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Ludovic Lacroix
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Journal Articles

Genomic Profiling of Metastatic Castration-Resistant Prostate Cancer Samples Resistant to Androgen Receptor Pathway Inhibitors

Naoual Menssouri, Loïc Poiraudeau, Carole Helissey, Ludovic Bigot, Jonathan Sabio, Tony Ibrahim, Cédric Pobel, Claudio Nicotra, Maud Ngo-Camus, Ludovic Lacroix, Etienne Rouleau, Lambros Tselikas, Anne Chauchereau, Félix Blanc-Durand, Alice Bernard-Tessier, Anna Patrikidou, Natacha Naoun, Ronan Flippot, Emeline Colomba, Alina Fuerea, Laurence Albiges, Pernelle Lavaud, Paul van de Wiel, Eveline den Biezen, Yvonne Wesseling-Rozendaal, Santiago Ponce, Stefan Michiels, Christophe Massard, Daniel Gautheret, Fabrice Barlesi, Fabrice André, Benjamin Besse, Jean-Yves Scoazec, Luc Friboulet, Karim Fizazi, Yohann Loriot
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (21): 4504–4517.
https://doi.org/10.1158/1078-0432.CCR-22-3736
Published: 01 November 2023
View article titled, Genomic Profiling of Metastatic Castration-Resistant Prostate Cancer Samples Resistant to Androgen Receptor Pathway Inhibitors
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Includes: Supplementary data
Journal Articles

A Phase II Redifferentiation Trial with Dabrafenib-Trametinib and 131I in Metastatic Radioactive Iodine Refractory BRAF p.V600E-Mutated Differentiated Thyroid Cancer

Sophie Leboulleux, Christine Do Cao, Slimane Zerdoud, Marie Attard, Claire Bournaud, Ludovic Lacroix, Danielle Benisvy, David Taïeb, Stéphane Bardet, Marie Terroir-Cassou-Mounat, Nadège Anizan, Emilie Bouvier-Morel, Livia Lamartina, Georges Lion, Sarah Betrian, Christophe Sajous, Aurélie Schiazza, Marie-Eve Garcia, Renaud Ciappuccini, Martin Schlumberger, Abir Al Ghuzlan, Yann Godbert, Isabelle Borget
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (13): 2401–2409.
https://doi.org/10.1158/1078-0432.CCR-23-0046
Published: 05 July 2023
View article titled, A Phase II Redifferentiation Trial with Dabrafenib-Trametinib and <sup>131</sup>I in Metastatic Radioactive Iodine Refractory <em>BRAF</em> p.V600E-Mutated Differentiated Thyroid Cancer
Open the PDF for A Phase II Redifferentiation Trial with Dabrafenib-Trametinib and <sup>131</sup>I in Metastatic Radioactive Iodine Refractory <em>BRAF</em> p.V600E-Mutated Differentiated Thyroid Cancer in another window
Includes: Supplementary data
Journal Articles

Comparative Genomic Profiling of Second Breast Cancers following First Ipsilateral Hormone Receptor–Positive Breast Cancers

Elie Rassy, Ingrid Garberis, Alicia Tran-Dien, Bastien Job, Véronique Chung-Scott, Ibrahim Bouakka, Josiane Bassil, Rachel Ferkh, Magali Lacroix-Triki, Fabrizio Zanconati, Fabiola Giudici, Daniele Generali, Etienne Rouleau, Ludovic Lacroix, Fabrice Andre, Barbara Pistilli
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (9): 1822–1831.
https://doi.org/10.1158/1078-0432.CCR-22-2883
Published: 01 May 2023
View article titled, Comparative Genomic Profiling of Second Breast Cancers following First Ipsilateral Hormone Receptor–Positive Breast Cancers
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Journal Articles

Comprehensive Genome Profiling in Patients With Metastatic Non–Small Cell Lung Cancer: The Precision Medicine Phase II Randomized SAFIR02-Lung/IFCT 1301 Trial

Fabrice Barlesi, Pascale Tomasini, Maryam Karimi, Stefan Michiels, Judith Raimbourg, Catherine Daniel, Henri Janicot, Anne Madroszyk, Clarisse Audigier-Valette, Elisabeth Quoix, Julien Mazieres, Denis Moro-Sibilot, Eric Dansin, Olivier Molinier, Hugues Morel, Eric Pichon, Alexis Cortot, Josiane Otto, François Chomy, Pierre-Jean Souquet, Nicolas Cloarec, Etienne Giroux-Leprieur, Ivan Bieche, Ludovic Lacroix, Sandrine Boyault, Valery Attignon, Isabelle Soubeyran, Alain Morel, Alicia Tran-Dien, Alexandra Jacquet, Filippo Gustavo Dall'Olio, Marta Jimenez, Jean-Charles Soria, Benjamin Besse
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18): 4018–4026.
https://doi.org/10.1158/1078-0432.CCR-22-0371
Published: 15 September 2022
View article titled, Comprehensive Genome Profiling in Patients With Metastatic Non–Small Cell Lung Cancer: The Precision Medicine Phase II Randomized SAFIR02-Lung/IFCT 1301 Trial
Open the PDF for Comprehensive Genome Profiling in Patients With Metastatic Non–Small Cell Lung Cancer: The Precision Medicine Phase II Randomized SAFIR02-Lung/IFCT 1301 Trial in another window
Includes: Supplementary data
Journal Articles

Circulating Tumor DNA Genomics Reveal Potential Mechanisms of Resistance to BRAF-Targeted Therapies in Patients with BRAF-Mutant Metastatic Non–Small Cell Lung Cancer

Sandra Ortiz-Cuaran, Laura Mezquita, Aurélie Swalduz, Mihalea Aldea, Julien Mazieres, Camille Leonce, Cecile Jovelet, Anne Pradines, Virginie Avrillon, Washington R. Chumbi Flores, Ludovic Lacroix, Yohann Loriot, Virginie Westeel, Maud Ngo-Camus, Claire Tissot, Christine Raynaud, Radj Gervais, Etienne Brain, Isabelle Monnet, Etienne Giroux Leprieur, Caroline Caramella, Celine Mahier-Aït Oukhatar, Natalie Hoog-Labouret, Frank de Kievit, Karen Howarth, Clive Morris, Emma Green, Luc Friboulet, Sylvie Chabaud, Jean-François Guichou, Maurice Perol, Benjamin Besse, Jean-Yves Blay, Pierre Saintigny, David Planchard
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (23): 6242–6253.
https://doi.org/10.1158/1078-0432.CCR-20-1037
Published: 01 December 2020
View article titled, Circulating Tumor DNA Genomics Reveal Potential Mechanisms of Resistance to BRAF-Targeted Therapies in Patients with <em>BRAF</em>-Mutant Metastatic Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Diverse Resistance Mechanisms to the Third-Generation ALK Inhibitor Lorlatinib in ALK-Rearranged Lung Cancer

Gonzalo Recondo, Laura Mezquita, Francesco Facchinetti, David Planchard, Anas Gazzah, Ludovic Bigot, Ahsan Z. Rizvi, Rosa L. Frias, Jean Paul Thiery, Jean-Yves Scoazec, Tony Sourisseau, Karen Howarth, Olivier Deas, Dariia Samofalova, Justine Galissant, Pauline Tesson, Floriane Braye, Charles Naltet, Pernelle Lavaud, Linda Mahjoubi, Aurélie Abou Lovergne, Gilles Vassal, Rastilav Bahleda, Antoine Hollebecque, Claudio Nicotra, Maud Ngo-Camus, Stefan Michiels, Ludovic Lacroix, Catherine Richon, Nathalie Auger, Thierry De Baere, Lambros Tselikas, Eric Solary, Eric Angevin, Alexander M. Eggermont, Fabrice Andre, Christophe Massard, Ken A. Olaussen, Jean-Charles Soria, Benjamin Besse, Luc Friboulet
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (1): 242–255.
https://doi.org/10.1158/1078-0432.CCR-19-1104
Published: 03 January 2020
View article titled, Diverse Resistance Mechanisms to the Third-Generation ALK Inhibitor Lorlatinib in ALK-Rearranged Lung Cancer
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Includes: Supplementary data
Journal Articles

Acquired Resistance Mutations to ALK Inhibitors Identified by Single Circulating Tumor Cell Sequencing in ALK-Rearranged Non–Small-Cell Lung Cancer

Emma Pailler, Vincent Faugeroux, Marianne Oulhen, Laura Mezquita, Mélanie Laporte, Aurélie Honoré, Yann Lecluse, Pauline Queffelec, Maud NgoCamus, Claudio Nicotra, Jordi Remon, Ludovic Lacroix, David Planchard, Luc Friboulet, Benjamin Besse, Françoise Farace
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (22): 6671–6682.
https://doi.org/10.1158/1078-0432.CCR-19-1176
Published: 15 November 2019
View article titled, Acquired Resistance Mutations to ALK Inhibitors Identified by Single Circulating Tumor Cell Sequencing in <em>ALK</em>-Rearranged Non–Small-Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Molecular Screening for Cancer Treatment Optimization (MOSCATO-01) in Pediatric Patients: A Single-Institutional Prospective Molecular Stratification Trial

Anne C. Harttrampf, Ludovic Lacroix, Marc Deloger, Frederic Deschamps, Stephanie Puget, Nathalie Auger, Philippe Vielh, Pascale Varlet, Zsofia Balogh, Samuel Abbou, Adrien Allorant, Dominique Valteau-Couanet, Sabine Sarnacki, Louise Gamiche-Rolland, Guillaume Meurice, Veronique Minard-Colin, Jacques Grill, Laurence Brugieres, Christelle Dufour, Nathalie Gaspar, Stefan Michiels, Gilles Vassal, Jean-Charles Soria, Birgit Geoerger
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (20): 6101–6112.
https://doi.org/10.1158/1078-0432.CCR-17-0381
Published: 12 October 2017
View article titled, Molecular Screening for Cancer Treatment Optimization (MOSCATO-01) in Pediatric Patients: A Single-Institutional Prospective Molecular Stratification Trial
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Includes: Supplementary data
Journal Articles

Crizotinib-Resistant ROS1 Mutations Reveal a Predictive Kinase Inhibitor Sensitivity Model for ROS1- and ALK-Rearranged Lung Cancers

Francesco Facchinetti, Yohann Loriot, Mei-Shiue Kuo, Linda Mahjoubi, Ludovic Lacroix, David Planchard, Benjamin Besse, Françoise Farace, Nathalie Auger, Jordi Remon, Jean-Yves Scoazec, Fabrice André, Jean-Charles Soria, Luc Friboulet
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (24): 5983–5991.
https://doi.org/10.1158/1078-0432.CCR-16-0917
Published: 15 December 2016
View article titled, Crizotinib-Resistant <em>ROS1</em> Mutations Reveal a Predictive Kinase Inhibitor Sensitivity Model for <em>ROS1</em>- and <em>ALK</em>-Rearranged Lung Cancers
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Includes: Supplementary data
Journal Articles

Circulating Cell-Free Tumor DNA Analysis of 50 Genes by Next-Generation Sequencing in the Prospective MOSCATO Trial

Cécile Jovelet, Ecaterina Ileana, Marie-Cécile Le Deley, Nelly Motté, Silvia Rosellini, Alfredo Romero, Celine Lefebvre, Marion Pedrero, Noémie Pata-Merci, Nathalie Droin, Marc Deloger, Christophe Massard, Antoine Hollebecque, Charles Ferté, Amélie Boichard, Sophie Postel-Vinay, Maud Ngo-Camus, Thierry De Baere, Philippe Vielh, Jean-Yves Scoazec, Gilles Vassal, Alexander Eggermont, Fabrice André, Jean-Charles Soria, Ludovic Lacroix
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (12): 2960–2968.
https://doi.org/10.1158/1078-0432.CCR-15-2470
Published: 14 June 2016
View article titled, Circulating Cell-Free Tumor DNA Analysis of 50 Genes by Next-Generation Sequencing in the Prospective MOSCATO Trial
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Includes: Supplementary data
Journal Articles

Characterization of a Large Panel of Patient-Derived Tumor Xenografts Representing the Clinical Heterogeneity of Human Colorectal Cancer

Sylvia Julien, Ana Merino-Trigo, Ludovic Lacroix, Marc Pocard, Diane Goéré, Pascale Mariani, Sophie Landron, Ludovic Bigot, Fariba Nemati, Peggy Dartigues, Louis-Bastien Weiswald, Denis Lantuas, Loïc Morgand, Emmanuel Pham, Patrick Gonin, Virginie Dangles-Marie, Bastien Job, Philippe Dessen, Alain Bruno, Alain Pierré, Hugues De Thé, Hany Soliman, Manoel Nunes, Guillaume Lardier, Loreley Calvet, Brigitte Demers, Grégoire Prévost, Patricia Vrignaud, Sergio Roman-Roman, Olivier Duchamp, Cyril Berthet
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (19): 5314–5328.
https://doi.org/10.1158/1078-0432.CCR-12-0372
Published: 30 September 2012
View article titled, Characterization of a Large Panel of Patient-Derived Tumor Xenografts Representing the Clinical Heterogeneity of Human Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Biomarker Discovery, Development, and Implementation in France: A Report from the French National Cancer Institute and Cooperative Groups

Fabrice Andre, Frederique Nowak, Monica Arnedos, Ludovic Lacroix, Patrice Viens, Fabien Calvo
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (6): 1555–1560.
https://doi.org/10.1158/1078-0432.CCR-11-2201
Published: 14 March 2012
View article titled, Biomarker Discovery, Development, and Implementation in France: A Report from the French National Cancer Institute and Cooperative Groups
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Journal Articles

Abstract B45: Upfront genomic testing in non-small cell lung cancer (NSCLC) patients: Preliminary result of the MSN study

David Planchard, Ludovic Lacroix, Thierry Le Chevalier, Jean-Charles Soria, Benjamin Besse, Aljosa Celebic, Maud Ngocamus, Nathalie Auger, Beranger Lueza, Patrick Saulnier, Arslane Rahal, Khadja Kalai, Peter Dorfmuller
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3_Supplement): B45.
https://doi.org/10.1158/1078-0432.12AACRIASLC-B45
Published: 01 February 2012
View article titled, Abstract B45: Upfront genomic testing in non-small cell lung cancer (NSCLC) patients: Preliminary result of the MSN study
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Journal Articles

Skin Tumors Induced by Sorafenib; Paradoxic RAS–RAF Pathway Activation and Oncogenic Mutations of HRAS, TP53, and TGFBR1

Jean Philippe Arnault, Christine Mateus, Bernard Escudier, Gorana Tomasic, Janine Wechsler, Emilie Hollville, Jean-Charles Soria, David Malka, Alain Sarasin, Magalie Larcher, Jocelyne André, Nyam Kamsu-Kom, Lise Boussemart, Ludovic Lacroix, Alain Spatz, Alexander M. Eggermont, Sabine Druillennec, Stephan Vagner, Alain Eychène, Nicolas Dumaz, Caroline Robert
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (1): 263–272.
https://doi.org/10.1158/1078-0432.CCR-11-1344
Published: 02 January 2012
View article titled, Skin Tumors Induced by Sorafenib; Paradoxic RAS–RAF Pathway Activation and Oncogenic Mutations of <em>HRAS</em>, <em>TP53</em>, and <em>TGFBR1</em>
Open the PDF for Skin Tumors Induced by Sorafenib; Paradoxic RAS–RAF Pathway Activation and Oncogenic Mutations of <em>HRAS</em>, <em>TP53</em>, and <em>TGFBR1</em> in another window
Includes: Supplementary data
Journal Articles

Molecular Characteristics of ERCC1-Negative versus ERCC1-Positive Tumors in Resected NSCLC

Luc Friboulet, Daniel Barrios-Gonzales, Frédéric Commo, Ken André Olaussen, Stephan Vagner, Julien Adam, Aïcha Goubar, Nicolas Dorvault, Vladimir Lazar, Bastien Job, Benjamin Besse, Pierre Validire, Philippe Girard, Ludovic Lacroix, Johanna Hasmats, Fabienne Dufour, Fabrice André, Jean-Charles Soria
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (17): 5562–5572.
https://doi.org/10.1158/1078-0432.CCR-11-0790
Published: 01 September 2011
View article titled, Molecular Characteristics of ERCC1-Negative versus ERCC1-Positive Tumors in Resected NSCLC
Open the PDF for Molecular Characteristics of ERCC1-Negative versus ERCC1-Positive Tumors in Resected NSCLC in another window
Includes: Supplementary data
Journal Articles

Identification of Soluble Candidate Biomarkers of Therapeutic Response to Sunitinib in Medullary Thyroid Carcinoma in Preclinical Models

Sophie Broutin, Nabahet Ameur, Ludovic Lacroix, Thomas Robert, Benoit Petit, Nassima Oumata, Monique Talbot, Bernard Caillou, Martin Schlumberger, Corinne Dupuy, Jean-Michel Bidart
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (7): 2044–2054.
https://doi.org/10.1158/1078-0432.CCR-10-2041
Published: 31 March 2011
View article titled, Identification of Soluble Candidate Biomarkers of Therapeutic Response to Sunitinib in Medullary Thyroid Carcinoma in Preclinical Models
Open the PDF for Identification of Soluble Candidate Biomarkers of Therapeutic Response to Sunitinib in Medullary Thyroid Carcinoma in Preclinical Models in another window
Includes: Supplementary data