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Lynette M. Sholl
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Journal Articles

Clinicopathologic, Genomic, and Immunophenotypic Landscape of ATM Mutations in Non–Small Cell Lung Cancer

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Biagio Ricciuti, Arielle Elkrief, Joao Alessi, Xinan Wang, Yvonne Li, Hersh Gupta, Daniel M. Muldoon, Arrien A. Bertram, Federica Pecci, Giuseppe Lamberti, Alessandro Di Federico, Adriana Barrichello, Victor R. Vaz, Malini Gandhi, Elinton Lee, Geoffrey I. Shapiro, Hyesun Park, Mizuki Nishino, James Lindsay, Kristen D. Felt, Bijaya Sharma, Andrew D. Cherniack, Scott Rodig, Daniel R. Gomez, Narek Shaverdian, Mehrdad Rakaee, Chaitanya Bandlamudi, Marc Ladanyi, Pasi A. Janne, Adam J. Schoenfeld, Lynette M. Sholl, Mark M. Awad, Michael L. Cheng
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (13): 2540–2550.
https://doi.org/10.1158/1078-0432.CCR-22-3413
Published: 05 July 2023
View articletitled, Clinicopathologic, Genomic, and Immunophenotypic Landscape of ATM Mutations in Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

To Rb or Not to Rb: Uncovering Unique Subsets of Small Cell Lung Carcinoma

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Navin R. Mahadevan, Lynette M. Sholl
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (21): 4603–4605.
https://doi.org/10.1158/1078-0432.CCR-22-2187
Published: 01 November 2022
View articletitled, To Rb or Not to Rb: Uncovering Unique Subsets of Small Cell Lung Carcinoma
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Journal Articles

Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations

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Elio Adib, Katarzyna Klonowska, Krinio Giannikou, Khanh T. Do, Solida Pruitt-Thompson, Ketki Bhushan, Matthew I. Milstein, Jennifer Hedglin, Katherine E. Kargus, Lynette M. Sholl, Junko Tsuji, David M. Hyman, Anne Sisk, Geoffrey I. Shapiro, Hebert A. Vargas, James J. Harding, Martin H. Voss, Gopa Iyer, David J. Kwiatkowski
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (14): 3845–3853.
https://doi.org/10.1158/1078-0432.CCR-20-4548
Published: 15 July 2021
View articletitled, Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations
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Includes: Supplementary data
Journal Articles

Overcoming MET-Dependent Resistance to Selective RET Inhibition in Patients with RET Fusion–Positive Lung Cancer by Combining Selpercatinib with Crizotinib

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Ezra Y. Rosen, Melissa L. Johnson, Sarah E. Clifford, Romel Somwar, Jennifer F. Kherani, Jieun Son, Arrien A. Bertram, Monika A. Davare, Eric Gladstone, Elena V. Ivanova, Dahlia N. Henry, Elaine M. Kelley, Mika Lin, Marina S.D. Milan, Binoj C. Nair, Elizabeth A. Olek, Jenna E. Scanlon, Morana Vojnic, Kevin Ebata, Jaclyn F. Hechtman, Bob T. Li, Lynette M. Sholl, Barry S. Taylor, Marc Ladanyi, Pasi A. Jänne, S. Michael Rothenberg, Alexander Drilon, Geoffrey R. Oxnard
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (1): 34–42.
https://doi.org/10.1158/1078-0432.CCR-20-2278
Published: 04 January 2021
View articletitled, Overcoming MET-Dependent Resistance to Selective RET Inhibition in Patients with RET Fusion–Positive Lung Cancer by Combining Selpercatinib with Crizotinib
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Includes: Supplementary data
Journal Articles

Identification of a RAS-activating TMEM87A–RASGRF1 Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer

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Alissa J. Cooper, Yoshihisa Kobayashi, Dewey Kim, Sarah E. Clifford, Sasha Kravets, Suzanne E. Dahlberg, Emily S. Chambers, Jiaqi Li, Deepa Rangachari, Tom Nguyen, Daniel B. Costa, Michael S. Rabin, Nikhil Wagle, Lynette M. Sholl, Pasi A Jänne, Geoffrey R. Oxnard
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (15): 4072–4079.
https://doi.org/10.1158/1078-0432.CCR-20-0397
Published: 03 August 2020
View articletitled, Identification of a RAS-activating TMEM87A–RASGRF1 Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Impact of DNA Damage Response and Repair (DDR) Gene Mutations on Efficacy of PD-(L)1 Immune Checkpoint Inhibition in Non–Small Cell Lung Cancer

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Biagio Ricciuti, Gonzalo Recondo, Liam F. Spurr, Yvonne Y. Li, Giuseppe Lamberti, Deepti Venkatraman, Renato Umeton, Andrew D. Cherniack, Mizuki Nishino, Lynette M. Sholl, Geoffrey I. Shapiro, Mark M. Awad, Michael L. Cheng
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (15): 4135–4142.
https://doi.org/10.1158/1078-0432.CCR-19-3529
Published: 03 August 2020
View articletitled, Impact of DNA Damage Response and Repair (DDR) Gene Mutations on Efficacy of PD-(L)1 Immune Checkpoint Inhibition in Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Generation of Genetically Engineered Mouse Lung Organoid Models for Squamous Cell Lung Cancers Allows for the Study of Combinatorial Immunotherapy

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Josephine Hai, Hua Zhang, Jin Zhou, Zhong Wu, Ting Chen, Eleni Papadopoulos, Catríona M. Dowling, Val Pyon, Yuanwang Pan, Jie Bin Liu, Roderick T. Bronson, Heather Silver, Patrick H. Lizotte, Jiehui Deng, Joshua D. Campbell, Lynette M. Sholl, Christine Ng, Ming-Sound Tsao, Cassandra Thakurdin, Adam J. Bass, Kwok-Kin Wong
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (13): 3431–3442.
https://doi.org/10.1158/1078-0432.CCR-19-1627
Published: 01 July 2020
View articletitled, Generation of Genetically Engineered Mouse Lung Organoid Models for Squamous Cell Lung Cancers Allows for the Study of Combinatorial Immunotherapy
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Includes: Supplementary data
Journal Articles

Molecular Mechanisms of Acquired Resistance to MET Tyrosine Kinase Inhibitors in Patients with MET Exon 14–Mutant NSCLC

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Gonzalo Recondo, Magda Bahcall, Liam F. Spurr, Jianwei Che, Biagio Ricciuti, Giulia C. Leonardi, Ying-Chun Lo, Yvonne Y. Li, Giuseppe Lamberti, Tom Nguyen, Marina S.D. Milan, Deepti Venkatraman, Renato Umeton, Cloud P. Paweletz, Adem Albayrak, Andrew D. Cherniack, Kristin S. Price, Stephen R. Fairclough, Mizuki Nishino, Lynette M. Sholl, Geoffrey R. Oxnard, Pasi A. Jänne, Mark M. Awad
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11): 2615–2625.
https://doi.org/10.1158/1078-0432.CCR-19-3608
Published: 01 June 2020
View articletitled, Molecular Mechanisms of Acquired Resistance to MET Tyrosine Kinase Inhibitors in Patients with MET Exon 14–Mutant NSCLC
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Includes: Supplementary data
Journal Articles

Amplification of Wild-type KRAS Imparts Resistance to Crizotinib in MET Exon 14 Mutant Non–Small Cell Lung Cancer

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Magda Bahcall, Mark M. Awad, Lynette M. Sholl, Frederick H. Wilson, Man Xu, Stephen Wang, Sangeetha Palakurthi, Jihyun Choi, Elena V. Ivanova, Giulia C. Leonardi, Bryan C. Ulrich, Cloud P. Paweletz, Paul T. Kirschmeier, Masayuki Watanabe, Hideo Baba, Mizuki Nishino, Rebecca J. Nagy, Richard B. Lanman, Marzia Capelletti, Emily S. Chambers, Amanda J. Redig, Paul A. VanderLaan, Daniel B. Costa, Yu Imamura, Pasi A. Jänne
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (23): 5963–5976.
https://doi.org/10.1158/1078-0432.CCR-18-0876
Published: 03 December 2018
View articletitled, Amplification of Wild-type KRAS Imparts Resistance to Crizotinib in MET Exon 14 Mutant Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

The Impact of Smoking and TP53 Mutations in Lung Adenocarcinoma Patients with Targetable Mutations—The Lung Cancer Mutation Consortium (LCMC2)

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Dara L. Aisner, Lynette M. Sholl, Lynne D. Berry, Michael R. Rossi, Heidi Chen, Junya Fujimoto, Andre L. Moreira, Suresh S. Ramalingam, Liza C. Villaruz, Gregory A. Otterson, Eric Haura, Katerina Politi, Bonnie Glisson, Jeremy Cetnar, Edward B. Garon, Joan Schiller, Saiama N. Waqar, Lecia V. Sequist, Julie Brahmer, Yu Shyr, Kelly Kugler, Ignacio I. Wistuba, Bruce E. Johnson, John D. Minna, Mark G. Kris, Paul A. Bunn, David J. Kwiatkowski
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (5): 1038–1047.
https://doi.org/10.1158/1078-0432.CCR-17-2289
Published: 28 February 2018
View articletitled, The Impact of Smoking and TP53 Mutations in Lung Adenocarcinoma Patients with Targetable Mutations—The Lung Cancer Mutation Consortium (LCMC2)
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Includes: Supplementary data
Journal Articles

Identification of Existing Drugs That Effectively Target NTRK1 and ROS1 Rearrangements in Lung Cancer

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Curtis R. Chong, Magda Bahcall, Marzia Capelletti, Takayuki Kosaka, Dalia Ercan, Taebo Sim, Lynette M. Sholl, Mizuki Nishino, Bruce E. Johnson, Nathanael S. Gray, Pasi A. Jänne
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (1): 204–213.
https://doi.org/10.1158/1078-0432.CCR-15-1601
Published: 02 January 2017
View articletitled, Identification of Existing Drugs That Effectively Target NTRK1 and ROS1 Rearrangements in Lung Cancer
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Includes: Supplementary data
Journal Articles

PD-1 Inhibitor–Related Pneumonitis in Advanced Cancer Patients: Radiographic Patterns and Clinical Course

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Mizuki Nishino, Nikhil H. Ramaiya, Mark M. Awad, Lynette M. Sholl, Jennifer A. Maattala, Myriam Taibi, Hiroto Hatabu, Patrick A. Ott, Philippe F. Armand, F. Stephen Hodi
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (24): 6051–6060.
https://doi.org/10.1158/1078-0432.CCR-16-1320
Published: 15 December 2016
View articletitled, PD-1 Inhibitor–Related Pneumonitis in Advanced Cancer Patients: Radiographic Patterns and Clinical Course
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Journal Articles

Clinical and Molecular Characteristics of NF1-Mutant Lung Cancer

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Amanda J. Redig, Marzia Capelletti, Suzanne E. Dahlberg, Lynette M. Sholl, Stacy Mach, Caitlin Fontes, Yunling Shi, Poornima Chalasani, Pasi A. Jänne
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (13): 3148–3156.
https://doi.org/10.1158/1078-0432.CCR-15-2377
Published: 30 June 2016
View articletitled, Clinical and Molecular Characteristics of NF1-Mutant Lung Cancer
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Includes: Supplementary data
Journal Articles

Immunohistochemical Loss of LKB1 Is a Biomarker for More Aggressive Biology in KRAS-Mutant Lung Adenocarcinoma

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Antonio Calles, Lynette M. Sholl, Scott J. Rodig, Ashley K. Pelton, Jason L. Hornick, Mohit Butaney, Christine Lydon, Suzanne E. Dahlberg, Geoffrey R. Oxnard, David M. Jackman, Pasi A. Jänne
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (12): 2851–2860.
https://doi.org/10.1158/1078-0432.CCR-14-3112
Published: 14 June 2015
View articletitled, Immunohistochemical Loss of LKB1 Is a Biomarker for More Aggressive Biology in KRAS-Mutant Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Clinical, Pathologic, and Biologic Features Associated with BRAF Mutations in Non–Small Cell Lung Cancer

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Stephanie Cardarella, Atsuko Ogino, Mizuki Nishino, Mohit Butaney, Jeanne Shen, Christine Lydon, Beow Y. Yeap, Lynette M. Sholl, Bruce E. Johnson, Pasi A. Jänne
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (16): 4532–4540.
https://doi.org/10.1158/1078-0432.CCR-13-0657
Published: 13 August 2013
View articletitled, Clinical, Pathologic, and Biologic Features Associated with BRAF Mutations in Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Clinicopathologic Features and Long-term Outcomes of NUT Midline Carcinoma

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Daniel E. Bauer, Chelsey M. Mitchell, Kelly M. Strait, Christopher S. Lathan, Edward B. Stelow, Sonja C. Lüer, Somala Muhammed, Andrew G. Evans, Lynette M. Sholl, Juan Rosai, Eugenia Giraldi, Richard P. Oakley, Carlos Rodriguez-Galindo, Wendy B. London, Stephen E. Sallan, James E. Bradner, Christopher A. French
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (20): 5773–5779.
https://doi.org/10.1158/1078-0432.CCR-12-1153
Published: 14 October 2012
View articletitled, Clinicopathologic Features and Long-term Outcomes of NUT Midline Carcinoma
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Includes: Supplementary data
Journal Articles

Mutation-Specific Antibodies for the Detection of EGFR Mutations in Non–Small-Cell Lung Cancer

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Jian Yu, Susan Kane, Jiong Wu, Elisa Benedettini, Daiqiang Li, Cynthia Reeves, Gregory Innocenti, Randy Wetzel, Katherine Crosby, Alison Becker, Michelle Ferrante, Wan Cheung Cheung, Xiqiang Hong, Lucian R. Chirieac, Lynette M. Sholl, Herbert Haack, Bradley L. Smith, Roberto D. Polakiewicz, Yi Tan, Ting-Lei Gu, Massimo Loda, Xinmin Zhou, Michael J. Comb
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (9): 3023–3028.
https://doi.org/10.1158/1078-0432.CCR-08-2739
Published: 30 April 2009
View articletitled, Mutation-Specific Antibodies for the Detection of EGFR Mutations in Non–Small-Cell Lung Cancer
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Includes: Supplementary data