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Manish A. Shah
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Journal Articles

ILUSTRO: Phase II Multicohort Trial of Zolbetuximab in Patients with Advanced or Metastatic Claudin 18.2–Positive Gastric or Gastroesophageal Junction Adenocarcinoma

Samuel J. Klempner, Keun-Wook Lee, Kohei Shitara, Jean-Phillippe Metges, Sara Lonardi, David H. Ilson, Nicola Fazio, Tae Yong Kim, Li-Yuan Bai, Diarmuid Moran, Jianning Yang, Ahsan Arozullah, Jung Wook Park, Jeffrey J. Raizer, Yung-Jue Bang, Manish A. Shah
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (19): 3882–3891.
https://doi.org/10.1158/1078-0432.CCR-23-0204
Published: 02 October 2023
View article titled, ILUSTRO: Phase II Multicohort Trial of Zolbetuximab in Patients with Advanced or Metastatic Claudin 18.2–Positive Gastric or Gastroesophageal Junction Adenocarcinoma
Open the PDF for ILUSTRO: Phase II Multicohort Trial of Zolbetuximab in Patients with Advanced or Metastatic Claudin 18.2–Positive Gastric or Gastroesophageal Junction Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Randomized, Double-Blind, Placebo-Controlled Phase III Study of Paclitaxel ± Napabucasin in Pretreated Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Manish A. Shah, Kohei Shitara, Florian Lordick, Yung-Jue Bang, Niall C. Tebbutt, Jean-Phillippe Metges, Kei Muro, Keun-Wook Lee, Lin Shen, Sergei Tjulandin, John L. Hays, Naureen Starling, Rui-Hua Xu, Keren Sturtz, Marilyn Fontaine, Cindy Oh, Emily M. Brooks, Bo Xu, Wei Li, Chiang J. Li, Laura Borodyansky, Eric Van Cutsem
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (17): 3686–3694.
https://doi.org/10.1158/1078-0432.CCR-21-4021
Published: 02 September 2022
View article titled, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Paclitaxel ± Napabucasin in Pretreated Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Multicenter Phase II Study of Cabazitaxel in Advanced Gastroesophageal Cancer: Association of HER2 Expression and M2-Like Tumor-Associated Macrophages with Patient Outcome

Manish A. Shah, Peter Enzinger, Andrew H. Ko, Allyson J. Ocean, Philip Agop Philip, Prashant V. Thakkar, Kyle Cleveland, Yao Lu, Jeremy Kortmansky, Paul J. Christos, Chao Zhang, Navjot Kaur, Dina Elmonshed, Giuseppe Galletti, Sandipto Sarkar, Bhavneet Bhinder, Meredith E. Pittman, Olga Mikhaylovna Plotnikova, Nikita Kotlov, Felix Frenkel, Aleksander Bagaev, Olivier Elemento, Doron Betel, Paraskevi Giannakakou, Heinz-Josef Lenz
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (18): 4756–4766.
https://doi.org/10.1158/1078-0432.CCR-19-3920
Published: 15 September 2020
View article titled, Multicenter Phase II Study of Cabazitaxel in Advanced Gastroesophageal Cancer: Association of HER2 Expression and M2-Like Tumor-Associated Macrophages with Patient Outcome
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Journal Articles

Abstract S10-01: COVID-19 severity and outcomes in hospitalized patients with cancer at a New York City tertiary medical center: A matched cohort study

Gagandeep Brar, Laura C. Pinheiro, Michael Shusterman, Brandon Swed, Evgeniya Reshentnyak, Orysya Soroka, Frank Chen, Samuel Yamshon, John Vaughn, Peter Martin, Doru Paul, Manuel Hidalgo, Manish A. Shah
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (18_Supplement): S10-01.
https://doi.org/10.1158/1557-3265.COVID-19-S10-01
Published: 15 September 2020
View article titled, Abstract S10-01: COVID-19 severity and outcomes in hospitalized patients with cancer at a New York City tertiary medical center: A matched cohort study
Journal Articles

Microtubule Engagement with Taxane Is Altered in Taxane-Resistant Gastric Cancer

Giuseppe Galletti, Chao Zhang, Ada Gjyrezi, Kyle Cleveland, Jiaren Zhang, Sarah Powell, Prashant V. Thakkar, Doron Betel, Manish A. Shah, Paraskevi Giannakakou
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (14): 3771–3783.
https://doi.org/10.1158/1078-0432.CCR-19-3018
Published: 15 July 2020
View article titled, Microtubule Engagement with Taxane Is Altered in Taxane-Resistant Gastric Cancer
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Includes: Multimedia, Supplementary data
Journal Articles

Andecaliximab/GS-5745 Alone and Combined with mFOLFOX6 in Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Results from a Phase I Study

Manish A. Shah, Alexander Starodub, Sunil Sharma, Jordan Berlin, Manish Patel, Zev A. Wainberg, Jorge Chaves, Michael Gordon, Kevin Windsor, Carrie Baker Brachmann, Xi Huang, Greg Vosganian, Julia D. Maltzman, Victoria Smith, Jeffrey A. Silverman, Heinz-Josef Lenz, Johanna C. Bendell
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (16): 3829–3837.
https://doi.org/10.1158/1078-0432.CCR-17-2469
Published: 14 August 2018
View article titled, Andecaliximab/GS-5745 Alone and Combined with mFOLFOX6 in Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Results from a Phase I Study
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Includes: Supplementary data
Journal Articles

Phase I Study of Epigenetic Priming with Azacitidine Prior to Standard Neoadjuvant Chemotherapy for Patients with Resectable Gastric and Esophageal Adenocarcinoma: Evidence of Tumor Hypomethylation as an Indicator of Major Histopathologic Response

Bryan J. Schneider, Manish A. Shah, Kelsey Klute, Allyson Ocean, Elizabeta Popa, Nasser Altorki, Michael Lieberman, Andrew Schreiner, Rhonda Yantiss, Paul J. Christos, Romae Palmer, Daoqi You, Agnes Viale, Pouneh Kermani, Joseph M. Scandura
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (11): 2673–2680.
https://doi.org/10.1158/1078-0432.CCR-16-1896
Published: 31 May 2017
View article titled, Phase I Study of Epigenetic Priming with Azacitidine Prior to Standard Neoadjuvant Chemotherapy for Patients with Resectable Gastric and Esophageal Adenocarcinoma: Evidence of Tumor Hypomethylation as an Indicator of Major Histopathologic Response
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Includes: Supplementary data
Journal Articles

First-in-Human Trial of a Novel Anti-Trop-2 Antibody-SN-38 Conjugate, Sacituzumab Govitecan, for the Treatment of Diverse Metastatic Solid Tumors

Alexander N. Starodub, Allyson J. Ocean, Manish A. Shah, Michael J. Guarino, Vincent J. Picozzi, Jr, Linda T. Vahdat, Sajeve S. Thomas, Serengulam V. Govindan, Pius P. Maliakal, William A. Wegener, Steven A. Hamburger, Robert M. Sharkey, David M. Goldenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (17): 3870–3878.
https://doi.org/10.1158/1078-0432.CCR-14-3321
Published: 31 August 2015
View article titled, First-in-Human Trial of a Novel Anti-Trop-2 Antibody-SN-38 Conjugate, Sacituzumab Govitecan, for the Treatment of Diverse Metastatic Solid Tumors
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Includes: Supplementary data
Journal Articles

Molecular Classification of Gastric Cancer: A New Paradigm

Manish A. Shah, Raya Khanin, Laura Tang, Yelena Y. Janjigian, David S. Klimstra, Hans Gerdes, David P. Kelsen
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (9): 2693–2701.
https://doi.org/10.1158/1078-0432.CCR-10-2203
Published: 01 May 2011
View article titled, Molecular Classification of Gastric Cancer: A New Paradigm
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Includes: Supplementary data
Journal Articles

Phase I Study of Flavopiridol with Oxaliplatin and Fluorouracil/Leucovorin in Advanced Solid Tumors

Dana Rathkopf, Mark A. Dickson, Darren R. Feldman, Richard D. Carvajal, Manish A. Shah, Nian Wu, Robert Lefkowitz, Mithat Gonen, Lauren M. Cane, Heather J. Dials, Jennifer L. Winkelmann, George J. Bosl, Gary K. Schwartz
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (23): 7405–7411.
https://doi.org/10.1158/1078-0432.CCR-09-1502
Published: 30 November 2009
View article titled, Phase I Study of Flavopiridol with Oxaliplatin and Fluorouracil/Leucovorin in Advanced Solid Tumors
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Journal Articles

A Phase I Clinical Trial of the Sequential Combination of Irinotecan Followed by Flavopiridol

Manish A. Shah, Jeremy Kortmansky, Monica Motwani, Marija Drobnjak, Mithat Gonen, Sandy Yi, Amanda Weyerbacher, Carlos Cordon-Cardo, Robert Lefkowitz, Baruch Brenner, Eileen O'Reilly, Leonard Saltz, William Tong, David P. Kelsen, Gary K. Schwartz
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (10): 3836–3845.
https://doi.org/10.1158/1078-0432.CCR-04-2651
Published: 16 May 2005
View article titled, A Phase I Clinical Trial of the Sequential Combination of Irinotecan Followed by Flavopiridol
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Journal Articles

Drg1 Expression in 131 Colorectal Liver Metastases: Correlation with Clinical Variables and Patient Outcomes

Manish A. Shah, Nancy Kemeny, Amanda Hummer, Marija Drobnjak, Monica Motwani, Carlos Cordon-Cardo, Mithat Gonen, Gary K. Schwartz
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (9): 3296–3302.
https://doi.org/10.1158/1078-0432.CCR-04-2417
Published: 02 May 2005
View article titled, <em>Drg1</em> Expression in 131 Colorectal Liver Metastases: Correlation with Clinical Variables and Patient Outcomes
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Journal Articles

Augmentation of Apoptosis and Tumor Regression by Flavopiridol in the Presence of CPT-11 in Hct116 Colon Cancer Monolayers and Xenografts

Monica Motwani, Christoph Jung, Francis M. Sirotnak, Yuhong She, Manish A. Shah, Mithat Gonen, Gary K. Schwartz
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (12): 4209–4219.
Published: 01 December 2001
View article titled, Augmentation of Apoptosis and Tumor Regression by Flavopiridol in the Presence of CPT-11 in Hct116 Colon Cancer Monolayers and Xenografts
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Journal Articles

Cell Cycle-mediated Drug Resistance: An Emerging Concept in Cancer Therapy

Manish A. Shah, Gary K. Schwartz
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (8): 2168–2181.
Published: 01 August 2001
View article titled, Cell Cycle-mediated Drug Resistance: <subtitle>An Emerging Concept in Cancer Therapy</subtitle>
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