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Mark T.A. Donoghue
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Journal Articles

Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer

Andrew T. Lenis, Vignesh Ravichandran, Samantha Brown, Syed M. Alam, Andrew Katims, Hong Truong, Peter A. Reisz, Samantha Vasselman, Barbara Nweji, Karen A. Autio, Michael J. Morris, Susan F. Slovin, Dana Rathkopf, Daniel Danila, Sungmin Woo, Hebert A. Vargas, Vincent P. Laudone, Behfar Ehdaie, Victor Reuter, Maria Arcila, Michael F. Berger, Agnes Viale, Howard I. Scher, Nikolaus Schultz, Anuradha Gopalan, Mark T.A. Donoghue, Irina Ostrovnaya, Konrad H. Stopsack, David B. Solit, Wassim Abida
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (17): 3894–3903.
https://doi.org/10.1158/1078-0432.CCR-23-3403
Published: 03 September 2024
View article titled, Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer
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Includes: Supplementary data
Journal Articles

Tumor-Agnostic Genomic and Clinical Analysis of BRAF Fusions Identifies Actionable Targets

Monica F. Chen, Soo-Ryum Yang, Jessica J. Tao, Antoine Desilets, Eli L. Diamond, Clare Wilhelm, Ezra Rosen, Yixiao Gong, Kerry Mullaney, Jean Torrisi, Robert J. Young, Romel Somwar, Helena A. Yu, Mark G. Kris, Gregory J. Riely, Maria E. Arcila, Marc Ladanyi, Mark T.A. Donoghue, Neal Rosen, Rona Yaeger, Alexander Drilon, Yonina R. Murciano-Goroff, Michael Offin
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (17): 3812–3823.
https://doi.org/10.1158/1078-0432.CCR-23-3981
Published: 03 September 2024
View article titled, Tumor-Agnostic Genomic and Clinical Analysis of <em>BRAF</em> Fusions Identifies Actionable Targets
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Includes: Supplementary data
Journal Articles

Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma

Caroline E. Gleason, Mark A. Dickson, Mary E. Klein (Dooley), Cristina R. Antonescu, Rodrigo Gularte-Mérida, Marimar Benitez, Juliana I. Delgado, Raghu P. Kataru, Mark Wei Yi Tan, Martina Bradic, Travis E. Adamson, Kenneth Seier, Allison L. Richards, Marta Palafox, Eric Chan, Sandra P. D'Angelo, Mrinal M. Gounder, Mary Louise Keohan, Ciara M. Kelly, Ping Chi, Sujana Movva, Jonathan Landa, Aimee M. Crago, Mark T.A. Donoghue, Li-Xuan Qin, Violetta Serra, Mesruh Turkekul, Afsar Barlas, Daniel M. Firester, Katia Manova-Todorova, Babak J. Mehrara, Marta Kovatcheva, Nguan Soon Tan, Samuel Singer, William D. Tap, Andrew Koff
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (4): 703–718.
https://doi.org/10.1158/1078-0432.CCR-23-2378
Published: 16 February 2024
View article titled, Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma
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Includes: Supplementary data
Journal Articles

Assessing the Genomic Landscape of Cervical Cancers: Clinical Opportunities and Therapeutic Targets

Claire F. Friedman, Vignesh Ravichandran, Kathryn Miller, Chad Vanderbilt, Qin Zhou, Alexia Iasonos, Malavika Vivek, Pamela Mishra, Mario M. Leitao, Jr, Vance Broach, Yukio Sonoda, Chrisann Kyi, Dmitriy Zamarin, Roisin E. O'Cearbhaill, Jason Konner, Michael F. Berger, Britta Weigelt, Amir Momeni Boroujeni, Kay J. Park, Carol Aghajanian, David B. Solit, Mark T.A. Donoghue
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (22): 4660–4668.
https://doi.org/10.1158/1078-0432.CCR-23-1078
Published: 14 November 2023
View article titled, Assessing the Genomic Landscape of Cervical Cancers: Clinical Opportunities and Therapeutic Targets
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Includes: Supplementary data
Journal Articles

Clinical and Molecular Features of Long-term Response to Immune Checkpoint Inhibitors in Patients with Advanced Non–Small Cell Lung Cancer

Rohit Thummalapalli, Biagio Ricciuti, Chaitanya Bandlamudi, Daniel Muldoon, Hira Rizvi, Arielle Elkrief, Jia Luo, Joao V. Alessi, Federica Pecci, Giuseppe Lamberti, Alessandro Di Federico, Lingzhi Hong, Jianjun Zhang, John V. Heymach, Don L. Gibbons, Andrew J. Plodkowski, Vignesh Ravichandran, Mark T.A. Donoghue, Chad Vanderbilt, Marc Ladanyi, Charles M. Rudin, Mark G. Kris, Gregory J. Riely, Jamie E. Chaft, Matthew D. Hellmann, Natalie I. Vokes, Mark M. Awad, Adam J. Schoenfeld
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (21): 4408–4418.
https://doi.org/10.1158/1078-0432.CCR-23-1207
Published: 01 November 2023
View article titled, Clinical and Molecular Features of Long-term Response to Immune Checkpoint Inhibitors in Patients with Advanced Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Overcoming Barriers to Tumor Genomic Profiling through Direct-to-Patient Outreach

Seyram A. Doe-Tetteh, Sabrina Y. Camp, Dalicia Reales, Jett Crowdis, Anne Marie Noronha, Bernadette Wolff, Tina Alano, Jesse Galle, S. Duygu Selcuklu, Agnes Viale, Nicholas D. Socci, Ying L. Liu, William P. Tew, Carol Aghajanian, Marc Ladanyi, Meng Xiao He, Saud H. AlDubayan, Roei David Mazor, Ofer Shpilberg, Oshrat Hershkovitz-Rokah, Jose A. Riancho, Jose L. Hernandez, M. Carmen Gonzalez-Vela, Justin J. Buthorn, Manda Wilson, Amy E. Webber, Mariko Yabe, Kseniya Petrova-Drus, Marc Rosenblum, Benjamin H. Durham, Omar Abdel-Wahab, Michael F. Berger, Mark T.A. Donoghue, Andrew L. Kung, Julia Glade Bender, Neerav N. Shukla, Samuel A. Funt, Ahmet Dogan, Robert A. Soslow, Hikmat Al-Ahmadie, Darren R. Feldman, Eliezer M. Van Allen, Eli L. Diamond, David B. Solit
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (13): 2445–2455.
https://doi.org/10.1158/1078-0432.CCR-22-3247
Published: 05 July 2023
View article titled, Overcoming Barriers to Tumor Genomic Profiling through Direct-to-Patient Outreach
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Includes: Supplementary data
Journal Articles

Long-term Follow-up and Patterns of Response, Progression, and Hyperprogression in Patients after PD-1 Blockade in Advanced Sarcoma

Nicholas D. Klemen, Sinchun Hwang, Martina Bradic, Evan Rosenbaum, Mark A. Dickson, Mrinal M. Gounder, Ciara M. Kelly, Mary L. Keohan, Sujana Movva, Katherine A. Thornton, Ping Chi, Benjamin A. Nacev, Jason E. Chan, Edmund K. Bartlett, Allison L. Richards, Samuel Singer, Mark T.A. Donoghue, William D. Tap, Sandra P. D'Angelo
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (5): 939–947.
https://doi.org/10.1158/1078-0432.CCR-21-3445
Published: 01 March 2022
View article titled, Long-term Follow-up and Patterns of Response, Progression, and Hyperprogression in Patients after PD-1 Blockade in Advanced Sarcoma
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Includes: Supplementary data
Journal Articles

The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer

Adam J. Schoenfeld, Chai Bandlamudi, Jessica A. Lavery, Joseph Montecalvo, Azadeh Namakydoust, Hira Rizvi, Jacklynn Egger, Carla P. Concepcion, Sonal Paul, Maria E. Arcila, Yahya Daneshbod, Jason Chang, Jennifer L. Sauter, Amanda Beras, Marc Ladanyi, Tyler Jacks, Charles M. Rudin, Barry S. Taylor, Mark T.A. Donoghue, Glenn Heller, Matthew D. Hellmann, Natasha Rekhtman, Gregory J. Riely
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (21): 5701–5708.
https://doi.org/10.1158/1078-0432.CCR-20-1825
Published: 02 November 2020
View article titled, The Genomic Landscape of <em>SMARCA4</em> Alterations and Associations with Outcomes in Patients with Lung Cancer
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Includes: Supplementary data
Journal Articles

Abstract IA04: COVID-19 in patients with lung cancers in New York City

Jia Luo, Hira Rizvi, Isabel R. Preeshagul, Jacklynn V. Egger, David Hoyos, Chaitanya Bandlamudi, Mark T.A. Donoghue, Marta Łuksza, Benjamin D. Greenbaum, Jedd D. Wolchok, Mark G. Kris, Matthew D. Hellmann
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (18_Supplement): IA04.
https://doi.org/10.1158/1557-3265.COVID-19-IA04
Published: 15 September 2020
View article titled, Abstract IA04: COVID-19 in patients with lung cancers in New York City
Journal Articles

Genomic Landscape of Uterine Sarcomas Defined Through Prospective Clinical Sequencing

Martee L. Hensley, Shweta S. Chavan, David B. Solit, Rajmohan Murali, Robert Soslow, Sarah Chiang, Achim A. Jungbluth, Chaitanya Bandlamudi, Preethi Srinivasan, William D. Tap, Evan Rosenbaum, Barry S. Taylor, Mark T.A. Donoghue, David M. Hyman
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (14): 3881–3888.
https://doi.org/10.1158/1078-0432.CCR-19-3959
Published: 15 July 2020
View article titled, Genomic Landscape of Uterine Sarcomas Defined Through Prospective Clinical Sequencing
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Includes: Supplementary data
Journal Articles

A Phase II Trial of Albumin-Bound Paclitaxel and Gemcitabine in Patients with Newly Diagnosed Stage IV Squamous Cell Lung Cancers

Paul K. Paik, Rachel K. Kim, Linda Ahn, Andrew J. Plodkowski, Ai Ni, Mark T.A. Donoghue, Philip Jonsson, Miguel Villalona-Calero, Kenneth Ng, Daniel McFarland, John J. Fiore, Afsheen Iqbal, Juliana Eng, Mark G. Kris, Charles M. Rudin
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (8): 1796–1802.
https://doi.org/10.1158/1078-0432.CCR-19-3060
Published: 15 April 2020
View article titled, A Phase II Trial of Albumin-Bound Paclitaxel and Gemcitabine in Patients with Newly Diagnosed Stage IV Squamous Cell Lung Cancers
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Includes: Supplementary data
Journal Articles

Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma

François Audenet, Sumit Isharwal, Eugene K. Cha, Mark T.A. Donoghue, Esther N. Drill, Irina Ostrovnaya, Eugene J. Pietzak, John P. Sfakianos, Aditya Bagrodia, Paari Murugan, Guido Dalbagni, Timothy F. Donahue, Jonathan E. Rosenberg, Dean F. Bajorin, Maria E. Arcila, Jaclyn F. Hechtman, Michael F. Berger, Barry S. Taylor, Hikmat Al-Ahmadie, Gopa Iyer, Bernard H. Bochner, Jonathan A. Coleman, David B. Solit
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (3): 967–976.
https://doi.org/10.1158/1078-0432.CCR-18-2039
Published: 01 February 2019
View article titled, Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma
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Includes: Supplementary data
Journal Articles

Clinical Utility of Prospective Molecular Characterization in Advanced Endometrial Cancer

Tara E. Soumerai, Mark T.A. Donoghue, Chaitanya Bandlamudi, Preethi Srinivasan, Matthew T. Chang, Dmitriy Zamarin, Karen A. Cadoo, Rachel N. Grisham, Roisin E. O'Cearbhaill, William P. Tew, Jason A. Konner, Martee L. Hensley, Vicky Makker, Paul Sabbatini, David R. Spriggs, Tiffany A. Troso-Sandoval, Alexandra Snyder Charen, Claire Friedman, Mila Gorsky, Sarah J. Schweber, Sumit Middha, Rajmohan Murali, Sarah Chiang, Kay J. Park, Robert A. Soslow, Marc Ladanyi, Bob T. Li, Jennifer Mueller, Britta Weigelt, Ahmet Zehir, Michael F. Berger, Nadeem R. Abu-Rustum, Carol Aghajanian, Deborah F. DeLair, David B. Solit, Barry S. Taylor, David M. Hyman
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (23): 5939–5947.
https://doi.org/10.1158/1078-0432.CCR-18-0412
Published: 03 December 2018
View article titled, Clinical Utility of Prospective Molecular Characterization in Advanced Endometrial Cancer
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Includes: Supplementary data