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Journal Articles

Famitinib with Camrelizumab and Nab-Paclitaxel for Advanced Immunomodulatory Triple-Negative Breast Cancer (FUTURE-C-Plus): An Open-Label, Single-Arm, Phase II Trial

Li Chen, Yi-Zhou Jiang, Song-Yang Wu, Jiong Wu, Gen-Hong Di, Guang-Yu Liu, Ke-Da Yu, Lei Fan, Jun-Jie Li, Yi-Feng Hou, Zhen Hu, Can-Ming Chen, Xiao-Yan Huang, A-Yong Cao, Xin Hu, Shen Zhao, Xiao-Yan Ma, Ying Xu, Xiang-Jie Sun, Wen-Jun Chai, Xiaomao Guo, Xizi Chen, Yanhui Xu, Xiao-Yu Zhu, Jian-Jun Zou, Wen-Tao Yang, Zhong-Hua Wang, Zhi-Ming Shao
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (13): 2807–2817.
https://doi.org/10.1158/1078-0432.CCR-21-4313
Published: 01 July 2022
View article titled, Famitinib with Camrelizumab and Nab-Paclitaxel for Advanced Immunomodulatory Triple-Negative Breast Cancer (FUTURE-C-Plus): An Open-Label, Single-Arm, Phase II Trial
Open the PDF for Famitinib with Camrelizumab and Nab-Paclitaxel for Advanced Immunomodulatory Triple-Negative Breast Cancer (FUTURE-C-Plus): An Open-Label, Single-Arm, Phase II Trial in another window
Includes: Supplementary data
Journal Articles

A Phase III Multicenter Randomized Clinical Trial of 60 Gy versus 50 Gy Radiation Dose in Concurrent Chemoradiotherapy for Inoperable Esophageal Squamous Cell Carcinoma

Yujin Xu, Baiqiang Dong, Weiguo Zhu, Jiancheng Li, Rong Huang, Zongwen Sun, Xinmei Yang, Liping Liu, Han He, Zhongxing Liao, Ni Guan, Yue Kong, Wanwei Wang, Jianxiang Chen, Huijuan He, Guoqin Qiu, Ming Zeng, Juan Pu, Wangyuan Hu, Yong Bao, Zhigang Liu, Jun Ma, Hao Jiang, Xianghui Du, Jin Hu, Tingting Zhuang, Jing Cai, Jin Huang, Hua Tao, Yuan Liu, Xiaodong Liang, Juying Zhou, Guangzhou Tao, Xiao Zheng, Ming Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (9): 1792–1799.
https://doi.org/10.1158/1078-0432.CCR-21-3843
Published: 02 May 2022
View article titled, A Phase III Multicenter Randomized Clinical Trial of 60 Gy versus 50 Gy Radiation Dose in Concurrent Chemoradiotherapy for Inoperable Esophageal Squamous Cell Carcinoma
Open the PDF for A Phase III Multicenter Randomized Clinical Trial of 60 Gy versus 50 Gy Radiation Dose in Concurrent Chemoradiotherapy for Inoperable Esophageal Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Activation of PI3K/AKT Pathway Is a Potential Mechanism of Treatment Resistance in Small Cell Lung Cancer

Ying Jin, Yamei Chen, Huarong Tang, Xiao Hu, Shawna M. Hubert, Qian Li, Dan Su, Haimiao Xu, Yun Fan, Xinmin Yu, Qixun Chen, Jinshi Liu, Wei Hong, Yujin Xu, Huan Deng, Dapeng Zhu, Pansong Li, Yuhua Gong, Xuefeng Xia, Carl M. Gay, Jianjun Zhang, Ming Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (3): 526–539.
https://doi.org/10.1158/1078-0432.CCR-21-1943
Published: 01 February 2022
View article titled, Activation of PI3K/AKT Pathway Is a Potential Mechanism of Treatment Resistance in Small Cell Lung Cancer
Open the PDF for Activation of PI3K/AKT Pathway Is a Potential Mechanism of Treatment Resistance in Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

The Landscape of Cell-Free HBV Integrations and Mutations in Cirrhosis and Hepatocellular Carcinoma Patients

Bo Zheng, Xiao-Long Liu, Rong Fan, Jian Bai, Hao Wen, Lu-Tao Du, Guo-Qing Jiang, Chun-Ying Wang, Xiao-Tang Fan, Yi-Nong Ye, Yun-Song Qian, Ying-Chao Wang, Gao-Jing Liu, Guo-Hong Deng, Feng Shen, He-Ping Hu, Hui Wang, Qing-Zheng Zhang, Lan-Lan Ru, Jing Zhang, Yan-Hang Gao, Jie Xia, Hua-Dong Yan, Min-Feng Liang, Yan-Long Yu, Fu-Ming Sun, Yu-Jing Gao, Jian Sun, Chun-Xiu Zhong, Yin Wang, Fei Kong, Jin-Ming Chen, Dan Zheng, Yuan Yang, Chuan-Xin Wang, Lin Wu, Jin-Lin Hou, Jing-Feng Liu, Hong-Yang Wang, Lei Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (13): 3772–3783.
https://doi.org/10.1158/1078-0432.CCR-21-0002
Published: 01 July 2021
View article titled, The Landscape of Cell-Free HBV Integrations and Mutations in Cirrhosis and Hepatocellular Carcinoma Patients
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Includes: Supplementary data
Journal Articles

Abstract PO-069: A deep learning model assists urine cytology reporting with computational estimates of the nuclear/cytoplasmic ratios of the urothelial cells based on the Paris System

Wei-Lei Yang, Chi-Bin Li, Yen-Chuan Ou, Yi-Sheng Lin, Tang-Yi Tsao, Ming-Chen Chang, Jen-Fan Hang, Tien-Jen Liu
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (5_Supplement): PO-069.
https://doi.org/10.1158/1557-3265.ADI21-PO-069
Published: 01 March 2021
View article titled, Abstract PO-069: A deep learning model assists urine cytology reporting with computational estimates of the nuclear/cytoplasmic ratios of the urothelial cells based on the Paris System
Journal Articles

Molecular Engineering of Ultrasmall Silica Nanoparticle–Drug Conjugates as Lung Cancer Therapeutics

Brian Madajewski, Feng Chen, Barney Yoo, Melik Z. Turker, Kai Ma, Li Zhang, Pei-Ming Chen, Rupa Juthani, Virginia Aragon-Sanabria, Mithat Gonen, Charles M. Rudin, Ulrich Wiesner, Michelle S. Bradbury, Cameron Brennan
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (20): 5424–5437.
https://doi.org/10.1158/1078-0432.CCR-20-0851
Published: 15 October 2020
View article titled, Molecular Engineering of Ultrasmall Silica Nanoparticle–Drug Conjugates as Lung Cancer Therapeutics
Open the PDF for Molecular Engineering of Ultrasmall Silica Nanoparticle–Drug Conjugates as Lung Cancer Therapeutics in another window
Includes: Supplementary data
Journal Articles

Submucosal Saline Injection Followed by Endoscopic Ultrasound versus Endoscopic Ultrasound Only for Distinguishing between T1a and T1b Esophageal Cancer

Long-Jun He, Chuanbo Xie, Zi-Xian Wang, Yin Li, Yi-Tai Xiao, Xiao-Yan Gao, Hong-Bo Shan, Lin-Na Luo, Li-Ming Chen, Guang-Yu Luo, Ping Yang, Shuo-Chun Zeng, Guo-Liang Xu, Jian-Jun Li
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (2): 384–390.
https://doi.org/10.1158/1078-0432.CCR-19-1722
Published: 15 January 2020
View article titled, Submucosal Saline Injection Followed by Endoscopic Ultrasound versus Endoscopic Ultrasound Only for Distinguishing between T1a and T1b Esophageal Cancer
Open the PDF for Submucosal Saline Injection Followed by Endoscopic Ultrasound versus Endoscopic Ultrasound Only for Distinguishing between T1a and T1b Esophageal Cancer in another window
Includes: Supplementary data
Journal Articles

Ultrasmall Core-Shell Silica Nanoparticles for Precision Drug Delivery in a High-Grade Malignant Brain Tumor Model

Rupa Juthani, Brian Madajewski, Barney Yoo, Li Zhang, Pei-Ming Chen, Feng Chen, Melik Z. Turker, Kai Ma, Michael Overholtzer, Valerie A. Longo, Sean Carlin, Virginia Aragon-Sanabria, Jason Huse, Mithat Gonen, Pat Zanzonico, Charles M. Rudin, Ulrich Wiesner, Michelle S. Bradbury, Cameron W. Brennan
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (1): 147–158.
https://doi.org/10.1158/1078-0432.CCR-19-1834
Published: 03 January 2020
View article titled, Ultrasmall Core-Shell Silica Nanoparticles for Precision Drug Delivery in a High-Grade Malignant Brain Tumor Model
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Includes: Multimedia, Supplementary data
Journal Articles

Myeloid-Derived Suppressor Cells as an Immune Parameter in Patients with Concurrent Sunitinib and Stereotactic Body Radiotherapy

Hui-Ming Chen, Ge Ma, Neil Gildener-Leapman, Samuel Eisenstein, Brian A. Coakley, Junko Ozao, John Mandeli, Celia Divino, Myron Schwartz, Max Sung, Robert Ferris, Johnny Kao, Lu-Hai Wang, Ping-Ying Pan, Eric C. Ko, Shu-Hsia Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (18): 4073–4085.
https://doi.org/10.1158/1078-0432.CCR-14-2742
Published: 14 September 2015
View article titled, Myeloid-Derived Suppressor Cells as an Immune Parameter in Patients with Concurrent Sunitinib and Stereotactic Body Radiotherapy
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Includes: Supplementary data
Journal Articles

Abstract PR02: Investigating the use of tyrosine kinase inhibitors in Ph-like ALL.

Kathryn G. Roberts, Yung-Li Yang, Debbie Payne-Turner, Richard C. Harvey, I-Ming Chen, Julie M. Gastier-Foster, Mignon L. Loh, Cheryl L. Willman, Stephen P. Hunger, Charles G. Mullighan
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (17_Supplement): PR02.
https://doi.org/10.1158/1557-3265.HEMMAL14-PR02
Published: 19 August 2015
View article titled, Abstract PR02: Investigating the use of tyrosine kinase inhibitors in Ph-like ALL.
Journal Articles

Abstract B04: Investigating the use of tyrosine kinase inhibitors in Ph-like ALL.

Kathryn G. Roberts, Yung-Li Yang, Debbie Payne-Turner, Richard C. Harvey, I-Ming Chen, Julie M. Gastier-Foster, Mignon L. Loh, Cheryl L. Willman, Stephen P. Hunger, Charles G. Mullighan
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (17_Supplement): B04.
https://doi.org/10.1158/1557-3265.HEMMAL14-B04
Published: 19 August 2015
View article titled, Abstract B04: Investigating the use of tyrosine kinase inhibitors in Ph-like ALL.
Journal Articles

In vitro and Clinical Studies of Gene Therapy with Recombinant Human Adenovirus-p53 Injection for Oral Leukoplakia

Yi Li, Long-Jiang Li, Song-Tao Zhang, Li-Juan Wang, Zhuang Zhang, Ning Gao, Yuan-Yuan Zhang, Qian-Ming Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (21): 6724–6731.
https://doi.org/10.1158/1078-0432.CCR-09-1296
Published: 02 November 2009
View article titled, <em>In vitro</em> and Clinical Studies of Gene Therapy with Recombinant Human Adenovirus-<em>p53</em> Injection for Oral Leukoplakia
Open the PDF for <em>In vitro</em> and Clinical Studies of Gene Therapy with Recombinant Human Adenovirus-<em>p53</em> Injection for Oral Leukoplakia in another window
Journal Articles

RRR-α-Vitamin E Succinate Potentiates the Antitumor Effect of Calcitriol in Prostate Cancer without Overt Side Effects

Yi Yin, Jing Ni, Ming Chen, Yinglu Guo, Shuyuan Yeh
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (1): 190–200.
https://doi.org/10.1158/1078-0432.CCR-08-0910
Published: 31 December 2008
View article titled, RRR-α-Vitamin E Succinate Potentiates the Antitumor Effect of Calcitriol in Prostate Cancer without Overt Side Effects
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Journal Articles

Inhibition of the Tumor Necrosis Factor-α Pathway Is Radioprotective for the Lung

Ming Zhang, Jun Qian, Xianying Xing, Feng-Ming Kong, Lujun Zhao, Ming Chen, Theodore S. Lawrence
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (6): 1868–1876.
https://doi.org/10.1158/1078-0432.CCR-07-1894
Published: 17 March 2008
View article titled, Inhibition of the Tumor Necrosis Factor-α Pathway Is Radioprotective for the Lung
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Journal Articles

The Therapeutic and Preventive Effect of RRR-α-Vitamin E Succinate on Prostate Cancer via Induction of Insulin-Like Growth Factor Binding Protein-3

Yi Yin, Jing Ni, Ming Chen, Matthew A. DiMaggio, Yinglu Guo, Shuyuan Yeh
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (7): 2271–2280.
https://doi.org/10.1158/1078-0432.CCR-06-1217
Published: 02 April 2007
View article titled, The Therapeutic and Preventive Effect of RRR-α-Vitamin E Succinate on Prostate Cancer via Induction of Insulin-Like Growth Factor Binding Protein-3
Open the PDF for The Therapeutic and Preventive Effect of RRR-α-Vitamin E Succinate on Prostate Cancer via Induction of Insulin-Like Growth Factor Binding Protein-3 in another window