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Journal Articles

COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms

Clin Cancer Res (2019) 25 (18): 5650–5662.

https://doi.org/10.1158/1078-0432.CCR-19-0096

Published: 13 September 2019

View article titled, COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms

Includes: Multimedia, Supplementary data

Journal Articles

High-Risk TP53 Mutations Are Associated with Extranodal Extension in Oral Cavity Squamous Cell Carcinoma

Vlad C. Sandulache, Chieko Michikawa, Pranav Kataria, Frederico O. Gleber-Netto, Diana Bell, Sanchit Trivedi, Xiayu Rao, Jing Wang, Mei Zhao, Samar Jasser, Jeffrey N. Myers, Curtis R. Pickering

Clin Cancer Res (2018) 24 (7): 1727–1733.

https://doi.org/10.1158/1078-0432.CCR-17-0721

Published: 02 April 2018

View article titled, High-Risk TP53 Mutations Are Associated with Extranodal Extension in Oral Cavity Squamous Cell Carcinoma

Includes: Supplementary data

Journal Articles

Abstract 73: Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cell by targeting forkhead transcription factors FOXO3a and FOXM1

Noriaki Tanaka, Mei Zhao, Jiexin Zhang, Jing Wang, Ge Zhou, Jeffrey N. Myers

Clin Cancer Res (2017) 23 (23_Supplement): 73.

https://doi.org/10.1158/1557-3265.AACRAHNS17-73

Published: 30 November 2017

View article titled, Abstract 73: Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cell by targeting forkhead transcription factors FOXO3a and FOXM1

Journal Articles

Abstract 44: Synergistic antitumor activity of olaparib combined with AZD1775 in head and neck squamous cell carcinoma

Hideaki Takahashi, Antje Lindemann, Ameeta A. Patel, Weiwei Liu, Noriaki Tanaka, Lin Tang, Mei Zhao, Walter N. Hittelman, Jeffrey N. Myers, Abdullah A. Osman

Clin Cancer Res (2017) 23 (23_Supplement): 44.

https://doi.org/10.1158/1557-3265.AACRAHNS17-44

Published: 30 November 2017

View article titled, Abstract 44: Synergistic antitumor activity of olaparib combined with AZD1775 in head and neck squamous cell carcinoma

Journal Articles

Wee-1 Kinase Inhibition Sensitizes High-Risk HPV⁺ HNSCC to Apoptosis Accompanied by Downregulation of MCl-1 and XIAP Antiapoptotic Proteins

Noriaki Tanaka, Ameeta A. Patel, Jiping Wang, Mitchell J. Frederick, Nene N. Kalu, Mei Zhao, Alison L. Fitzgerald, Tong-xin Xie, Natalie L. Silver, Carlos Caulin, Ge Zhou, Heath D. Skinner, Faye M. Johnson, Jeffrey N. Myers, Abdullah A. Osman

Clin Cancer Res (2015) 21 (21): 4831–4844.

https://doi.org/10.1158/1078-0432.CCR-15-0279

Published: 01 November 2015

View article titled, Wee-1 Kinase Inhibition Sensitizes High-Risk HPV+ HNSCC to Apoptosis Accompanied by Downregulation of MCl-1 and XIAP Antiapoptotic Proteins

Includes: Supplementary data

Journal Articles

Squamous Cell Carcinoma of the Oral Tongue in Young Non-Smokers Is Genomically Similar to Tumors in Older Smokers

Curtis R. Pickering, Jiexin Zhang, David M. Neskey, Mei Zhao, Samar A. Jasser, Jiping Wang, Alexandra Ward, C. Jillian Tsai, Marcus V. Ortega Alves, Jane H. Zhou, Jennifer Drummond, Adel K. El-Naggar, Richard Gibbs, John N. Weinstein, David A. Wheeler, Jing Wang, Mitchell J. Frederick, Jeffrey N. Myers

Clin Cancer Res (2014) 20 (14): 3842–3848.

https://doi.org/10.1158/1078-0432.CCR-14-0565

Published: 14 July 2014

View article titled, Squamous Cell Carcinoma of the Oral Tongue in Young Non-Smokers Is Genomically Similar to Tumors in Older Smokers

Includes: Supplementary data

Journal Articles

Establishment and Characterization of Novel Cell Lines from Sinonasal Undifferentiated Carcinoma

Yoko Takahashi, Michael E. Kupferman, Diana Bell, Tilahun Jiffar, June Goo Lee, Tong-Xin Xie, Ning-Wei Li, Mei Zhao, Mitchell J. Frederick, Alexander Gelbard, Jeffrey N. Myers, Ehab Y. Hanna

Clin Cancer Res (2012) 18 (22): 6178–6187.

https://doi.org/10.1158/1078-0432.CCR-12-1876

Published: 14 November 2012

View article titled, Establishment and Characterization of Novel Cell Lines from Sinonasal Undifferentiated Carcinoma

Includes: Supplementary data

Journal Articles

Assembly and Initial Characterization of a Panel of 85 Genomically Validated Cell Lines from Diverse Head and Neck Tumor Sites

Mei Zhao, Daisuke Sano, Curtis R. Pickering, Samar A. Jasser, Ying C. Henderson, Gary L. Clayman, Erich M. Sturgis, Thomas J. Ow, Reuben Lotan, Thomas E. Carey, Peter G. Sacks, Jennifer R. Grandis, David Sidransky, Nils Erik Heldin, Jeffrey N. Myers

Clin Cancer Res (2011) 17 (23): 7248–7264.

https://doi.org/10.1158/1078-0432.CCR-11-0690

Published: 30 November 2011

View article titled, Assembly and Initial Characterization of a Panel of 85 Genomically Validated Cell Lines from Diverse Head and Neck Tumor Sites

Includes: Supplementary data

Journal Articles

Disruptive TP53 Mutation Is Associated with Aggressive Disease Characteristics in an Orthotopic Murine Model of Oral Tongue Cancer

Daisuke Sano, Tong-Xin Xie, Thomas J. Ow, Mei Zhao, Curtis R. Pickering, Ge Zhou, Vlad C. Sandulache, David A. Wheeler, Richard A. Gibbs, Carlos Caulin, Jeffrey N. Myers

Clin Cancer Res (2011) 17 (21): 6658–6670.

https://doi.org/10.1158/1078-0432.CCR-11-0046

Published: 31 October 2011

View article titled, Disruptive TP53 Mutation Is Associated with Aggressive Disease Characteristics in an Orthotopic Murine Model of Oral Tongue Cancer

Includes: Supplementary data

Journal Articles

Targeted Therapy of VEGFR2 and EGFR Significantly Inhibits Growth of Anaplastic Thyroid Cancer in an Orthotopic Murine Model

Maria K. Gule, Yunyun Chen, Daisuke Sano, Mitchell J. Frederick, Ge Zhou, Mei Zhao, Zvonimir L. Milas, Chad E. Galer, Ying C. Henderson, Samar A. Jasser, David L. Schwartz, James A. Bankson, Jeffrey N. Myers, Stephen Y. Lai

Clin Cancer Res (2011) 17 (8): 2281–2291.

https://doi.org/10.1158/1078-0432.CCR-10-2762

Published: 14 April 2011

View article titled, Targeted Therapy of VEGFR2 and EGFR Significantly Inhibits Growth of Anaplastic Thyroid Cancer in an Orthotopic Murine Model

Includes: Supplementary data

Journal Articles

Vandetanib Restores Head and Neck Squamous Cell Carcinoma Cells' Sensitivity to Cisplatin and Radiation In Vivo and In Vitro

Daisuke Sano, Fumihiko Matsumoto, David R. Valdecanas, Mei Zhao, David P. Molkentine, Yoko Takahashi, Ehab Y. Hanna, Vali Papadimitrakopoulou, John Heymach, Luka Milas, Jeffrey N. Myers

Clin Cancer Res (2011) 17 (7): 1815–1827.

https://doi.org/10.1158/1078-0432.CCR-10-2120

Published: 31 March 2011

View article titled, Vandetanib Restores Head and Neck Squamous Cell Carcinoma Cells' Sensitivity to Cisplatin and Radiation In Vivo and In Vitro

Includes: Supplementary data

Journal Articles

Vandetanib Inhibits Growth of Adenoid Cystic Carcinoma in an Orthotopic Nude Mouse Model

Sungweon Choi, Daisuke Sano, Melvina Cheung, Mei Zhao, Samar A. Jasser, Anderson J. Ryan, Li Mao, Wan-Tao Chen, Adel K. El-Naggar, Jeffrey N. Myers

Clin Cancer Res (2008) 14 (16): 5081–5089.

https://doi.org/10.1158/1078-0432.CCR-08-0245

Published: 12 August 2008

View article titled, Vandetanib Inhibits Growth of Adenoid Cystic Carcinoma in an Orthotopic Nude Mouse Model

Journal Articles

The Tyrosine Kinase Inhibitor, AZD2171, Inhibits Vascular Endothelial Growth Factor Receptor Signaling and Growth of Anaplastic Thyroid Cancer in an Orthotopic Nude Mouse Model

Fernando Gomez-Rivera, Alfredo A. Santillan-Gomez, Maher N. Younes, Seungwon Kim, David Fooshee, Mei Zhao, Samar A. Jasser, Jeffrey N. Myers

Clin Cancer Res (2007) 13 (15): 4519–4527.

https://doi.org/10.1158/1078-0432.CCR-06-2636

Published: 01 August 2007

View article titled, The Tyrosine Kinase Inhibitor, AZD2171, Inhibits Vascular Endothelial Growth Factor Receptor Signaling and Growth of Anaplastic Thyroid Cancer in an Orthotopic Nude Mouse Model

Journal Articles

Liposomal Quercetin Efficiently Suppresses Growth of Solid Tumors in Murine Models

Zhi-ping Yuan, Li-juan Chen, Lin-yu Fan, Ming-hai Tang, Guang-li Yang, Han-su Yang, Xiao-bo Du, Guo-qing Wang, Wen-xiu Yao, Qu-mei Zhao, Bin Ye, Rui Wang, Peng Diao, Wei Zhang, Hong-bin Wu, Xia Zhao, Yu-Quan Wei

Clin Cancer Res (2006) 12 (10): 3193–3199.

https://doi.org/10.1158/1078-0432.CCR-05-2365

Published: 17 May 2006

View article titled, Liposomal Quercetin Efficiently Suppresses Growth of Solid Tumors in Murine Models

NARROW

COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms

High-Risk TP53 Mutations Are Associated with Extranodal Extension in Oral Cavity Squamous Cell Carcinoma

Abstract 73: Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cell by targeting forkhead transcription factors FOXO3a and FOXM1

Abstract 44: Synergistic antitumor activity of olaparib combined with AZD1775 in head and neck squamous cell carcinoma

Wee-1 Kinase Inhibition Sensitizes High-Risk HPV⁺ HNSCC to Apoptosis Accompanied by Downregulation of MCl-1 and XIAP Antiapoptotic Proteins

Squamous Cell Carcinoma of the Oral Tongue in Young Non-Smokers Is Genomically Similar to Tumors in Older Smokers

Establishment and Characterization of Novel Cell Lines from Sinonasal Undifferentiated Carcinoma

Assembly and Initial Characterization of a Panel of 85 Genomically Validated Cell Lines from Diverse Head and Neck Tumor Sites

Disruptive TP53 Mutation Is Associated with Aggressive Disease Characteristics in an Orthotopic Murine Model of Oral Tongue Cancer

Targeted Therapy of VEGFR2 and EGFR Significantly Inhibits Growth of Anaplastic Thyroid Cancer in an Orthotopic Murine Model

Vandetanib Restores Head and Neck Squamous Cell Carcinoma Cells' Sensitivity to Cisplatin and Radiation In Vivo and In Vitro

Vandetanib Inhibits Growth of Adenoid Cystic Carcinoma in an Orthotopic Nude Mouse Model

The Tyrosine Kinase Inhibitor, AZD2171, Inhibits Vascular Endothelial Growth Factor Receptor Signaling and Growth of Anaplastic Thyroid Cancer in an Orthotopic Nude Mouse Model

Liposomal Quercetin Efficiently Suppresses Growth of Solid Tumors in Murine Models

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