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Michael A. Carducci
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Journal Articles

Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2, or ATM Alterations Identified by Testing Circulating Tumor DNA

Nobuaki Matsubara, Johann de Bono, David Olmos, Giuseppe Procopio, Satoru Kawakami, Yüksel Ürün, Robbert van Alphen, Aude Flechon, Michael A. Carducci, Young Deuk Choi, Sebastien J. Hotte, Ernesto Korbenfeld, Gero Kramer, Neeraj Agarwal, Kim N. Chi, Simon Dearden, Christopher Gresty, Jinyu Kang, Christian Poehlein, Elizabeth A. Harrington, Maha Hussain
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (1): 92–99.
https://doi.org/10.1158/1078-0432.CCR-21-3577
Published: 04 January 2023
View article titled, Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and <em>BRCA1, BRCA2</em>, or <em>ATM</em> Alterations Identified by Testing Circulating Tumor DNA
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Includes: Supplementary data
Journal Articles

Phase Ib Study of the BET Inhibitor GS-5829 as Monotherapy and Combined with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer

Rahul Aggarwal, Alexander N. Starodub, Brian D. Koh, Guan Xing, Andrew J. Armstrong, Michael A. Carducci
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18): 3979–3989.
https://doi.org/10.1158/1078-0432.CCR-22-0175
Published: 15 September 2022
View article titled, Phase Ib Study of the BET Inhibitor GS-5829 as Monotherapy and Combined with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Phase I and Pharmacokinetic Study of Romidepsin in Patients with Cancer and Hepatic Dysfunction: A National Cancer Institute Organ Dysfunction Working Group Study

Roisin M. Connolly, Eric Laille, Ulka Vaishampayan, Vincent Chung, Karen Kelly, Afshin Dowlati, Olatunji B. Alese, R. Donald Harvey, Paul Haluska, Lillian L. Siu, Shivaani Kummar, Richard Piekarz, S. Percy Ivy, Nicole M. Anders, Melinda Downs, Ashley O'Connor, Angela Scardina, Jacqueline Saunders, Gary L. Rosner, Michael A. Carducci, Michelle A. Rudek
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (20): 5329–5337.
https://doi.org/10.1158/1078-0432.CCR-20-1412
Published: 15 October 2020
View article titled, Phase I and Pharmacokinetic Study of Romidepsin in Patients with Cancer and Hepatic Dysfunction: A National Cancer Institute Organ Dysfunction Working Group Study
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Journal Articles

Muscadine Grape Skin Extract (MPX) in Men with Biochemically Recurrent Prostate Cancer: A Randomized, Multicenter, Placebo-Controlled Clinical Trial

Channing J. Paller, Xian C. Zhou, Elisabeth I. Heath, Mary-Ellen Taplin, Tina Mayer, Mark N. Stein, Glenn J. Bubley, Roberto Pili, Tamaro Hudson, Radhika Kakarla, Muneer M. Abbas, Nicole M. Anders, Donna Dowling, Serina King, Ashley B. Bruns, William D. Wagner, Charles G. Drake, Emmanuel S. Antonarakis, Mario A. Eisenberger, Samuel R. Denmeade, Michelle A. Rudek, Gary L. Rosner, Michael A. Carducci
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (2): 306–315.
https://doi.org/10.1158/1078-0432.CCR-17-1100
Published: 15 January 2018
View article titled, Muscadine Grape Skin Extract (MPX) in Men with Biochemically Recurrent Prostate Cancer: A Randomized, Multicenter, Placebo-Controlled Clinical Trial
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Includes: Supplementary data
Journal Articles

Immunomodulation by Entinostat in Renal Cell Carcinoma Patients Receiving High-Dose Interleukin 2: A Multicenter, Single-Arm, Phase I/II Trial (NCI-CTEP#7870)

Roberto Pili, David I. Quinn, Hans J. Hammers, Paul Monk, Saby George, Tanya B. Dorff, Thomas Olencki, Li Shen, Ashley Orillion, Dominick Lamonica, Roberto S. Fragomeni, Zsolt Szabo, Alan Hutson, Adrienne Groman, Susan M. Perkins, Richard Piekarz, Michael A. Carducci
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (23): 7199–7208.
https://doi.org/10.1158/1078-0432.CCR-17-1178
Published: 30 November 2017
View article titled, Immunomodulation by Entinostat in Renal Cell Carcinoma Patients Receiving High-Dose Interleukin 2: A Multicenter, Single-Arm, Phase I/II Trial (NCI-CTEP#7870)
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Includes: Supplementary data
Journal Articles

Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy

Daniel L. Hertz, Kouros Owzar, Sherrie Lessans, Claudia Wing, Chen Jiang, William Kevin Kelly, Jai Patel, Susan Halabi, Yoichi Furukawa, Heather E. Wheeler, Alexander B. Sibley, Cameron Lassiter, Lois Weisman, Dorothy Watson, Stefanie D. Krens, Flora Mulkey, Cynthia L. Renn, Eric J. Small, Phillip G. Febbo, Ivo Shterev, Deanna L. Kroetz, Paula N. Friedman, John F. Mahoney, Michael A. Carducci, Michael J. Kelley, Yusuke Nakamura, Michiaki Kubo, Susan G. Dorsey, M. Eileen Dolan, Michael J. Morris, Mark J. Ratain, Howard L. McLeod
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (19): 4890–4900.
https://doi.org/10.1158/1078-0432.CCR-15-2823
Published: 02 October 2016
View article titled, Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a <em>VAC14</em> Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy
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Includes: Supplementary data
Journal Articles

First-in-Human Dose Study of the Novel Transforming Growth Factor-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Patients with Advanced Cancer and Glioma

Jordi Rodon, Michael A. Carducci, Juan M Sepulveda-Sánchez, Analia Azaro, Emiliano Calvo, Joan Seoane, Irene Braña, Elisabet Sicart, Ivelina Gueorguieva, Ann L. Cleverly, N. Sokalingum Pillay, Durisala Desaiah, Shawn T. Estrem, Luis Paz-Ares, Matthias Holdhoff, Jaishri Blakeley, Michael M. Lahn, Jose Baselga
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (3): 553–560.
https://doi.org/10.1158/1078-0432.CCR-14-1380
Published: 01 February 2015
View article titled, First-in-Human Dose Study of the Novel Transforming Growth Factor-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Patients with Advanced Cancer and Glioma
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Includes: Supplementary data
Journal Articles

Tales of How Great Drugs Were Brought Down by a Flawed Rationale—Letter

Michel D. Wissing, Michael A. Carducci, Hans Gelderblom, Paul J. van Diest
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (5): 1303.
https://doi.org/10.1158/1078-0432.CCR-12-2695
Published: 03 March 2013
View article titled, Tales of How Great Drugs Were Brought Down by a Flawed Rationale—Letter
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Journal Articles

Phase I Dose-Escalation Study of the Novel Antiandrogen BMS-641988 in Patients with Castration-Resistant Prostate Cancer

Dana Rathkopf, Glenn Liu, Michael A. Carducci, Mario A. Eisenberger, Aseem Anand, Michael J. Morris, Susan F. Slovin, Yasutsuna Sasaki, Shunji Takahashi, Seiichiro Ozono, Nga Kit Eliza Fung, Shinta Cheng, Jinping Gan, Marco Gottardis, Mary T. Obermeier, Jyotsna Reddy, Steven Zhang, Blisse J. Vakkalagadda, Leila Alland, George Wilding, Howard I. Scher
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (4): 880–887.
https://doi.org/10.1158/1078-0432.CCR-10-2955
Published: 15 February 2011
View article titled, Phase I Dose-Escalation Study of the Novel Antiandrogen BMS-641988 in Patients with Castration-Resistant Prostate Cancer
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Journal Articles

A Pharmacodynamic Study of Rapamycin in Men with Intermediate- to High-Risk Localized Prostate Cancer

Andrew J. Armstrong, George J. Netto, Michelle A. Rudek, Susan Halabi, David P. Wood, Patricia A. Creel, Kelly Mundy, S. Lindsay Davis, Ting Wang, Roula Albadine, Luciana Schultz, Alan W. Partin, Antonio Jimeno, Helen Fedor, Phillip G. Febbo, Daniel J. George, Robin Gurganus, Angelo M. De Marzo, Michael A. Carducci
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (11): 3057–3066.
https://doi.org/10.1158/1078-0432.CCR-10-0124
Published: 31 May 2010
View article titled, A Pharmacodynamic Study of Rapamycin in Men with Intermediate- to High-Risk Localized Prostate Cancer
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Includes: Supplementary data
Journal Articles

A Phase I Dose-Finding Study of 5-Azacytidine in Combination with Sodium Phenylbutyrate in Patients with Refractory Solid Tumors

Jianqing Lin, Jill Gilbert, Michelle A. Rudek, James A. Zwiebel, Steve Gore, Anchalee Jiemjit, Ming Zhao, Sharyn D. Baker, Richard F. Ambinder, James G. Herman, Ross C. Donehower, Michael A. Carducci
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (19): 6241–6249.
https://doi.org/10.1158/1078-0432.CCR-09-0567
Published: 30 September 2009
View article titled, A Phase I Dose-Finding Study of 5-Azacytidine in Combination with Sodium Phenylbutyrate in Patients with Refractory Solid Tumors
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Includes: Supplementary data
Journal Articles

A Phase II Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Hormone-Refractory Metastatic Prostate Cancer

Elisabeth I. Heath, David W. Hillman, Ulka Vaishampayan, Shijie Sheng, Fazlul Sarkar, Felicity Harper, Melvin Gaskins, Henry C. Pitot, Winston Tan, S. Percy Ivy, Roberto Pili, Michael A. Carducci, Charles Erlichman, Glenn Liu
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (23): 7940–7946.
https://doi.org/10.1158/1078-0432.CCR-08-0221
Published: 01 December 2008
View article titled, A Phase II Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Hormone-Refractory Metastatic Prostate Cancer
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Journal Articles

A Multiple-Loop, Double-Cube Microarray Design Applied to Prostate Cancer Cell Lines with Variable Sensitivity to Histone Deacetylase Inhibitors

Madeleine S.Q. Kortenhorst, Marianna Zahurak, Shabana Shabbeer, Sushant Kachhap, Nathan Galloway, Giovanni Parmigiani, Henk M.W. Verheul, Michael A. Carducci
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (21): 6886–6894.
https://doi.org/10.1158/1078-0432.CCR-08-0119
Published: 03 November 2008
View article titled, A Multiple-Loop, Double-Cube Microarray Design Applied to Prostate Cancer Cell Lines with Variable Sensitivity to Histone Deacetylase Inhibitors
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Journal Articles

Evaluation of the Pharmacodynamic Effects of MGCD0103 from Preclinical Models to Human Using a Novel HDAC Enzyme Assay

Claire Bonfils, Ann Kalita, Marja Dubay, Lillian L. Siu, Michael A. Carducci, Gregory Reid, Robert E. Martell, Jeffrey M. Besterman, Zuomei Li
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (11): 3441–3449.
https://doi.org/10.1158/1078-0432.CCR-07-4427
Published: 02 June 2008
View article titled, Evaluation of the Pharmacodynamic Effects of MGCD0103 from Preclinical Models to Human Using a Novel HDAC Enzyme Assay
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Journal Articles

Targeting Bone Metastasis in Prostate Cancer with Endothelin Receptor Antagonists

Michael A. Carducci, Antonio Jimeno
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (20): 6296s–6300s.
https://doi.org/10.1158/1078-0432.CCR-06-0929
Published: 24 October 2006
View article titled, Targeting Bone Metastasis in Prostate Cancer with Endothelin Receptor Antagonists
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Journal Articles

Advances in Treating Metastatic Bone Cancer: Summary Statement for the First Cambridge Conference

Allan Lipton, James R. Berenson, Jean-Jacques Body, Brendan F. Boyce, Oyvind S. Bruland, Michael A. Carducci, Charles S. Cleeland, Denis R. Clohisy, Robert E. Coleman, Richard J. Cook, Theresa A. Guise, Roger N. Pearse, Trevor J. Powles, Michael J. Rogers, G. David Roodman, Matthew R. Smith, Larry J. Suva, Robert L. Vessella, Katherine N. Weilbaecher, Laura King
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (20): 6209s–6212s.
https://doi.org/10.1158/1078-0432.CCR-06-1213
Published: 24 October 2006
View article titled, Advances in Treating Metastatic Bone Cancer: Summary Statement for the First Cambridge Conference
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Journal Articles

Phase I/II Trial of an Allogeneic Cellular Immunotherapy in Hormone-Naïve Prostate Cancer

Jonathan W. Simons, Michael A. Carducci, Bahar Mikhak, Michael Lim, Barbara Biedrzycki, Flavia Borellini, Shirley M. Clift, Kristen M. Hege, Dale G. Ando, Steven Piantadosi, Richard Mulligan, William G. Nelson
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (11): 3394–3401.
https://doi.org/10.1158/1078-0432.CCR-06-0145
Published: 01 June 2006
View article titled, Phase I/II Trial of an Allogeneic Cellular Immunotherapy in Hormone-Naïve Prostate Cancer
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Journal Articles

Phase I trial of bortezomib in combination with docetaxel in patients with advanced solid tumors.

Wells A Messersmith, Sharyn D Baker, Lance Lassiter, Rana A Sullivan, Kimberly Dinh, Virna I Almuete, John J Wright, Ross C Donehower, Michael A Carducci, Deborah K Armstrong
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (4): 1270–1275.
https://doi.org/10.1158/1078-0432.CCR-05-1942
Published: 17 February 2006
View article titled, Phase I trial of bortezomib in combination with docetaxel in patients with advanced solid tumors.
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Journal Articles

Marimastat in the Treatment of Patients with Biochemically Relapsed Prostate Cancer: A Prospective Randomized, Double-Blind, Phase I/II Trial

Eli Rosenbaum, Marianna Zahurak, Victoria Sinibaldi, Michael A. Carducci, Roberto Pili, Menachem Laufer, Theodore L. DeWeese, Mario A. Eisenberger
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (12): 4437–4443.
https://doi.org/10.1158/1078-0432.CCR-04-2252
Published: 15 June 2005
View article titled, Marimastat in the Treatment of Patients with Biochemically Relapsed Prostate Cancer: A Prospective Randomized, Double-Blind, Phase I/II Trial
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Journal Articles

A Phase I and Pharmacokinetic Study of Short Infusions of UCN-01 in Patients with Refractory Solid Tumors

E. Claire Dees, Sharyn D. Baker, Seamus O'Reilly, Michelle A. Rudek, Susan B. Davidson, Cheryl Aylesworth, Kathy Elza-Brown, Michael A. Carducci, Ross C. Donehower
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (2): 664–671.
https://doi.org/10.1158/1078-0432.664.11.2
Published: 08 February 2005
View article titled, A Phase I and Pharmacokinetic Study of Short Infusions of UCN-01 in Patients with Refractory Solid Tumors
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