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Mark A. Rubin
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Journal Articles

Framework for the Pathology Workup of Metastatic Castration-Resistant Prostate Cancer Biopsies

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Michael C. Haffner, Michael J. Morris, Chien-Kuang C. Ding, Erolcan Sayar, Rohit Mehra, Brian Robinson, Lawrence D. True, Martin Gleave, Tamara L. Lotan, Rahul Aggarwal, Jiaoti Huang, Massimo Loda, Peter S. Nelson, Mark A. Rubin, Himisha Beltran
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (3): 466–478.
https://doi.org/10.1158/1078-0432.CCR-24-2061
Published: 03 February 2025
View articletitled, Framework for the Pathology Workup of Metastatic Castration-Resistant Prostate Cancer Biopsies
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Includes: Supplementary data
Journal Articles

Pathology: Hub and Integrator of Modern, Multidisciplinary [Precision] Oncology

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The AACR Pathology Task Force, Carolyn C. Compton, Angelo M. De Marzo, Jayanta Debnath, Keith D. Eaton, Kojo Elenitoba-Johnson, Michelangelo Fiorentino, Christopher A. French, Thomas J. Fuchs, Felice Giangaspero, Jiaoti Huang, A. John Iafrate, Michael M. Ittmann, Roy A. Jensen, Annette S. Kim, Massimo Loda, Robin G. Lorenz, Tamara L. Lotan, Anirban Maitra, Gerrit A. Meijer, Richard N. Mitchell, Anil V. Parwani, Francesco Pezzella, Eli Pikarsky, Jorge S. Reis-Filho, Andrea L. Richardson, Mark A. Rubin, Lawrence D. True
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (2): 265–270.
https://doi.org/10.1158/1078-0432.CCR-21-1206
Published: 19 January 2022
View articletitled, Pathology: Hub and Integrator of Modern, Multidisciplinary [Precision] Oncology
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Journal Articles

The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance

Free
Himisha Beltran, Andrew Hruszkewycz, Howard I. Scher, Jeffrey Hildesheim, Jennifer Isaacs, Evan Y. Yu, Kathleen Kelly, Daniel Lin, Adam Dicker, Julia Arnold, Toby Hecht, Max Wicha, Rosalie Sears, David Rowley, Richard White, James L. Gulley, John Lee, Maria Diaz Meco, Eric J. Small, Michael Shen, Karen Knudsen, David W. Goodrich, Tamara Lotan, Amina Zoubeidi, Charles L. Sawyers, Charles M. Rudin, Massimo Loda, Timothy Thompson, Mark A. Rubin, Abdul Tawab-Amiri, William Dahut, Peter S. Nelson
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (23): 6916–6924.
https://doi.org/10.1158/1078-0432.CCR-19-1423
Published: 02 December 2019
View articletitled, The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance
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Includes: Supplementary data
Journal Articles

A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers

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Himisha Beltran, Clara Oromendia, Daniel C. Danila, Bruce Montgomery, Christopher Hoimes, Russell Z. Szmulewitz, Ulka Vaishampayan, Andrew J. Armstrong, Mark Stein, Jacek Pinski, Juan M. Mosquera, Verena Sailer, Rohan Bareja, Alessandro Romanel, Naveen Gumpeni, Andrea Sboner, Etienne Dardenne, Loredana Puca, Davide Prandi, Mark A. Rubin, Howard I. Scher, David S. Rickman, Francesca Demichelis, David M. Nanus, Karla V. Ballman, Scott T. Tagawa
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (1): 43–51.
https://doi.org/10.1158/1078-0432.CCR-18-1912
Published: 03 January 2019
View articletitled, A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers
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Includes: Supplementary data
Journal Articles

SPOP-Mutated/CHD1-Deleted Lethal Prostate Cancer and Abiraterone Sensitivity

Free
Gunther Boysen, Daniel N. Rodrigues, Pasquale Rescigno, George Seed, David Dolling, Ruth Riisnaes, Mateus Crespo, Zafeiris Zafeiriou, Semini Sumanasuriya, Diletta Bianchini, Joanne Hunt, Deirdre Moloney, Raquel Perez-Lopez, Nina Tunariu, Susana Miranda, Inês Figueiredo, Ana Ferreira, Rossitza Christova, Veronica Gil, Sara Aziz, Claudia Bertan, Flavia M. de Oliveira, Mark Atkin, Matthew Clarke, Jane Goodall, Adam Sharp, Theresa MacDonald, Mark A. Rubin, Wei Yuan, Christopher E. Barbieri, Suzanne Carreira, Joaquin Mateo, Johann S. de Bono
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (22): 5585–5593.
https://doi.org/10.1158/1078-0432.CCR-18-0937
Published: 15 November 2018
View articletitled, SPOP-Mutated/CHD1-Deleted Lethal Prostate Cancer and Abiraterone Sensitivity
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Includes: Supplementary data
Journal Articles

Abstract A20: Personalized models to guide precision medicine

Free
Chantal Pauli, Loredana Puca, Benjamin Hopkins, Brooke M. Emerling, Andrea Sboner, Olivier Elemento, Terra J. McNary, Yelena Churakova, Himisha Beltran, Mark A. Rubin
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): A20.
https://doi.org/10.1158/1557-3265.PDX16-A20
Published: 15 August 2016
View articletitled, Abstract A20: Personalized models to guide precision medicine
Journal Articles

Abstract B26: Accelerating prediction of tumor vulnerabilities using next-generation cancer models

Free
Yuen-Yi Tseng, Paula Keskula, Andrew L. Hong, Shubhroz Gill, Jaime H. Cheah, Gregory V. Kryukov, Aviad Tsherniak, Francisca Vazquez, Glenn Cowley, Coyin Oh, Anson Peng, Abeer Sayeed, Rebecca Deasy, Peter Ronning, Philip Kantoff, Levi Garraway, Mark A. Rubin, Calvin Kuo, Sidharth Puram, Adi Gazdar, Filemon S. Dela Cruz, Jr., Adam Bass, Jr., Nikhil Wagle, Keith L. Ligon, Katherine Janeway, David Root, Stuart L. Schreiber, Paul A. Clemons, Aly Shamji, William C. Hahn, Todd R. Golub, Jesse S. Boehm
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): B26.
https://doi.org/10.1158/1557-3265.PDX16-B26
Published: 15 August 2016
View articletitled, Abstract B26: Accelerating prediction of tumor vulnerabilities using next-generation cancer models
Journal Articles

Evidence for Molecular Differences in Prostate Cancer between African American and Caucasian Men

Free
Francesca Khani, Juan Miguel Mosquera, Kyung Park, Mirjam Blattner, Catherine O'Reilly, Theresa Y. MacDonald, Zhengming Chen, Abhishek Srivastava, Ashutosh K. Tewari, Christopher E. Barbieri, Mark A. Rubin, Brian D. Robinson
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (18): 4925–4934.
https://doi.org/10.1158/1078-0432.CCR-13-2265
Published: 14 September 2014
View articletitled, Evidence for Molecular Differences in Prostate Cancer between African American and Caucasian Men
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Includes: Supplementary data
Journal Articles

High-throughput oncogene mutation detection in human cancers by mass spectrometry-based genotyping

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Roman K. Thomas, Alissa C. Baker, Ralph DeBiasi, Whei Feng, Thomas LaFramboise, Meng Wang, Jeffrey C. Lee, Richard Nicoletti, Charles Hatton, Liuda Ziagra, Stacey B. Gabriel, Caroline M. Emery, Heidi Greulich, Mark A. Rubin, Massimo Loda, Jonathan Fletcher, Fred J. Kaye, Kenneth C. Anderson, George D. Demetri, Reinhard Dummer, Stephan N. Wagner, Meenhard Herlyn, William R. Sellers, Matthew L. Meyerson, Levi A. Garraway
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (19_Supplement): A106.
Published: 15 August 2014
View articletitled, High-throughput oncogene mutation detection in human cancers by mass spectrometry-based genotyping
Journal Articles

Aggressive Variants of Castration-Resistant Prostate Cancer

Free
Himisha Beltran, Scott Tomlins, Ana Aparicio, Vivek Arora, David Rickman, Gustavo Ayala, Jiaoti Huang, Lawrence True, Martin E. Gleave, Howard Soule, Christopher Logothetis, Mark A. Rubin
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (11): 2846–2850.
https://doi.org/10.1158/1078-0432.CCR-13-3309
Published: 29 May 2014
View articletitled, Aggressive Variants of Castration-Resistant Prostate Cancer
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Journal Articles

New Strategies in Prostate Cancer: Translating Genomics into the Clinic

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Himisha Beltran, Mark A. Rubin
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (3): 517–523.
https://doi.org/10.1158/1078-0432.CCR-12-1452
Published: 31 January 2013
View articletitled, New Strategies in Prostate Cancer: Translating Genomics into the Clinic
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Journal Articles

Identification of the Transcription Factor Single-Minded Homologue 2 as a Potential Biomarker and Immunotherapy Target in Prostate Cancer

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Mohamed S. Arredouani, Bin Lu, Manoj Bhasin, Miriam Eljanne, Wen Yue, Juan-Miguel Mosquera, Glenn J. Bubley, Vivian Li, Mark A. Rubin, Towia A. Libermann, Martin G. Sanda
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (18): 5794–5802.
https://doi.org/10.1158/1078-0432.CCR-09-0911
Published: 14 September 2009
View articletitled, Identification of the Transcription Factor Single-Minded Homologue 2 as a Potential Biomarker and Immunotherapy Target in Prostate Cancer
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Includes: Supplementary data
Journal Articles

Prevalence of TMPRSS2-ERG Fusion Prostate Cancer among Men Undergoing Prostate Biopsy in the United States

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Juan-Miguel Mosquera, Rohit Mehra, Meredith M. Regan, Sven Perner, Elizabeth M. Genega, Gerri Bueti, Rajal B. Shah, Sandra Gaston, Scott A. Tomlins, John T. Wei, Michael C. Kearney, Laura A. Johnson, Jeffrey M. Tang, Arul M. Chinnaiyan, Mark A. Rubin, Martin G. Sanda
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (14): 4706–4711.
https://doi.org/10.1158/1078-0432.CCR-08-2927
Published: 15 July 2009
View articletitled, Prevalence of TMPRSS2-ERG Fusion Prostate Cancer among Men Undergoing Prostate Biopsy in the United States
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Includes: Supplementary data
Journal Articles

Characterization of TMPRSS2-ERG Fusion High-Grade Prostatic Intraepithelial Neoplasia and Potential Clinical Implications

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Juan-Miguel Mosquera, Sven Perner, Elizabeth M. Genega, Martin Sanda, Matthias D. Hofer, Kirsten D. Mertz, Pamela L. Paris, Jeff Simko, Tarek A. Bismar, Gustavo Ayala, Rajal B. Shah, Massimo Loda, Mark A. Rubin
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (11): 3380–3385.
https://doi.org/10.1158/1078-0432.CCR-07-5194
Published: 02 June 2008
View articletitled, Characterization of TMPRSS2-ERG Fusion High-Grade Prostatic Intraepithelial Neoplasia and Potential Clinical Implications
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Journal Articles

Collagen XXIII Expression Is Associated with Prostate Cancer Recurrence and Distant Metastases

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Jacqueline Banyard, Lere Bao, Matthias D. Hofer, David Zurakowski, Kristin A. Spivey, Adam S. Feldman, Lloyd M. Hutchinson, Rainer Kuefer, Mark A. Rubin, Bruce R. Zetter
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (9): 2634–2642.
https://doi.org/10.1158/1078-0432.CCR-06-2163
Published: 01 May 2007
View articletitled, Collagen XXIII Expression Is Associated with Prostate Cancer Recurrence and Distant Metastases
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Includes: Supplementary data
Journal Articles

Application of Oligonucleotide Microarrays to Assess the Biological Effects of Neoadjuvant Imatinib Mesylate Treatment for Localized Prostate Cancer

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Phillip G. Febbo, Aaron Thorner, Mark A. Rubin, Massimo Loda, Philip W. Kantoff, William K. Oh, Todd Golub, Daniel George
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (1): 152–158.
https://doi.org/10.1158/1078-0432.CCR-05-1652
Published: 05 January 2006
View articletitled, Application of Oligonucleotide Microarrays to Assess the Biological Effects of Neoadjuvant Imatinib Mesylate Treatment for Localized Prostate Cancer
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Includes: Supplementary data
Journal Articles

Translational Crossroads for Biomarkers

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Robert C. Bast, Jr., Hans Lilja, Nicole Urban, David L. Rimm, Herbert Fritsche, Joe Gray, Robert Veltri, George Klee, Andrew Allen, Nam Kim, Steven Gutman, Mark A. Rubin, Andrew Hruszkewycz
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (17): 6103–6108.
https://doi.org/10.1158/1078-0432.CCR-04-2213
Published: 06 September 2005
View articletitled, Translational Crossroads for Biomarkers
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Journal Articles

Identification of Two Molecular Groups of Seminomas by Using Expression and Tissue Microarrays

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Matthias D. Hofer, Tara J. Browne, Le He, Rolf I. Skotheim, Ragnhild A. Lothe, Mark A. Rubin
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (16): 5722–5729.
https://doi.org/10.1158/1078-0432.CCR-05-0533
Published: 22 August 2005
View articletitled, Identification of Two Molecular Groups of Seminomas by Using Expression and Tissue Microarrays
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Journal Articles

Reg IV: A Promising Marker of Hormone Refractory Metastatic Prostate Cancer

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Zhennan Gu, Mark A. Rubin, Yu Yang, Samuel E. Deprimo, Hongjuan Zhao, Steven Horvath, James D. Brooks, Massimo Loda, Robert E. Reiter
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (6): 2237–2243.
https://doi.org/10.1158/1078-0432.CCR-04-0356
Published: 23 March 2005
View articletitled, Reg IV: A Promising Marker of Hormone Refractory Metastatic Prostate Cancer
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Journal Articles

The Role of an 80 kDa Fragment of E-cadherin in the Metastatic Progression of Prostate Cancer

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Rainer Kuefer, Matthias D. Hofer, Juergen E. Gschwend, Kenneth J. Pienta, Martin G. Sanda, Arul M. Chinnaiyan, Mark A. Rubin, Mark L. Day
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (17): 6447–6452.
Published: 24 December 2003
View articletitled, The Role of an 80 kDa Fragment of E-cadherin in the Metastatic Progression of Prostate Cancer
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