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Lionel D. Lewis
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Journal Articles

AMPK Activation by Metformin Promotes Survival of Dormant ER+ Breast Cancer Cells

Riley A. Hampsch, Jason D. Wells, Nicole A. Traphagen, Charlotte F. McCleery, Jennifer L. Fields, Kevin Shee, Lloye M. Dillon, Darcy B. Pooler, Lionel D. Lewis, Eugene Demidenko, Yina H. Huang, Jonathan D. Marotti, Abigail E. Goen, William B. Kinlaw, Todd W. Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (14): 3707–3719.
https://doi.org/10.1158/1078-0432.CCR-20-0269
Published: 15 July 2020
View article titled, AMPK Activation by Metformin Promotes Survival of Dormant ER<sup>+</sup> Breast Cancer Cells
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Includes: Supplementary data
Journal Articles

Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha–Positive, PIK3CA-Mutant Breast Cancer

Wei Yang, Sarah R. Hosford, Lloye M. Dillon, Kevin Shee, Stephanie C. Liu, Jennifer R. Bean, Laurent Salphati, Jodie Pang, Xiaolin Zhang, Michelle A. Nannini, Eugene Demidenko, Darcy Bates, Lionel D. Lewis, Jonathan D. Marotti, Alan R. Eastman, Todd W. Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (9): 2250–2260.
https://doi.org/10.1158/1078-0432.CCR-15-2276
Published: 01 May 2016
View article titled, Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha–Positive, <em>PIK3CA</em>-Mutant Breast Cancer
Open the PDF for Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha–Positive, <em>PIK3CA</em>-Mutant Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Might Cigarettes Be a “Smoking Gun” to Reduce Taxane Myelotoxicity?

Lionel D. Lewis, Mark J. Ratain
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (16): 4219–4221.
https://doi.org/10.1158/1078-0432.CCR-12-1713
Published: 14 August 2012
View article titled, Might Cigarettes Be a “Smoking Gun” to Reduce Taxane Myelotoxicity?
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Includes: Supplementary data
Journal Articles

A Comparison of the Pharmacokinetics and Pharmacodynamics of Docetaxel between African-American and Caucasian Cancer Patients: CALGB 9871

Lionel D. Lewis, Antonius A. Miller, Gary L. Rosner, Jonathan E. Dowell, Manuel Valdivieso, Mary V. Relling, Merrill J. Egorin, Robert R. Bies, Donna R. Hollis, Ellis G. Levine, Gregory A. Otterson, Frederick Millard, Mark J. Ratain, for the Cancer and Leukemia Group B
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (11): 3302–3311.
https://doi.org/10.1158/1078-0432.CCR-06-2345
Published: 01 June 2007
View article titled, A Comparison of the Pharmacokinetics and Pharmacodynamics of Docetaxel between African-American and Caucasian Cancer Patients: CALGB 9871
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Journal Articles

Phase I and Pharmacokinetic Study of AI-850, A Novel Microparticle Hydrophobic Drug Delivery System for Paclitaxel

Alain C. Mita, Anthony J. Olszanski, Richard C. Walovitch, Raymond P. Perez, Kathleen MacKay, David P. Tuck, Cecilia Simmons, Susan Hammond, Monica M. Mita, Muralidhar Beeram, Anne J. Stone, Eric K. Rowinsky, Lionel D. Lewis
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (11): 3293–3301.
https://doi.org/10.1158/1078-0432.CCR-06-2496
Published: 01 June 2007
View article titled, Phase I and Pharmacokinetic Study of AI-850, A Novel Microparticle Hydrophobic Drug Delivery System for Paclitaxel
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Journal Articles

A Proof-of-Principle Clinical Trial of Bexarotene in Patients with Non–Small Cell Lung Cancer

Konstantin H. Dragnev, W. Jeffrey Petty, Sumit J. Shah, Lionel D. Lewis, Candice C. Black, Vincent Memoli, William C. Nugent, Thomas Hermann, Andres Negro-Vilar, James R. Rigas, Ethan Dmitrovsky
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (6): 1794–1800.
https://doi.org/10.1158/1078-0432.CCR-06-1836
Published: 15 March 2007
View article titled, A Proof-of-Principle Clinical Trial of Bexarotene in Patients with Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Modulation of Cell Cycle Progression in Human Tumors: A Pharmacokinetic and Tumor Molecular Pharmacodynamic Study of Cisplatin Plus the Chk1 Inhibitor UCN-01 (NSC 638850)

Raymond P. Perez, Lionel D. Lewis, Andrew P. Beelen, Anthony J. Olszanski, Nicholas Johnston, C. Harker Rhodes, Bernard Beaulieu, Marc S. Ernstoff, Alan Eastman
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (23): 7079–7085.
https://doi.org/10.1158/1078-0432.CCR-06-0197
Published: 04 December 2006
View article titled, Modulation of Cell Cycle Progression in Human Tumors: A Pharmacokinetic and Tumor Molecular Pharmacodynamic Study of Cisplatin Plus the Chk1 Inhibitor UCN-01 (NSC 638850)
Open the PDF for Modulation of Cell Cycle Progression in Human Tumors: A Pharmacokinetic and Tumor Molecular Pharmacodynamic Study of Cisplatin Plus the Chk1 Inhibitor UCN-01 (NSC 638850) in another window