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Marcel Kool
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Journal Articles

Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study

Alberto Delaidelli, Christopher Dunham, Mariarita Santi, Gian Luca Negri, Joanna Triscott, Olga Zheludkova, Andrey Golanov, Marina Ryzhova, Konstantin Okonechnikov, Daniel Schrimpf, Damian Stichel, David W. Ellison, Andreas von Deimling, Marcel Kool, Stefan M. Pfister, Vijay Ramaswamy, Andrey Korshunov, Michael D. Taylor, Poul H. Sorensen
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (1): 116–128.
https://doi.org/10.1158/1078-0432.CCR-21-2057
Published: 05 January 2022
View article titled, Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study
Open the PDF for Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study in another window
Includes: Supplementary data
Journal Articles

Relevance of Molecular Groups in Children with Newly Diagnosed Atypical Teratoid Rhabdoid Tumor: Results from Prospective St. Jude Multi-institutional Trials

Santhosh A. Upadhyaya, Giles W. Robinson, Arzu Onar-Thomas, Brent A. Orr, Pascal Johann, Gang Wu, Catherine A. Billups, Ruth G. Tatevossian, Sandeep Kumar Dhanda, Ashok Srinivasan, Alberto Broniscer, Ibrahim Qaddoumi, Anna Vinitsky, Gregory T. Armstrong, Anne E. Bendel, Tim Hassall, Sonia Partap, Paul G. Fisher, John R. Crawford, Murali Chintagumpala, Eric Bouffet, Sridharan Gururangan, Roya Mostafavi, Robert P. Sanders, Paul Klimo, Jr, Zoltan Patay, Daniel J. Indelicato, Kim E. Nichols, Frederick A. Boop, Thomas E. Merchant, Marcel Kool, David W. Ellison, Amar Gajjar
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (10): 2879–2889.
https://doi.org/10.1158/1078-0432.CCR-20-4731
Published: 15 May 2021
View article titled, Relevance of Molecular Groups in Children with Newly Diagnosed Atypical Teratoid Rhabdoid Tumor: Results from Prospective St. Jude Multi-institutional Trials
Open the PDF for Relevance of Molecular Groups in Children with Newly Diagnosed Atypical Teratoid Rhabdoid Tumor: Results from Prospective St. Jude Multi-institutional Trials in another window
Includes: Supplementary data
Journal Articles

Delta-24-RGD, an Oncolytic Adenovirus, Increases Survival and Promotes Proinflammatory Immune Landscape Remodeling in Models of AT/RT and CNS-PNET

Marc Garcia-Moure, Marisol Gonzalez-Huarriz, Sara Labiano, Elizabeth Guruceaga, Eva Bandres, Marta Zalacain, Lucia Marrodan, Carlos de Andrea, Maria Villalba, Naiara Martinez-Velez, Virginia Laspidea, Montse Puigdelloses, Jaime Gallego Perez-Larraya, Ignacio Iñigo-Marco, Renata Stripecke, Jennifer A. Chan, Eric H. Raabe, Marcel Kool, Candelaria Gomez-Manzano, Juan Fueyo, Ana Patiño-García, Marta M. Alonso
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (6): 1807–1820.
https://doi.org/10.1158/1078-0432.CCR-20-3313
Published: 15 March 2021
View article titled, Delta-24-RGD, an Oncolytic Adenovirus, Increases Survival and Promotes Proinflammatory Immune Landscape Remodeling in Models of AT/RT and CNS-PNET
Open the PDF for Delta-24-RGD, an Oncolytic Adenovirus, Increases Survival and Promotes Proinflammatory Immune Landscape Remodeling in Models of AT/RT and CNS-PNET in another window
Includes: Supplementary data
Journal Articles

The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

Juliane L. Buhl, Florian Selt, Thomas Hielscher, Romain Guiho, Jonas Ecker, Felix Sahm, Johannes Ridinger, Dennis Riehl, Diren Usta, Britta Ismer, Alexander C. Sommerkamp, J.P. Martinez-Barbera, Annika K. Wefers, Marc Remke, Daniel Picard, Stefan Pusch, Jan Gronych, Ina Oehme, Cornelis M. van Tilburg, Marcel Kool, Daniela Kuhn, David Capper, Andreas von Deimling, Martin U. Schuhmann, Christel Herold-Mende, Andrey Korshunov, Tilman Brummer, Stefan M. Pfister, David T.W. Jones, Olaf Witt, Till Milde
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1851–1866.
https://doi.org/10.1158/1078-0432.CCR-18-1965
Published: 15 March 2019
View article titled, The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma
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Includes: Supplementary data
Journal Articles

Abstract A25: Establishment of orthotopic patient-derived xenograft models of pediatric brain tumors – the Heidelberg experience

Norman L. Mack, Sebastian Brabetz, Florian Selt, Xanthopolous Christina, David Sumerauer, Heidi Bächli, Arnulf Pekrun, Martin U. Schuhmann, Stefan M. Pfister, Olaf Witt, Till Milde, Marcel Kool
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): A25.
https://doi.org/10.1158/1557-3265.PDX16-A25
Published: 15 August 2016
View article titled, Abstract A25: Establishment of orthotopic patient-derived xenograft models of pediatric brain tumors – the Heidelberg experience
Journal Articles

Abstract A07: Molecular characterization of patient-derived xenograft models of pediatric brain tumors

Sebastian Brabetz, Huriye Seker-Cin, Susanne N. Gröbner, Norman L. Mack, Volker Hovestadt, David T. W. Jones, Till Milde, Madison T. Wise, Jessica M. Rusert, Kyle Pedro, Karina Bloom, Xiao-Nan Li, Robert J. Wechsler-Reya, James M. Olson, Stefan M. Pfister, Marcel Kool
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): A07.
https://doi.org/10.1158/1557-3265.PDX16-A07
Published: 15 August 2016
View article titled, Abstract A07: Molecular characterization of patient-derived xenograft models of pediatric brain tumors
Journal Articles

Abstract B37: Chemi-genomic analysis of patient-derived xenografts to identify personalized therapies for medulloblastoma

Jessica M. Rusert, Alexandra Garancher, Yoko T. Udaka, Sebastian Brabetz, Lourdes A. Esparza, Huriye Seker-Cin, Lin Qi, Mari Kogiso, Simone Schubert, Till Milde, Yoon-Jae Cho, Xiao-Nan Li, James M. Olson, John R. Crawford, Michael L. Levy, Marcel Kool, Stefan M. Pfister, Robert J. Wechsler-Reya
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): B37.
https://doi.org/10.1158/1557-3265.PDX16-B37
Published: 15 August 2016
View article titled, Abstract B37: Chemi-genomic analysis of patient-derived xenografts to identify personalized therapies for medulloblastoma
Journal Articles

PID1 (NYGGF4), a New Growth-Inhibitory Gene in Embryonal Brain Tumors and Gliomas

Anat Erdreich-Epstein, Nathan Robison, Xiuhai Ren, Hong Zhou, Jingying Xu, Tom B. Davidson, Mathew Schur, Floyd H. Gilles, Lingyun Ji, Jemily Malvar, Gregory M. Shackleford, Ashley S. Margol, Mark D. Krieger, Alexander R. Judkins, David T.W. Jones, Stefan M. Pfister, Marcel Kool, Richard Sposto, Shahab Asgharazadeh
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2014) 20 (4): 827–836.
https://doi.org/10.1158/1078-0432.CCR-13-2053
Published: 16 February 2014
View article titled, <em>PID1</em> (<em>NYGGF4</em>), a New Growth-Inhibitory Gene in Embryonal Brain Tumors and Gliomas
Open the PDF for <em>PID1</em> (<em>NYGGF4</em>), a New Growth-Inhibitory Gene in Embryonal Brain Tumors and Gliomas in another window
Includes: Supplementary data
Journal Articles

EZH2-Regulated DAB2IP Is a Medulloblastoma Tumor Suppressor and a Positive Marker for Survival

Michiel Smits, Sjoerd van Rijn, Esther Hulleman, Dennis Biesmans, Dannis G. van Vuurden, Marcel Kool, Christine Haberler, Eleonora Aronica, W. Peter Vandertop, David P. Noske, Thomas Würdinger
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (15): 4048–4058.
https://doi.org/10.1158/1078-0432.CCR-12-0399
Published: 30 July 2012
View article titled, EZH2-Regulated DAB2IP Is a Medulloblastoma Tumor Suppressor and a Positive Marker for Survival
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Includes: Supplementary data
Journal Articles

Molecular Risk Stratification of Medulloblastoma Patients Based on Immunohistochemical Analysis of MYC, LDHB, and CCNB1 Expression

Talitha de Haas, Nancy Hasselt, Dirk Troost, Huib Caron, Mara Popovic, Lorna Zadravec-Zaletel, Wieslawa Grajkowska, Marta Perek, Maria-Chiara Osterheld, David Ellison, Frank Baas, Rogier Versteeg, Marcel Kool
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (13): 4154–4160.
https://doi.org/10.1158/1078-0432.CCR-07-4159
Published: 01 July 2008
View article titled, Molecular Risk Stratification of Medulloblastoma Patients Based on Immunohistochemical Analysis of MYC, LDHB, and CCNB1 Expression
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Includes: Supplementary data
Journal Articles

Drug Resistance-associated Markers P-Glycoprotein, Multidrug Resistance-associated Protein 1, Multidrug Resistance-associated Protein 2, and Lung Resistance Protein as Prognostic Factors in Ovarian Carcinoma

Henriette J. G. Arts, Dionyssios Katsaros, Elisabeth G. E. de Vries, Marco Massobrio, Franco Genta, Silvio Danese, Riccardo Arisio, Rick J. Scheper, Marcel Kool, George L. Scheffer, Pax H. B. Willemse, Ate G. J. van der Zee, Albert J. H. Suurmeijer
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (10): 2798–2805.
Published: 01 October 1999
View article titled, Drug Resistance-associated Markers P-Glycoprotein, Multidrug Resistance-associated Protein 1, Multidrug Resistance-associated Protein 2, and Lung Resistance Protein as Prognostic Factors in Ovarian Carcinoma
Open the PDF for Drug Resistance-associated Markers P-Glycoprotein, Multidrug Resistance-associated Protein 1, Multidrug Resistance-associated Protein 2, and Lung Resistance Protein as Prognostic Factors in Ovarian Carcinoma in another window