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Luis Sanchez-Perez
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Journal Articles

4-1BB Agonism Averts TIL Exhaustion and Licenses PD-1 Blockade in Glioblastoma and Other Intracranial Cancers

Karolina I. Woroniecka, Kristen E. Rhodin, Cosette Dechant, Xiuyu Cui, Pakawat Chongsathidkiet, Daniel Wilkinson, Jessica Waibl-Polania, Luis Sanchez-Perez, Peter E. Fecci
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (6): 1349–1358.
https://doi.org/10.1158/1078-0432.CCR-19-1068
Published: 13 March 2020
View articletitled, 4-1BB Agonism Averts TIL Exhaustion and Licenses PD-1 Blockade in Glioblastoma and Other Intracranial Cancers
Open the PDF for 4-1BB Agonism Averts TIL Exhaustion and Licenses PD-1 Blockade in Glioblastoma and Other Intracranial Cancers in another window
Includes: Supplementary data
Journal Articles

Targeting PD-L1 Initiates Effective Antitumor Immunity in a Murine Model of Cushing Disease

Hanna R. Kemeny, Aladine A. Elsamadicy, S. Harrison Farber, Cosette D. Champion, Selena J. Lorrey, Pakawat Chongsathidkiet, Karolina I. Woroniecka, Xiuyu Cui, Steven H. Shen, Kristen E. Rhodin, Vadim Tsvankin, Jeffrey Everitt, Luis Sanchez-Perez, Patrick Healy, Roger E. McLendon, Patrick J. Codd, Ian F. Dunn, Peter E. Fecci
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (5): 1141–1151.
https://doi.org/10.1158/1078-0432.CCR-18-3486
Published: 02 March 2020
View articletitled, Targeting PD-L1 Initiates Effective Antitumor Immunity in a Murine Model of Cushing Disease
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Journal Articles

Brain Tumor Microenvironment and Host State: Implications for Immunotherapy

William Tomaszewski, Luis Sanchez-Perez, Thomas F. Gajewski, John H. Sampson
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (14): 4202–4210.
https://doi.org/10.1158/1078-0432.CCR-18-1627
Published: 15 July 2019
View articletitled, Brain Tumor Microenvironment and Host State: Implications for Immunotherapy
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Journal Articles

Preventing Lck Activation in CAR T Cells Confers Treg Resistance but Requires 4-1BB Signaling for Them to Persist and Treat Solid Tumors in Nonlymphodepleted Hosts

Carter M. Suryadevara, Rupen Desai, S. Harrison Farber, Bryan D. Choi, Adam M. Swartz, Steven H. Shen, Patrick C. Gedeon, David J. Snyder, James E. Herndon, II, Patrick Healy, Elizabeth A. Reap, Gary E. Archer, Peter E. Fecci, John H. Sampson, Luis Sanchez-Perez
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (1): 358–368.
https://doi.org/10.1158/1078-0432.CCR-18-1211
Published: 03 January 2019
View articletitled, Preventing Lck Activation in CAR T Cells Confers Treg Resistance but Requires 4-1BB Signaling for Them to Persist and Treat Solid Tumors in Nonlymphodepleted Hosts
Open the PDF for Preventing Lck Activation in CAR T Cells Confers Treg Resistance but Requires 4-1BB Signaling for Them to Persist and Treat Solid Tumors in Nonlymphodepleted Hosts in another window
Journal Articles

T-Cell Exhaustion Signatures Vary with Tumor Type and Are Severe in Glioblastoma

Karolina Woroniecka, Pakawat Chongsathidkiet, Kristen Rhodin, Hanna Kemeny, Cosette Dechant, S. Harrison Farber, Aladine A. Elsamadicy, Xiuyu Cui, Shohei Koyama, Christina Jackson, Landon J. Hansen, Tanner M. Johanns, Luis Sanchez-Perez, Vidyalakshmi Chandramohan, Yen-Rei Andrea Yu, Darell D. Bigner, Amber Giles, Patrick Healy, Glenn Dranoff, Kent J. Weinhold, Gavin P. Dunn, Peter E. Fecci
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (17): 4175–4186.
https://doi.org/10.1158/1078-0432.CCR-17-1846
Published: 04 September 2018
View articletitled, T-Cell Exhaustion Signatures Vary with Tumor Type and Are Severe in Glioblastoma
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Includes: Supplementary data
Journal Articles

A Rationally Designed Fully Human EGFRvIII:CD3-Targeted Bispecific Antibody Redirects Human T Cells to Treat Patient-derived Intracerebral Malignant Glioma

Patrick C. Gedeon, Teilo H. Schaller, Satish K. Chitneni, Bryan D. Choi, Chien-Tsun Kuan, Carter M. Suryadevara, David J. Snyder, Robert J. Schmittling, Scott E. Szafranski, Xiuyu Cui, Patrick N. Healy, James E. Herndon, II, Roger E. McLendon, Stephen T. Keir, Gary E. Archer, Elizabeth A. Reap, Luis Sanchez-Perez, Darell D. Bigner, John H. Sampson
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (15): 3611–3631.
https://doi.org/10.1158/1078-0432.CCR-17-0126
Published: 31 July 2018
View articletitled, A Rationally Designed Fully Human EGFRvIII:CD3-Targeted Bispecific Antibody Redirects Human T Cells to Treat Patient-derived Intracerebral Malignant Glioma
Open the PDF for A Rationally Designed Fully Human EGFRvIII:CD3-Targeted Bispecific Antibody Redirects Human T Cells to Treat Patient-derived Intracerebral Malignant Glioma in another window
Includes: Supplementary data
Journal Articles

Long-term Survival in Glioblastoma with Cytomegalovirus pp65-Targeted Vaccination

Kristen A. Batich, Elizabeth A. Reap, Gary E. Archer, Luis Sanchez-Perez, Smita K. Nair, Robert J. Schmittling, Pam Norberg, Weihua Xie, James E. Herndon, II, Patrick Healy, Roger E. McLendon, Allan H. Friedman, Henry S. Friedman, Darell Bigner, Gordana Vlahovic, Duane A. Mitchell, John H. Sampson
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (8): 1898–1909.
https://doi.org/10.1158/1078-0432.CCR-16-2057
Published: 13 April 2017
View articletitled, Long-term Survival in Glioblastoma with Cytomegalovirus pp65-Targeted Vaccination
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Includes: Supplementary data
Journal Articles

EGFRvIII mCAR-Modified T-Cell Therapy Cures Mice with Established Intracerebral Glioma and Generates Host Immunity against Tumor-Antigen Loss

John H. Sampson, Bryan D. Choi, Luis Sanchez-Perez, Carter M. Suryadevara, David J. Snyder, Catherine T. Flores, Robert J. Schmittling, Smita K. Nair, Elizabeth A. Reap, Pamela K. Norberg, James E. Herndon, II, Chien-Tsun Kuan, Richard A. Morgan, Steven A. Rosenberg, Laura A. Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (4): 972–984.
https://doi.org/10.1158/1078-0432.CCR-13-0709
Published: 16 February 2014
View articletitled, EGFRvIII mCAR-Modified T-Cell Therapy Cures Mice with Established Intracerebral Glioma and Generates Host Immunity against Tumor-Antigen Loss
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Journal Articles

Toll-like Receptors in Tumor Immunotherapy

Chrystal M. Paulos, Andrew Kaiser, Claudia Wrzesinski, Christian S. Hinrichs, Lydie Cassard, Andrea Boni, Pawel Muranski, Luis Sanchez-Perez, Douglas C. Palmer, Zhiya Yu, Paul A. Antony, Luca Gattinoni, Steven A. Rosenberg, Nicholas P. Restifo
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (18): 5280–5289.
https://doi.org/10.1158/1078-0432.CCR-07-1378
Published: 17 September 2007
View articletitled, Toll-like Receptors in Tumor Immunotherapy
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