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Journal Articles

First-in-Human Study of PF-06647020 (Cofetuzumab Pelidotin), an Antibody–Drug Conjugate Targeting Protein Tyrosine Kinase 7, in Advanced Solid Tumors

Michael L. Maitland, Jasgit C. Sachdev, Manish R. Sharma, Victor Moreno, Valentina Boni, Shivaani Kummar, Erica Stringer-Reasor, Nehal Lakhani, Allison R. Moreau, Dawei Xuan, Ray Li, Eric L. Powell, Amy Jackson-Fisher, Michelle Bowers, Shilpa Alekar, Xiaohua Xin, Anthony W. Tolcher, Emiliano Calvo

Clin Cancer Res (2021) 27 (16): 4511–4520.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-3757

Published: 15 August 2021

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Includes: Supplementary data

Journal Articles

Abstract PO022: Multidimensional longitudinal assessment of patients under treatment for advanced endometrial cancer: a new tool to advance research on human disease

Erik Dvergsten, Sanja Karovic, Vasiliki Thomeas-McEwing, Danielle Kimble, Pingzhen Guo, Hao Yang, Binsheng Zhao, Lawrence H. Schwartz, Michael L. Maitland

Clin Cancer Res (2021) 27 (3_Supplement): PO022.

DOI: https://doi.org/10.1158/1557-3265.ENDOMET20-PO022

Published: 01 February 2021

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Journal Articles

Enhanced Detection of Treatment Effects on Metastatic Colorectal Cancer with Volumetric CT Measurements for Tumor Burden Growth Rate Evaluation

Michael L. Maitland, Julia Wilkerson, Sanja Karovic, Binsheng Zhao, Jessica Flynn, Mengxi Zhou, Patrick Hilden, Firas S. Ahmed, Laurent Dercle, Chaya S. Moskowitz, Ying Tang, Dana E. Connors, Stacey J. Adam, Gary Kelloff, Mithat Gonen, Tito Fojo, Lawrence H. Schwartz, Geoffrey R. Oxnard

Clin Cancer Res (2020) 26 (24): 6464–6474.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-1493

Published: 15 December 2020

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Includes: Supplementary data

Journal Articles

Cancer Clinical Investigators Should Converge with Pharmacometricians

Michael L. Maitland, Roisin E. O'Cearbhaill, Jogarao Gobburu

Clin Cancer Res (2019) 25 (17): 5182–5184.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-1067

Published: 03 September 2019

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Journal Articles

Serum C-Telopeptide Collagen Crosslinks and Plasma Soluble VEGFR2 as Pharmacodynamic Biomarkers in a Trial of Sequentially Administered Sunitinib and Cilengitide

Peter H. O'Donnell, Sanja Karovic, Theodore G. Karrison, Linda Janisch, Matthew R. Levine, Pamela J. Harris, Blase N. Polite, Ezra E.W. Cohen, Gini F. Fleming, Mark J. Ratain, Michael L. Maitland

Clin Cancer Res (2015) 21 (22): 5092–5099.

DOI: https://doi.org/10.1158/1078-0432.CCR-15-0427

Published: 12 November 2015

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Includes: Supplementary data

Journal Articles

Identification of a Variant in KDR Associated with Serum VEGFR2 and Pharmacodynamics of Pazopanib

Clin Cancer Res (2015) 21 (2): 365–372.

DOI: https://doi.org/10.1158/1078-0432.CCR-14-1683

Published: 14 January 2015

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Includes: Supplementary data

Journal Articles

Stepwise development of biomarkers for angiogenic activity with standardized assays for circulating molecules in human subjects

Michael L. Maitland, Emily Kistner, Larry House, Theodore Karrison, Mark J. Ratain

Clin Cancer Res (2006) 12 (19_Supplement): B84.

Published: 15 August 2014

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Journal Articles

Evaluation of Food Effect on Pharmacokinetics of Vismodegib in Advanced Solid Tumor Patients

Manish R. Sharma, Theodore G. Karrison, Bethany Kell, Kehua Wu, Michelle Turcich, David Geary, Soonmo P. Kang, Naoko Takebe, Richard A. Graham, Michael L. Maitland, Richard L. Schilsky, Mark J. Ratain, Ezra E.W. Cohen

Clin Cancer Res (2013) 19 (11): 3059–3067.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-3829

Published: 30 May 2013

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Journal Articles

Phase I Studies of Sirolimus Alone or in Combination with Pharmacokinetic Modulators in Advanced Cancer Patients

Ezra E.W. Cohen, Kehua Wu, Christine Hartford, Masha Kocherginsky, Kimberly Napoli Eaton, Yuanyuan Zha, Anitha Nallari, Michael L. Maitland, Kammi Fox-Kay, Kristin Moshier, Larry House, Jacqueline Ramirez, Samir D. Undevia, Gini F. Fleming, Thomas F. Gajewski, Mark J. Ratain

Clin Cancer Res (2012) 18 (17): 4785–4793.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-0110

Published: 30 August 2012

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Includes: Supplementary data

Journal Articles

Resampling Phase III Data to Assess Phase II Trial Designs and Endpoints

Manish R. Sharma, Theodore G. Karrison, Yuyan Jin, Robert R. Bies, Michael L. Maitland, Walter M. Stadler, Mark J. Ratain

Clin Cancer Res (2012) 18 (8): 2309–2315.

DOI: https://doi.org/10.1158/1078-0432.CCR-11-1815

Published: 16 April 2012

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Includes: Supplementary data

Journal Articles

Two Drug Interaction Studies of Sirolimus in Combination with Sorafenib or Sunitinib in Patients with Advanced Malignancies

Tara C. Gangadhar, Ezra E.W. Cohen, Kehua Wu, Linda Janisch, David Geary, Masha Kocherginsky, Larry K. House, Jackie Ramirez, Samir D. Undevia, Michael L. Maitland, Gini F. Fleming, Mark J. Ratain

Clin Cancer Res (2011) 17 (7): 1956–1963.

DOI: https://doi.org/10.1158/1078-0432.CCR-10-2061

Published: 31 March 2011

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Journal Articles

Analysis of the Yield of Phase II Combination Therapy Trials in Medical Oncology

Michael L. Maitland, Christine Hudoba, Kelly L. Snider, Mark J. Ratain

Clin Cancer Res (2010) 16 (21): 5296–5302.

DOI: https://doi.org/10.1158/1078-0432.CCR-10-0669

Published: 31 October 2010

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Journal Articles

Volumes to Learn: Advancing Therapeutics with Innovative Computed Tomography Image Data Analysis

Michael L. Maitland

Clin Cancer Res (2010) 16 (18): 4493–4495.

DOI: https://doi.org/10.1158/1078-0432.CCR-10-1548

Published: 14 September 2010

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Includes: Supplementary data

Journal Articles

Ambulatory Monitoring Detects Sorafenib-Induced Blood Pressure Elevations on the First Day of Treatment

Michael L. Maitland, Kristen E. Kasza, Theodore Karrison, Kristin Moshier, Laura Sit, Henry R. Black, Samir D. Undevia, Walter M. Stadler, William J. Elliott, Mark J. Ratain

Clin Cancer Res (2009) 15 (19): 6250–6257.

DOI: https://doi.org/10.1158/1078-0432.CCR-09-0058

Published: 30 September 2009

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Includes: Supplementary data

NARROW

First-in-Human Study of PF-06647020 (Cofetuzumab Pelidotin), an Antibody–Drug Conjugate Targeting Protein Tyrosine Kinase 7, in Advanced Solid Tumors

Abstract PO022: Multidimensional longitudinal assessment of patients under treatment for advanced endometrial cancer: a new tool to advance research on human disease

Enhanced Detection of Treatment Effects on Metastatic Colorectal Cancer with Volumetric CT Measurements for Tumor Burden Growth Rate Evaluation

Cancer Clinical Investigators Should Converge with Pharmacometricians

Serum C-Telopeptide Collagen Crosslinks and Plasma Soluble VEGFR2 as Pharmacodynamic Biomarkers in a Trial of Sequentially Administered Sunitinib and Cilengitide

Identification of a Variant in KDR Associated with Serum VEGFR2 and Pharmacodynamics of Pazopanib

Stepwise development of biomarkers for angiogenic activity with standardized assays for circulating molecules in human subjects

Evaluation of Food Effect on Pharmacokinetics of Vismodegib in Advanced Solid Tumor Patients

Phase I Studies of Sirolimus Alone or in Combination with Pharmacokinetic Modulators in Advanced Cancer Patients

Resampling Phase III Data to Assess Phase II Trial Designs and Endpoints

Two Drug Interaction Studies of Sirolimus in Combination with Sorafenib or Sunitinib in Patients with Advanced Malignancies

Analysis of the Yield of Phase II Combination Therapy Trials in Medical Oncology

Volumes to Learn: Advancing Therapeutics with Innovative Computed Tomography Image Data Analysis

Ambulatory Monitoring Detects Sorafenib-Induced Blood Pressure Elevations on the First Day of Treatment

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