1-20 of 20
Martin W. Brechbiel
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008

Free
Ingrid J.G. Burvenich, Fook T. Lee, Glenn A. Cartwright, Graeme J. O'Keefe, Dahna Makris, Diana Cao, Sylvia Gong, Anderly C. Chueh, John M. Mariadason, Martin W. Brechbiel, Robert A. Beckman, Kosaku Fujiwara, Reinhard von Roemeling, Andrew M. Scott
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (21): 5984–5993.
https://doi.org/10.1158/1078-0432.CCR-12-3104
Published: 31 October 2013
View articletitled, Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008
Open the PDF for Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008 in another window
Includes: Supplementary data
Journal Articles

Molecular Pathways: Targeted α-Particle Radiation Therapy

Free
Kwamena E. Baidoo, Kwon Yong, Martin W. Brechbiel
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (3): 530–537.
https://doi.org/10.1158/1078-0432.CCR-12-0298
Published: 31 January 2013
View articletitled, Molecular Pathways: Targeted α-Particle Radiation Therapy
Open the PDF for Molecular Pathways: Targeted α-Particle Radiation Therapy in another window
Journal Articles

Phase I Biodistribution and Pharmacokinetic Study of Lewis Y–Targeting Immunoconjugate CMD-193 in Patients with Advanced Epithelial Cancers

Free
Rebecca A. Herbertson, Niall C. Tebbutt, Fook-Thean Lee, David J. MacFarlane, Bridget Chappell, Noel Micallef, Sze-Ting Lee, Timothy Saunder, Wendie Hopkins, Fiona E. Smyth, David K. Wyld, John Bellen, Daryl S. Sonnichsen, Martin W. Brechbiel, Carmel Murone, Andrew M. Scott
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (21): 6709–6715.
https://doi.org/10.1158/1078-0432.CCR-09-0536
Published: 02 November 2009
View articletitled, Phase I Biodistribution and Pharmacokinetic Study of Lewis Y–Targeting Immunoconjugate CMD-193 in Patients with Advanced Epithelial Cancers
Open the PDF for Phase I Biodistribution and Pharmacokinetic Study of Lewis Y–Targeting Immunoconjugate CMD-193 in Patients with Advanced Epithelial Cancers in another window
Journal Articles

Multimodality Therapy: Potentiation of High Linear Energy Transfer Radiation with Paclitaxel for the Treatment of Disseminated Peritoneal Disease

Free
Diane E. Milenic, Kayhan Garmestani, Erik D. Brady, Kwamena E. Baidoo, Paul S. Albert, Karen J. Wong, Joseph Flynn, Martin W. Brechbiel
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (16): 5108–5115.
https://doi.org/10.1158/1078-0432.CCR-08-0256
Published: 12 August 2008
View articletitled, Multimodality Therapy: Potentiation of High Linear Energy Transfer Radiation with Paclitaxel for the Treatment of Disseminated Peritoneal Disease
Open the PDF for Multimodality Therapy: Potentiation of High Linear Energy Transfer Radiation with Paclitaxel for the Treatment of Disseminated Peritoneal Disease in another window
Journal Articles

Effective Treatment of Established Human Breast Tumor Xenografts in Immunodeficient Mice with a Single Dose of the α-Emitting Radioisotope Astatine-211 Conjugated to Anti-HER2/neu Diabodies

Free
Matthew K. Robinson, Calvin Shaller, Kayhan Garmestani, Paul S. Plascjak, Kathryn M. Hodge, Qing-An Yuan, James D. Marks, Thomas A. Waldmann, Martin W. Brechbiel, Gregory P. Adams
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (3): 875–882.
https://doi.org/10.1158/1078-0432.CCR-07-1250
Published: 01 February 2008
View articletitled, Effective Treatment of Established Human Breast Tumor Xenografts in Immunodeficient Mice with a Single Dose of the α-Emitting Radioisotope Astatine-211 Conjugated to Anti-HER2/neu Diabodies
Open the PDF for Effective Treatment of Established Human Breast Tumor Xenografts in Immunodeficient Mice with a Single Dose of the α-Emitting Radioisotope Astatine-211 Conjugated to Anti-HER2/neu Diabodies in another window
Journal Articles

Radioimmunotherapy with α-Particle–Emitting 213Bi-C-Functionalized trans-Cyclohexyl-Diethylenetriaminepentaacetic Acid-Humanized 3S193 Is Enhanced by Combination with Paclitaxel Chemotherapy

Free
Marcus P. Kelly, Fook T. Lee, Kiki Tahtis, Fiona E. Smyth, Martin W. Brechbiel, Andrew M. Scott
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (18): 5604s–5612s.
https://doi.org/10.1158/1078-0432.CCR-07-1071
Published: 17 September 2007
View articletitled, Radioimmunotherapy with α-Particle–Emitting 213Bi-C-Functionalized trans-Cyclohexyl-Diethylenetriaminepentaacetic Acid-Humanized 3S193 Is Enhanced by Combination with Paclitaxel Chemotherapy
Open the PDF for Radioimmunotherapy with α-Particle–Emitting 213Bi-C-Functionalized trans-Cyclohexyl-Diethylenetriaminepentaacetic Acid-Humanized 3S193 Is Enhanced by Combination with Paclitaxel Chemotherapy in another window
Journal Articles

A Phase I Biodistribution and Pharmacokinetic Trial of Humanized Monoclonal Antibody Hu3s193 in Patients with Advanced Epithelial Cancers that Express the Lewis-Y Antigen

Free
Andrew M. Scott, Niall Tebbutt, Fook-Thean Lee, Tina Cavicchiolo, Zhanqi Liu, Sanjeev Gill, Aurora M.T. Poon, Wendie Hopkins, Fiona E. Smyth, Carmel Murone, Duncan MacGregor, Anthony T. Papenfuss, Bridget Chappell, Timothy H. Saunder, Martin W. Brechbiel, Ian D. Davis, Roger Murphy, Geoffrey Chong, Eric W. Hoffman, Lloyd J. Old
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (11): 3286–3292.
https://doi.org/10.1158/1078-0432.CCR-07-0284
Published: 01 June 2007
View articletitled, A Phase I Biodistribution and Pharmacokinetic Trial of Humanized Monoclonal Antibody Hu3s193 in Patients with Advanced Epithelial Cancers that Express the Lewis-Y Antigen
Open the PDF for A Phase I Biodistribution and Pharmacokinetic Trial of Humanized Monoclonal Antibody Hu3s193 in Patients with Advanced Epithelial Cancers that Express the Lewis-Y Antigen in another window
Journal Articles

Potentiation of High-LET Radiation by Gemcitabine: Targeting HER2 with Trastuzumab to Treat Disseminated Peritoneal Disease

Free
Diane E. Milenic, Kayhan Garmestani, Erik D. Brady, Paul S. Albert, Alia Abdulla, Joseph Flynn, Martin W. Brechbiel
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (6): 1926–1935.
https://doi.org/10.1158/1078-0432.CCR-06-2300
Published: 15 March 2007
View articletitled, Potentiation of High-LET Radiation by Gemcitabine: Targeting HER2 with Trastuzumab to Treat Disseminated Peritoneal Disease
Open the PDF for Potentiation of High-LET Radiation by Gemcitabine: Targeting HER2 with Trastuzumab to Treat Disseminated Peritoneal Disease in another window
Journal Articles

Real-time, Image-Guided, Convection-Enhanced Delivery of Interleukin 13 Bound to Pseudomonas Exotoxin

Free
Gregory J.A. Murad, Stuart Walbridge, Paul F. Morrison, Kayhan Garmestani, Jeffrey W. Degen, Martin W. Brechbiel, Edward H. Oldfield, Russell R. Lonser
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (10): 3145–3151.
https://doi.org/10.1158/1078-0432.CCR-05-2583
Published: 17 May 2006
View articletitled, Real-time, Image-Guided, Convection-Enhanced Delivery of Interleukin 13 Bound to Pseudomonas Exotoxin
Open the PDF for Real-time, Image-Guided, Convection-Enhanced Delivery of Interleukin 13 Bound to Pseudomonas Exotoxin in another window
Journal Articles

213Bi-[DOTA0, Tyr3]Octreotide Peptide Receptor Radionuclide Therapy of Pancreatic Tumors in a Preclinical Animal Model

Free
Jeffrey P. Norenberg, Boudewijn J. Krenning, Inge R.H.M. Konings, Donna F. Kusewitt, Tapan K. Nayak, Tamara L. Anderson, Marion de Jong, Kayhan Garmestani, Martin W. Brechbiel, Larry K. Kvols
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (3): 897–903.
https://doi.org/10.1158/1078-0432.CCR-05-1264
Published: 07 February 2006
View articletitled, 213Bi-[DOTA0, Tyr3]Octreotide Peptide Receptor Radionuclide Therapy of Pancreatic Tumors in a Preclinical Animal Model
Open the PDF for 213Bi-[DOTA0, Tyr3]Octreotide Peptide Receptor Radionuclide Therapy of Pancreatic Tumors in a Preclinical Animal Model in another window
Journal Articles

Radioimmunotherapy of CD22-Expressing Daudi Tumors in Nude Mice with a 90Y-Labeled Anti-CD22 Monoclonal Antibody

Free
Daniel A. Vallera, Martin W. Brechbiel, Linda J. Burns, Angela Panoskaltsis-Mortari, Katie E. Dusenbery, Dennis R. Clohisy, Ellen S. Vitetta
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (21): 7920–7928.
https://doi.org/10.1158/1078-0432.CCR-05-0725
Published: 08 November 2005
View articletitled, Radioimmunotherapy of CD22-Expressing Daudi Tumors in Nude Mice with a 90Y-Labeled Anti-CD22 Monoclonal Antibody
Open the PDF for Radioimmunotherapy of CD22-Expressing Daudi Tumors in Nude Mice with a 90Y-Labeled Anti-CD22 Monoclonal Antibody in another window
Journal Articles

Enhanced Efficacy of Radioimmunotherapy with 90Y-CHX-A″-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478

Free
Fook T. Lee, Angela J. Mountain, Marcus P. Kelly, Cathrine Hall, Angela Rigopoulos, Terrance G. Johns, Fiona E. Smyth, Martin W. Brechbiel, Edouard C. Nice, Antony W. Burgess, Andrew M. Scott
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (19): 7080s–7086s.
https://doi.org/10.1158/1078-0432.CCR-1004-0019
Published: 03 October 2005
View articletitled, Enhanced Efficacy of Radioimmunotherapy with 90Y-CHX-A″-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478
Open the PDF for Enhanced Efficacy of Radioimmunotherapy with 90Y-CHX-A″-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478 in another window
Journal Articles

Targeting of HER2 Antigen for the Treatment of Disseminated Peritoneal Disease

Free
Diane E. Milenic, Kayhan Garmestani, Erik D. Brady, Paul S. Albert, Dangshe Ma, Alia Abdulla, Martin W. Brechbiel
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (23): 7834–7841.
https://doi.org/10.1158/1078-0432.CCR-04-1226
Published: 07 December 2004
View articletitled, Targeting of HER2 Antigen for the Treatment of Disseminated Peritoneal Disease
Open the PDF for Targeting of HER2 Antigen for the Treatment of Disseminated Peritoneal Disease in another window
Journal Articles

Application of a Macromolecular Contrast Agent for Detection of Alterations of Tumor Vessel Permeability Induced by Radiation

Free
Hisataka Kobayashi, Koen Reijnders, Sean English, Alexander T. Yordanov, Diane E. Milenic, Anastasia L. Sowers, Deborah Citrin, Murali C. Krishna, Thomas A. Waldmann, James B. Mitchell, Martin W. Brechbiel
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (22): 7712–7720.
https://doi.org/10.1158/1078-0432.CCR-04-1175
Published: 29 November 2004
View articletitled, Application of a Macromolecular Contrast Agent for Detection of Alterations of Tumor Vessel Permeability Induced by Radiation
Open the PDF for Application of a Macromolecular Contrast Agent for Detection of Alterations of Tumor Vessel Permeability Induced by Radiation in another window
Journal Articles

Pretargeted α Emitting Radioimmunotherapy Using 213Bi 1,4,7,10-Tetraazacyclododecane- N , N ′, N ″, N ‴-Tetraacetic Acid-Biotin

Free
Zhengsheng Yao, Meili Zhang, Kayhan Garmestani, Donald B. Axworthy, Robert W. Mallett, Alan R. Fritzberg, Lou J. Theodore, Paul S. Plascjak, William C. Eckelman, Thomas A. Waldmann, Ira Pastan, Chang H. Paik, Martin W. Brechbiel, Jorge A. Carrasquillo
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (9): 3137–3146.
https://doi.org/10.1158/1078-0432.CCR-03-0171
Published: 06 May 2004
View articletitled, Pretargeted α Emitting Radioimmunotherapy Using 213Bi 1,4,7,10-Tetraazacyclododecane- N , N ′, N ″, N ‴-Tetraacetic Acid-Biotin
Open the PDF for Pretargeted α Emitting Radioimmunotherapy Using 213Bi 1,4,7,10-Tetraazacyclododecane- N , N ′, N ″, N ‴-Tetraacetic Acid-Biotin in another window
Journal Articles

Radiolabeling of Avidin with Very High Specific Activity for Internal Radiation Therapy of Intraperitoneally Disseminated Tumors

Free
Marcelo Mamede, Tsuneo Saga, Hisataka Kobayashi, Takayoshi Ishimori, Tatsuya Higashi, Noriko Sato, Martin W. Brechbiel, Junji Konishi
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (10): 3756–3762.
Published: 23 September 2003
View articletitled, Radiolabeling of Avidin with Very High Specific Activity for Internal Radiation Therapy of Intraperitoneally Disseminated Tumors
Open the PDF for Radiolabeling of Avidin with Very High Specific Activity for Internal Radiation Therapy of Intraperitoneally Disseminated Tumors in another window
Journal Articles

Tumor Targeting and Imaging of Intraperitoneal Tumors by Use of Antisense Oligo-DNA Complexed with Dendrimers and/or Avidin in Mice

Free
Noriko Sato, Hisataka Kobayashi, Tsuneo Saga, Yuji Nakamoto, Takayoshi Ishimori, Kaori Togashi, Yasuhisa Fujibayashi, Junji Konishi, Martin W. Brechbiel
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (11): 3606–3612.
Published: 01 November 2001
View articletitled, Tumor Targeting and Imaging of Intraperitoneal Tumors by Use of Antisense Oligo-DNA Complexed with Dendrimers and/or Avidin in Mice
Open the PDF for Tumor Targeting and Imaging of Intraperitoneal Tumors by Use of Antisense Oligo-DNA Complexed with Dendrimers and/or Avidin in Mice in another window
Journal Articles

Biodistribution Properties of 111Indium-labeled C-Functionalized trans-Cyclohexyl Diethylenetriaminepentaacetic Acid Humanized 3S193 Diabody and F(ab′)2 Constructs in a Breast Carcinoma Xenograft Model

Free
Kiki Tahtis, Fook-Thean Lee, Fiona E. Smyth, Barbara E. Power, Christoph Renner, Martin W. Brechbiel, Lloyd J. Old, Peter J. Hudson, Andrew M. Scott
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (4): 1061–1072.
Published: 01 April 2001
View articletitled, Biodistribution Properties of 111Indium-labeled C-Functionalized trans-Cyclohexyl Diethylenetriaminepentaacetic Acid Humanized 3S193 Diabody and F(ab′)2 Constructs in a Breast Carcinoma Xenograft Model
Open the PDF for Biodistribution Properties of 111Indium-labeled C-Functionalized trans-Cyclohexyl Diethylenetriaminepentaacetic Acid Humanized 3S193 Diabody and F(ab′)2 Constructs in a Breast Carcinoma Xenograft Model in another window
Journal Articles

Therapeutic Efficacy of Anti-Lewisy Humanized 3S193 Radioimmunotherapy in a Breast Cancer Model: Enhanced Activity When Combined with Taxol Chemotherapy

Free
Kerrie Clarke, Fook-Thean Lee, Martin W. Brechbiel, Fiona E. Smyth, Lloyd J. Old, Andrew M. Scott
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (9): 3621–3628.
Published: 01 September 2000
View articletitled, Therapeutic Efficacy of Anti-Lewisy Humanized 3S193 Radioimmunotherapy in a Breast Cancer Model: Enhanced Activity When Combined with Taxol Chemotherapy
Open the PDF for Therapeutic Efficacy of Anti-Lewisy Humanized 3S193 Radioimmunotherapy in a Breast Cancer Model: Enhanced Activity When Combined with Taxol Chemotherapy in another window
Journal Articles

Targeting Strategies for Cancer Radiotherapy

Free
Donald J. Buchsbaum, Buck E. Rogers, M. B. Khazaeli, Matthew S. Mayo, Diane E. Milenic, S. V. S. Kashmiri, Carolyn J. Anderson, Lara L. Chappell, Martin W. Brechbiel, David T. Curiel
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (10): 3048s–3055s.
Published: 01 October 1999
View articletitled, Targeting Strategies for Cancer Radiotherapy
Open the PDF for Targeting Strategies for Cancer Radiotherapy in another window