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Lloyd R. Kelland
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Journal Articles

In vitro and In vivo Pharmacokinetic-Pharmacodynamic Relationships for the Trisubstituted Aminopurine Cyclin-Dependent Kinase Inhibitors Olomoucine, Bohemine and CYC202

Florence I. Raynaud, Steven R. Whittaker, Peter M. Fischer, Steven McClue, Michael I. Walton, S. Elaine Barrie, Michelle D. Garrett, Paul Rogers, Simon J. Clarke, Lloyd R. Kelland, Melanie Valenti, Lisa Brunton, Suzanne Eccles, David P. Lane, Paul Workman
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (13): 4875–4887.
https://doi.org/10.1158/1078-0432.CCR-04-2264
Published: 01 July 2005
View article titled, <em>In vitro</em> and <em>In vivo</em> Pharmacokinetic-Pharmacodynamic Relationships for the Trisubstituted Aminopurine Cyclin-Dependent Kinase Inhibitors Olomoucine, Bohemine and CYC202
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Journal Articles

Tumor Dose Response to the Vascular Disrupting Agent, 5,6-Dimethylxanthenone-4-Acetic Acid, Using In vivo Magnetic Resonance Spectroscopy

Lesley D. McPhail, Yuen-Li Chung, Basetti Madhu, Simon Clark, John R. Griffiths, Lloyd R. Kelland, Simon P. Robinson
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (10): 3705–3713.
https://doi.org/10.1158/1078-0432.CCR-04-2504
Published: 16 May 2005
View article titled, Tumor Dose Response to the Vascular Disrupting Agent, 5,6-Dimethylxanthenone-4-Acetic Acid, Using <em>In vivo</em> Magnetic Resonance Spectroscopy
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Journal Articles

Establishment and Characterization of Acquired Resistance to the Farnesyl Protein Transferase Inhibitor R115777 in a Human Colon Cancer Cell Line

Victoria Smith, Martin G. Rowlands, Elaine Barrie, Paul Workman, Lloyd R. Kelland
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (6): 2002–2009.
Published: 01 June 2002
View article titled, Establishment and Characterization of Acquired Resistance to the Farnesyl Protein Transferase Inhibitor R115777 in a Human Colon Cancer Cell Line
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Journal Articles

Preclinical Antitumor Activity and Pharmacodynamic Studies with the Farnesyl Protein Transferase Inhibitor R115777 in Human Breast Cancer

Lloyd R. Kelland, Vicki Smith, Melanie Valenti, Lisa Patterson, Paul A. Clarke, Simone Detre, Dave End, Angela J. Howes, Mitch Dowsett, Paul Workman, Stephen R. D. Johnston
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (11): 3544–3550.
Published: 01 November 2001
View article titled, Preclinical Antitumor Activity and Pharmacodynamic Studies with the Farnesyl Protein Transferase Inhibitor R115777 in Human Breast Cancer
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Journal Articles

In Vitro Prevention of the Emergence of Multidrug Resistance in a Pediatric Rhabdomyosarcoma Cell Line

Hilary A. Cocker, Nicki Tiffin, Kathy Pritchard-Jones, C. Ross Pinkerton, Lloyd R. Kelland
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (10): 3193–3198.
Published: 01 October 2001
View article titled, <em>In Vitro</em> Prevention of the Emergence of Multidrug Resistance in a Pediatric Rhabdomyosarcoma Cell Line
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Journal Articles

BBR 3464: A Novel Triplatinum Complex, Exhibiting a Preclinical Profile of Antitumor Efficacy Different from Cisplatin

Carla Manzotti, Graziella Pratesi, Ernesto Menta, Roberto Di Domenico, Ennio Cavalletti, Heinz H. Fiebig, Lloyd R. Kelland, Nicholas Farrell, Donatella Polizzi, Rosanna Supino, Gabriella Pezzoni, Franco Zunino
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (7): 2626–2634.
Published: 01 July 2000
View article titled, BBR 3464: A Novel Triplatinum Complex, Exhibiting a Preclinical Profile of Antitumor Efficacy Different from Cisplatin
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