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Matthew L. Freedman
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Journal Articles

Detecting Small Cell Transformation in Patients with Advanced EGFR Mutant Lung Adenocarcinoma through Epigenomic cfDNA Profiling

Talal El Zarif, Catherine B. Meador, Xintao Qiu, Ji-Heui Seo, Matthew P. Davidsohn, Hunter Savignano, Gitanjali Lakshminarayanan, Heather M. McClure, John Canniff, Brad Fortunato, Rong Li, Mandeep K. Banwait, Karl Semaan, Marc Eid, Henry Long, Yin P. Hung, Navin R. Mahadevan, David A. Barbie, Matthew G. Oser, Zofia Piotrowska, Toni K. Choueiri, Sylvan C. Baca, Aaron N. Hata, Matthew L. Freedman, Jacob E. Berchuck
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (17): 3798–3811.
https://doi.org/10.1158/1078-0432.CCR-24-0466
Published: 03 September 2024
View article titled, Detecting Small Cell Transformation in Patients with Advanced <em>EGFR</em> Mutant Lung Adenocarcinoma through Epigenomic cfDNA Profiling
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Includes: Supplementary data
Journal Articles

Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis

Jacob E. Berchuck, Sylvan C. Baca, Heather M. McClure, Keegan Korthauer, Harrison K. Tsai, Pier Vitale Nuzzo, Kaitlin M. Kelleher, Monica He, John A. Steinharter, Soumya Zacharia, Sandor Spisak, Ji-Heui Seo, Vincenza Conteduca, Olivier Elemento, Joonghoon Auh, Michael Sigouros, Eva Corey, Michelle S. Hirsch, Mary-Ellen Taplin, Toni K. Choueiri, Mark M. Pomerantz, Himisha Beltran, Matthew L. Freedman
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (5): 928–938.
https://doi.org/10.1158/1078-0432.CCR-21-3762
Published: 03 March 2022
View article titled, Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis
Open the PDF for Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis in another window
Includes: Supplementary data
Journal Articles

Detection of Molecular Signatures of Homologous Recombination Deficiency in Prostate Cancer with or without BRCA1/2 Mutations

Zsofia Sztupinszki, Miklos Diossy, Marcin Krzystanek, Judit Borcsok, Mark M. Pomerantz, Viktoria Tisza, Sandor Spisak, Orsolya Rusz, István Csabai, Matthew L. Freedman, Zoltan Szallasi
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11): 2673–2680.
https://doi.org/10.1158/1078-0432.CCR-19-2135
Published: 01 June 2020
View article titled, Detection of Molecular Signatures of Homologous Recombination Deficiency in Prostate Cancer with or without BRCA1/2 Mutations
Open the PDF for Detection of Molecular Signatures of Homologous Recombination Deficiency in Prostate Cancer with or without BRCA1/2 Mutations in another window
Includes: Supplementary data
Journal Articles

Abstract AP11: IDENTIFYING FUNCTIONAL NONCODING SOMATIC MUTATIONS IN OVARIAN CANCER

Rosario I. Corona, Ji-Heui Seo, Dennis J. Hazelett, Xianzhi Lin, Paulette Y. Mhawech-Fauceglia, Jenny Lester, Sohrab P. Shah, David G. Huntsman, Beth Y. Karlan, Alexander Gusev, Benjamin P. Berman, Matthew L. Freedman, Simon A. Gayther, Kate Lawrenson
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22_Supplement): AP11.
https://doi.org/10.1158/1557-3265.OVCASYMP18-AP11
Published: 15 November 2019
View article titled, Abstract AP11: IDENTIFYING FUNCTIONAL NONCODING SOMATIC MUTATIONS IN OVARIAN CANCER
Journal Articles

Abstract GMM-042: PAN-CANCER TRANSCRIPTION FACTOR ANALYSES IDENTIFY ZNF217 AS A NOVEL DRIVER IN HGSOC

Robbin Nameki, Marcos A. S. Fonseca, Jessica Reddy, Kevin C. Vavra, Felipe Segato, Rosario I. Corona, Ji-Heui Seo, Annie Liu, Forough Abbasi, Xianzhi Lin, Beth Y. Karlan, Matthew L. Freedman, Simon A. Gayther, Houtan Noushmehr, Kate Lawrenson
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22_Supplement): GMM-042.
https://doi.org/10.1158/1557-3265.OVCASYMP18-GMM-042
Published: 15 November 2019
View article titled, Abstract GMM-042: PAN-CANCER TRANSCRIPTION FACTOR ANALYSES IDENTIFY ZNF217 AS A NOVEL DRIVER IN HGSOC
Journal Articles

A Novel Mechanism Driving Poor-Prognosis Prostate Cancer: Overexpression of the DNA Repair Gene, Ribonucleotide Reductase Small Subunit M2 (RRM2)

Ying Z. Mazzu, Joshua Armenia, Goutam Chakraborty, Yuki Yoshikawa, Si'Ana A. Coggins, Subhiksha Nandakumar, Travis A. Gerke, Mark M. Pomerantz, Xintao Qiu, Huiyong Zhao, Mohammad Atiq, Nabeela Khan, Kazumasa Komura, Gwo-Shu Mary Lee, Samson W. Fine, Connor Bell, Edward O'Connor, Henry W. Long, Matthew L. Freedman, Baek Kim, Philip W. Kantoff
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (14): 4480–4492.
https://doi.org/10.1158/1078-0432.CCR-18-4046
Published: 15 July 2019
View article titled, A Novel Mechanism Driving Poor-Prognosis Prostate Cancer: Overexpression of the DNA Repair Gene, Ribonucleotide Reductase Small Subunit M2 (RRM2)
Open the PDF for A Novel Mechanism Driving Poor-Prognosis Prostate Cancer: Overexpression of the DNA Repair Gene, Ribonucleotide Reductase Small Subunit M2 (RRM2) in another window
Includes: Supplementary data
Journal Articles

Inherited Variants in the Chemokine CCL2 Gene and Prostate Cancer Aggressiveness in a Caucasian Cohort

Tong Sun, Lee Gwo-Shu Mary, William K. Oh, Matthew L. Freedman, Mark Pomerantz, Kenneth J. Pienta, Philip W. Kantoff
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (6): 1546–1552.
https://doi.org/10.1158/1078-0432.CCR-10-2015
Published: 15 March 2011
View article titled, Inherited Variants in the Chemokine <em>CCL2</em> Gene and Prostate Cancer Aggressiveness in a Caucasian Cohort
Open the PDF for Inherited Variants in the Chemokine <em>CCL2</em> Gene and Prostate Cancer Aggressiveness in a Caucasian Cohort in another window
Journal Articles

Single-Nucleotide Polymorphisms in p53 Pathway and Aggressiveness of Prostate Cancer in a Caucasian Population

Tong Sun, Gwo-Shu Mary Lee, William K. Oh, Mark Pomerantz, Ming Yang, Wanling Xie, Matthew L. Freedman, Philip W. Kantoff
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (21): 5244–5251.
https://doi.org/10.1158/1078-0432.CCR-10-1261
Published: 31 October 2010
View article titled, Single-Nucleotide Polymorphisms in p53 Pathway and Aggressiveness of Prostate Cancer in a Caucasian Population
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Journal Articles

Evaluation of 8q24 and 17q Risk Loci and Prostate Cancer Mortality

Kathryn L. Penney, Claudia A. Salinas, Mark Pomerantz, Fredrick R. Schumacher, Christine A. Beckwith, Gwo-Shu Lee, William K. Oh, Oliver Sartor, Elaine A. Ostrander, Tobias Kurth, Jing Ma, Lorelei Mucci, Janet L. Stanford, Philip W. Kantoff, David J. Hunter, Meir J. Stampfer, Matthew L. Freedman
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (9): 3223–3230.
https://doi.org/10.1158/1078-0432.CCR-08-2733
Published: 30 April 2009
View article titled, Evaluation of 8q24 and 17q Risk Loci and Prostate Cancer Mortality
Open the PDF for Evaluation of 8q24 and 17q Risk Loci and Prostate Cancer Mortality in another window
Includes: Supplementary data