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Journal Articles

The Role of the TP53 Pathway in Predicting Response to Neoadjuvant Therapy in Esophageal Adenocarcinoma

Smita Sihag, Samuel C. Nussenzweig, Henry S. Walch, Meier Hsu, Kay See Tan, Sergio De La Torre, Yelena Y. Janjigian, Steven B. Maron, Geoffrey Y. Ku, Laura H. Tang, Pari M. Shah, Abraham Wu, David R. Jones, David B. Solit, Nikolaus Schultz, Karuna Ganesh, Michael F. Berger, Daniela Molena

Clin Cancer Res OF1–OF10.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-4016

Published: 03 May 2022

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Includes: Supplementary data

Journal Articles

Phase Ib Trial of the Combination of Imatinib and Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumors

Clin Cancer Res (2022) 28 (8): 1507–1517.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-3909

Published: 14 April 2022

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Includes: Supplementary data

Journal Articles

Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors

Clin Cancer Res (2022) 28 (2): 318–326.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-2577

Published: 19 January 2022

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Includes: Supplementary data

Journal Articles

Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways

Clin Cancer Res (2021) 27 (12): 3491–3498.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-4707

Published: 15 June 2021

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Includes: Supplementary data

Journal Articles

Targeting Germline- and Tumor-Associated Nucleotide Excision Repair Defects in Cancer

Clin Cancer Res (2021) 27 (7): 1997–2010.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-3322

Published: 01 April 2021

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Includes: Supplementary data

Journal Articles

Characterization and Clinical Outcomes of DNA Mismatch Repair–deficient Small Bowel Adenocarcinoma

Clin Cancer Res (2021) 27 (5): 1429–1437.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-2892

Published: 01 March 2021

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Includes: Supplementary data

Journal Articles

Abstract A14: Next-generation sequencing of Bacille Calmette-Guerin (BCG)-unresponsive tumors identifies actionable alterations for potential targeted therapy in non-muscle invasive bladder cancer

Aleksandra Walasek, Nima Almassi, Victor McPherson, Shawn Dason, Nicole Benfante, Tanya Klein, Michael F. Berger, Nikolaus Schultz, Guido Dalbagni, Dean F. Bajorin, Jonathan E. Rosenberg, Hikmat Al-Ahmadie, Bernard H. Bochner, David B. Solit, Gopakumar Iyer, Eugene J. Pietzak

Clin Cancer Res (2020) 26 (15_Supplement): A14.

DOI: https://doi.org/10.1158/1557-3265.BLADDER19-A14

Published: 03 August 2020

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Journal Articles

Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection

Clin Cancer Res (2020) 26 (13): 3239–3247.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-0418

Published: 01 July 2020

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Includes: Supplementary data

Journal Articles

Abstract PR07: MSI detection in plasma cfDNA: MSI as a marker of disease burden

Preethi Srinivasan, Alicia Latham, Zalak Patel, John Ziegler, Maysun Hasan, Juber A. Patel, Ian Johnson, Ronak Shah, Fanli Meng, Xiaohong Jing, Grittney Tam, Rose Brannon, Andrea Cercek, Ahmet Zehir, Brian Houck-Loomis, Dana Tsui, Zsofia Stadler, Michael F. Berger

Clin Cancer Res (2020) 26 (11_Supplement): PR07.

DOI: https://doi.org/10.1158/1557-3265.LiqBiop20-PR07

Published: 01 June 2020

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Journal Articles

Abstract A25: Cell-free DNA for noninvasive molecular profiling and response monitoring in pediatric cancers

Prachi Kothari, Julie Yang, Caitlin Stewart, Erika Gedvilaite, Dennis Stephens, Michael F. Berger, Michael V. Ortiz, Neerav Shukla, Emily Slotkin, Shakeel Modak, Dana W. Y. Tsui

Clin Cancer Res (2020) 26 (11_Supplement): A25.

DOI: https://doi.org/10.1158/1557-3265.LiqBiop20-A25

Published: 01 June 2020

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Journal Articles

Coaltered Ras/B-raf and TP53 Is Associated with Extremes of Survivorship and Distinct Patterns of Metastasis in Patients with Metastatic Colorectal Cancer

Clin Cancer Res (2020) 26 (5): 1077–1085.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-2390

Published: 02 March 2020

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Includes: Supplementary data

Journal Articles

Genomic Profiling Identifies Association of IDH1/IDH2 Mutation with Longer Relapse-Free and Metastasis-Free Survival in High-Grade Chondrosarcoma

Guo Gord Zhu, Khedoudja Nafa, Narasimhan Agaram, Ahmet Zehir, Ryma Benayed, Justyna Sadowska, Laetitia Borsu, Ciara Kelly, William D. Tap, Nicola Fabbri, Edward Athanasian, Patrick J. Boland, John H. Healey, Michael F. Berger, Marc Ladanyi, Meera Hameed

Clin Cancer Res (2020) 26 (2): 419–427.

DOI: https://doi.org/10.1158/1078-0432.CCR-18-4212

Published: 15 January 2020

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Includes: Supplementary data

Journal Articles

Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma

Clin Cancer Res (2019) 25 (24): 7475–7484.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-1651

Published: 13 December 2019

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Includes: Supplementary data

Journal Articles

Clinical and Molecular Predictors of Response to Immune Checkpoint Inhibitors in Patients with Advanced Esophagogastric Cancer

Megan Greally, Joanne F. Chou, Walid K. Chatila, Matthew Margolis, Marinela Capanu, Jaclyn F. Hechtman, Yaelle Tuvy, Ritika Kundra, Foysal Daian, Marc Ladanyi, David P. Kelsen, David H. Ilson, Michael F. Berger, Laura H. Tang, David B. Solit, Luis A. Diaz, Jr, Nikolaus Schultz, Yelena Y. Janjigian, Geoffrey Y. Ku

Clin Cancer Res (2019) 25 (20): 6160–6169.

DOI: https://doi.org/10.1158/1078-0432.CCR-18-3603

Published: 15 October 2019

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Includes: Supplementary data

Journal Articles

Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas

Clin Cancer Res (2019) 25 (18): 5537–5547.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-0032

Published: 13 September 2019

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Includes: Supplementary data

Journal Articles

High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden

Ryma Benayed, Michael Offin, Kerry Mullaney, Purvil Sukhadia, Kelly Rios, Patrice Desmeules, Ryan Ptashkin, Helen Won, Jason Chang, Darragh Halpenny, Alison M. Schram, Charles M. Rudin, David M. Hyman, Maria E. Arcila, Michael F. Berger, Ahmet Zehir, Mark G. Kris, Alexander Drilon, Marc Ladanyi

Clin Cancer Res (2019) 25 (15): 4712–4722.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-0225

Published: 01 August 2019

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Includes: Supplementary data

Journal Articles

Efficacy of Combined VEGFR1-3, PDGFα/β, and FGFR1-3 Blockade Using Nintedanib for Esophagogastric Cancer

Clin Cancer Res (2019) 25 (13): 3811–3817.

DOI: https://doi.org/10.1158/1078-0432.CCR-18-3789

Published: 01 July 2019

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Includes: Supplementary data

Journal Articles

Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next-Generation Sequencing for Matching Patients to Targeted and Immune Therapies

Clin Cancer Res (2019) 25 (7): 2116–2126.

DOI: https://doi.org/10.1158/1078-0432.CCR-18-2293

Published: 01 April 2019

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Includes: Supplementary data

Journal Articles

Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma

Clin Cancer Res (2019) 25 (3): 967–976.

DOI: https://doi.org/10.1158/1078-0432.CCR-18-2039

Published: 01 February 2019

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Includes: Supplementary data

Journal Articles

Clinical Utility of Prospective Molecular Characterization in Advanced Endometrial Cancer

Clin Cancer Res (2018) 24 (23): 5939–5947.

DOI: https://doi.org/10.1158/1078-0432.CCR-18-0412

Published: 03 December 2018

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Includes: Supplementary data

NARROW

The Role of the TP53 Pathway in Predicting Response to Neoadjuvant Therapy in Esophageal Adenocarcinoma

Phase Ib Trial of the Combination of Imatinib and Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumors

Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors

Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways

Targeting Germline- and Tumor-Associated Nucleotide Excision Repair Defects in Cancer

Characterization and Clinical Outcomes of DNA Mismatch Repair–deficient Small Bowel Adenocarcinoma

Abstract A14: Next-generation sequencing of Bacille Calmette-Guerin (BCG)-unresponsive tumors identifies actionable alterations for potential targeted therapy in non-muscle invasive bladder cancer

Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection

Abstract PR07: MSI detection in plasma cfDNA: MSI as a marker of disease burden

Abstract A25: Cell-free DNA for noninvasive molecular profiling and response monitoring in pediatric cancers

Coaltered Ras/B-raf and TP53 Is Associated with Extremes of Survivorship and Distinct Patterns of Metastasis in Patients with Metastatic Colorectal Cancer

Genomic Profiling Identifies Association of IDH1/IDH2 Mutation with Longer Relapse-Free and Metastasis-Free Survival in High-Grade Chondrosarcoma

Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma

Clinical and Molecular Predictors of Response to Immune Checkpoint Inhibitors in Patients with Advanced Esophagogastric Cancer

Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas

High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden

Efficacy of Combined VEGFR1-3, PDGFα/β, and FGFR1-3 Blockade Using Nintedanib for Esophagogastric Cancer

Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next-Generation Sequencing for Matching Patients to Targeted and Immune Therapies

Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma

Clinical Utility of Prospective Molecular Characterization in Advanced Endometrial Cancer

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