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Matthias Leisegang
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Journal Articles

One CD4+TCR and One CD8+TCR Targeting Autochthonous Neoantigens Are Essential and Sufficient for Tumor Eradication

Steven P. Wolf, Vasiliki Anastasopoulou, Kimberley Drousch, Markus I. Diehl, Boris Engels, Poh Yin Yew, Kazuma Kiyotani, Yusuke Nakamura, Karin Schreiber, Hans Schreiber, Matthias Leisegang
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (8): 1642–1654.
https://doi.org/10.1158/1078-0432.CCR-23-2905
Published: 15 April 2024
View article titled, One CD4<sup>+</sup>TCR and One CD8<sup>+</sup>TCR Targeting Autochthonous Neoantigens Are Essential and Sufficient for Tumor Eradication
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Includes: Multimedia, Supplementary data
Journal Articles

Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor–Engineered T Cells for Ovarian Cancer

Tatsuo Matsuda, Matthias Leisegang, Jae-Hyun Park, Lili Ren, Taigo Kato, Yuji Ikeda, Makiko Harada, Kazuma Kiyotani, Ernst Lengyel, Gini F. Fleming, Yusuke Nakamura
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (21): 5357–5367.
https://doi.org/10.1158/1078-0432.CCR-18-0142
Published: 01 November 2018
View article titled, Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor–Engineered T Cells for Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Targeting Merkel Cell Carcinoma by Engineered T Cells Specific to T-Antigens of Merkel Cell Polyomavirus

Ioannis Gavvovidis, Matthias Leisegang, Gerald Willimsky, Natalie Miller, Paul Nghiem, Thomas Blankenstein
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (15): 3644–3655.
https://doi.org/10.1158/1078-0432.CCR-17-2661
Published: 31 July 2018
View article titled, Targeting Merkel Cell Carcinoma by Engineered T Cells Specific to T-Antigens of Merkel Cell Polyomavirus
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Includes: Supplementary data
Journal Articles

Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation

Matthias Leisegang, Boris Engels, Karin Schreiber, Poh Yin Yew, Kazuma Kiyotani, Christian Idel, Ainhoa Arina, Jaikumar Duraiswamy, Ralph R. Weichselbaum, Wolfgang Uckert, Yusuke Nakamura, Hans Schreiber
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (11): 2734–2743.
https://doi.org/10.1158/1078-0432.CCR-15-2361
Published: 31 May 2016
View article titled, Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation
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Includes: Supplementary data
Journal Articles

T-Cell Receptor Gene–Modified T Cells with Shared Renal Cell Carcinoma Specificity for Adoptive T-Cell Therapy

Matthias Leisegang, Adriana Turqueti-Neves, Boris Engels, Thomas Blankenstein, Dolores J. Schendel, Wolfgang Uckert, Elfriede Noessner
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (8): 2333–2343.
https://doi.org/10.1158/1078-0432.CCR-09-2897
Published: 14 April 2010
View article titled, T-Cell Receptor Gene–Modified T Cells with Shared Renal Cell Carcinoma Specificity for Adoptive T-Cell Therapy
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Includes: Supplementary data