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Journal Articles

Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008

Ingrid J.G. Burvenich, Fook T. Lee, Glenn A. Cartwright, Graeme J. O'Keefe, Dahna Makris, Diana Cao, Sylvia Gong, Anderly C. Chueh, John M. Mariadason, Martin W. Brechbiel, Robert A. Beckman, Kosaku Fujiwara, Reinhard von Roemeling, Andrew M. Scott

Clin Cancer Res (2013) 19 (21): 5984–5993.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-3104

Published: 31 October 2013

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Includes: Supplementary data

Journal Articles

Molecular Pathways: Targeted α-Particle Radiation Therapy

Kwamena E. Baidoo, Kwon Yong, Martin W. Brechbiel

Clin Cancer Res (2013) 19 (3): 530–537.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-0298

Published: 31 January 2013

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Journal Articles

Phase I Biodistribution and Pharmacokinetic Study of Lewis Y–Targeting Immunoconjugate CMD-193 in Patients with Advanced Epithelial Cancers

Rebecca A. Herbertson, Niall C. Tebbutt, Fook-Thean Lee, David J. MacFarlane, Bridget Chappell, Noel Micallef, Sze-Ting Lee, Timothy Saunder, Wendie Hopkins, Fiona E. Smyth, David K. Wyld, John Bellen, Daryl S. Sonnichsen, Martin W. Brechbiel, Carmel Murone, Andrew M. Scott

Clin Cancer Res (2009) 15 (21): 6709–6715.

DOI: https://doi.org/10.1158/1078-0432.CCR-09-0536

Published: 02 November 2009

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Journal Articles

Multimodality Therapy: Potentiation of High Linear Energy Transfer Radiation with Paclitaxel for the Treatment of Disseminated Peritoneal Disease

Diane E. Milenic, Kayhan Garmestani, Erik D. Brady, Kwamena E. Baidoo, Paul S. Albert, Karen J. Wong, Joseph Flynn, Martin W. Brechbiel

Clin Cancer Res (2008) 14 (16): 5108–5115.

DOI: https://doi.org/10.1158/1078-0432.CCR-08-0256

Published: 12 August 2008

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Journal Articles

Effective Treatment of Established Human Breast Tumor Xenografts in Immunodeficient Mice with a Single Dose of the α-Emitting Radioisotope Astatine-211 Conjugated to Anti-HER2/neu Diabodies

Matthew K. Robinson, Calvin Shaller, Kayhan Garmestani, Paul S. Plascjak, Kathryn M. Hodge, Qing-An Yuan, James D. Marks, Thomas A. Waldmann, Martin W. Brechbiel, Gregory P. Adams

Clin Cancer Res (2008) 14 (3): 875–882.

DOI: https://doi.org/10.1158/1078-0432.CCR-07-1250

Published: 01 February 2008

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Journal Articles

Radioimmunotherapy with α-Particle–Emitting ²¹³Bi-C-Functionalized trans-Cyclohexyl-Diethylenetriaminepentaacetic Acid-Humanized 3S193 Is Enhanced by Combination with Paclitaxel Chemotherapy

Marcus P. Kelly, Fook T. Lee, Kiki Tahtis, Fiona E. Smyth, Martin W. Brechbiel, Andrew M. Scott

Clin Cancer Res (2007) 13 (18): 5604s–5612s.

DOI: https://doi.org/10.1158/1078-0432.CCR-07-1071

Published: 17 September 2007

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Journal Articles

A Phase I Biodistribution and Pharmacokinetic Trial of Humanized Monoclonal Antibody Hu3s193 in Patients with Advanced Epithelial Cancers that Express the Lewis-Y Antigen

Clin Cancer Res (2007) 13 (11): 3286–3292.

DOI: https://doi.org/10.1158/1078-0432.CCR-07-0284

Published: 01 June 2007

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Journal Articles

Potentiation of High-LET Radiation by Gemcitabine: Targeting HER2 with Trastuzumab to Treat Disseminated Peritoneal Disease

Diane E. Milenic, Kayhan Garmestani, Erik D. Brady, Paul S. Albert, Alia Abdulla, Joseph Flynn, Martin W. Brechbiel

Clin Cancer Res (2007) 13 (6): 1926–1935.

DOI: https://doi.org/10.1158/1078-0432.CCR-06-2300

Published: 15 March 2007

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Journal Articles

Real-time, Image-Guided, Convection-Enhanced Delivery of Interleukin 13 Bound to Pseudomonas Exotoxin

Gregory J.A. Murad, Stuart Walbridge, Paul F. Morrison, Kayhan Garmestani, Jeffrey W. Degen, Martin W. Brechbiel, Edward H. Oldfield, Russell R. Lonser

Clin Cancer Res (2006) 12 (10): 3145–3151.

DOI: https://doi.org/10.1158/1078-0432.CCR-05-2583

Published: 17 May 2006

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Journal Articles

²¹³Bi-[DOTA⁰, Tyr³]Octreotide Peptide Receptor Radionuclide Therapy of Pancreatic Tumors in a Preclinical Animal Model

Jeffrey P. Norenberg, Boudewijn J. Krenning, Inge R.H.M. Konings, Donna F. Kusewitt, Tapan K. Nayak, Tamara L. Anderson, Marion de Jong, Kayhan Garmestani, Martin W. Brechbiel, Larry K. Kvols

Clin Cancer Res (2006) 12 (3): 897–903.

DOI: https://doi.org/10.1158/1078-0432.CCR-05-1264

Published: 07 February 2006

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Journal Articles

Radioimmunotherapy of CD22-Expressing Daudi Tumors in Nude Mice with a ⁹⁰Y-Labeled Anti-CD22 Monoclonal Antibody

Daniel A. Vallera, Martin W. Brechbiel, Linda J. Burns, Angela Panoskaltsis-Mortari, Katie E. Dusenbery, Dennis R. Clohisy, Ellen S. Vitetta

Clin Cancer Res (2005) 11 (21): 7920–7928.

DOI: https://doi.org/10.1158/1078-0432.CCR-05-0725

Published: 08 November 2005

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Journal Articles

Enhanced Efficacy of Radioimmunotherapy with ⁹⁰Y-CHX-A″-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478

Fook T. Lee, Angela J. Mountain, Marcus P. Kelly, Cathrine Hall, Angela Rigopoulos, Terrance G. Johns, Fiona E. Smyth, Martin W. Brechbiel, Edouard C. Nice, Antony W. Burgess, Andrew M. Scott

Clin Cancer Res (2005) 11 (19): 7080s–7086s.

DOI: https://doi.org/10.1158/1078-0432.CCR-1004-0019

Published: 03 October 2005

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Journal Articles

Targeting of HER2 Antigen for the Treatment of Disseminated Peritoneal Disease

Diane E. Milenic, Kayhan Garmestani, Erik D. Brady, Paul S. Albert, Dangshe Ma, Alia Abdulla, Martin W. Brechbiel

Clin Cancer Res (2004) 10 (23): 7834–7841.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-1226

Published: 07 December 2004

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Journal Articles

Application of a Macromolecular Contrast Agent for Detection of Alterations of Tumor Vessel Permeability Induced by Radiation

Hisataka Kobayashi, Koen Reijnders, Sean English, Alexander T. Yordanov, Diane E. Milenic, Anastasia L. Sowers, Deborah Citrin, Murali C. Krishna, Thomas A. Waldmann, James B. Mitchell, Martin W. Brechbiel

Clin Cancer Res (2004) 10 (22): 7712–7720.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-1175

Published: 29 November 2004

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Journal Articles

Pretargeted α Emitting Radioimmunotherapy Using ²¹³Bi 1,4,7,10-Tetraazacyclododecane- N , N ′, N ″, N ‴-Tetraacetic Acid-Biotin

Zhengsheng Yao, Meili Zhang, Kayhan Garmestani, Donald B. Axworthy, Robert W. Mallett, Alan R. Fritzberg, Lou J. Theodore, Paul S. Plascjak, William C. Eckelman, Thomas A. Waldmann, Ira Pastan, Chang H. Paik, Martin W. Brechbiel, Jorge A. Carrasquillo

Clin Cancer Res (2004) 10 (9): 3137–3146.

DOI: https://doi.org/10.1158/1078-0432.CCR-03-0171

Published: 06 May 2004

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Journal Articles

Radiolabeling of Avidin with Very High Specific Activity for Internal Radiation Therapy of Intraperitoneally Disseminated Tumors

Marcelo Mamede, Tsuneo Saga, Hisataka Kobayashi, Takayoshi Ishimori, Tatsuya Higashi, Noriko Sato, Martin W. Brechbiel, Junji Konishi

Clin Cancer Res (2003) 9 (10): 3756–3762.

Published: 23 September 2003

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Journal Articles

Tumor Targeting and Imaging of Intraperitoneal Tumors by Use of Antisense Oligo-DNA Complexed with Dendrimers and/or Avidin in Mice

Noriko Sato, Hisataka Kobayashi, Tsuneo Saga, Yuji Nakamoto, Takayoshi Ishimori, Kaori Togashi, Yasuhisa Fujibayashi, Junji Konishi, Martin W. Brechbiel

Clin Cancer Res (2001) 7 (11): 3606–3612.

Published: 01 November 2001

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Journal Articles

Biodistribution Properties of ¹¹¹Indium-labeled C-Functionalized trans-Cyclohexyl Diethylenetriaminepentaacetic Acid Humanized 3S193 Diabody and F(ab′)₂ Constructs in a Breast Carcinoma Xenograft Model

Kiki Tahtis, Fook-Thean Lee, Fiona E. Smyth, Barbara E. Power, Christoph Renner, Martin W. Brechbiel, Lloyd J. Old, Peter J. Hudson, Andrew M. Scott

Clin Cancer Res (2001) 7 (4): 1061–1072.

Published: 01 April 2001

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Journal Articles

Therapeutic Efficacy of Anti-Lewis^y Humanized 3S193 Radioimmunotherapy in a Breast Cancer Model: Enhanced Activity When Combined with Taxol Chemotherapy

Kerrie Clarke, Fook-Thean Lee, Martin W. Brechbiel, Fiona E. Smyth, Lloyd J. Old, Andrew M. Scott

Clin Cancer Res (2000) 6 (9): 3621–3628.

Published: 01 September 2000

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Journal Articles

Targeting Strategies for Cancer Radiotherapy

Donald J. Buchsbaum, Buck E. Rogers, M. B. Khazaeli, Matthew S. Mayo, Diane E. Milenic, S. V. S. Kashmiri, Carolyn J. Anderson, Lara L. Chappell, Martin W. Brechbiel, David T. Curiel

Clin Cancer Res (1999) 5 (10): 3048s–3055s.

Published: 01 October 1999

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NARROW

Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008

Molecular Pathways: Targeted α-Particle Radiation Therapy

Phase I Biodistribution and Pharmacokinetic Study of Lewis Y–Targeting Immunoconjugate CMD-193 in Patients with Advanced Epithelial Cancers

Multimodality Therapy: Potentiation of High Linear Energy Transfer Radiation with Paclitaxel for the Treatment of Disseminated Peritoneal Disease

Effective Treatment of Established Human Breast Tumor Xenografts in Immunodeficient Mice with a Single Dose of the α-Emitting Radioisotope Astatine-211 Conjugated to Anti-HER2/neu Diabodies

Radioimmunotherapy with α-Particle–Emitting ²¹³Bi-C-Functionalized trans-Cyclohexyl-Diethylenetriaminepentaacetic Acid-Humanized 3S193 Is Enhanced by Combination with Paclitaxel Chemotherapy

A Phase I Biodistribution and Pharmacokinetic Trial of Humanized Monoclonal Antibody Hu3s193 in Patients with Advanced Epithelial Cancers that Express the Lewis-Y Antigen

Potentiation of High-LET Radiation by Gemcitabine: Targeting HER2 with Trastuzumab to Treat Disseminated Peritoneal Disease

Real-time, Image-Guided, Convection-Enhanced Delivery of Interleukin 13 Bound to Pseudomonas Exotoxin

²¹³Bi-[DOTA⁰, Tyr³]Octreotide Peptide Receptor Radionuclide Therapy of Pancreatic Tumors in a Preclinical Animal Model

Radioimmunotherapy of CD22-Expressing Daudi Tumors in Nude Mice with a ⁹⁰Y-Labeled Anti-CD22 Monoclonal Antibody

Enhanced Efficacy of Radioimmunotherapy with ⁹⁰Y-CHX-A″-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478

Targeting of HER2 Antigen for the Treatment of Disseminated Peritoneal Disease

Application of a Macromolecular Contrast Agent for Detection of Alterations of Tumor Vessel Permeability Induced by Radiation

Pretargeted α Emitting Radioimmunotherapy Using ²¹³Bi 1,4,7,10-Tetraazacyclododecane- N , N ′, N ″, N ‴-Tetraacetic Acid-Biotin

Radiolabeling of Avidin with Very High Specific Activity for Internal Radiation Therapy of Intraperitoneally Disseminated Tumors

Tumor Targeting and Imaging of Intraperitoneal Tumors by Use of Antisense Oligo-DNA Complexed with Dendrimers and/or Avidin in Mice

Biodistribution Properties of ¹¹¹Indium-labeled C-Functionalized trans-Cyclohexyl Diethylenetriaminepentaacetic Acid Humanized 3S193 Diabody and F(ab′)₂ Constructs in a Breast Carcinoma Xenograft Model

Therapeutic Efficacy of Anti-Lewis^y Humanized 3S193 Radioimmunotherapy in a Breast Cancer Model: Enhanced Activity When Combined with Taxol Chemotherapy

Targeting Strategies for Cancer Radiotherapy

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