing of SOX2 in another window
Includes: Supplementary data
Journal Articles

Induction Chemotherapy plus Concurrent Chemoradiotherapy in Endemic Nasopharyngeal Carcinoma: Individual Patient Data Pooled Analysis of Four Randomized Trials

Yu-Pei Chen, Ling-Long Tang, Qi Yang, Sharon-Shuxian Poh, Edwin P. Hui, Anthony T.C. Chan, Whee-Sze Ong, Terence Tan, Joseph Wee, Wen-Fei Li, Lei Chen, Brigette B.Y. Ma, Macy Tong, Sze-Huey Tan, Shie-Lee Cheah, Kam-Weng Fong, Kiattisa Sommat, Yoke Lim Soong, Ying Guo, Ai-Hua Lin, Ying Sun, Ming-Huang Hong, Su-Mei Cao, Ming-Yuan Chen, Jun Ma
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (8): 1824–1833.
https://doi.org/10.1158/1078-0432.CCR-17-2656
Published: 12 April 2018
View article titled, Induction Chemotherapy plus Concurrent Chemoradiotherapy in Endemic Nasopharyngeal Carcinoma: Individual Patient Data Pooled Analysis of Four Randomized Trials
Open the PDF for Induction Chemotherapy plus Concurrent Chemoradiotherapy in Endemic Nasopharyngeal Carcinoma: Individual Patient Data Pooled Analysis of Four Randomized Trials in another window
Includes: Supplementary data
Journal Articles

A Prognostic Bio-Model Based on SQSTM1 and N-Stage Identifies Nasopharyngeal Carcinoma Patients at High Risk of Metastasis for Additional Induction Chemotherapy

Qi Yang, Meng-Xia Zhang, Xiong Zou, You-Ping Liu, Rui You, Tao Yu, Rou Jiang, Yi-Nuan Zhang, Jing-Yu Cao, Ming-Huang Hong, Qing Liu, Ling Guo, Tie-Bang Kang, Xiao-Feng Zhu, Ming-Yuan Chen
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (3): 648–658.
https://doi.org/10.1158/1078-0432.CCR-17-1963
Published: 31 January 2018
View article titled, A Prognostic Bio-Model Based on SQSTM1 and N-Stage Identifies Nasopharyngeal Carcinoma Patients at High Risk of Metastasis for Additional Induction Chemotherapy
Open the PDF for A Prognostic Bio-Model Based on SQSTM1 and N-Stage Identifies Nasopharyngeal Carcinoma Patients at High Risk of Metastasis for Additional Induction Chemotherapy in another window
Includes: Supplementary data
Journal Articles

Integrated Epigenomics Analysis Reveals a DNA Methylation Panel for Endometrial Cancer Detection Using Cervical Scrapings

Rui-Lan Huang, Po-Hsuan Su, Yu-Ping Liao, Tzu-I Wu, Ya-Ting Hsu, Wei-Yu Lin, Hui-Chen Wang, Yu-Chun Weng, Yu-Che Ou, Tim Hui-Ming Huang, Hung-Cheng Lai
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (1): 263–272.
https://doi.org/10.1158/1078-0432.CCR-16-0863
Published: 02 January 2017
View article titled, Integrated Epigenomics Analysis Reveals a DNA Methylation Panel for Endometrial Cancer Detection Using Cervical Scrapings
Open the PDF for Integrated Epigenomics Analysis Reveals a DNA Methylation Panel for Endometrial Cancer Detection Using Cervical Scrapings in another window
Includes: Supplementary data
Journal Articles

ALDH1A3, the Major Aldehyde Dehydrogenase Isoform in Human Cholangiocarcinoma Cells, Affects Prognosis and Gemcitabine Resistance in Cholangiocarcinoma Patients

Ming-Huang Chen, Jing-Jie Weng, Chi-Tung Cheng, Ren-Chin Wu, Shih-Chiang Huang, Chiao-En Wu, Yi-Hsiu Chung, Chun-Yu Liu, Mu-Hsin Chang, Ming-Han Chen, Kun-Chun Chiang, Ta-Sen Yeh, Yeu Su, Chun-Nan Yeh
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16): 4225–4235.
https://doi.org/10.1158/1078-0432.CCR-15-1800
Published: 14 August 2016
View article titled, ALDH1A3, the Major Aldehyde Dehydrogenase Isoform in Human Cholangiocarcinoma Cells, Affects Prognosis and Gemcitabine Resistance in Cholangiocarcinoma Patients
Open the PDF for ALDH1A3, the Major Aldehyde Dehydrogenase Isoform in Human Cholangiocarcinoma Cells, Affects Prognosis and Gemcitabine Resistance in Cholangiocarcinoma Patients in another window
Includes: Supplementary data
Journal Articles

Promoter Hypomethylation of EpCAM-Regulated Bone Morphogenetic Protein Gene Family in Recurrent Endometrial Cancer

Ya-Ting Hsu, Fei Gu, Yi-Wen Huang, Joseph Liu, Jianhua Ruan, Rui-Lan Huang, Chiou-Miin Wang, Chun-Liang Chen, Rohit R. Jadhav, Hung-Cheng Lai, David G. Mutch, Paul J. Goodfellow, Ian M. Thompson, Nameer B. Kirma, Tim Hui-Ming Huang
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (22): 6272–6285.
https://doi.org/10.1158/1078-0432.CCR-13-1734
Published: 14 November 2013
View article titled, Promoter Hypomethylation of EpCAM-Regulated <em>Bone Morphogenetic Protein</em> Gene Family in Recurrent Endometrial Cancer
Open the PDF for Promoter Hypomethylation of EpCAM-Regulated <em>Bone Morphogenetic Protein</em> Gene Family in Recurrent Endometrial Cancer in another window
Includes: Supplementary data
Journal Articles

Polymorphisms in the Endothelin-1 and Endothelin A Receptor Genes and Survival in Patients with Locoregionally Advanced Nasopharyngeal Carcinoma

Yue-Feng Wen, Bin Qi, Huai Liu, Hao-Yuan Mo, Qiu-Yan Chen, Juan Li, Pei-Yu Huang, Yan-Fang Ye, Ying Zhang, Man-Quan Deng, Xiang Guo, Ming-Huang Hong, Ka-Jia Cao, Hai-Qiang Mai
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (8): 2451–2458.
https://doi.org/10.1158/1078-0432.CCR-10-2264
Published: 14 April 2011
View article titled, Polymorphisms in the Endothelin-1 and Endothelin A Receptor Genes and Survival in Patients with Locoregionally Advanced Nasopharyngeal Carcinoma
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Journal Articles

Antiangiogenesis Targeting Tumor Microenvironment Synergizes Glucuronide Prodrug Antitumor Activity

Ting-Yi Juan, Steve R. Roffler, Hsien-San Hou, Shih-Ming Huang, Kai-Chuan Chen, Yu-Lin Leu, Zeljko M. Prijovich, Cheng-Ping Yu, Chang-Chieh Wu, Guang-Huan Sun, Tai-Lung Cha
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (14): 4600–4611.
https://doi.org/10.1158/1078-0432.CCR-09-0090
Published: 15 July 2009
View article titled, Antiangiogenesis Targeting Tumor Microenvironment Synergizes Glucuronide Prodrug Antitumor Activity
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Journal Articles

Dual Degradation of Aurora A and B Kinases by the Histone Deacetylase Inhibitor LBH589 Induces G2-M Arrest and Apoptosis of Renal Cancer Cells

Tai-Lung Cha, Mei-Jen Chuang, Sheng-Tang Wu, Guang-Huan Sun, Sun-Yran Chang, Dah-Shyong Yu, Shih-Ming Huang, Steven Kuan-Hua Huan, Tse-Chou Cheng, Tzu-Ting Chen, Pao-Luo Fan, Pei-Wen Hsiao
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (3): 840–850.
https://doi.org/10.1158/1078-0432.CCR-08-1918
Published: 02 February 2009
View article titled, Dual Degradation of Aurora A and B Kinases by the Histone Deacetylase Inhibitor LBH589 Induces G<sub>2</sub>-M Arrest and Apoptosis of Renal Cancer Cells
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Journal Articles

Differential Methylation Hybridization Array of Endometrial Cancers Reveals Two Novel Cancer-Specific Methylation Markers

Israel Zighelboim, Paul J. Goodfellow, Amy P. Schmidt, Ken C. Walls, Mary Ann Mallon, David G. Mutch, Pearlly S. Yan, Tim Hui-Ming Huang, Matthew A. Powell
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (10): 2882–2889.
https://doi.org/10.1158/1078-0432.CCR-06-2367
Published: 15 May 2007
View article titled, Differential Methylation Hybridization Array of Endometrial Cancers Reveals Two Novel Cancer-Specific Methylation Markers
Open the PDF for Differential Methylation Hybridization Array of Endometrial Cancers Reveals Two Novel Cancer-Specific Methylation Markers in another window
Includes: Supplementary data
Journal Articles

Association of GSTP1 Polymorphism and Survival for Esophageal Cancer

Jang-Ming Lee, Ming-Tsang Wu, Yung-Chie Lee, Shi-Yi Yang, Jin-Shing Chen, Hsao-Hsun Hsu, Pei-Ming Huang, Shuenn-Wen Kuo, Chun-Jean Lee, Chien-Jen Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (13): 4749–4753.
https://doi.org/10.1158/1078-0432.CCR-04-2333
Published: 06 July 2005
View article titled, Association of <em>GSTP1</em> Polymorphism and Survival for Esophageal Cancer
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Journal Articles

Methylation Microarray Analysis of Late-Stage Ovarian Carcinomas Distinguishes Progression-free Survival in Patients and Identifies Candidate Epigenetic Markers

Susan H. Wei, Chuan-Mu Chen, Gordon Strathdee, Jaturon Harnsomburana, Chi-Ren Shyu, Farahnaz Rahmatpanah, Huidong Shi, Shu-Wing Ng, Pearlly S. Yan, Kenneth P. Nephew, Robert Brown, Tim Hui-Ming Huang
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (7): 2246–2252.
Published: 01 July 2002
View article titled, Methylation Microarray Analysis of Late-Stage Ovarian Carcinomas Distinguishes Progression-free Survival in Patients and Identifies Candidate Epigenetic Markers
Open the PDF for Methylation Microarray Analysis of Late-Stage Ovarian Carcinomas Distinguishes Progression-free Survival in Patients and Identifies Candidate Epigenetic Markers in another window
Journal Articles

CpG Island Arrays: An Application toward Deciphering Epigenetic Signatures of Breast Cancer

Pearlly S. Yan, Martin R. Perry, Douglas E. Laux, Adam L. Asare, Charles W. Caldwell, Tim Hui-Ming Huang
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (4): 1432–1438.
Published: 01 April 2000
View article titled, CpG Island Arrays: An Application toward Deciphering Epigenetic Signatures of Breast Cancer
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