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Margaretha Rudas
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Journal Articles

Abstract PS3-03: Vaccination with MUC-1-targeting tecemotide improves Survival of patients receiving neo-adjuvant chemotherapy for early breast cancer: Results from the Prospective Randomized ABCSG 34 Trial

Free
Christian F. Singer, Dominik Hlauschek, Georg Pfeiler, Daniel Egle, Rupert Bartsch, Christoph Suppan, Angelika Pichler, Edgar Petru, Richard Greil, Margaretha Rudas, Michael Seifert, Gregor Huber, Andreas Petzer, Florian Fitzal, Zsuzsanna Bago-Horvath, Martin Filipits, Lidija Soelkner, Christian Fesl, Michael Gnant
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (12_Supplement): PS3-03.
https://doi.org/10.1158/1557-3265.SABCS24-PS3-03
Published: 13 June 2025
View articletitled, Abstract PS3-03: Vaccination with MUC-1-targeting tecemotide improves Survival of patients receiving neo-adjuvant chemotherapy for early breast cancer: Results from the Prospective Randomized ABCSG 34 Trial
Journal Articles

Abstract P2-01-24: Immune activation of tumor cells and microenvironment as assessed by PD-L1 expression and interferon gamma signaling predict long term disease-free and overall survival: Results of the prospective randomized neoadjuvant ABCSG 34 trial

Free
Ulrike M. Heber, Dominik Hlauschek, Christian F. Singer, Daniel Egle, Richard Greil, Ruth Helfgott, Gregor Huber, Elisabeth Müller-Holzner, Cornelia Hauser-Kronberger, Margaretha Rudas, Georg Pfeiler, Rupert Bartsch, Sigurd Lax, Martin Filipits, Gabriel Rinnerthaler, Michael Gnant, Zsuzsanna Bago-Horvath
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (12_Supplement): P2-01-24.
https://doi.org/10.1158/1557-3265.SABCS24-P2-01-24
Published: 13 June 2025
View articletitled, Abstract P2-01-24: Immune activation of tumor cells and microenvironment as assessed by PD-L1 expression and interferon gamma signaling predict long term disease-free and overall survival: Results of the prospective randomized neoadjuvant ABCSG 34 trial
Journal Articles

Estrogen Receptor Alpha Gene Amplification Is an Independent Predictor of Long-Term Outcome in Postmenopausal Patients with Endocrine-Responsive Early Breast Cancer

Open Access
Christian F. Singer, for the ABCSG, Frederik Holst, Stefan Steurer, Eike C. Burandt, Sigurd F. Lax, Raimund Jakesz, Margaretha Rudas, Herbert Stöger, Richard Greil, for the ABCSG, Guido Sauter, Martin Filipits, for the ABCSG, Ronald Simon, Michael Gnant, for the ABCSG
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18): 4112–4120.
https://doi.org/10.1158/1078-0432.CCR-21-4328
Published: 15 September 2022
View articletitled, Estrogen Receptor Alpha Gene Amplification Is an Independent Predictor of Long-Term Outcome in Postmenopausal Patients with Endocrine-Responsive Early Breast Cancer
Open the PDF for Estrogen Receptor Alpha Gene Amplification Is an Independent Predictor of Long-Term Outcome in Postmenopausal Patients with Endocrine-Responsive Early Breast Cancer in another window
Journal Articles

Persistence of ctDNA in Patients with Breast Cancer During Neoadjuvant Treatment Is a Significant Predictor of Poor Tumor Response

Open Access
Qing Zhou, Simon P. Gampenrieder, Sophie Frantal, Gabriel Rinnerthaler, Christian F. Singer, Daniel Egle, Georg Pfeiler, Rupert Bartsch, Viktor Wette, Angelika Pichler, Edgar Petru, Peter C. Dubsky, Zsuzsanna Bago-Horvath, Christian Fesl, Margaretha Rudas, Anders Ståhlberg, Ricarda Graf, Sabrina Weber, Nadia Dandachi, Martin Filipits, Michael Gnant, Marija Balic, Ellen Heitzer
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (4): 697–707.
https://doi.org/10.1158/1078-0432.CCR-21-3231
Published: 15 February 2022
View articletitled, Persistence of ctDNA in Patients with Breast Cancer During Neoadjuvant Treatment Is a Significant Predictor of Poor Tumor Response
Open the PDF for Persistence of ctDNA in Patients with Breast Cancer During Neoadjuvant Treatment Is a Significant Predictor of Poor Tumor Response in another window
Includes: Supplementary data
Journal Articles

The OncoMasTR Test Predicts Distant Recurrence in Estrogen Receptor–Positive, HER2-Negative Early-Stage Breast Cancer: A Validation Study in ABCSG Trial 8

Available to Purchase
Martin Filipits, Margaretha Rudas, Verena Kainz, Christian F. Singer, Florian Fitzal, Zsuzsanna Bago-Horvath, Richard Greil, Marija Balic, Peter Regitnig, Stefan Halper, Wolfgang Hulla, Daniel Egle, Stephen Barron, Tony Loughman, Des O'Leary, William M. Gallagher, Dominik Hlauschek, Michael Gnant, Peter Dubsky
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (21): 5931–5938.
https://doi.org/10.1158/1078-0432.CCR-21-1023
Published: 01 November 2021
View articletitled, The OncoMasTR Test Predicts Distant Recurrence in Estrogen Receptor–Positive, HER2-Negative Early-Stage Breast Cancer: A Validation Study in ABCSG Trial 8
Open the PDF for The OncoMasTR Test Predicts Distant Recurrence in Estrogen Receptor–Positive, HER2-Negative Early-Stage Breast Cancer: A Validation Study in ABCSG Trial 8 in another window
Includes: Supplementary data
Journal Articles

Predictive Value of Molecular Subtypes in Premenopausal Women with Hormone Receptor–positive Early Breast Cancer: Results from the ABCSG Trial 5

Available to Purchase
Zsuzsanna Bago-Horvath, Margaretha Rudas, Christian F. Singer, Richard Greil, Marija Balic, Sigurd F. Lax, Werner Kwasny, Wolfgang Hulla, Michael Gnant, Martin Filipits
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (21): 5682–5688.
https://doi.org/10.1158/1078-0432.CCR-20-0673
Published: 02 November 2020
View articletitled, Predictive Value of Molecular Subtypes in Premenopausal Women with Hormone Receptor–positive Early Breast Cancer: Results from the ABCSG Trial 5
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Journal Articles

Prognostic Value of EndoPredict in Women with Hormone Receptor–Positive, HER2-Negative Invasive Lobular Breast Cancer

Available to Purchase
Ivana Sestak, Martin Filipits, Richard Buus, Margaretha Rudas, Marija Balic, Michael Knauer, Ralf Kronenwett, Florian Fitzal, Jack Cuzick, Michael Gnant, Richard Greil, Mitch Dowsett, Peter Dubsky
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (17): 4682–4687.
https://doi.org/10.1158/1078-0432.CCR-20-0260
Published: 01 September 2020
View articletitled, Prognostic Value of EndoPredict in Women with Hormone Receptor–Positive, HER2-Negative Invasive Lobular Breast Cancer
Open the PDF for Prognostic Value of EndoPredict in Women with Hormone Receptor–Positive, HER2-Negative Invasive Lobular Breast Cancer in another window
Journal Articles

Prediction of Distant Recurrence Using EndoPredict Among Women with ER+, HER2− Node-Positive and Node-Negative Breast Cancer Treated with Endocrine Therapy Only

Free
Martin Filipits, Peter Dubsky, Margaretha Rudas, Richard Greil, Marija Balic, Zsuzsanna Bago-Horvath, Christian F. Singer, Dominik Hlauschek, Krystal Brown, Ryan Bernhisel, Ralf Kronenwett, Johnathan M. Lancaster, Florian Fitzal, Michael Gnant
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (13): 3865–3872.
https://doi.org/10.1158/1078-0432.CCR-19-0376
Published: 01 July 2019
View articletitled, Prediction of Distant Recurrence Using EndoPredict Among Women with ER+, HER2− Node-Positive and Node-Negative Breast Cancer Treated with Endocrine Therapy Only
Open the PDF for Prediction of Distant Recurrence Using EndoPredict Among Women with ER+, HER2− Node-Positive and Node-Negative Breast Cancer Treated with Endocrine Therapy Only in another window
Includes: Supplementary data
Journal Articles

Continued Endocrine Therapy Is Associated with Improved Survival in Patients with Breast Cancer Brain Metastases

Free
Elisabeth S. Bergen, Anna S. Berghoff, Mela Medjedovic, Margaretha Rudas, Florian Fitzal, Zsuzsanna Bago-Horvath, Karin Dieckmann, Robert M. Mader, Ruth Exner, Michael Gnant, Christoph C. Zielinski, Guenther G. Steger, Matthias Preusser, Rupert Bartsch
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (9): 2737–2744.
https://doi.org/10.1158/1078-0432.CCR-18-1968
Published: 01 May 2019
View articletitled, Continued Endocrine Therapy Is Associated with Improved Survival in Patients with Breast Cancer Brain Metastases
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Includes: Supplementary data
Journal Articles

Pathological Complete Response to Neoadjuvant Trastuzumab Is Dependent on HER2/CEP17 Ratio in HER2-Amplified Early Breast Cancer

Free
Christian F. Singer, Yen Y. Tan, Florian Fitzal, Guenther G. Steger, Daniel Egle, Angelika Reiner, Margaretha Rudas, Farid Moinfar, Christine Gruber, Edgar Petru, Rupert Bartsch, Kristina A. Tendl, David Fuchs, Michael Seifert, Ruth Exner, Marija Balic, Zsuzsanna Bago-Horvath, Martin Filipits, Michael Gnant
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (14): 3676–3683.
https://doi.org/10.1158/1078-0432.CCR-16-2373
Published: 13 July 2017
View articletitled, Pathological Complete Response to Neoadjuvant Trastuzumab Is Dependent on HER2/CEP17 Ratio in HER2-Amplified Early Breast Cancer
Open the PDF for Pathological Complete Response to Neoadjuvant Trastuzumab Is Dependent on HER2/CEP17 Ratio in HER2-Amplified Early Breast Cancer in another window
Includes: Supplementary data
Journal Articles

The PAM50 Risk-of-Recurrence Score Predicts Risk for Late Distant Recurrence after Endocrine Therapy in Postmenopausal Women with Endocrine-Responsive Early Breast Cancer

Free
Martin Filipits, Torsten O. Nielsen, Margaretha Rudas, Richard Greil, Herbert Stöger, Raimund Jakesz, Zsuzsanna Bago-Horvath, Otto Dietze, Peter Regitnig, Christine Gruber-Rossipal, Elisabeth Müller-Holzner, Christian F. Singer, Brigitte Mlineritsch, Peter Dubsky, Thomas Bauernhofer, Michael Hubalek, Michael Knauer, Harald Trapl, Christian Fesl, Carl Schaper, Sean Ferree, Shuzhen Liu, J. Wayne Cowens, Michael Gnant, for the Austrian Breast and Colorectal Cancer Study Group
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (5): 1298–1305.
https://doi.org/10.1158/1078-0432.CCR-13-1845
Published: 02 March 2014
View articletitled, The PAM50 Risk-of-Recurrence Score Predicts Risk for Late Distant Recurrence after Endocrine Therapy in Postmenopausal Women with Endocrine-Responsive Early Breast Cancer
Open the PDF for The PAM50 Risk-of-Recurrence Score Predicts Risk for Late Distant Recurrence after Endocrine Therapy in Postmenopausal Women with Endocrine-Responsive Early Breast Cancer in another window
Includes: Supplementary data
Journal Articles

CYP2D6 Metabolism and Patient Outcome in the Austrian Breast and Colorectal Cancer Study Group Trial (ABCSG) 8

Free
Matthew P. Goetz, Vera J. Suman, Tanya L. Hoskin, Michael Gnant, Martin Filipits, Stephanie L. Safgren, Mary Kuffel, Raimund Jakesz, Margaretha Rudas, Richard Greil, Otto Dietze, Alois Lang, Felix Offner, Carol A. Reynolds, Richard M. Weinshilboum, Matthew M. Ames, James N. Ingle
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (2): 500–507.
https://doi.org/10.1158/1078-0432.CCR-12-2153
Published: 16 January 2013
View articletitled, CYP2D6 Metabolism and Patient Outcome in the Austrian Breast and Colorectal Cancer Study Group Trial (ABCSG) 8
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Journal Articles

Adjuvant Sequencing of Tamoxifen and Anastrozole Is Superior to Tamoxifen Alone in Postmenopausal Women with Low Proliferating Breast Cancer

Free
Zsuzsanna Bago-Horvath, Margaretha Rudas, Peter Dubsky, Raimund Jakesz, Christian F. Singer, Ralf Kemmerling, Richard Greil, Andrea Jelen, Gerhard Böhm, Zerina Jasarevic, Anton Haid, Christine Gruber, Sabine Pöstlberger, Martin Filipits, Michael Gnant
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (24): 7828–7834.
https://doi.org/10.1158/1078-0432.CCR-11-1846
Published: 18 December 2011
View articletitled, Adjuvant Sequencing of Tamoxifen and Anastrozole Is Superior to Tamoxifen Alone in Postmenopausal Women with Low Proliferating Breast Cancer
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Journal Articles

A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk Factors

Free
Martin Filipits, Margaretha Rudas, Raimund Jakesz, Peter Dubsky, Florian Fitzal, Christian F. Singer, Otto Dietze, Richard Greil, Andrea Jelen, Paul Sevelda, Christa Freibauer, Volkmar Müller, Fritz Jänicke, Marcus Schmidt, Heinz Kölbl, Achim Rody, Manfred Kaufmann, Werner Schroth, Hiltrud Brauch, Matthias Schwab, Peter Fritz, Karsten E. Weber, Inke S. Feder, Guido Hennig, Ralf Kronenwett, Mathias Gehrmann, Michael Gnant
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (18): 6012–6020.
https://doi.org/10.1158/1078-0432.CCR-11-0926
Published: 14 September 2011
View articletitled, A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk Factors
Open the PDF for A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk Factors in another window
Includes: Supplementary data
Journal Articles

Low p27 Expression Predicts Early Relapse and Death in Postmenopausal Hormone Receptor–Positive Breast Cancer Patients Receiving Adjuvant Tamoxifen Therapy

Free
Martin Filipits, Margaretha Rudas, Harald Heinzl, Raimund Jakesz, Ernst Kubista, Sigurd Lax, Walter Schippinger, Otto Dietze, Richard Greil, Wolfgang Stiglbauer, Werner Kwasny, Alexander Nader, Michael Stierer, Michael F.X. Gnant, for the Austrian Breast and Colorectal Cancer Study Group
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (18): 5888–5894.
https://doi.org/10.1158/1078-0432.CCR-09-0728
Published: 14 September 2009
View articletitled, Low p27 Expression Predicts Early Relapse and Death in Postmenopausal Hormone Receptor–Positive Breast Cancer Patients Receiving Adjuvant Tamoxifen Therapy
Open the PDF for Low p27 Expression Predicts Early Relapse and Death in Postmenopausal Hormone Receptor–Positive Breast Cancer Patients Receiving Adjuvant Tamoxifen Therapy in another window
Journal Articles

Cyclin D1 Expression in Breast Cancer Patients Receiving Adjuvant Tamoxifen-Based Therapy

Free
Margaretha Rudas, Martina Lehnert, Anh Huynh, Raimund Jakesz, Christian Singer, Sigurd Lax, Walter Schippinger, Otto Dietze, Richard Greil, Wolfgang Stiglbauer, Werner Kwasny, Renate Grill, Michael Stierer, Michael F.X. Gnant, Martin Filipits, for the Austrian Breast and Colorectal Cancer Study Group
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (6): 1767–1774.
https://doi.org/10.1158/1078-0432.CCR-07-4122
Published: 17 March 2008
View articletitled, Cyclin D1 Expression in Breast Cancer Patients Receiving Adjuvant Tamoxifen-Based Therapy
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Journal Articles

Her2 and Progesterone Receptor Status Are Not Predictive of Response to Fulvestrant Treatment

Free
Rupert Bartsch, Catharina Wenzel, Gabriela Altorjai, Ursula Pluschnig, Robert M. Mader, Michael Gnant, Raimund Jakesz, Margaretha Rudas, Christoph C. Zielinski, Guenther G. Steger
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (15): 4435–4439.
https://doi.org/10.1158/1078-0432.CCR-06-3050
Published: 01 August 2007
View articletitled, Her2 and Progesterone Receptor Status Are Not Predictive of Response to Fulvestrant Treatment
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