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Marianna Zahurak
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Journal Articles

Divergent Clinical and Immunologic Outcomes Based on STK11 Co-mutation Status in Resectable KRAS-Mutant Lung Cancers Following Neoadjuvant Immune Checkpoint Blockade

Samuel Rosner, Sydney Connor, Khaled Sanber, Marianna Zahurak, Tianbei Zhang, Isha Gurumurthy, Zhen Zeng, Brad Presson, Dipika Singh, Roni Rayes, Lavanya Sivapalan, Gavin Pereira, Zhicheng Ji, Rohit Thummalapalli, Joshua E. Reuss, Stephen R. Broderick, David R. Jones, Julie S. Deutsch, Tricia R. Cottrell, Jamie E. Chaft, Jonathan Spicer, Janis Taube, Valsamo Anagnostou, Julie R. Brahmer, Drew M. Pardoll, Hongkai Ji, Patrick M. Forde, Kristen A. Marrone, Kellie N. Smith
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (2): 339–351.
https://doi.org/10.1158/1078-0432.CCR-24-2983
Published: 17 January 2025
View article titled, Divergent Clinical and Immunologic Outcomes Based on <em>STK11</em> Co-mutation Status in Resectable <em>KRAS-</em>Mutant Lung Cancers Following Neoadjuvant Immune Checkpoint Blockade
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Includes: Supplementary data
Journal Articles

Five-Year Clinical Outcomes after Neoadjuvant Nivolumab in Resectable Non–Small Cell Lung Cancer

Samuel Rosner, Joshua E. Reuss, Marianna Zahurak, Jiajia Zhang, Zhen Zeng, Janis Taube, Valsamo Anagnostou, Kellie N. Smith, Joanne Riemer, Peter B. Illei, Stephen R. Broderick, David R. Jones, Suzanne L. Topalian, Drew M. Pardoll, Julie R. Brahmer, Jamie E. Chaft, Patrick M. Forde
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (4): 705–710.
https://doi.org/10.1158/1078-0432.CCR-22-2994
Published: 16 February 2023
View article titled, Five-Year Clinical Outcomes after Neoadjuvant Nivolumab in Resectable Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

A Phase I Trial of a Guadecitabine (SGI-110) and Irinotecan in Metastatic Colorectal Cancer Patients Previously Exposed to Irinotecan

Valerie Lee, Judy Wang, Marianna Zahurak, Elske Gootjes, Henk M. Verheul, Rose Parkinson, Zachary Kerner, Anup Sharma, Gary Rosner, Ana De Jesus-Acosta, Daniel Laheru, Dung T. Le, Aram Oganesian, Ellen Lilly, Thomas Brown, Peter Jones, Stephen Baylin, Nita Ahuja, Nilofer Azad
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (24): 6160–6167.
https://doi.org/10.1158/1078-0432.CCR-18-0421
Published: 13 December 2018
View article titled, A Phase I Trial of a Guadecitabine (SGI-110) and Irinotecan in Metastatic Colorectal Cancer Patients Previously Exposed to Irinotecan
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Includes: Supplementary data
Journal Articles

A Phase I Study of Veliparib (ABT-888) in Combination with Low-Dose Fractionated Whole Abdominal Radiation Therapy in Patients with Advanced Solid Malignancies and Peritoneal Carcinomatosis

Kim A. Reiss, Joseph M. Herman, Marianna Zahurak, Anthony Brade, Laura A. Dawson, Angela Scardina, Caitlin Joffe, Emily Petito, Amy Hacker-Prietz, Robert J. Kinders, Lihua Wang, Alice Chen, Sarah Temkin, Naomi Horiba, Lillian L. Siu, Nilofer S. Azad
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (1): 68–76.
https://doi.org/10.1158/1078-0432.CCR-14-1552
Published: 05 January 2015
View article titled, A Phase I Study of Veliparib (ABT-888) in Combination with Low-Dose Fractionated Whole Abdominal Radiation Therapy in Patients with Advanced Solid Malignancies and Peritoneal Carcinomatosis
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Includes: Supplementary data
Journal Articles

An Epigenetic Marker Panel for Detection of Lung Cancer Using Cell-Free Serum DNA

Shahnaz Begum, Mariana Brait, Santanu Dasgupta, Kimberly L. Ostrow, Marianna Zahurak, André L. Carvalho, Joseph A. Califano, Steven N. Goodman, William H. Westra, Mohammad Obaidul Hoque, David Sidransky
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (13): 4494–4503.
https://doi.org/10.1158/1078-0432.CCR-10-3436
Published: 05 July 2011
View article titled, An Epigenetic Marker Panel for Detection of Lung Cancer Using Cell-Free Serum DNA
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Includes: Supplementary data
Journal Articles

Lenalidomide in Nonmetastatic Biochemically Relapsed Prostate Cancer: Results of a Phase I/II Double-Blinded, Randomized Study

Daniel Keizman, Marianna Zahurak, Victoria Sinibaldi, Michael Carducci, Samuel Denmeade, Charles Drake, Roberto Pili, Emmanuel S. Antonarakis, Susan Hudock, Mario Eisenberger
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (21): 5269–5276.
https://doi.org/10.1158/1078-0432.CCR-10-1928
Published: 31 October 2010
View article titled, Lenalidomide in Nonmetastatic Biochemically Relapsed Prostate Cancer: Results of a Phase I/II Double-Blinded, Randomized Study
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Journal Articles

A Multiple-Loop, Double-Cube Microarray Design Applied to Prostate Cancer Cell Lines with Variable Sensitivity to Histone Deacetylase Inhibitors

Madeleine S.Q. Kortenhorst, Marianna Zahurak, Shabana Shabbeer, Sushant Kachhap, Nathan Galloway, Giovanni Parmigiani, Henk M.W. Verheul, Michael A. Carducci
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (21): 6886–6894.
https://doi.org/10.1158/1078-0432.CCR-08-0119
Published: 03 November 2008
View article titled, A Multiple-Loop, Double-Cube Microarray Design Applied to Prostate Cancer Cell Lines with Variable Sensitivity to Histone Deacetylase Inhibitors
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Journal Articles

A Promoter Methylation Pattern in the N-Methyl-d-Aspartate Receptor 2B Gene Predicts Poor Prognosis in Esophageal Squamous Cell Carcinoma

Myoung Sook Kim, Keishi Yamashita, Young Kwang Chae, Yutaka Tokumaru, Xiaofei Chang, Marianna Zahurak, Motonobu Osada, Hannah Lui Park, Alice Chuang, Joseph A. Califano, David Sidransky
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (22): 6658–6665.
https://doi.org/10.1158/1078-0432.CCR-07-1178
Published: 15 November 2007
View article titled, A Promoter Methylation Pattern in the <em>N</em>-Methyl-<sc>d</sc>-Aspartate Receptor 2B Gene Predicts Poor Prognosis in Esophageal Squamous Cell Carcinoma
Open the PDF for A Promoter Methylation Pattern in the <em>N</em>-Methyl-<sc>d</sc>-Aspartate Receptor 2B Gene Predicts Poor Prognosis in Esophageal Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Decreased Mitochondrial DNA Content in Posttreatment Salivary Rinses from Head and Neck Cancer Patients

Wei-Wen Jiang, Eli Rosenbaum, Elizabeth Mambo, Marianna Zahurak, Brett Masayesva, Andre Lopes Carvalho, Shaoyu Zhou, William H. Westra, Anthony J. Alberg, David Sidransky, Wayne Koch, Joseph A. Califano
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (5): 1564–1569.
https://doi.org/10.1158/1078-0432.CCR-05-1471
Published: 06 March 2006
View article titled, Decreased Mitochondrial DNA Content in Posttreatment Salivary Rinses from Head and Neck Cancer Patients
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Journal Articles

Promoter Hypermethylation as an Independent Prognostic Factor for Relapse in Patients with Prostate Cancer Following Radical Prostatectomy

Eli Rosenbaum, Mohammad Obaidul Hoque, Yoram Cohen, Marianna Zahurak, Mario A. Eisenberger, Jonathan I. Epstein, Alan W. Partin, David Sidransky
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (23): 8321–8325.
https://doi.org/10.1158/1078-0432.CCR-05-1183
Published: 01 December 2005
View article titled, Promoter Hypermethylation as an Independent Prognostic Factor for Relapse in Patients with Prostate Cancer Following Radical Prostatectomy
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Journal Articles

Tissue Distribution of Human Papillomavirus 16 DNA Integration in Patients with Tonsillar Carcinoma

Shahnaz Begum, Dengfeng Cao, Maura Gillison, Marianna Zahurak, William H. Westra
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (16): 5694–5699.
https://doi.org/10.1158/1078-0432.CCR-05-0587
Published: 22 August 2005
View article titled, Tissue Distribution of Human Papillomavirus 16 DNA Integration in Patients with Tonsillar Carcinoma
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Journal Articles

Marimastat in the Treatment of Patients with Biochemically Relapsed Prostate Cancer: A Prospective Randomized, Double-Blind, Phase I/II Trial

Eli Rosenbaum, Marianna Zahurak, Victoria Sinibaldi, Michael A. Carducci, Roberto Pili, Menachem Laufer, Theodore L. DeWeese, Mario A. Eisenberger
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (12): 4437–4443.
https://doi.org/10.1158/1078-0432.CCR-04-2252
Published: 15 June 2005
View article titled, Marimastat in the Treatment of Patients with Biochemically Relapsed Prostate Cancer: A Prospective Randomized, Double-Blind, Phase I/II Trial
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Journal Articles

Increased Mitochondrial DNA Content in Saliva Associated with Head and Neck Cancer

Wei-Wen Jiang, Brett Masayesva, Marianna Zahurak, Andre Lopes Carvalho, Eli Rosenbaum, Elizabeth Mambo, Shaoyu Zhou, Khalid Minhas, Nicole Benoit, William H. Westra, Anthony Alberg, David Sidransky, Wayne Koch, Joseph Califano
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (7): 2486–2491.
https://doi.org/10.1158/1078-0432.CCR-04-2147
Published: 06 April 2005
View article titled, Increased Mitochondrial DNA Content in Saliva Associated with Head and Neck Cancer
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Journal Articles

MAP2K4/MKK4 Expression in Pancreatic Cancer: Genetic Validation of Immunohistochemistry and Relationship to Disease Course

Wei Xin, Ki J. Yun, Francesca Ricci, Marianna Zahurak, Wanglong Qiu, Gloria H. Su, Charles J. Yeo, Ralph H. Hruban, Scott E. Kern, Christine A. Iacobuzio-Donahue
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (24): 8516–8520.
https://doi.org/10.1158/1078-0432.CCR-04-0885
Published: 28 December 2004
View article titled, MAP2K4/MKK4 Expression in Pancreatic Cancer: <subtitle>Genetic Validation of Immunohistochemistry and Relationship to Disease Course</subtitle>
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Journal Articles

Human Telomerase Reverse Transcriptase Gene Expression and the Surgical Management of Suspicious Thyroid Tumors

Christopher B. Umbricht, George T. Conrad, Douglas P. Clark, William H. Westra, Dañelle C. Smith, Marianna Zahurak, Motoyasu Saji, Robert C. Smallridge, Steven Goodman, Martha A. Zeiger
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (17): 5762–5768.
https://doi.org/10.1158/1078-0432.CCR-03-0389
Published: 08 September 2004
View article titled, Human Telomerase Reverse Transcriptase Gene Expression and the Surgical Management of Suspicious Thyroid Tumors
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Journal Articles

A Transcriptional Progression Model for Head and Neck Cancer

Patrick K. Ha, Nicole E. Benoit, Robert Yochem, James Sciubba, Marianna Zahurak, David Sidransky, Jonathan Pevsner, William H. Westra, Joseph Califano
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (8): 3058–3064.
Published: 11 August 2003
View article titled, A Transcriptional Progression Model for Head and Neck Cancer
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Journal Articles

LKB1 Protein Expression in the Evolution of Glandular Neoplasia of the Lung

Hassan Ghaffar, Fikret Sahin, Montserrat Sanchez-Cepedes, Gloria H. Su, Marianna Zahurak, David Sidransky, William H. Westra
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (8): 2998–3003.
Published: 11 August 2003
View article titled, LKB1 Protein Expression in the Evolution of Glandular Neoplasia of the Lung
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Journal Articles

Mitochondrial C-tract Alteration in Premalignant Lesions of the Head and Neck: A Marker for Progression and Clonal Proliferation

Patrick K. Ha, Betty C. Tong, William H. Westra, Montserrat Sanchez-Cespedes, Paola Parrella, Marianna Zahurak, David Sidransky, Joseph A Califano
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (7): 2260–2265.
Published: 01 July 2002
View article titled, Mitochondrial C-tract Alteration in Premalignant Lesions of the Head and Neck: <subtitle>A Marker for Progression and Clonal Proliferation</subtitle>
Open the PDF for Mitochondrial C-tract Alteration in Premalignant Lesions of the Head and Neck: <subtitle>A Marker for Progression and Clonal Proliferation</subtitle> in another window