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Journal Articles

NPY Methylated ctDNA is a Promising Biomarker for Treatment Response Monitoring in Metastatic Colorectal Cancer

Katleen Janssens, Greetje Vanhoutte, Willem Lybaert, Wim Demey, Jochen Decaestecker, Koen Hendrickx, Hassan Rezaei Kalantari, Karen Zwaenepoel, Patrick Pauwels, Erik Fransen, Ken Op de Beeck, Guy Van Camp, Christian Rolfo, Marc Peeters
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (9): 1741–1750.
https://doi.org/10.1158/1078-0432.CCR-22-1500
Published: 01 May 2023
View article titled, <em>NPY</em> Methylated ctDNA is a Promising Biomarker for Treatment Response Monitoring in Metastatic Colorectal Cancer
Open the PDF for <em>NPY</em> Methylated ctDNA is a Promising Biomarker for Treatment Response Monitoring in Metastatic Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Humoral and Cellular Immune Responses against SARS-CoV-2 after Third Dose BNT162b2 following Double-Dose Vaccination with BNT162b2 versus ChAdOx1 in Patients with Cancer

Yana Debie, Jonas R.M. Van Audenaerde, Timon Vandamme, Lieselot Croes, Laure-Anne Teuwen, Lise Verbruggen, Greetje Vanhoutte, Elly Marcq, Lisa Verheggen, Debbie Le Blon, Bart Peeters, Maria E. Goossens, Pieter Pannus, Kevin K. Ariën, Sébastien Anguille, Annelies Janssens, Hans Prenen, Evelien L.J. Smits, Christof Vulsteke, Eva Lion, Marc Peeters, Peter A. van Dam
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (3): 635–646.
https://doi.org/10.1158/1078-0432.CCR-22-2185
Published: 01 February 2023
View article titled, Humoral and Cellular Immune Responses against SARS-CoV-2 after Third Dose BNT162b2 following Double-Dose Vaccination with BNT162b2 versus ChAdOx1 in Patients with Cancer
Open the PDF for Humoral and Cellular Immune Responses against SARS-CoV-2 after Third Dose BNT162b2 following Double-Dose Vaccination with BNT162b2 versus ChAdOx1 in Patients with Cancer in another window
Includes: Supplementary data
Journal Articles

Longitudinal Copy-Number Alteration Analysis in Plasma Cell-Free DNA of Neuroendocrine Neoplasms is a Novel Specific Biomarker for Diagnosis, Prognosis, and Follow-up

Gitta Boons, Timon Vandamme, Laura Mariën, Willem Lybaert, Geert Roeyen, Tim Rondou, Konstantinos Papadimitriou, Katrien Janssens, Bart Op de Beeck, Marc Simoens, Wim Demey, Isabel Dero, Guy Van Camp, Marc Peeters, Ken Op de Beeck
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (2): 338–349.
https://doi.org/10.1158/1078-0432.CCR-21-2291
Published: 15 January 2022
View article titled, Longitudinal Copy-Number Alteration Analysis in Plasma Cell-Free DNA of Neuroendocrine Neoplasms is a Novel Specific Biomarker for Diagnosis, Prognosis, and Follow-up
Open the PDF for Longitudinal Copy-Number Alteration Analysis in Plasma Cell-Free DNA of Neuroendocrine Neoplasms is a Novel Specific Biomarker for Diagnosis, Prognosis, and Follow-up in another window
Includes: Supplementary data
Journal Articles

Safety and Antitumor Activity of α-PD-L1 Antibody as Monotherapy or in Combination with α-TIM-3 Antibody in Patients with Microsatellite Instability–High/Mismatch Repair–Deficient Tumors

Antoine Hollebecque, Hyun C. Chung, Maria J. de Miguel, Antoine Italiano, Jean-Pascal Machiels, Chia-Chi Lin, Neesha C. Dhani, Marc Peeters, Victor Moreno, Wu-Chou Su, Kay Hoong Chow, Violeta R. Galvao, Michelle Carlsen, Danni Yu, Anna M. Szpurka, Yumin Zhao, Shelly L. Schmidt, Leena Gandhi, Xiaojian Xu, Yung-Jue Bang
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (23): 6393–6404.
https://doi.org/10.1158/1078-0432.CCR-21-0261
Published: 01 December 2021
View article titled, Safety and Antitumor Activity of α-PD-L1 Antibody as Monotherapy or in Combination with α-TIM-3 Antibody in Patients with Microsatellite Instability–High/Mismatch Repair–Deficient Tumors
Open the PDF for Safety and Antitumor Activity of α-PD-L1 Antibody as Monotherapy or in Combination with α-TIM-3 Antibody in Patients with Microsatellite Instability–High/Mismatch Repair–Deficient Tumors in another window
Includes: Supplementary data
Journal Articles

Evaluation of Emergent Mutations in Circulating Cell-Free DNA and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Treated with Panitumumab in the ASPECCT Study

Marc Peeters, Timothy Price, Michael Boedigheimer, Tae Won Kim, Paul Ruff, Peter Gibbs, Anne Thomas, Gaston Demonty, Kristina Hool, Agnes Ang
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (4): 1216–1225.
https://doi.org/10.1158/1078-0432.CCR-18-2072
Published: 15 February 2019
View article titled, Evaluation of Emergent Mutations in Circulating Cell-Free DNA and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Treated with Panitumumab in the ASPECCT Study
Open the PDF for Evaluation of Emergent Mutations in Circulating Cell-Free DNA and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Treated with Panitumumab in the ASPECCT Study in another window
Includes: Supplementary data
Journal Articles

Impact of Emergent Circulating Tumor DNA RAS Mutation in Panitumumab-Treated Chemoresistant Metastatic Colorectal Cancer

Tae Won Kim, Marc Peeters, Anne Thomas, Peter Gibbs, Kristina Hool, Jianqi Zhang, Agnes Lee Ang, Bruce Allen Bach, Timothy Price
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (22): 5602–5609.
https://doi.org/10.1158/1078-0432.CCR-17-3377
Published: 15 November 2018
View article titled, Impact of Emergent Circulating Tumor DNA <em>RAS</em> Mutation in Panitumumab-Treated Chemoresistant Metastatic Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Phase I Dose-Escalation Study of the Anti-CD70 Antibody ARGX-110 in Advanced Malignancies

Philippe Aftimos, Christian Rolfo, Sylvie Rottey, Fritz Offner, Dominique Bron, Marie Maerevoet, Jean-Charles Soria, Mahan Moshir, Torsten Dreier, Luc Van Rompaey, Jean-Marie Michot, Karen Silence, Anna Hultberg, Domenica Gandini, Hans de Haard, Vincent Ribrag, Marc Peeters, Alain Thibault, Nicolas Leupin, Ahmad Awada
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (21): 6411–6420.
https://doi.org/10.1158/1078-0432.CCR-17-0613
Published: 31 October 2017
View article titled, Phase I Dose-Escalation Study of the Anti-CD70 Antibody ARGX-110 in Advanced Malignancies
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Includes: Supplementary data
Journal Articles

Analysis of KRAS/NRAS Mutations in a Phase III Study of Panitumumab with FOLFIRI Compared with FOLFIRI Alone as Second-line Treatment for Metastatic Colorectal Cancer

Marc Peeters, Kelly S. Oliner, Timothy J. Price, Andrés Cervantes, Alberto F. Sobrero, Michel Ducreux, Yevhen Hotko, Thierry André, Emily Chan, Florian Lordick, Cornelis J.A. Punt, Andrew H. Strickland, Gregory Wilson, Tudor E. Ciuleanu, Laslo Roman, Eric Van Cutsem, Pei He, Hua Yu, Reija Koukakis, Jan-Henrik Terwey, Andre S. Jung, Roger Sidhu, Scott D. Patterson
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (24): 5469–5479.
https://doi.org/10.1158/1078-0432.CCR-15-0526
Published: 14 December 2015
View article titled, Analysis of <em>KRAS</em>/<em>NRAS</em> Mutations in a Phase III Study of Panitumumab with FOLFIRI Compared with FOLFIRI Alone as Second-line Treatment for Metastatic Colorectal Cancer
Open the PDF for Analysis of <em>KRAS</em>/<em>NRAS</em> Mutations in a Phase III Study of Panitumumab with FOLFIRI Compared with FOLFIRI Alone as Second-line Treatment for Metastatic Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Massively Parallel Tumor Multigene Sequencing to Evaluate Response to Panitumumab in a Randomized Phase III Study of Metastatic Colorectal Cancer

Marc Peeters, Kelly S. Oliner, Alex Parker, Salvatore Siena, Eric Van Cutsem, Jing Huang, Yves Humblet, Jean-Luc Van Laethem, Thierry André, Jeffrey Wiezorek, David Reese, Scott D. Patterson
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (7): 1902–1912.
https://doi.org/10.1158/1078-0432.CCR-12-1913
Published: 02 April 2013
View article titled, Massively Parallel Tumor Multigene Sequencing to Evaluate Response to Panitumumab in a Randomized Phase III Study of Metastatic Colorectal Cancer
Open the PDF for Massively Parallel Tumor Multigene Sequencing to Evaluate Response to Panitumumab in a Randomized Phase III Study of Metastatic Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Human Equilibrative Nucleoside Transporter 1 and Human Concentrative Nucleoside Transporter 3 Predict Survival after Adjuvant Gemcitabine Therapy in Resected Pancreatic Adenocarcinoma

Raphaël Maréchal, John R. Mackey, Raymond Lai, Pieter Demetter, Marc Peeters, Marc Polus, Carol E. Cass, James Young, Isabelle Salmon, Jacques Devière, Jean-Luc Van Laethem
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (8): 2913–2919.
https://doi.org/10.1158/1078-0432.CCR-08-2080
Published: 15 April 2009
View article titled, Human Equilibrative Nucleoside Transporter 1 and Human Concentrative Nucleoside Transporter 3 Predict Survival after Adjuvant Gemcitabine Therapy in Resected Pancreatic Adenocarcinoma
Open the PDF for Human Equilibrative Nucleoside Transporter 1 and Human Concentrative Nucleoside Transporter 3 Predict Survival after Adjuvant Gemcitabine Therapy in Resected Pancreatic Adenocarcinoma in another window
Journal Articles

Clinical Usefulness of EGFR Gene Copy Number as a Predictive Marker in Colorectal Cancer Patients Treated with Cetuximab: A Fluorescent In situ Hybridization Study

Nicola Personeni, Steffen Fieuws, Hubert Piessevaux, Gert De Hertogh, Jef De Schutter, Bart Biesmans, Wendy De Roock, An Capoen, Maria Debiec-Rychter, Jean-Luc Van Laethem, Marc Peeters, Yves Humblet, Eric Van Cutsem, Sabine Tejpar
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (18): 5869–5876.
https://doi.org/10.1158/1078-0432.CCR-08-0449
Published: 14 September 2008
View article titled, Clinical Usefulness of <em>EGFR</em> Gene Copy Number as a Predictive Marker in Colorectal Cancer Patients Treated with Cetuximab: A Fluorescent <em>In situ</em> Hybridization Study
Open the PDF for Clinical Usefulness of <em>EGFR</em> Gene Copy Number as a Predictive Marker in Colorectal Cancer Patients Treated with Cetuximab: A Fluorescent <em>In situ</em> Hybridization Study in another window
Includes: Supplementary data