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Luke Whitesell
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Journal Articles

Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation

Alex M. Jaeger, Lauren Stopfer, Sunmin Lee, Giorgio Gaglia, Demi Sandel, Sandro Santagata, Nancy U. Lin, Jane B. Trepel, Forest White, Tyler Jacks, Susan Lindquist, Luke Whitesell
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (21): 6392–6405.
https://doi.org/10.1158/1078-0432.CCR-19-0596
Published: 01 November 2019
View article titled, Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation
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Includes: Supplementary data
Journal Articles

Abstract A28: Targeting the epigenetic state regulating cancer cell vulnerability to proteasome inhibition

Peter Tsvetkov, Ethan Sokol, Dexter Jin, Piyush Gupta, Sandro Santagata, Luke Whitesell, Susan Lindquist
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (1_Supplement): A28.
https://doi.org/10.1158/1557-3265.PMCCAVULN16-A28
Published: 02 January 2017
View article titled, Abstract A28: Targeting the epigenetic state regulating cancer cell vulnerability to proteasome inhibition
Journal Articles

Phase I Pharmacokinetic and Pharmacodynamic Study of 17-N-Allylamino-17-Demethoxygeldanamycin in Pediatric Patients with Recurrent or Refractory Solid Tumors: A Pediatric Oncology Experimental Therapeutics Investigators Consortium Study

Rochelle Bagatell, Lia Gore, Merrill J. Egorin, Richard Ho, Glenn Heller, Nichole Boucher, Eleanor G. Zuhowski, James A. Whitlock, Stephen P. Hunger, Aru Narendran, Howard M. Katzenstein, Robert J. Arceci, Jessica Boklan, Cynthia E. Herzog, Luke Whitesell, S. Percy Ivy, Tanya M. Trippett
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (6): 1783–1788.
https://doi.org/10.1158/1078-0432.CCR-06-1892
Published: 15 March 2007
View article titled, Phase I Pharmacokinetic and Pharmacodynamic Study of 17-<em>N</em>-Allylamino-17-Demethoxygeldanamycin in Pediatric Patients with Recurrent or Refractory Solid Tumors: A Pediatric Oncology Experimental Therapeutics Investigators Consortium Study
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Journal Articles

A Phase I Study of 17-Allylaminogeldanamycin in Relapsed/Refractory Pediatric Patients with Solid Tumors: A Children's Oncology Group Study

Brenda J. Weigel, Susan M. Blaney, Joel M. Reid, Stephanie L. Safgren, Rochelle Bagatell, John Kersey, Joseph P. Neglia, S. Percy Ivy, Ashish M. Ingle, Luke Whitesell, Richard J. Gilbertson, Mark Krailo, Matthew Ames, Peter C. Adamson
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (6): 1789–1793.
https://doi.org/10.1158/1078-0432.CCR-06-2270
Published: 15 March 2007
View article titled, A Phase I Study of 17-Allylaminogeldanamycin in Relapsed/Refractory Pediatric Patients with Solid Tumors: A Children's Oncology Group Study
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Journal Articles

Hormone-Refractory Breast Cancer Remains Sensitive to the Antitumor Activity of Heat Shock Protein 90 Inhibitors

Jason Beliakoff, Rochelle Bagatell, Gillian Paine-Murrieta, Charles W. Taylor, Anne E. Lykkesfeldt, Luke Whitesell
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (13): 4961–4971.
Published: 27 October 2003
View article titled, Hormone-Refractory Breast Cancer Remains Sensitive to the Antitumor Activity of Heat Shock Protein 90 Inhibitors
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Journal Articles

Destabilization of Steroid Receptors by Heat Shock Protein 90-binding Drugs: A Ligand-independent Approach to Hormonal Therapy of Breast Cancer

Rochelle Bagatell, Omar Khan, Gillian Paine-Murrieta, Charles W. Taylor, Shiro Akinaga, Luke Whitesell
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (7): 2076–2084.
Published: 01 July 2001
View article titled, Destabilization of Steroid Receptors by Heat Shock Protein 90-binding Drugs: <subtitle>A Ligand-independent Approach to Hormonal Therapy of Breast Cancer</subtitle>
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Journal Articles

Induction of a Heat Shock Factor 1-dependent Stress Response Alters the Cytotoxic Activity of Hsp90-binding Agents

Rochelle Bagatell, Gillian D. Paine-Murrieta, Charles W. Taylor, Elizabeth J. Pulcini, Shiro Akinaga, Ivor J. Benjamin, Luke Whitesell
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (8): 3312–3318.
Published: 01 August 2000
View article titled, Induction of a Heat Shock Factor 1-dependent Stress Response Alters the Cytotoxic Activity of Hsp90-binding Agents
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Journal Articles

Immunoprotective Activities of Multiple Chaperone Proteins Isolated from Murine B-Cell Leukemia/Lymphoma

Michael Graner, Amy Raymond, Davis Romney, Lin He, Luke Whitesell, Emmanuel Katsanis
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (3): 909–915.
Published: 01 March 2000
View article titled, Immunoprotective Activities of Multiple Chaperone Proteins Isolated from Murine B-Cell Leukemia/Lymphoma
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